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The map label for this gene is fhuG [H]

Identifier: 19745539

GI number: 19745539

Start: 358750

End: 359751

Strand: Reverse

Name: fhuG [H]

Synonym: spyM18_0436

Alternate gene names: 19745539

Gene position: 359751-358750 (Counterclockwise)

Preceding gene: 19745540

Following gene: 19745530

Centisome position: 18.98

GC content: 39.22

Gene sequence:

>1002_bases
TTGAAATCTCACCGACACCTTTTAAGGTTATATACTAGCCTGATCCTGCTACTTGTAAGTCTTATGGGATTAGCTTTGTC
CCTTGGAGAATCTCATCTATCTTTTTTGGACCTTGTCCATGTGTTTTTGGGAAAATCTAGCCATGCCATATCTTTCATCG
TTATTAACATTCGTCTGCCAAGAATTCTAGCTGCTTGTCTAGGAGGCGGTTCTCTTGCTTTATCAGGGCTATTATTACAA
CGTTTAACACGAAATCCCTTAGCTGACTCTGGTGTATTAGGTATTACTATAGGAGCAGGTATCCCTTTGGCTATTGTGGT
CTCCTTTTCTTTCTTTGAGCAAGCTCATATCAGCCATTACTTGCCTTTATTTGCCATGCTTGGTGCTGTTGTAACAACCT
TTAGCGTTTATTGGCTATCTTTGACAAAACAAGGACAAATTGATCCTACACGGTTAATTCTTACTGGTGTAGCTGTTACT
ACCATGCTTTCAAGTCTAATGGTTGCTCTTGTTGGTCATATTAATCGCTACAAAGTCGATTTGGTCATCAATTGGCTTAG
CGGCCAATTAATAGGAGACGACTGGCCTACTCTGAGTGTCATCGCTCCTTTATTATTGTGTTTTTGGCTATTGACTTATA
GTCAAGCCCATTTCCTTAATATTATGGGATTAGCTGATAATACTGCTATTGGGCTAGGACTCCCTTTAAACCGTAAGCGT
CGTTTGATACTTGTCTTAGCAGCTGGCTTAGGTGCTTTGAGTGTTCTTTTGGTTGGTAATATTAGTTTTATCGGCTTAAT
AGCTGGACACTTTAGTACATACTTGGTAGGGAGTAATCATAAAATAACAATACCCATTAGCATTTTAATCGGAATGATCC
TACTTCTTGTTGCAGATACAGTAGGACGAGTCTATCTGGTTGGCAGTAATATCCAGACAGGGATTTTAGTGTCGCTTATC
GGAGCCCCTTATTTTCTTTACTTAATGGCAAAAACAAAATAA

Upstream 100 bases:

>100_bases
GTCGTAATCTCAATCCGCCTTATGAAACCCCTCTTGGGGCATTGGTTAGCTTAATTGGTTTTCCATGCTTTTTATGGTTA
ATAAGAAGAGGAGGCCGCTA

Downstream 100 bases:

>100_bases
AAGCACTCAAAAAGCTAAGAACAGTCCTTGTTCCTAGCTTTTTTCTATGGTGCTATAAAGGTTAAACTTTCTTTATCCAA
GGTCATTAGCAGCTGGTATG

Product: ferrichrome ABC transporter permease

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: Ferric hydroxamate uptake protein G; Ferrichrome transport system permease protein fhuG; Iron(III)-hydroxamate import system permease protein fhuG [H]

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MKSHRHLLRLYTSLILLLVSLMGLALSLGESHLSFLDLVHVFLGKSSHAISFIVINIRLPRILAACLGGGSLALSGLLLQ
RLTRNPLADSGVLGITIGAGIPLAIVVSFSFFEQAHISHYLPLFAMLGAVVTTFSVYWLSLTKQGQIDPTRLILTGVAVT
TMLSSLMVALVGHINRYKVDLVINWLSGQLIGDDWPTLSVIAPLLLCFWLLTYSQAHFLNIMGLADNTAIGLGLPLNRKR
RLILVLAAGLGALSVLLVGNISFIGLIAGHFSTYLVGSNHKITIPISILIGMILLLVADTVGRVYLVGSNIQTGILVSLI
GAPYFLYLMAKTK

Sequences:

>Translated_333_residues
MKSHRHLLRLYTSLILLLVSLMGLALSLGESHLSFLDLVHVFLGKSSHAISFIVINIRLPRILAACLGGGSLALSGLLLQ
RLTRNPLADSGVLGITIGAGIPLAIVVSFSFFEQAHISHYLPLFAMLGAVVTTFSVYWLSLTKQGQIDPTRLILTGVAVT
TMLSSLMVALVGHINRYKVDLVINWLSGQLIGDDWPTLSVIAPLLLCFWLLTYSQAHFLNIMGLADNTAIGLGLPLNRKR
RLILVLAAGLGALSVLLVGNISFIGLIAGHFSTYLVGSNHKITIPISILIGMILLLVADTVGRVYLVGSNIQTGILVSLI
GAPYFLYLMAKTK
>Mature_333_residues
MKSHRHLLRLYTSLILLLVSLMGLALSLGESHLSFLDLVHVFLGKSSHAISFIVINIRLPRILAACLGGGSLALSGLLLQ
RLTRNPLADSGVLGITIGAGIPLAIVVSFSFFEQAHISHYLPLFAMLGAVVTTFSVYWLSLTKQGQIDPTRLILTGVAVT
TMLSSLMVALVGHINRYKVDLVINWLSGQLIGDDWPTLSVIAPLLLCFWLLTYSQAHFLNIMGLADNTAIGLGLPLNRKR
RLILVLAAGLGALSVLLVGNISFIGLIAGHFSTYLVGSNHKITIPISILIGMILLLVADTVGRVYLVGSNIQTGILVSLI
GAPYFLYLMAKTK

Specific function: Part of the ABC transporter complex fhuBGCD involved in iron(3+)-hydroxamate import. Responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790740, Length=290, Percent_Identity=32.7586206896552, Blast_Score=124, Evalue=7e-30,
Organism=Escherichia coli, GI1786805, Length=306, Percent_Identity=34.640522875817, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1786347, Length=310, Percent_Identity=32.258064516129, Blast_Score=105, Evalue=6e-24,
Organism=Escherichia coli, GI1788004, Length=286, Percent_Identity=32.1678321678322, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1790741, Length=285, Percent_Identity=32.280701754386, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1786804, Length=248, Percent_Identity=31.4516129032258, Blast_Score=92, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 35824; Mature: 35824

Theoretical pI: Translated: 10.25; Mature: 10.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSHRHLLRLYTSLILLLVSLMGLALSLGESHLSFLDLVHVFLGKSSHAISFIVINIRLP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCEEEEEEEEEEHH
RILAACLGGGSLALSGLLLQRLTRNPLADSGVLGITIGAGIPLAIVVSFSFFEQAHISHY
HHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHH
LPLFAMLGAVVTTFSVYWLSLTKQGQIDPTRLILTGVAVTTMLSSLMVALVGHINRYKVD
HHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
LVINWLSGQLIGDDWPTLSVIAPLLLCFWLLTYSQAHFLNIMGLADNTAIGLGLPLNRKR
EEEEECCCCEECCCCCHHHHHHHHHHHHHHHHHCHHHHEEEEECCCCCEEEECCCCCCCC
RLILVLAAGLGALSVLLVGNISFIGLIAGHFSTYLVGSNHKITIPISILIGMILLLVADT
EEEEEEECCHHHHHHHHHCCHHHHHHHHHHHHHEEECCCCEEEEEHHHHHHHHHHHHHHC
VGRVYLVGSNIQTGILVSLIGAPYFLYLMAKTK
CCEEEEECCCCCHHHHHHHHHCCCEEEEEEECC
>Mature Secondary Structure
MKSHRHLLRLYTSLILLLVSLMGLALSLGESHLSFLDLVHVFLGKSSHAISFIVINIRLP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCEEEEEEEEEEHH
RILAACLGGGSLALSGLLLQRLTRNPLADSGVLGITIGAGIPLAIVVSFSFFEQAHISHY
HHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHH
LPLFAMLGAVVTTFSVYWLSLTKQGQIDPTRLILTGVAVTTMLSSLMVALVGHINRYKVD
HHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
LVINWLSGQLIGDDWPTLSVIAPLLLCFWLLTYSQAHFLNIMGLADNTAIGLGLPLNRKR
EEEEECCCCEECCCCCHHHHHHHHHHHHHHHHHCHHHHEEEEECCCCCEEEECCCCCCCC
RLILVLAAGLGALSVLLVGNISFIGLIAGHFSTYLVGSNHKITIPISILIGMILLLVADT
EEEEEEECCHHHHHHHHHCCHHHHHHHHHHHHHEEECCCCEEEEEHHHHHHHHHHHHHHC
VGRVYLVGSNIQTGILVSLIGAPYFLYLMAKTK
CCEEEEECCCCCHHHHHHHHHCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9639930; 9384377 [H]