Click here to switch to the map view.

The map label for this gene is HypE_2 [C]

Identifier: 20094980

GI number: 20094980

Start: 1562041

End: 1563039

Strand: Reverse

Name: HypE_2 [C]

Synonym: MK1544

Alternate gene names: 20094980

Gene position: 1563039-1562041 (Counterclockwise)

Preceding gene: 20094982

Following gene: 20094979

Centisome position: 92.22

GC content: 61.36

Gene sequence:

>999_bases
GTGAGTAAAGTACGCCGCGAACACGGGGCCGGTGGAGAGCTCATGGAGTCCCTGATCAAGGAGGAGCTGCTGCCCAACCT
GACGATGCGCGGCGAAGGGTCGGTTACGCTGGATGACCTCGACGACGGGGCGACGTTCCCTTCCGTCGACGGTGAAATGG
TGATGACGACCGACGCGCACATCGTAGACCCACCGTTTTTCCCCGGAGGGAACGTGGGTAAACTCGCGGCCGCGGGCACG
GCCAACGACCTCGCCGTTATGGGCGCGAAGCCCGTAGCCTTCGCGTGCTCCATCGTAGTGCGCGAGGGATTCCCCATCGA
CGATCTGAAGCGTGTGTACCGTTCAATCGACGGGGTACTGAGCGAGTTGGGCGCTCATCTGATCACCGGCGACACTAAGG
TCGGAAACACGGGGGACGTCGATATCGTCGTCACCATGACCGGTGTGGGTGAGATCGTCGAACTTGTCCGAGACTGTGGT
CTCAGGCCCGGTGATAAGATCGTCATCACGGGTACGGTAGGAGACCATGGGATGGCGATCCTGGCGGCCCAGCAGGGATT
GGATACGGATCTCGAATCCGACGTGGCTCCGGTGTGGGAAGCCGTCAACGCAGCGCTCGAGGTCGGTGGAGTCACTTCGA
TGAAGGATCCCACCCGAGGAGGCCTCGCCGGAGCTCTGAACGAGATGGCGGAGAAGTCGGGTGTACGGATCGTAATCGAG
GAGGAGCGGATCCCAATTCGAGAGGAGGTCCGAGTGCTCTCGGAGATGCTGGGTGTCAATCCTCTGGAGGTGGCGAACGA
GGGCAAAGTCGTCATGGGAGTCCGTCCGGATATGGTCGATGACGTGCTCGACGCTATCCGCTCCACCGAGGTCGGCAAAA
ACGCCGAGGTGATAGGAGTCGTGGAAGAGGGCACACCACGCGTCGAGATGGAAACCGAAGTCGGTGGCCGGAGAATAGTG
GAAAAGCCCGTCGGAGATCCGGTACCACGGGTGTGCTGA

Upstream 100 bases:

>100_bases
GGTCGGCTTACGTAGTGAGCGTCCGTGCCATACACCCAAGCTGAACCCCCCGGGTCGGCCGGTCTACCCGGCCGTAAAAA
GCTGGCGGGGGAATACGGAC

Downstream 100 bases:

>100_bases
TGTTGCGCGTGAGCCCGTCAGAAGGAGCTCGAAGAGTTTGGCGAGCGATCAAGACCGAACTGTCGGAGCACGGGCCCGAG
CTCGGCAGGTTGGAGGAAGA

Product: hydrogenase maturation factor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 332; Mature: 331

Protein sequence:

>332_residues
MSKVRREHGAGGELMESLIKEELLPNLTMRGEGSVTLDDLDDGATFPSVDGEMVMTTDAHIVDPPFFPGGNVGKLAAAGT
ANDLAVMGAKPVAFACSIVVREGFPIDDLKRVYRSIDGVLSELGAHLITGDTKVGNTGDVDIVVTMTGVGEIVELVRDCG
LRPGDKIVITGTVGDHGMAILAAQQGLDTDLESDVAPVWEAVNAALEVGGVTSMKDPTRGGLAGALNEMAEKSGVRIVIE
EERIPIREEVRVLSEMLGVNPLEVANEGKVVMGVRPDMVDDVLDAIRSTEVGKNAEVIGVVEEGTPRVEMETEVGGRRIV
EKPVGDPVPRVC

Sequences:

>Translated_332_residues
MSKVRREHGAGGELMESLIKEELLPNLTMRGEGSVTLDDLDDGATFPSVDGEMVMTTDAHIVDPPFFPGGNVGKLAAAGT
ANDLAVMGAKPVAFACSIVVREGFPIDDLKRVYRSIDGVLSELGAHLITGDTKVGNTGDVDIVVTMTGVGEIVELVRDCG
LRPGDKIVITGTVGDHGMAILAAQQGLDTDLESDVAPVWEAVNAALEVGGVTSMKDPTRGGLAGALNEMAEKSGVRIVIE
EERIPIREEVRVLSEMLGVNPLEVANEGKVVMGVRPDMVDDVLDAIRSTEVGKNAEVIGVVEEGTPRVEMETEVGGRRIV
EKPVGDPVPRVC
>Mature_331_residues
SKVRREHGAGGELMESLIKEELLPNLTMRGEGSVTLDDLDDGATFPSVDGEMVMTTDAHIVDPPFFPGGNVGKLAAAGTA
NDLAVMGAKPVAFACSIVVREGFPIDDLKRVYRSIDGVLSELGAHLITGDTKVGNTGDVDIVVTMTGVGEIVELVRDCGL
RPGDKIVITGTVGDHGMAILAAQQGLDTDLESDVAPVWEAVNAALEVGGVTSMKDPTRGGLAGALNEMAEKSGVRIVIEE
ERIPIREEVRVLSEMLGVNPLEVANEGKVVMGVRPDMVDDVLDAIRSTEVGKNAEVIGVVEEGTPRVEMETEVGGRRIVE
KPVGDPVPRVC

Specific function: Unknown

COG id: COG0309

COG function: function code O; Hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypE family [H]

Homologues:

Organism=Escherichia coli, GI226510967, Length=342, Percent_Identity=35.672514619883, Blast_Score=201, Evalue=4e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR011854
- InterPro:   IPR016188 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: NA

Molecular weight: Translated: 34969; Mature: 34838

Theoretical pI: Translated: 4.20; Mature: 4.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKVRREHGAGGELMESLIKEELLPNLTMRGEGSVTLDDLDDGATFPSVDGEMVMTTDAH
CCCCCHHCCCCHHHHHHHHHHHHCCCCEECCCCCEEECCCCCCCCCCCCCCCEEEEECCE
IVDPPFFPGGNVGKLAAAGTANDLAVMGAKPVAFACSIVVREGFPIDDLKRVYRSIDGVL
EECCCCCCCCCCCCEEECCCCCCEEEECCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
SELGAHLITGDTKVGNTGDVDIVVTMTGVGEIVELVRDCGLRPGDKIVITGTVGDHGMAI
HHHCCEEEECCCCCCCCCCEEEEEEECCHHHHHHHHHHCCCCCCCEEEEEECCCCCCEEE
LAAQQGLDTDLESDVAPVWEAVNAALEVGGVTSMKDPTRGGLAGALNEMAEKSGVRIVIE
EEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEE
EERIPIREEVRVLSEMLGVNPLEVANEGKVVMGVRPDMVDDVLDAIRSTEVGKNAEVIGV
CCCCCHHHHHHHHHHHHCCCCHHCCCCCCEEEECCCHHHHHHHHHHHHHCCCCCCEEEEE
VEEGTPRVEMETEVGGRRIVEKPVGDPVPRVC
EECCCCCEEEECCCCCCEEHHCCCCCCCCCCC
>Mature Secondary Structure 
SKVRREHGAGGELMESLIKEELLPNLTMRGEGSVTLDDLDDGATFPSVDGEMVMTTDAH
CCCCHHCCCCHHHHHHHHHHHHCCCCEECCCCCEEECCCCCCCCCCCCCCCEEEEECCE
IVDPPFFPGGNVGKLAAAGTANDLAVMGAKPVAFACSIVVREGFPIDDLKRVYRSIDGVL
EECCCCCCCCCCCCEEECCCCCCEEEECCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
SELGAHLITGDTKVGNTGDVDIVVTMTGVGEIVELVRDCGLRPGDKIVITGTVGDHGMAI
HHHCCEEEECCCCCCCCCCEEEEEEECCHHHHHHHHHHCCCCCCCEEEEEECCCCCCEEE
LAAQQGLDTDLESDVAPVWEAVNAALEVGGVTSMKDPTRGGLAGALNEMAEKSGVRIVIE
EEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEE
EERIPIREEVRVLSEMLGVNPLEVANEGKVVMGVRPDMVDDVLDAIRSTEVGKNAEVIGV
CCCCCHHHHHHHHHHHHCCCCHHCCCCCCEEEECCCHHHHHHHHHHHHHCCCCCCEEEEE
VEEGTPRVEMETEVGGRRIVEKPVGDPVPRVC
EECCCCCEEEECCCCCCEEHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]