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The map label for this gene is dppA [H]

Identifier: 18977963

GI number: 18977963

Start: 1485067

End: 1485903

Strand: Direct

Name: dppA [H]

Synonym: PF1591

Alternate gene names: 18977963

Gene position: 1485067-1485903 (Clockwise)

Preceding gene: 18977962

Following gene: 18977964

Centisome position: 77.82

GC content: 42.53

Gene sequence:

>837_bases
ATGAAGGCCTTCATATCTATAGATTTAGAGGGGCTTCCCTACATCGTTAGTAGGGAGCATCTATTTGTAAAGGGAGCCCT
ATATAATGAGGCCCGAAAAATCGCCACAAAAATTGCAAAAATTGCTGCAGAAAAGTTACACGAGGAAGGATTTGAGGAGA
TAGTAATAGCAGATTCTCACGGCCCTATGGTGAATATAATACCTGAGGAAATGCCAAGTTATGTTTCCATAGTTAGAGGA
TTTCCCAGGCCTTTAAGTATGGTGGCATTTGGAAAAGGCTCAGATATTGCAATCTTCTTGGGTTACCATGCCAAAGCCGG
GACGAGTTTTGCAACCTTTGACCACACCTACAGTGGAGCCACAATTGACAAGATAATCATTAGCGGCATTGAAGTTAGTG
AGTTCCTTTTAAATTCCATGGTGCTCGGAGAGTGGGGAGTGCCAATAGGGCTTGTTGCAGGAGATGAGGCGTTAAAAGAA
GATTTAAAATACGTCCCCTGGGCTGAGTTTATCCCCCTCAAAAAGGCTAGTGGGAGGTATTCGGCCCTGAGCCCCTCTAT
GGAAGCAATAGAGAAAGAGCTAAAAGCAGGGATTAAGAGAGCTGTTGAAAAGTTAAACAACAAAGAGTTAAGGGCCTTTA
AAATAGAAACTCCAGTTGACGTTGAGATAAGATTCCTCAATAGTGCATATGCAGAAGTTGCAGATCTTCTCCCAGGTGTT
GAAAGAATAGATGGAAAAACAATTCGATTCACCGCAAACACTGTAGAGGATGCATACAAAATTATGGAGGTTTTGACATT
AGCTGCTGCAGGGGTTTCTTACATCGTGTCTAGATAG

Upstream 100 bases:

>100_bases
AAGCAAAGCTGGCTTTTGACCACGCTAAGATTATAGAAGATGCCTTAACGCTAAGATAAACATAAAAATGGACAGAGATA
ATTTATTTCGGTGAAATATC

Downstream 100 bases:

>100_bases
GTCTACCTATCCAAACTTTTATTATTTCTCTCCTTTTGGTTATTTCTTGATGTCTATGGGTGGTCGTTTTTGGTAGAATC
GTGAACTTGTTTCAACTGCA

Product: dipeptide transport protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 278; Mature: 278

Protein sequence:

>278_residues
MKAFISIDLEGLPYIVSREHLFVKGALYNEARKIATKIAKIAAEKLHEEGFEEIVIADSHGPMVNIIPEEMPSYVSIVRG
FPRPLSMVAFGKGSDIAIFLGYHAKAGTSFATFDHTYSGATIDKIIISGIEVSEFLLNSMVLGEWGVPIGLVAGDEALKE
DLKYVPWAEFIPLKKASGRYSALSPSMEAIEKELKAGIKRAVEKLNNKELRAFKIETPVDVEIRFLNSAYAEVADLLPGV
ERIDGKTIRFTANTVEDAYKIMEVLTLAAAGVSYIVSR

Sequences:

>Translated_278_residues
MKAFISIDLEGLPYIVSREHLFVKGALYNEARKIATKIAKIAAEKLHEEGFEEIVIADSHGPMVNIIPEEMPSYVSIVRG
FPRPLSMVAFGKGSDIAIFLGYHAKAGTSFATFDHTYSGATIDKIIISGIEVSEFLLNSMVLGEWGVPIGLVAGDEALKE
DLKYVPWAEFIPLKKASGRYSALSPSMEAIEKELKAGIKRAVEKLNNKELRAFKIETPVDVEIRFLNSAYAEVADLLPGV
ERIDGKTIRFTANTVEDAYKIMEVLTLAAAGVSYIVSR
>Mature_278_residues
MKAFISIDLEGLPYIVSREHLFVKGALYNEARKIATKIAKIAAEKLHEEGFEEIVIADSHGPMVNIIPEEMPSYVSIVRG
FPRPLSMVAFGKGSDIAIFLGYHAKAGTSFATFDHTYSGATIDKIIISGIEVSEFLLNSMVLGEWGVPIGLVAGDEALKE
DLKYVPWAEFIPLKKASGRYSALSPSMEAIEKELKAGIKRAVEKLNNKELRAFKIETPVDVEIRFLNSAYAEVADLLPGV
ERIDGKTIRFTANTVEDAYKIMEVLTLAAAGVSYIVSR

Specific function: Hydrolyzes N-terminal residues in D-amino acid containing peptides. Among the tested substrates, the highest activities are with D-Ala-D-Ala and D-Ala-Gly-Gly. The physiological role is not clear [H]

COG id: COG2362

COG function: function code E; D-aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M55 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007035 [H]

Pfam domain/function: PF04951 Peptidase_M55 [H]

EC number: NA

Molecular weight: Translated: 30529; Mature: 30529

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAFISIDLEGLPYIVSREHLFVKGALYNEARKIATKIAKIAAEKLHEEGFEEIVIADSH
CCEEEEEECCCCCEEEECCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCC
GPMVNIIPEEMPSYVSIVRGFPRPLSMVAFGKGSDIAIFLGYHAKAGTSFATFDHTYSGA
CCEEEECHHHHHHHHHHHHCCCCCCEEEEECCCCCEEEEEEECCCCCCEEEECCCCCCCC
TIDKIIISGIEVSEFLLNSMVLGEWGVPIGLVAGDEALKEDLKYVPWAEFIPLKKASGRY
HHHHHHHCCCHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHCCCCCHHHCCCCCCCCCC
SALSPSMEAIEKELKAGIKRAVEKLNNKELRAFKIETPVDVEIRFLNSAYAEVADLLPGV
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEHHHHHHHHHHHCCCH
ERIDGKTIRFTANTVEDAYKIMEVLTLAAAGVSYIVSR
HHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKAFISIDLEGLPYIVSREHLFVKGALYNEARKIATKIAKIAAEKLHEEGFEEIVIADSH
CCEEEEEECCCCCEEEECCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCC
GPMVNIIPEEMPSYVSIVRGFPRPLSMVAFGKGSDIAIFLGYHAKAGTSFATFDHTYSGA
CCEEEECHHHHHHHHHHHHCCCCCCEEEEECCCCCEEEEEEECCCCCCEEEECCCCCCCC
TIDKIIISGIEVSEFLLNSMVLGEWGVPIGLVAGDEALKEDLKYVPWAEFIPLKKASGRY
HHHHHHHCCCHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHCCCCCHHHCCCCCCCCCC
SALSPSMEAIEKELKAGIKRAVEKLNNKELRAFKIETPVDVEIRFLNSAYAEVADLLPGV
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEHHHHHHHHHHHCCCH
ERIDGKTIRFTANTVEDAYKIMEVLTLAAAGVSYIVSR
HHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1766370; 9384377 [H]