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The map label for this gene is oppC [H]

Identifier: 18976564

GI number: 18976564

Start: 204772

End: 206196

Strand: Direct

Name: oppC [H]

Synonym: PF0192

Alternate gene names: 18976564

Gene position: 204772-206196 (Clockwise)

Preceding gene: 18976563

Following gene: 18976565

Centisome position: 10.73

GC content: 43.65

Gene sequence:

>1425_bases
ATGAGATGGGTAGACCTCAAAGAATCCCTCTCAGACTTTTGGTTTGAATTCAGAAGAGAGAAAACTGGAATTGCTGGACT
AGCTCTACTTATCTTTTGGATAGTGGTTGCTGTCTCTGCTCCATACGTCACGGAACCTAACATACCAGATAAGTGGAAGA
CCATATGGATCGAAAATCCCAAAGTTGTACCACCTACTTGGTCTTCAATATTTAGTGGTGTTAGTGAAGCCCCTCACGAA
GTAATTTATCCTGAAGAACTTCAGAAATACGTGCAATCTACGACTAGAGGGCTAATTATTGATATACCATACAACATGAA
GTATGATGTGCCACCCCAGGATATAGTGCTAATGAATATTTCGGGAAAGGCCGATGGAAGATTGAGACCTTCCTTAACAT
TAAAAATAGTTAGACCAGATGGCAAAGAGATAACTTTGCTGTCTGGAGTAAAGATAAAAGGGACAACAACTATTCAGGTT
GCGAGAGATAGCGGCGTGAGAAAGACTGTTATCAACTGGGTCAAAGGTGAAACTGGCATACAGCTTGATCCCTCAAAAGA
ACTTCAATTGGTGACTTCAATAGACACAATGAGAGTGCTTTTTGCTCAAATTTCACCTGACATGTTAGAATATCCAAAGG
CCCTCCAGGGAGAATACCACATAGTCTTCGAAATTAAGACTCCCGGGAATACCTCTGTGGATCTCTCAAATGCAAAATTA
ATTCTACCGGGAAGAACATACGGATATCTTGGAACAGATGATAAAGGTAGAGACCTTTTCGCAGGAATAGTATGGGGTTC
TAGAGTGTCTCTAACCATTGGTGTTGCAACAGCAGTGCTTACAGTTCTGGTTGGTATATTCTACGGTGTAGCTGCAGCAT
ACTTTGGAGGATGGACCGATGAAATCATGATGAGATTCCAGGAGTTCATGGCGTCAATACCAACACTACCAATCCTAATC
CTCCTGGGTACTTACTTTGGAGGACACATTCAGCTCTGGCAAATTGTATTACTGCTGACGGTTTTTGGATGGGTTGGAGT
TGCGAGAGTTGCGAGAAGTATGGCCTACCAGATTAAGGAGCAAACCTATGTTGAGGCTGCAATAGCTTTAGGTGCTGGAA
GTGGAAGAATAATCTTCAAGCACATGATGCCACAGCTCTTGCCATACGCATTTGCTCAGATGGCACTTAGCGTTCCAGGT
GCAGTTCTAGCTGAAGCTTCACTTAGCTTCCTAGGTCTTGGTGATCCAACCCAGGTGACATGGGGACAGATACTTCACGA
TGCCCAGAACGCGAATGCAGCGGTCAACGGTTACTGGTGGTGGGTCATTCCACCAGGACTTGCAATAGCACTAGTTGCAT
TCACATTCGTACTGTTAGGTACTGCATTGGATAGGATATTGAACCCAAGACTCAGGAGATTGTGA

Upstream 100 bases:

>100_bases
GTATTGTACCTTGCTGGAGTAATAATAGCTGACATCTCATATGGATTCCTAGATCCAAGAGTAAGAGTAGGTGCTTCAGC
AAAGATGTGAGGTGGTTGCA

Downstream 100 bases:

>100_bases
GGTGGTTTACATGGCTAAGAAGATACTTGAGGTTAAGAATCTTAAGATGTATTACTTCACTTCGAGAGGTCCAGTTAAGG
CAGTTGACGATGTCACCTTT

Product: oligopeptide transporter permease appc

Products: ADP; phosphate; oligopeptides [Cytoplasm] [C]

Alternate protein names: Stage 0 sporulation protein KC [H]

Number of amino acids: Translated: 474; Mature: 474

Protein sequence:

>474_residues
MRWVDLKESLSDFWFEFRREKTGIAGLALLIFWIVVAVSAPYVTEPNIPDKWKTIWIENPKVVPPTWSSIFSGVSEAPHE
VIYPEELQKYVQSTTRGLIIDIPYNMKYDVPPQDIVLMNISGKADGRLRPSLTLKIVRPDGKEITLLSGVKIKGTTTIQV
ARDSGVRKTVINWVKGETGIQLDPSKELQLVTSIDTMRVLFAQISPDMLEYPKALQGEYHIVFEIKTPGNTSVDLSNAKL
ILPGRTYGYLGTDDKGRDLFAGIVWGSRVSLTIGVATAVLTVLVGIFYGVAAAYFGGWTDEIMMRFQEFMASIPTLPILI
LLGTYFGGHIQLWQIVLLLTVFGWVGVARVARSMAYQIKEQTYVEAAIALGAGSGRIIFKHMMPQLLPYAFAQMALSVPG
AVLAEASLSFLGLGDPTQVTWGQILHDAQNANAAVNGYWWWVIPPGLAIALVAFTFVLLGTALDRILNPRLRRL

Sequences:

>Translated_474_residues
MRWVDLKESLSDFWFEFRREKTGIAGLALLIFWIVVAVSAPYVTEPNIPDKWKTIWIENPKVVPPTWSSIFSGVSEAPHE
VIYPEELQKYVQSTTRGLIIDIPYNMKYDVPPQDIVLMNISGKADGRLRPSLTLKIVRPDGKEITLLSGVKIKGTTTIQV
ARDSGVRKTVINWVKGETGIQLDPSKELQLVTSIDTMRVLFAQISPDMLEYPKALQGEYHIVFEIKTPGNTSVDLSNAKL
ILPGRTYGYLGTDDKGRDLFAGIVWGSRVSLTIGVATAVLTVLVGIFYGVAAAYFGGWTDEIMMRFQEFMASIPTLPILI
LLGTYFGGHIQLWQIVLLLTVFGWVGVARVARSMAYQIKEQTYVEAAIALGAGSGRIIFKHMMPQLLPYAFAQMALSVPG
AVLAEASLSFLGLGDPTQVTWGQILHDAQNANAAVNGYWWWVIPPGLAIALVAFTFVLLGTALDRILNPRLRRL
>Mature_474_residues
MRWVDLKESLSDFWFEFRREKTGIAGLALLIFWIVVAVSAPYVTEPNIPDKWKTIWIENPKVVPPTWSSIFSGVSEAPHE
VIYPEELQKYVQSTTRGLIIDIPYNMKYDVPPQDIVLMNISGKADGRLRPSLTLKIVRPDGKEITLLSGVKIKGTTTIQV
ARDSGVRKTVINWVKGETGIQLDPSKELQLVTSIDTMRVLFAQISPDMLEYPKALQGEYHIVFEIKTPGNTSVDLSNAKL
ILPGRTYGYLGTDDKGRDLFAGIVWGSRVSLTIGVATAVLTVLVGIFYGVAAAYFGGWTDEIMMRFQEFMASIPTLPILI
LLGTYFGGHIQLWQIVLLLTVFGWVGVARVARSMAYQIKEQTYVEAAIALGAGSGRIIFKHMMPQLLPYAFAQMALSVPG
AVLAEASLSFLGLGDPTQVTWGQILHDAQNANAAVNGYWWWVIPPGLAIALVAFTFVLLGTALDRILNPRLRRL

Specific function: Part of the binding-protein-dependent transport system for oligopeptides; probably responsible for the translocation of the substrate across the membrane. Also required for sporulation and competence [H]

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787498, Length=226, Percent_Identity=36.7256637168142, Blast_Score=115, Evalue=6e-27,
Organism=Escherichia coli, GI1787760, Length=247, Percent_Identity=31.1740890688259, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1787054, Length=225, Percent_Identity=28.4444444444444, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1789964, Length=254, Percent_Identity=34.6456692913386, Blast_Score=105, Evalue=7e-24,
Organism=Escherichia coli, GI1788505, Length=244, Percent_Identity=27.4590163934426, Blast_Score=99, Evalue=6e-22,
Organism=Escherichia coli, GI1789889, Length=244, Percent_Identity=29.0983606557377, Blast_Score=87, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 52500; Mature: 52500

Theoretical pI: Translated: 8.94; Mature: 8.94

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRWVDLKESLSDFWFEFRREKTGIAGLALLIFWIVVAVSAPYVTEPNIPDKWKTIWIENP
CCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECC
KVVPPTWSSIFSGVSEAPHEVIYPEELQKYVQSTTRGLIIDIPYNMKYDVPPQDIVLMNI
EECCCCHHHHHCCHHHCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCEEEEEE
SGKADGRLRPSLTLKIVRPDGKEITLLSGVKIKGTTTIQVARDSGVRKTVINWVKGETGI
CCCCCCCCCCCEEEEEECCCCCEEEEEECEEECCCEEEEEECCCCCHHHHHHHHCCCCCC
QLDPSKELQLVTSIDTMRVLFAQISPDMLEYPKALQGEYHIVFEIKTPGNTSVDLSNAKL
EECCCCCEEEEHHHHHHHHHHHHCCCHHHHCCHHHCCCEEEEEEEECCCCCEEEECCCEE
ILPGRTYGYLGTDDKGRDLFAGIVWGSRVSLTIGVATAVLTVLVGIFYGVAAAYFGGWTD
EECCCCCCCCCCCCCCCEEEEEEEECCEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCHH
EIMMRFQEFMASIPTLPILILLGTYFGGHIQLWQIVLLLTVFGWVGVARVARSMAYQIKE
HHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QTYVEAAIALGAGSGRIIFKHMMPQLLPYAFAQMALSVPGAVLAEASLSFLGLGDPTQVT
HHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCHHEEECCCCCCHH
WGQILHDAQNANAAVNGYWWWVIPPGLAIALVAFTFVLLGTALDRILNPRLRRL
HHHHHHHHCCCCEEEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCHHHHCC
>Mature Secondary Structure
MRWVDLKESLSDFWFEFRREKTGIAGLALLIFWIVVAVSAPYVTEPNIPDKWKTIWIENP
CCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECC
KVVPPTWSSIFSGVSEAPHEVIYPEELQKYVQSTTRGLIIDIPYNMKYDVPPQDIVLMNI
EECCCCHHHHHCCHHHCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCEEEEEE
SGKADGRLRPSLTLKIVRPDGKEITLLSGVKIKGTTTIQVARDSGVRKTVINWVKGETGI
CCCCCCCCCCCEEEEEECCCCCEEEEEECEEECCCEEEEEECCCCCHHHHHHHHCCCCCC
QLDPSKELQLVTSIDTMRVLFAQISPDMLEYPKALQGEYHIVFEIKTPGNTSVDLSNAKL
EECCCCCEEEEHHHHHHHHHHHHCCCHHHHCCHHHCCCEEEEEEEECCCCCEEEECCCEE
ILPGRTYGYLGTDDKGRDLFAGIVWGSRVSLTIGVATAVLTVLVGIFYGVAAAYFGGWTD
EECCCCCCCCCCCCCCCEEEEEEEECCEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCHH
EIMMRFQEFMASIPTLPILILLGTYFGGHIQLWQIVLLLTVFGWVGVARVARSMAYQIKE
HHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QTYVEAAIALGAGSGRIIFKHMMPQLLPYAFAQMALSVPGAVLAEASLSFLGLGDPTQVT
HHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCHHEEECCCCCCHH
WGQILHDAQNANAAVNGYWWWVIPPGLAIALVAFTFVLLGTALDRILNPRLRRL
HHHHHHHHCCCCEEEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; oligopeptides [Periplasm]; H2O [C]

Specific reaction: ATP + oligopeptides [Periplasm] + H2O = ADP + phosphate + oligopeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1901616; 1899858; 9384377 [H]