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The map label for this gene is MenG [H]

Identifier: 20094885

GI number: 20094885

Start: 1479700

End: 1480290

Strand: Direct

Name: MenG [H]

Synonym: MK1449

Alternate gene names: 20094885

Gene position: 1479700-1480290 (Clockwise)

Preceding gene: 20094884

Following gene: 20094886

Centisome position: 87.3

GC content: 61.93

Gene sequence:

>591_bases
TTGGAAGTACCACCTTCTCCCGTCCTGAGCGATGCCTTAGGGAAGCGCTACGTACTCCGGGGAATCCGTCACATCGTGGG
CCCGGTGCCGATCTGCGGACGGGCGGTGACTGTGCTCGTGGAAGGGACGGACTGGGGGACCGTGGTGGAAGCCATCGACG
AGGCCGAGGAAGGTGACGTGCTCGTGATCCAAGCCAGAGACAGGGCGCGGGCGTACTGGGGAGGTCTCTCCTCTCTATCG
GCCAAGCGGAAGGGATTGGCCGGAACTGTCGTGGACGGATTAGTTAGGGACGTAGATGACGTACGCGAGATCGGCTACAC
CGTTTTCGCCCGCGGCGTTACCCCTAGAGCGGGAACCCACCGTCGATCCGGAAAGATTAACGTCGACCTGTACGTCTCGG
GCGTGCTCGTGCGTCCCGGTGACATTATAGTGGGGGACGAGAGCGGCGTCGTGGTCGTTCCCGAGGAGGAGTGGGAAGAC
GCGCTCAAGCGAGCCCGTGAGATACTCGAATTGGAAGATGACATCAGGACCGACATCGCGGCCAACCGTGCATGGTGGGA
GATCGTGCCGGATAAGTTGGGGGGATGGTGA

Upstream 100 bases:

>100_bases
ACCCGAGACAAGGAGCTCAAAAAGCGCCTGTGGAAACTCGGTGTTCCGGTGATAACGTTGCGTCAGCGCACACACCTGGT
GATCGAGCGGGGTTAACACC

Downstream 100 bases:

>100_bases
AGAGATGATGAACCTCTGGAAAGACCTGGAACCGGGCCCGAATCCACCCGACGTAGTGTACGCGGTGATAGAAATCCCAC
GTGGCTCGAGGAACAAGTAC

Product: demethylmenaquinone methyltransferase

Products: NA

Alternate protein names: HPS; D-arabino-3-hexulose-6-phosphate formaldehyde lyase [H]

Number of amino acids: Translated: 196; Mature: 196

Protein sequence:

>196_residues
MEVPPSPVLSDALGKRYVLRGIRHIVGPVPICGRAVTVLVEGTDWGTVVEAIDEAEEGDVLVIQARDRARAYWGGLSSLS
AKRKGLAGTVVDGLVRDVDDVREIGYTVFARGVTPRAGTHRRSGKINVDLYVSGVLVRPGDIIVGDESGVVVVPEEEWED
ALKRAREILELEDDIRTDIAANRAWWEIVPDKLGGW

Sequences:

>Translated_196_residues
MEVPPSPVLSDALGKRYVLRGIRHIVGPVPICGRAVTVLVEGTDWGTVVEAIDEAEEGDVLVIQARDRARAYWGGLSSLS
AKRKGLAGTVVDGLVRDVDDVREIGYTVFARGVTPRAGTHRRSGKINVDLYVSGVLVRPGDIIVGDESGVVVVPEEEWED
ALKRAREILELEDDIRTDIAANRAWWEIVPDKLGGW
>Mature_196_residues
MEVPPSPVLSDALGKRYVLRGIRHIVGPVPICGRAVTVLVEGTDWGTVVEAIDEAEEGDVLVIQARDRARAYWGGLSSLS
AKRKGLAGTVVDGLVRDVDDVREIGYTVFARGVTPRAGTHRRSGKINVDLYVSGVLVRPGDIIVGDESGVVVVPEEEWED
ALKRAREILELEDDIRTDIAANRAWWEIVPDKLGGW

Specific function: Catalyzes the condensation of ribulose 5-phosphate with formaldehyde to form 3-hexulose 6-phosphate [H]

COG id: COG0684

COG function: function code H; Demethylmenaquinone methyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HPS/KGPDC family. HPS subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR017120
- InterPro:   IPR001754
- InterPro:   IPR011060
- InterPro:   IPR005493 [H]

Pfam domain/function: PF03737 Methyltransf_6; PF00215 OMPdecase [H]

EC number: =4.1.2.43 [H]

Molecular weight: Translated: 21375; Mature: 21375

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEVPPSPVLSDALGKRYVLRGIRHIVGPVPICGRAVTVLVEGTDWGTVVEAIDEAEEGDV
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCHHHHHHHHHCCCCCCE
LVIQARDRARAYWGGLSSLSAKRKGLAGTVVDGLVRDVDDVREIGYTVFARGVTPRAGTH
EEEEECCHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCC
RRSGKINVDLYVSGVLVRPGDIIVGDESGVVVVPEEEWEDALKRAREILELEDDIRTDIA
CCCCEEEEEEEEEEEEECCCCEEEECCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHH
ANRAWWEIVPDKLGGW
CCCHHEEECCHHCCCC
>Mature Secondary Structure
MEVPPSPVLSDALGKRYVLRGIRHIVGPVPICGRAVTVLVEGTDWGTVVEAIDEAEEGDV
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCHHHHHHHHHCCCCCCE
LVIQARDRARAYWGGLSSLSAKRKGLAGTVVDGLVRDVDDVREIGYTVFARGVTPRAGTH
EEEEECCHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCC
RRSGKINVDLYVSGVLVRPGDIIVGDESGVVVVPEEEWEDALKRAREILELEDDIRTDIA
CCCCEEEEEEEEEEEEECCCCEEEECCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHH
ANRAWWEIVPDKLGGW
CCCHHEEECCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA