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The map label for this gene is 20093634

Identifier: 20093634

GI number: 20093634

Start: 188360

End: 189619

Strand: Reverse

Name: 20093634

Synonym: MK0194

Alternate gene names: NA

Gene position: 189619-188360 (Counterclockwise)

Preceding gene: 20093635

Following gene: 20093633

Centisome position: 11.19

GC content: 60.63

Gene sequence:

>1260_bases
ATGGGCCGGATCATCAGGATACCAGTCCACGGATTCGTCGAGCTACAGGGGGCTGAGGAGCGCGTACTGGACTCACCCGA
AGTCCAACGGTTGAGGAGAGTCCGGCAGTTGGGTCTCGCGGAGCTGGTATACCCTGGCGCCACCCACACGAGGCTCGAAC
ATAGCTTGGGCGTGAAGTACCTGTGTGACCGCGTGATGGAGATTCACTGGGAAGAGCTCAAGCGTAACGTGCCGGACGTC
GGTAAGTTCTCGAGATCCTACATCGAGGAGGTGCTAGGGCTGGCCGGTCTGTTGCATGATGTGGGGCATCCGCCCTTTTC
GCATGTCCCGGAACCGCTGTTGGAGGAGGAGCTCGGGGTCGATCACGAGGACATCGGTCGTGCCGTAGCTAAGGTCGTGC
TGGAGAGGGCCGACGCCATGGACGTCGAGGTTACCTTGGAAGTGGCGTTCGGACCCGGCGATGGATGGACTGGCGTACTC
CACTCCGTGATCGCCGGGAACCTCGGTGTAGACCGCCTGGACTACCTCATGCGTGATTCCCTTCACGCCAGCGTGGAGTA
CGGCCGCATCGAACTCGACAGGCTCCTGCACACCCTGGAGTTGGGTGATCCCGTGGTCGTACATGAGAAGGGGTTGGAAG
CGGCGGAGTCCGTGCTGATATCCCGCTACCACATGTACAGGGCGGTGTATTTCCACAAGACATGCCGTGCCGGCGACGCG
ATGTTACTCTGGGCGATGCACGTTGCCGCCGAGGACGGCGACCTGGACCTCCGTATATTCGACCCGGATCGGCTGAGTCG
AAGCGAAGACGCACTATCCGCGTTTCAAAGCATGGACGACTCCGCCCTACTACGCGCGTTGGAGGAGAACCCCGAGAGCC
GTGAATTCGTGGAGGTCCTGAAGAACCGGCGCTTGTACAAGTGTGTGGCCGAGTACCAGGCGGCCGTGGAACCGAGACAT
GGTGAGCTCTTCAAGGTAGCCGTGGAGACCTCCGAGGAACACCTGGGAGAATCCTTCGGAGTGCTGTTGGATTCCTCGAA
GGTGGTTCCTTACGATCCCTCTTCCGACGAGGTGATCGTGAGGACGCGTAATGGTGATGTCCCGCTATCCGAGGTTTCCG
ACATCGTGGCGACGCTGAAGGAGCGCACGCTCTCCGAGATACCCACCGTTAGGGTGTACGTGCGTCCGGAGACGAGAGAC
GACGAGTCCCGCGTTCGGAGAATCGTGGAACACGTGAAGTCGGCGCTACCTCCAGCCTAG

Upstream 100 bases:

>100_bases
GCCTGCAAAAGGGCTCTGGAAGTCGTCAAGAGGACGATTTGGAGTGAGGAGTACCAGTGGGCCGTCGAGAAAGTCGAACG
AGAGCTACGGGGGAAAGAGG

Downstream 100 bases:

>100_bases
GATAACGTTATGGGGGTTATAACGAACGACCGCGGCCGCCGCGGGGAATTGAACCCCGCGCCCCACTCGGGGCGCGCCGG
ATCTGAAGTCCGGCCCGGGG

Product: HD superfamily phosphohydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 419; Mature: 418

Protein sequence:

>419_residues
MGRIIRIPVHGFVELQGAEERVLDSPEVQRLRRVRQLGLAELVYPGATHTRLEHSLGVKYLCDRVMEIHWEELKRNVPDV
GKFSRSYIEEVLGLAGLLHDVGHPPFSHVPEPLLEEELGVDHEDIGRAVAKVVLERADAMDVEVTLEVAFGPGDGWTGVL
HSVIAGNLGVDRLDYLMRDSLHASVEYGRIELDRLLHTLELGDPVVVHEKGLEAAESVLISRYHMYRAVYFHKTCRAGDA
MLLWAMHVAAEDGDLDLRIFDPDRLSRSEDALSAFQSMDDSALLRALEENPESREFVEVLKNRRLYKCVAEYQAAVEPRH
GELFKVAVETSEEHLGESFGVLLDSSKVVPYDPSSDEVIVRTRNGDVPLSEVSDIVATLKERTLSEIPTVRVYVRPETRD
DESRVRRIVEHVKSALPPA

Sequences:

>Translated_419_residues
MGRIIRIPVHGFVELQGAEERVLDSPEVQRLRRVRQLGLAELVYPGATHTRLEHSLGVKYLCDRVMEIHWEELKRNVPDV
GKFSRSYIEEVLGLAGLLHDVGHPPFSHVPEPLLEEELGVDHEDIGRAVAKVVLERADAMDVEVTLEVAFGPGDGWTGVL
HSVIAGNLGVDRLDYLMRDSLHASVEYGRIELDRLLHTLELGDPVVVHEKGLEAAESVLISRYHMYRAVYFHKTCRAGDA
MLLWAMHVAAEDGDLDLRIFDPDRLSRSEDALSAFQSMDDSALLRALEENPESREFVEVLKNRRLYKCVAEYQAAVEPRH
GELFKVAVETSEEHLGESFGVLLDSSKVVPYDPSSDEVIVRTRNGDVPLSEVSDIVATLKERTLSEIPTVRVYVRPETRD
DESRVRRIVEHVKSALPPA
>Mature_418_residues
GRIIRIPVHGFVELQGAEERVLDSPEVQRLRRVRQLGLAELVYPGATHTRLEHSLGVKYLCDRVMEIHWEELKRNVPDVG
KFSRSYIEEVLGLAGLLHDVGHPPFSHVPEPLLEEELGVDHEDIGRAVAKVVLERADAMDVEVTLEVAFGPGDGWTGVLH
SVIAGNLGVDRLDYLMRDSLHASVEYGRIELDRLLHTLELGDPVVVHEKGLEAAESVLISRYHMYRAVYFHKTCRAGDAM
LLWAMHVAAEDGDLDLRIFDPDRLSRSEDALSAFQSMDDSALLRALEENPESREFVEVLKNRRLYKCVAEYQAAVEPRHG
ELFKVAVETSEEHLGESFGVLLDSSKVVPYDPSSDEVIVRTRNGDVPLSEVSDIVATLKERTLSEIPTVRVYVRPETRDD
ESRVRRIVEHVKSALPPA

Specific function: Unknown

COG id: COG1078

COG function: function code R; HD superfamily phosphohydrolases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HD domain [H]

Homologues:

Organism=Homo sapiens, GI38016914, Length=353, Percent_Identity=26.628895184136, Blast_Score=107, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17537829, Length=382, Percent_Identity=25.130890052356, Blast_Score=79, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17537827, Length=382, Percent_Identity=25.130890052356, Blast_Score=78, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24666702, Length=200, Percent_Identity=29, Blast_Score=65, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003607
- InterPro:   IPR006675
- InterPro:   IPR011991 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 47133; Mature: 47002

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRIIRIPVHGFVELQGAEERVLDSPEVQRLRRVRQLGLAELVYPGATHTRLEHSLGVKY
CCCEEEECCCCEEEECCCHHHHCCCHHHHHHHHHHHCCHHHHHCCCCCHHHHHHHCCHHH
LCDRVMEIHWEELKRNVPDVGKFSRSYIEEVLGLAGLLHDVGHPPFSHVPEPLLEEELGV
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCHHHHHHHCC
DHEDIGRAVAKVVLERADAMDVEVTLEVAFGPGDGWTGVLHSVIAGNLGVDRLDYLMRDS
CHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHHH
LHASVEYGRIELDRLLHTLELGDPVVVHEKGLEAAESVLISRYHMYRAVYFHKTCRAGDA
HHHHHHCCHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
MLLWAMHVAAEDGDLDLRIFDPDRLSRSEDALSAFQSMDDSALLRALEENPESREFVEVL
HHHHHHHHHCCCCCEEEEEECHHHCCCCHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHH
KNRRLYKCVAEYQAAVEPRHGELFKVAVETSEEHLGESFGVLLDSSKVVPYDPSSDEVIV
HCCHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHCCCHHCEEEECCEECCCCCCCCCEEE
RTRNGDVPLSEVSDIVATLKERTLSEIPTVRVYVRPETRDDESRVRRIVEHVKSALPPA
EECCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
GRIIRIPVHGFVELQGAEERVLDSPEVQRLRRVRQLGLAELVYPGATHTRLEHSLGVKY
CCEEEECCCCEEEECCCHHHHCCCHHHHHHHHHHHCCHHHHHCCCCCHHHHHHHCCHHH
LCDRVMEIHWEELKRNVPDVGKFSRSYIEEVLGLAGLLHDVGHPPFSHVPEPLLEEELGV
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCHHHHHHHCC
DHEDIGRAVAKVVLERADAMDVEVTLEVAFGPGDGWTGVLHSVIAGNLGVDRLDYLMRDS
CHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHHH
LHASVEYGRIELDRLLHTLELGDPVVVHEKGLEAAESVLISRYHMYRAVYFHKTCRAGDA
HHHHHHCCHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
MLLWAMHVAAEDGDLDLRIFDPDRLSRSEDALSAFQSMDDSALLRALEENPESREFVEVL
HHHHHHHHHCCCCCEEEEEECHHHCCCCHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHH
KNRRLYKCVAEYQAAVEPRHGELFKVAVETSEEHLGESFGVLLDSSKVVPYDPSSDEVIV
HCCHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHCCCHHCEEEECCEECCCCCCCCCEEE
RTRNGDVPLSEVSDIVATLKERTLSEIPTVRVYVRPETRDDESRVRRIVEHVKSALPPA
EECCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]