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The map label for this gene is yicO [C]

Identifier: 18977224

GI number: 18977224

Start: 825103

End: 826431

Strand: Reverse

Name: yicO [C]

Synonym: PF0852

Alternate gene names: 18977224

Gene position: 826431-825103 (Counterclockwise)

Preceding gene: 18977225

Following gene: 18977220

Centisome position: 43.31

GC content: 45.75

Gene sequence:

>1329_bases
ATGGGGTGGATTGAAAGGTATTTTGAGTTCGAAAAATATGGTACTGATTTGAAGACAGAAGTGTTGGCAGGAATTACAAC
CTTCATGACCATGGCCTACATAATCTTCGTAAATCCAATAATTCTCAGCAACGCAATGGGGCCAGAGGCCTTCGACTCTC
TAGTTGCAGCAACTTCACTCGCGGCAGGTTTAACAACAATCCTAATGGGTATATACGCAAAGAAGCCCTTCGCCCTCGCT
CCTGGGATGGGGCTTAACGCATACTTTGCATTTACAGTGGCCCCAAAGTATGGATGGAAGGTCGCTCTTGCAGCTGTATT
CGTTGAGGGTATTATCTTCATAATTCTAAGTATTACAAAGGTCAGAAGCGCGATAATCCATGCAATCCCACTGAGTCAAA
AGTACGCTGTTGGGGCTGGAATCGGACTGTTCTTGACGTTTATAGGACTTAACAACGTTGGATTGCTAACCGCTTTAACA
GGAGACAATGGATTGCTCATTAAGACATCACTAAATGCTTCCGTCTTGGCCAAACCAGAAGGACTATTATTCCTGTTTGG
GCTCTTCCTAACGGCGATCCTCTTATCCTTGAGAATCAAGGGAGCCCTGCTAATTTCCATCTTGGCAACGAGCATAATTG
GATGGATAACAGGGGTTGCCCCCAGGCCAGAGGGAGTATTCTCAATGCCAACACTAAGCTATACATTCCTCCAGCTTGAC
CTTAAGGGATTGCTTAACGCTGGAGCACTTGGAGCTGTATTCGCATTCTTCATGGTAGACTTCTTCGACACCCTGGGAAC
AGTTACGGGTCTTAGTGCCAAGGCTGGATTCCTAACAAAGGAGGGTAAGATTCCAGATGCTGAAAAGGTTCTCCTCACAG
ATGCCATTGGTACAACTTTTGGTGCAATTTTGGGAACTTCCACTGTAACAACATACATCGAGAGCGCAGCCGGTATTGAG
GAAGGAGGTAGAACAGGATTTACAGCAGTGATTACGGGACTTCTGTTCCTAATCATTGGACTCTTCATAGCTCCAGTGGC
CAAGGCAATTCCAGCCTTCGCAACAGCACCTGCCTTAGTTATAGTAGGTTACTACATGATTTCAGCATTCAAGGAAGTTG
ACTTTAGCGACCCAACAGAGGCAATTCCAGCCTTCCTAGTCCTCATAACGATTCCATTCACATACTCAATTGCCGACGGT
ATTGGAGTTGGATTCATAAGCTACACGTTACTAAAGGTCTTCACAGGAAGGTGGAAAGAAGTCCACCCACTAATGTATGC
ACTAGCGGTGGTATTCATAGGCTACTTCGCCTACTTAGCCACAGCTTGA

Upstream 100 bases:

>100_bases
CCAAAGAGTTACATCCGAGAAGTTTTATACACATTCATGTCTAAAAAAGCTTAAAAGGTTGTATCACTTTGACAAAACAA
AGGCAATTGGAGGGTAGGAG

Downstream 100 bases:

>100_bases
TCCTTTTCTCTAACTTTTTTTAAGAACTGCTTTAACGCATAGGGACATTCTTGCTGAATATAGCTTATGAATTCTCTAAT
CCTATGTACTGTAACCTCAC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 442; Mature: 441

Protein sequence:

>442_residues
MGWIERYFEFEKYGTDLKTEVLAGITTFMTMAYIIFVNPIILSNAMGPEAFDSLVAATSLAAGLTTILMGIYAKKPFALA
PGMGLNAYFAFTVAPKYGWKVALAAVFVEGIIFIILSITKVRSAIIHAIPLSQKYAVGAGIGLFLTFIGLNNVGLLTALT
GDNGLLIKTSLNASVLAKPEGLLFLFGLFLTAILLSLRIKGALLISILATSIIGWITGVAPRPEGVFSMPTLSYTFLQLD
LKGLLNAGALGAVFAFFMVDFFDTLGTVTGLSAKAGFLTKEGKIPDAEKVLLTDAIGTTFGAILGTSTVTTYIESAAGIE
EGGRTGFTAVITGLLFLIIGLFIAPVAKAIPAFATAPALVIVGYYMISAFKEVDFSDPTEAIPAFLVLITIPFTYSIADG
IGVGFISYTLLKVFTGRWKEVHPLMYALAVVFIGYFAYLATA

Sequences:

>Translated_442_residues
MGWIERYFEFEKYGTDLKTEVLAGITTFMTMAYIIFVNPIILSNAMGPEAFDSLVAATSLAAGLTTILMGIYAKKPFALA
PGMGLNAYFAFTVAPKYGWKVALAAVFVEGIIFIILSITKVRSAIIHAIPLSQKYAVGAGIGLFLTFIGLNNVGLLTALT
GDNGLLIKTSLNASVLAKPEGLLFLFGLFLTAILLSLRIKGALLISILATSIIGWITGVAPRPEGVFSMPTLSYTFLQLD
LKGLLNAGALGAVFAFFMVDFFDTLGTVTGLSAKAGFLTKEGKIPDAEKVLLTDAIGTTFGAILGTSTVTTYIESAAGIE
EGGRTGFTAVITGLLFLIIGLFIAPVAKAIPAFATAPALVIVGYYMISAFKEVDFSDPTEAIPAFLVLITIPFTYSIADG
IGVGFISYTLLKVFTGRWKEVHPLMYALAVVFIGYFAYLATA
>Mature_441_residues
GWIERYFEFEKYGTDLKTEVLAGITTFMTMAYIIFVNPIILSNAMGPEAFDSLVAATSLAAGLTTILMGIYAKKPFALAP
GMGLNAYFAFTVAPKYGWKVALAAVFVEGIIFIILSITKVRSAIIHAIPLSQKYAVGAGIGLFLTFIGLNNVGLLTALTG
DNGLLIKTSLNASVLAKPEGLLFLFGLFLTAILLSLRIKGALLISILATSIIGWITGVAPRPEGVFSMPTLSYTFLQLDL
KGLLNAGALGAVFAFFMVDFFDTLGTVTGLSAKAGFLTKEGKIPDAEKVLLTDAIGTTFGAILGTSTVTTYIESAAGIEE
GGRTGFTAVITGLLFLIIGLFIAPVAKAIPAFATAPALVIVGYYMISAFKEVDFSDPTEAIPAFLVLITIPFTYSIADGI
GVGFISYTLLKVFTGRWKEVHPLMYALAVVFIGYFAYLATA

Specific function: Unknown

COG id: COG2252

COG function: function code R; Permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. AzgA purine transporter (TC 2.A.1.40) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082309, Length=435, Percent_Identity=39.7701149425287, Blast_Score=308, Evalue=4e-85,
Organism=Escherichia coli, GI1790150, Length=437, Percent_Identity=40.045766590389, Blast_Score=305, Evalue=5e-84,
Organism=Escherichia coli, GI1790499, Length=448, Percent_Identity=35.0446428571429, Blast_Score=241, Evalue=6e-65,
Organism=Escherichia coli, GI48994909, Length=430, Percent_Identity=35.5813953488372, Blast_Score=219, Evalue=3e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 46872; Mature: 46741

Theoretical pI: Translated: 6.56; Mature: 6.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGWIERYFEFEKYGTDLKTEVLAGITTFMTMAYIIFVNPIILSNAMGPEAFDSLVAATSL
CCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
AAGLTTILMGIYAKKPFALAPGMGLNAYFAFTVAPKYGWKVALAAVFVEGIIFIILSITK
HHHHHHHHHHHHCCCCCEECCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
VRSAIIHAIPLSQKYAVGAGIGLFLTFIGLNNVGLLTALTGDNGLLIKTSLNASVLAKPE
HHHHHHHHCCCCCCHHHHCHHHHHHHHHCCCCCCEEEEEECCCCEEEEEECCCEEEECCC
GLLFLFGLFLTAILLSLRIKGALLISILATSIIGWITGVAPRPEGVFSMPTLSYTFLQLD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCHHHHHHHHH
LKGLLNAGALGAVFAFFMVDFFDTLGTVTGLSAKAGFLTKEGKIPDAEKVLLTDAIGTTF
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCCHHHHHHHHHHHHHH
GAILGTSTVTTYIESAAGIEEGGRTGFTAVITGLLFLIIGLFIAPVAKAIPAFATAPALV
HHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IVGYYMISAFKEVDFSDPTEAIPAFLVLITIPFTYSIADGIGVGFISYTLLKVFTGRWKE
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCHHHHHHCCHHHHHHHHHHHHHHHCCCHH
VHPLMYALAVVFIGYFAYLATA
HHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GWIERYFEFEKYGTDLKTEVLAGITTFMTMAYIIFVNPIILSNAMGPEAFDSLVAATSL
CHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
AAGLTTILMGIYAKKPFALAPGMGLNAYFAFTVAPKYGWKVALAAVFVEGIIFIILSITK
HHHHHHHHHHHHCCCCCEECCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
VRSAIIHAIPLSQKYAVGAGIGLFLTFIGLNNVGLLTALTGDNGLLIKTSLNASVLAKPE
HHHHHHHHCCCCCCHHHHCHHHHHHHHHCCCCCCEEEEEECCCCEEEEEECCCEEEECCC
GLLFLFGLFLTAILLSLRIKGALLISILATSIIGWITGVAPRPEGVFSMPTLSYTFLQLD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCHHHHHHHHH
LKGLLNAGALGAVFAFFMVDFFDTLGTVTGLSAKAGFLTKEGKIPDAEKVLLTDAIGTTF
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCCHHHHHHHHHHHHHH
GAILGTSTVTTYIESAAGIEEGGRTGFTAVITGLLFLIIGLFIAPVAKAIPAFATAPALV
HHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IVGYYMISAFKEVDFSDPTEAIPAFLVLITIPFTYSIADGIGVGFISYTLLKVFTGRWKE
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCHHHHHHCCHHHHHHHHHHHHHHHCCCHH
VHPLMYALAVVFIGYFAYLATA
HHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]