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The map label for this gene is appB [H]

Identifier: 18976563

GI number: 18976563

Start: 203712

End: 204761

Strand: Direct

Name: appB [H]

Synonym: PF0191

Alternate gene names: 18976563

Gene position: 203712-204761 (Clockwise)

Preceding gene: 18976562

Following gene: 18976564

Centisome position: 10.68

GC content: 40.86

Gene sequence:

>1050_bases
ATGGGGTTAGGTAAATATCTGCTCATAAGAGCTATAAACGCATTAATTGTGCTCTCTATAGTCGTTCTAGTAGTCTCAGC
ACTTTTCGTTAAAGTTGCAGAAAAAGAGCTGGAGAGTAGAATTCAGGAAATAGTGAATGCGGAATATCAATCTCTCGTGC
AACAAAATAGAGCTCCTTCAGATCCGGAAGCTTGGAAAATGGAAAGAATAAAGTATTACAGACACCTATATAAGTTAGAC
CAGCCCTATCATATAAGAGTCTTGTACTATGCTAAAAGAACGATAACTCTCGACTTTGGTAACACTAGAATTCCAATCTT
TGGAACCGAGAGAAATGTGAAGGCAATAATTTCTTTAGCACTCCCAAGAACGATACTGCTGTTTACAACGGCCCAGATTA
TAGTTATAATCTTGGGACTATTGCTTGGTGTCAAAGCTGCTCAAAAAGTCGGAAGTCTGTTTGACAGGGCACTTTCAGTT
CTTGCCCTAGTGACTACGAGTATTCCAATGTGGTGGTTTGGAATGATAATGCTTCTAATCTTTGCATTTAAGCTTGGATG
GTTCCCATCTAATTCAATGCCAAACCCCAATTTAACAGGATTAGACCATGTTCTGGACGTTGCTCGTAGGTTGGTTCTTC
CAATAACCACAATAGTATTCGTGCTCTTTGGAGGCTGGGCTTGGGTTACTAGAAATATTATGATAAGTACTCTTCAAGAG
GACTTCATCATGGTGGCCAGAGCAAAAGGTGTTCCAGAAAGGAAGGTGATCTATGGACATGGTTTGAGAGCCGCGGCACC
TCCAATAGTTACAATGACAATATTCTCGCTCTTAGGTTCCCTGGGTGGTGCCATAATTACGGAGAGTGTATTTAACTGGC
CTGGAATGGGAAGAGTTTATTGGATTGCTATCGAAACTCAGGAGATAAATCTAGTAATGGGACTAACCTTCATCAGCGTG
GTATTGTACCTTGCTGGAGTAATAATAGCTGACATCTCATATGGATTCCTAGATCCAAGAGTAAGAGTAGGTGCTTCAGC
AAAGATGTGA

Upstream 100 bases:

>100_bases
GTTTATCGAAATAAAATATTTAAAGTAGTTTTACAAGTTTGAAAAAGATGATGATCAAAAATGTTCGTTAGAAAACTGGA
GTGAGCAGGGGGATGGAAAA

Downstream 100 bases:

>100_bases
GGTGGTTGCAATGAGATGGGTAGACCTCAAAGAATCCCTCTCAGACTTTTGGTTTGAATTCAGAAGAGAGAAAACTGGAA
TTGCTGGACTAGCTCTACTT

Product: oligopeptide transport system permease protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 349; Mature: 348

Protein sequence:

>349_residues
MGLGKYLLIRAINALIVLSIVVLVVSALFVKVAEKELESRIQEIVNAEYQSLVQQNRAPSDPEAWKMERIKYYRHLYKLD
QPYHIRVLYYAKRTITLDFGNTRIPIFGTERNVKAIISLALPRTILLFTTAQIIVIILGLLLGVKAAQKVGSLFDRALSV
LALVTTSIPMWWFGMIMLLIFAFKLGWFPSNSMPNPNLTGLDHVLDVARRLVLPITTIVFVLFGGWAWVTRNIMISTLQE
DFIMVARAKGVPERKVIYGHGLRAAAPPIVTMTIFSLLGSLGGAIITESVFNWPGMGRVYWIAIETQEINLVMGLTFISV
VLYLAGVIIADISYGFLDPRVRVGASAKM

Sequences:

>Translated_349_residues
MGLGKYLLIRAINALIVLSIVVLVVSALFVKVAEKELESRIQEIVNAEYQSLVQQNRAPSDPEAWKMERIKYYRHLYKLD
QPYHIRVLYYAKRTITLDFGNTRIPIFGTERNVKAIISLALPRTILLFTTAQIIVIILGLLLGVKAAQKVGSLFDRALSV
LALVTTSIPMWWFGMIMLLIFAFKLGWFPSNSMPNPNLTGLDHVLDVARRLVLPITTIVFVLFGGWAWVTRNIMISTLQE
DFIMVARAKGVPERKVIYGHGLRAAAPPIVTMTIFSLLGSLGGAIITESVFNWPGMGRVYWIAIETQEINLVMGLTFISV
VLYLAGVIIADISYGFLDPRVRVGASAKM
>Mature_348_residues
GLGKYLLIRAINALIVLSIVVLVVSALFVKVAEKELESRIQEIVNAEYQSLVQQNRAPSDPEAWKMERIKYYRHLYKLDQ
PYHIRVLYYAKRTITLDFGNTRIPIFGTERNVKAIISLALPRTILLFTTAQIIVIILGLLLGVKAAQKVGSLFDRALSVL
ALVTTSIPMWWFGMIMLLIFAFKLGWFPSNSMPNPNLTGLDHVLDVARRLVLPITTIVFVLFGGWAWVTRNIMISTLQED
FIMVARAKGVPERKVIYGHGLRAAAPPIVTMTIFSLLGSLGGAIITESVFNWPGMGRVYWIAIETQEINLVMGLTFISVV
LYLAGVIIADISYGFLDPRVRVGASAKM

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787053, Length=286, Percent_Identity=28.6713286713287, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1789965, Length=287, Percent_Identity=29.616724738676, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1787497, Length=267, Percent_Identity=27.3408239700375, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1789888, Length=281, Percent_Identity=26.3345195729537, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1788504, Length=291, Percent_Identity=26.1168384879725, Blast_Score=95, Evalue=6e-21,
Organism=Escherichia coli, GI1787761, Length=294, Percent_Identity=27.5510204081633, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI1787550, Length=274, Percent_Identity=23.3576642335766, Blast_Score=68, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 39010; Mature: 38879

Theoretical pI: Translated: 10.31; Mature: 10.31

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLGKYLLIRAINALIVLSIVVLVVSALFVKVAEKELESRIQEIVNAEYQSLVQQNRAPS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
DPEAWKMERIKYYRHLYKLDQPYHIRVLYYAKRTITLDFGNTRIPIFGTERNVKAIISLA
CCHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEEEEEECCCEEEEEEECCCCHHHHHHHH
LPRTILLFTTAQIIVIILGLLLGVKAAQKVGSLFDRALSVLALVTTSIPMWWFGMIMLLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
FAFKLGWFPSNSMPNPNLTGLDHVLDVARRLVLPITTIVFVLFGGWAWVTRNIMISTLQE
HHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
DFIMVARAKGVPERKVIYGHGLRAAAPPIVTMTIFSLLGSLGGAIITESVFNWPGMGRVY
HHHHHHHCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHCCCCCCEEE
WIAIETQEINLVMGLTFISVVLYLAGVIIADISYGFLDPRVRVGASAKM
EEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
GLGKYLLIRAINALIVLSIVVLVVSALFVKVAEKELESRIQEIVNAEYQSLVQQNRAPS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
DPEAWKMERIKYYRHLYKLDQPYHIRVLYYAKRTITLDFGNTRIPIFGTERNVKAIISLA
CCHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEEEEEECCCEEEEEEECCCCHHHHHHHH
LPRTILLFTTAQIIVIILGLLLGVKAAQKVGSLFDRALSVLALVTTSIPMWWFGMIMLLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
FAFKLGWFPSNSMPNPNLTGLDHVLDVARRLVLPITTIVFVLFGGWAWVTRNIMISTLQE
HHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
DFIMVARAKGVPERKVIYGHGLRAAAPPIVTMTIFSLLGSLGGAIITESVFNWPGMGRVY
HHHHHHHCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHCCCCCCEEE
WIAIETQEINLVMGLTFISVVLYLAGVIIADISYGFLDPRVRVGASAKM
EEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]