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The map label for this gene is 20094149

Identifier: 20094149

GI number: 20094149

Start: 677717

End: 678481

Strand: Reverse

Name: 20094149

Synonym: MK0712

Alternate gene names: NA

Gene position: 678481-677717 (Counterclockwise)

Preceding gene: 20094150

Following gene: 20094148

Centisome position: 40.03

GC content: 65.75

Gene sequence:

>765_bases
GTGAAGATACCACCCGATCACCCCAGGGCGGAGGCGTTGAAGATCCGTGAGCGCCTCGTGCGGGGGTTCGAGGACGGCTA
CGTGGTGCCTCAAGGACTGATCGCCCAGGGCAGGGGCGAGGTGTTCGACTACCTGATCGGCGAGAAGACGATTCCACCCG
CACGGGAGGCGATCAAGGCGGCGGCAGCCGCGTTCAAGCTCGCCGAACACCCAGTGATATCGGTGAACGGGAACACCGCC
GCCCTATGCCCGGAGGACCTCGTAGAGCTCTCCGAGGTCACGGGCGCTCCGCTGGAGGTGAACCTATTCCACCGGACGGA
AGATCGCGTGGAGAAGATAGCCGAGACCCTGAGGGAAGCCGGTGCCGACAGGGTGTTAGGCGCCGACCCGGAGCACCTTG
TCAGGCTCCCGAACCTGTCCTCGCATCGGGCCGTGGTCGACGATCGTGGGATCTATCGGGCGGACGTGGTCCTGGTACCC
CTGGAGGACGGGGACCGGACCCGCGCCCTGAAGGAGCTCGGGAAGACCGTCGTGGCCATCGACCTGAACCCGCTCTCCCG
CACGGCCCGTGATGCCGATATCACCATCGTTGACAACGTCGTACGCTGCGTCCGAAAGATCACGCGGGAGTACGAGCGGA
TGGACCCGGATCGTGCGAAGGGTGTGCTCCGGGAGTACGATAACGGGCGCGTGCTGGCCCGGGTTCTGGACCACATCCGA
GAGCGGCTGCGGGTGTTGGCCGATGAGGCTGCTGGTGCGACCTGA

Upstream 100 bases:

>100_bases
ACGGAGACGGCGAGGTCATCGAGCGGGTGAAAGGGGACAAGCGGGAGCTGGCCAGGAAGTTGGTAGACGCTCTCTCGAAA
CTGCTCCGGGGTGACCGCGG

Downstream 100 bases:

>100_bases
AGAGGAAGAGCTGGAACGCGTCCTACGCAGGTCGGAGATGGACGTGACGGAGGTCCTACCCGACGTCGAGCGGATCTTCG
AGGACGTAGTCGAACGCGGT

Product: hypothetical protein

Products: NA

Alternate protein names: PS; Pantoate--beta-alanine ligase; Pantoate-activating enzyme [H]

Number of amino acids: Translated: 254; Mature: 254

Protein sequence:

>254_residues
MKIPPDHPRAEALKIRERLVRGFEDGYVVPQGLIAQGRGEVFDYLIGEKTIPPAREAIKAAAAAFKLAEHPVISVNGNTA
ALCPEDLVELSEVTGAPLEVNLFHRTEDRVEKIAETLREAGADRVLGADPEHLVRLPNLSSHRAVVDDRGIYRADVVLVP
LEDGDRTRALKELGKTVVAIDLNPLSRTARDADITIVDNVVRCVRKITREYERMDPDRAKGVLREYDNGRVLARVLDHIR
ERLRVLADEAAGAT

Sequences:

>Translated_254_residues
MKIPPDHPRAEALKIRERLVRGFEDGYVVPQGLIAQGRGEVFDYLIGEKTIPPAREAIKAAAAAFKLAEHPVISVNGNTA
ALCPEDLVELSEVTGAPLEVNLFHRTEDRVEKIAETLREAGADRVLGADPEHLVRLPNLSSHRAVVDDRGIYRADVVLVP
LEDGDRTRALKELGKTVVAIDLNPLSRTARDADITIVDNVVRCVRKITREYERMDPDRAKGVLREYDNGRVLARVLDHIR
ERLRVLADEAAGAT
>Mature_254_residues
MKIPPDHPRAEALKIRERLVRGFEDGYVVPQGLIAQGRGEVFDYLIGEKTIPPAREAIKAAAAAFKLAEHPVISVNGNTA
ALCPEDLVELSEVTGAPLEVNLFHRTEDRVEKIAETLREAGADRVLGADPEHLVRLPNLSSHRAVVDDRGIYRADVVLVP
LEDGDRTRALKELGKTVVAIDLNPLSRTARDADITIVDNVVRCVRKITREYERMDPDRAKGVLREYDNGRVLARVLDHIR
ERLRVLADEAAGAT

Specific function: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent and ADP-producing reaction [H]

COG id: COG1701

COG function: function code S; Uncharacterized protein conserved in archaea

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the archaeal pantothenate synthetase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002855
- ProDom:   PD016827 [H]

Pfam domain/function: PF02006 DUF137 [H]

EC number: NA

Molecular weight: Translated: 28122; Mature: 28122

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIPPDHPRAEALKIRERLVRGFEDGYVVPQGLIAQGRGEVFDYLIGEKTIPPAREAIKA
CCCCCCCCHHHHHHHHHHHHHCCCCCEECCCHHHHCCCHHHHHHHHCCCCCCHHHHHHHH
AAAAFKLAEHPVISVNGNTAALCPEDLVELSEVTGAPLEVNLFHRTEDRVEKIAETLREA
HHHHHHHHCCCEEEECCCEEEECHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHC
GADRVLGADPEHLVRLPNLSSHRAVVDDRGIYRADVVLVPLEDGDRTRALKELGKTVVAI
CCCCCCCCCHHHHEECCCCCCCCEECCCCCCEEEEEEEEECCCCCHHHHHHHHCCEEEEE
DLNPLSRTARDADITIVDNVVRCVRKITREYERMDPDRAKGVLREYDNGRVLARVLDHIR
ECCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHH
ERLRVLADEAAGAT
HHHHHHHHHCCCCC
>Mature Secondary Structure
MKIPPDHPRAEALKIRERLVRGFEDGYVVPQGLIAQGRGEVFDYLIGEKTIPPAREAIKA
CCCCCCCCHHHHHHHHHHHHHCCCCCEECCCHHHHCCCHHHHHHHHCCCCCCHHHHHHHH
AAAAFKLAEHPVISVNGNTAALCPEDLVELSEVTGAPLEVNLFHRTEDRVEKIAETLREA
HHHHHHHHCCCEEEECCCEEEECHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHC
GADRVLGADPEHLVRLPNLSSHRAVVDDRGIYRADVVLVPLEDGDRTRALKELGKTVVAI
CCCCCCCCCHHHHEECCCCCCCCEECCCCCCEEEEEEEEECCCCCHHHHHHHHCCEEEEE
DLNPLSRTARDADITIVDNVVRCVRKITREYERMDPDRAKGVLREYDNGRVLARVLDHIR
ECCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHH
ERLRVLADEAAGAT
HHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12125824 [H]