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The map label for this gene is dbh [H]

Identifier: 18311461

GI number: 18311461

Start: 2836813

End: 2837088

Strand: Reverse

Name: dbh [H]

Synonym: CPE2479

Alternate gene names: 18311461

Gene position: 2837088-2836813 (Counterclockwise)

Preceding gene: 18311462

Following gene: 18311460

Centisome position: 93.59

GC content: 33.33

Gene sequence:

>276_bases
GTGAATAAAGCAGAATTAATAACAAGCATGGCTGAAAAAAGCAACTTAACTAAAAAAGATGCTGAATTAGCTTTAAAAGC
ATTCATAGAAAGCGTTAGCGAAACTTTAGAAAATGGTGACAAAGTTCAATTAGTTGGATTCGGAACTTTCGAAACTAGAG
TAAGAGCTGAAAGAGAAGGAAGAAACCCAAGAACTAAAGAAGTTATAAAAATACCTGCTTCAATAGCTCCTGTATTCAAG
CCAGGTAAAGAGTTAAAAGAAAGAGTTAACGCTTAA

Upstream 100 bases:

>100_bases
AAATATATAATATGATAATATAAGTTGATACTAGTTCACTTGGATAACTGGTAAACAATTATTGCAGTAAACTAACTGGA
ATTTTAAGGAGGATGTAAAA

Downstream 100 bases:

>100_bases
TTTTAGATATTTTAAGTTTGGTTAATTTAACTTTAAAAAAGCCCGAGTTATTTCTCGGGCTTTTTTATCTATTAATGAAG
TTTCTTTAAGATTAAGGAGG

Product: DNA-binding protein HU

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 91; Mature: 91

Protein sequence:

>91_residues
MNKAELITSMAEKSNLTKKDAELALKAFIESVSETLENGDKVQLVGFGTFETRVRAEREGRNPRTKEVIKIPASIAPVFK
PGKELKERVNA

Sequences:

>Translated_91_residues
MNKAELITSMAEKSNLTKKDAELALKAFIESVSETLENGDKVQLVGFGTFETRVRAEREGRNPRTKEVIKIPASIAPVFK
PGKELKERVNA
>Mature_91_residues
MNKAELITSMAEKSNLTKKDAELALKAFIESVSETLENGDKVQLVGFGTFETRVRAEREGRNPRTKEVIKIPASIAPVFK
PGKELKERVNA

Specific function: Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions [H]

COG id: COG0776

COG function: function code L; Bacterial nucleoid DNA-binding protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial histone-like protein family [H]

Homologues:

Organism=Escherichia coli, GI1790433, Length=89, Percent_Identity=51.685393258427, Blast_Score=92, Evalue=6e-21,
Organism=Escherichia coli, GI1786644, Length=90, Percent_Identity=50, Blast_Score=89, Evalue=5e-20,
Organism=Escherichia coli, GI1787141, Length=91, Percent_Identity=40.6593406593407, Blast_Score=80, Evalue=4e-17,
Organism=Escherichia coli, GI1788005, Length=89, Percent_Identity=42.6966292134831, Blast_Score=77, Evalue=3e-16,

Paralogues:

None

Copy number: 1380 Molecules/Cell In: Growth-Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000119
- InterPro:   IPR020816
- InterPro:   IPR010992 [H]

Pfam domain/function: PF00216 Bac_DNA_binding [H]

EC number: NA

Molecular weight: Translated: 10102; Mature: 10102

Theoretical pI: Translated: 10.15; Mature: 10.15

Prosite motif: PS00045 HISTONE_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKAELITSMAEKSNLTKKDAELALKAFIESVSETLENGDKVQLVGFGTFETRVRAEREG
CCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHCC
RNPRTKEVIKIPASIAPVFKPGKELKERVNA
CCCCCHHHHCCCCHHCCCCCCCHHHHHHHCC
>Mature Secondary Structure
MNKAELITSMAEKSNLTKKDAELALKAFIESVSETLENGDKVQLVGFGTFETRVRAEREG
CCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHCC
RNPRTKEVIKIPASIAPVFKPGKELKERVNA
CCCCCHHHHCCCCHHCCCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 6540370 [H]