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The map label for this gene is 20093517

Identifier: 20093517

GI number: 20093517

Start: 71931

End: 73088

Strand: Direct

Name: 20093517

Synonym: MK0077

Alternate gene names: NA

Gene position: 71931-73088 (Clockwise)

Preceding gene: 20093516

Following gene: 20093518

Centisome position: 4.24

GC content: 59.15

Gene sequence:

>1158_bases
CTGGAGCTAGTCCTGGGAACCGGTGCCGGCTACTCGGTCGAAGAGGACGGCGTCGAAATACCATCGGACTGGAAAGAGTT
GGCCGAGGAGCTGGCCGATCACGGTGGAACGCCGGTTTGCATGGTGATCGGTCCTCAGGACTCCGGCAAGACGACGCTAG
TTACCTTCATCGCCAACGAGCTCGTGGAGCGCGGGCTCAAGGTAGGTATCGTCGACGCCGATGTAGGGCAGTCGGATGTC
GGGCCTCCGGCGGTCGTCTCCTTAGGTATCGTCGAGGATACCGTCCACGACCTCTCCGAGGTAGAGATGAGACACGGGTA
CTTCGTCGGGTCGATCACCCCATCGGGTCACCTACTCCAGACCACCGTAGGGACTCGAAGGATGGTAGACCTCGCACTAG
CTGAAGGGACGGATGTCGTGCTCATCGATACCTCGGGGATGGTTCACGGCGGACCTGCTAGAGCCCTTAAACTCCACAAG
GTCGATGCGATCAGACCCTCACACGTGGCGTTCCTGGACCGTGACGGTCAGGTGTCACACATCAAGCGTATGGTGAAGTC
CTTGAAGTACATTAAGGTGCACGACCTCGCGGTGCCTGATGCCGTGAAGGACGTCGAACGGAAGGACCGTATTCGACGTA
GAGAGCGCGTACTGCGCGAGTTCTTCGAGGAACGGGAGATCCTGGAGCTCGACCTGGAGGAAGTCTCCGTACAGCGGGCG
TTTATAGGAACGGGTGAGCCGGTGGACTTGGAGGAGGAGAGTGAACTATCCGCACTGATCAAAGCGGTATCCGGTGTCGA
ACCCGAGATATTGCACGCGGAGAGAGCACCGGATGCCGTTGTTTTGGTCGTTAAAGACCAAGCCGGTCGAATCGTGGGAC
GCGGCGGCCGACATGCCCGAGAGCTTAGGCGGCTGCTTAACGTCCGAGAGTTCGTCGTAGTCAACGAGGAGGAACTTCAG
GGAGTGCTGGTAGGACTGTGTGACGGGGCCGGTGACCTGCTCGGTATCGGCGTGATTCGAGAGATCGACTTCGCCTCCGG
AGAACTGAAAGTCGAGGGCAGGTTACTCCGCGACAGGACGATTCGCGTCGTTCAGCTGGGCTCGCTTAAAGTGGACCCGG
AGACAGGGTCTCACGAGCCTATGAACGTACGAGTTTGA

Upstream 100 bases:

>100_bases
TGAAGCGACCACGAACAAAGGTACCGAAGTGAGTGAAGGCGAAGAACTCGTGATCAGGCGTGGGGAGCGACTGACGCTCA
CCACCGACTCGGAGCTCGAG

Downstream 100 bases:

>100_bases
CTCCAGTCCTGAAGGGTTAAGCTTTCGGGGCTGTGACGAGAATGTACGTGGGGATCGATCACGGTACCTCGGGGATCAAA
GTTGCAGCGTACGACGGTGA

Product: GTPase or GTP-binding protein

Products: NA

Alternate protein names: Polynucleotide kinase PF0112 [H]

Number of amino acids: Translated: 385; Mature: 385

Protein sequence:

>385_residues
MELVLGTGAGYSVEEDGVEIPSDWKELAEELADHGGTPVCMVIGPQDSGKTTLVTFIANELVERGLKVGIVDADVGQSDV
GPPAVVSLGIVEDTVHDLSEVEMRHGYFVGSITPSGHLLQTTVGTRRMVDLALAEGTDVVLIDTSGMVHGGPARALKLHK
VDAIRPSHVAFLDRDGQVSHIKRMVKSLKYIKVHDLAVPDAVKDVERKDRIRRRERVLREFFEEREILELDLEEVSVQRA
FIGTGEPVDLEEESELSALIKAVSGVEPEILHAERAPDAVVLVVKDQAGRIVGRGGRHARELRRLLNVREFVVVNEEELQ
GVLVGLCDGAGDLLGIGVIREIDFASGELKVEGRLLRDRTIRVVQLGSLKVDPETGSHEPMNVRV

Sequences:

>Translated_385_residues
MELVLGTGAGYSVEEDGVEIPSDWKELAEELADHGGTPVCMVIGPQDSGKTTLVTFIANELVERGLKVGIVDADVGQSDV
GPPAVVSLGIVEDTVHDLSEVEMRHGYFVGSITPSGHLLQTTVGTRRMVDLALAEGTDVVLIDTSGMVHGGPARALKLHK
VDAIRPSHVAFLDRDGQVSHIKRMVKSLKYIKVHDLAVPDAVKDVERKDRIRRRERVLREFFEEREILELDLEEVSVQRA
FIGTGEPVDLEEESELSALIKAVSGVEPEILHAERAPDAVVLVVKDQAGRIVGRGGRHARELRRLLNVREFVVVNEEELQ
GVLVGLCDGAGDLLGIGVIREIDFASGELKVEGRLLRDRTIRVVQLGSLKVDPETGSHEPMNVRV
>Mature_385_residues
MELVLGTGAGYSVEEDGVEIPSDWKELAEELADHGGTPVCMVIGPQDSGKTTLVTFIANELVERGLKVGIVDADVGQSDV
GPPAVVSLGIVEDTVHDLSEVEMRHGYFVGSITPSGHLLQTTVGTRRMVDLALAEGTDVVLIDTSGMVHGGPARALKLHK
VDAIRPSHVAFLDRDGQVSHIKRMVKSLKYIKVHDLAVPDAVKDVERKDRIRRRERVLREFFEEREILELDLEEVSVQRA
FIGTGEPVDLEEESELSALIKAVSGVEPEILHAERAPDAVVLVVKDQAGRIVGRGGRHARELRRLLNVREFVVVNEEELQ
GVLVGLCDGAGDLLGIGVIREIDFASGELKVEGRLLRDRTIRVVQLGSLKVDPETGSHEPMNVRV

Specific function: Polynucleotide kinase that can phosphorylate the 5'- hydroxyl groups of both single-stranded RNA (ssRNA) and single- stranded DNA (ssDNA). Exhibits a strong preference for ssRNA [H]

COG id: COG1341

COG function: function code R; Predicted GTPase or GTP-binding protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010655 [H]

Pfam domain/function: PF06807 Clp1 [H]

EC number: =2.7.1.78 [H]

Molecular weight: Translated: 41993; Mature: 41993

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELVLGTGAGYSVEEDGVEIPSDWKELAEELADHGGTPVCMVIGPQDSGKTTLVTFIANE
CEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEHHHHHHH
LVERGLKVGIVDADVGQSDVGPPAVVSLGIVEDTVHDLSEVEMRHGYFVGSITPSGHLLQ
HHHCCCEEEEEECCCCCCCCCCCCEEEECHHHHHHHHHHHHHHHCCEEEEEECCCCCEEE
TTVGTRRMVDLALAEGTDVVLIDTSGMVHGGPARALKLHKVDAIRPSHVAFLDRDGQVSH
ECCCCHHHHEEEEECCCCEEEEECCCCEECCCHHEEEEEEECCCCCCEEEEECCCCCHHH
IKRMVKSLKYIKVHDLAVPDAVKDVERKDRIRRRERVLREFFEEREILELDLEEVSVQRA
HHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEECHHHHHHHHH
FIGTGEPVDLEEESELSALIKAVSGVEPEILHAERAPDAVVLVVKDQAGRIVGRGGRHAR
CCCCCCCCCCCCHHHHHHHHHHHCCCCHHHEECCCCCCEEEEEEECCCCCEECCCCHHHH
ELRRLLNVREFVVVNEEELQGVLVGLCDGAGDLLGIGVIREIDFASGELKVEGRLLRDRT
HHHHHHCCHHEEEECHHHHCEEEEEEECCCCCHHHHHHHEEECCCCCEEEEEEEEECCCE
IRVVQLGSLKVDPETGSHEPMNVRV
EEEEEECCEEECCCCCCCCCCEEEC
>Mature Secondary Structure
MELVLGTGAGYSVEEDGVEIPSDWKELAEELADHGGTPVCMVIGPQDSGKTTLVTFIANE
CEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEHHHHHHH
LVERGLKVGIVDADVGQSDVGPPAVVSLGIVEDTVHDLSEVEMRHGYFVGSITPSGHLLQ
HHHCCCEEEEEECCCCCCCCCCCCEEEECHHHHHHHHHHHHHHHCCEEEEEECCCCCEEE
TTVGTRRMVDLALAEGTDVVLIDTSGMVHGGPARALKLHKVDAIRPSHVAFLDRDGQVSH
ECCCCHHHHEEEEECCCCEEEEECCCCEECCCHHEEEEEEECCCCCCEEEEECCCCCHHH
IKRMVKSLKYIKVHDLAVPDAVKDVERKDRIRRRERVLREFFEEREILELDLEEVSVQRA
HHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEECHHHHHHHHH
FIGTGEPVDLEEESELSALIKAVSGVEPEILHAERAPDAVVLVVKDQAGRIVGRGGRHAR
CCCCCCCCCCCCHHHHHHHHHHHCCCCHHHEECCCCCCEEEEEEECCCCCEECCCCHHHH
ELRRLLNVREFVVVNEEELQGVLVGLCDGAGDLLGIGVIREIDFASGELKVEGRLLRDRT
HHHHHHCCHHEEEECHHHHCEEEEEEECCCCCHHHHHHHEEECCCCCEEEEEEEEECCCE
IRVVQLGSLKVDPETGSHEPMNVRV
EEEEEECCEEECCCCCCCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA