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The map label for this gene is cysS [H]

Identifier: 18311409

GI number: 18311409

Start: 2774285

End: 2775685

Strand: Reverse

Name: cysS [H]

Synonym: CPE2427

Alternate gene names: 18311409

Gene position: 2775685-2774285 (Counterclockwise)

Preceding gene: 18311410

Following gene: 18311408

Centisome position: 91.56

GC content: 30.41

Gene sequence:

>1401_bases
GTGATTAAGGTTTATAATACTTTAAACAAGAAAAAAGAAGAATTCATTCCTTTAACTCCAGGAGAAGTTAAAATGTATGT
TTGTGGTCCTACTGTGTACAACTTTTTTCACATAGGAAATGGTAGAACATTTATAGTTTTTGATACTATAAGAAGATATT
TTGAATACAGAGGATTCAAAGTTGATTTTGTTCAAAACTTTACAGATATAGATGACAAGATGATAAAAAAGGCTAATGAA
GAAGGCACTACTGTAAAGAAGATTGGAGATACTTATATAAAAGAGTATTACCAAGATGCAGATGCATTAAATATAGAAAG
AGCTACAGTTAATCCAAGAGCTACAGAATTTATTGGAGAGATAATAAAATTTGTTAAGGGATTAGTTGATAAAGGATATG
CTTATGAAGTTGATGGAGATGTTTATTTCTCAACTAAGAAGTTTGAGGGATATGGAAAGTTATCAGGACAGAACATAGAA
GATCTTCAATCAGGTGCTAGAATAAGTGTTGATGAAAGAAAAAAAGATCCAATGGACTTTGCTATATGGAAAGCTCAAAA
ACCAGGTGAACCAGCTTGGAATAGTCCTTGGGGAATGGGAAGACCAGGATGGCATATAGAATGCTCATGCATGGCTAAAA
AATTATTAGGTGAAACTATAGATATTCACGCTGGTGGATCAGACTTAAAATTCCCTCACCATGAAAATGAAATAGCACAA
AGTGAAGCTTTAACAGGTGAACCTTTTGCAAGATATTGGTTACATTCAGCCTTTGTTAATGTAAACAATGAAAAAATGTC
AAAATCATTAAATAATTTCTTTACTGCAAGAGAAATATTAGAAAGATATGATGCTGATGTTATAAGATTTTTAATGTTAT
CAGCTCACTATAGACAACAACTTAACTTTAGTGAAGATTTATTAGAATCAGCTAAGGCTTCAGTTGAAAGAATATACAAT
GCTATAGGAAATTTAGAAAACTTAATAGATGAAGTTTCTAGAGAAGAAATGAATGAGGAAGAAAAAGCTTACTTAGAGTC
ATTAAACAAATATAAAGAAAAATATATTGAAAAAATGGATGACGATTTTAATACAGCAGATGCTATAACGGCTATATTTG
ATTTAATAAAAGATACTAATACAAATATAACAATTGACTCATCAAAGGAATTAGCTCAAAAAGCTTTAGAGTTAATAAGA
GAATTAGGAGCTCCATTAGGAATGTTCCAAAAATCAACTAAAGGAAATCTAGAAGAAGAGATTGAAGCTTTAATAGCTAA
GAGACAACAAGCTAGAAAAGATAGAGATTTTGCTTTAGCTGATAAAATAAGAGATGAATTAAAAGATAGAGGAATTGTCT
TAGAAGATACACCTCAAGGTGTTAGATGGAAGATGATATAA

Upstream 100 bases:

>100_bases
TAAGATTAACGGAATTGTATATAATTAGAATATAATAATAGAGCTCACCTTATTTAATGTAGGGTGAGTTACTAATAATA
TAAGGTAGGAGGGTCAAGTA

Downstream 100 bases:

>100_bases
TTTAGATAATAAACTTGCAAAGGAACTTTCTTTTGCAAGTTATTATTTTAAAGAATTTTATTTTGATAACTATTAAAATA
AAAGTAAATTCAATAATTTA

Product: cysteinyl-tRNA synthetase

Products: NA

Alternate protein names: Cysteine--tRNA ligase; CysRS [H]

Number of amino acids: Translated: 466; Mature: 466

Protein sequence:

>466_residues
MIKVYNTLNKKKEEFIPLTPGEVKMYVCGPTVYNFFHIGNGRTFIVFDTIRRYFEYRGFKVDFVQNFTDIDDKMIKKANE
EGTTVKKIGDTYIKEYYQDADALNIERATVNPRATEFIGEIIKFVKGLVDKGYAYEVDGDVYFSTKKFEGYGKLSGQNIE
DLQSGARISVDERKKDPMDFAIWKAQKPGEPAWNSPWGMGRPGWHIECSCMAKKLLGETIDIHAGGSDLKFPHHENEIAQ
SEALTGEPFARYWLHSAFVNVNNEKMSKSLNNFFTAREILERYDADVIRFLMLSAHYRQQLNFSEDLLESAKASVERIYN
AIGNLENLIDEVSREEMNEEEKAYLESLNKYKEKYIEKMDDDFNTADAITAIFDLIKDTNTNITIDSSKELAQKALELIR
ELGAPLGMFQKSTKGNLEEEIEALIAKRQQARKDRDFALADKIRDELKDRGIVLEDTPQGVRWKMI

Sequences:

>Translated_466_residues
MIKVYNTLNKKKEEFIPLTPGEVKMYVCGPTVYNFFHIGNGRTFIVFDTIRRYFEYRGFKVDFVQNFTDIDDKMIKKANE
EGTTVKKIGDTYIKEYYQDADALNIERATVNPRATEFIGEIIKFVKGLVDKGYAYEVDGDVYFSTKKFEGYGKLSGQNIE
DLQSGARISVDERKKDPMDFAIWKAQKPGEPAWNSPWGMGRPGWHIECSCMAKKLLGETIDIHAGGSDLKFPHHENEIAQ
SEALTGEPFARYWLHSAFVNVNNEKMSKSLNNFFTAREILERYDADVIRFLMLSAHYRQQLNFSEDLLESAKASVERIYN
AIGNLENLIDEVSREEMNEEEKAYLESLNKYKEKYIEKMDDDFNTADAITAIFDLIKDTNTNITIDSSKELAQKALELIR
ELGAPLGMFQKSTKGNLEEEIEALIAKRQQARKDRDFALADKIRDELKDRGIVLEDTPQGVRWKMI
>Mature_466_residues
MIKVYNTLNKKKEEFIPLTPGEVKMYVCGPTVYNFFHIGNGRTFIVFDTIRRYFEYRGFKVDFVQNFTDIDDKMIKKANE
EGTTVKKIGDTYIKEYYQDADALNIERATVNPRATEFIGEIIKFVKGLVDKGYAYEVDGDVYFSTKKFEGYGKLSGQNIE
DLQSGARISVDERKKDPMDFAIWKAQKPGEPAWNSPWGMGRPGWHIECSCMAKKLLGETIDIHAGGSDLKFPHHENEIAQ
SEALTGEPFARYWLHSAFVNVNNEKMSKSLNNFFTAREILERYDADVIRFLMLSAHYRQQLNFSEDLLESAKASVERIYN
AIGNLENLIDEVSREEMNEEEKAYLESLNKYKEKYIEKMDDDFNTADAITAIFDLIKDTNTNITIDSSKELAQKALELIR
ELGAPLGMFQKSTKGNLEEEIEALIAKRQQARKDRDFALADKIRDELKDRGIVLEDTPQGVRWKMI

Specific function: Unknown

COG id: COG0215

COG function: function code J; Cysteinyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI13375695, Length=491, Percent_Identity=33.6048879837067, Blast_Score=257, Evalue=2e-68,
Organism=Homo sapiens, GI303304987, Length=231, Percent_Identity=45.8874458874459, Blast_Score=215, Evalue=6e-56,
Organism=Homo sapiens, GI10835051, Length=231, Percent_Identity=45.8874458874459, Blast_Score=215, Evalue=6e-56,
Organism=Homo sapiens, GI21269877, Length=231, Percent_Identity=45.8874458874459, Blast_Score=215, Evalue=6e-56,
Organism=Homo sapiens, GI62240992, Length=231, Percent_Identity=45.8874458874459, Blast_Score=215, Evalue=6e-56,
Organism=Escherichia coli, GI1786737, Length=475, Percent_Identity=47.1578947368421, Blast_Score=440, Evalue=1e-124,
Organism=Caenorhabditis elegans, GI17509797, Length=347, Percent_Identity=37.1757925072046, Blast_Score=202, Evalue=5e-52,
Organism=Caenorhabditis elegans, GI17509795, Length=347, Percent_Identity=37.1757925072046, Blast_Score=201, Evalue=5e-52,
Organism=Saccharomyces cerevisiae, GI6324082, Length=413, Percent_Identity=34.6246973365617, Blast_Score=215, Evalue=1e-56,
Organism=Drosophila melanogaster, GI19922218, Length=503, Percent_Identity=32.6043737574553, Blast_Score=252, Evalue=4e-67,
Organism=Drosophila melanogaster, GI19922364, Length=310, Percent_Identity=36.4516129032258, Blast_Score=201, Evalue=6e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015803
- InterPro:   IPR015273
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF09190 DALR_2; PF01406 tRNA-synt_1e [H]

EC number: =6.1.1.16 [H]

Molecular weight: Translated: 53650; Mature: 53650

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKVYNTLNKKKEEFIPLTPGEVKMYVCGPTVYNFFHIGNGRTFIVFDTIRRYFEYRGFK
CEEECCHHCHHHHHCCCCCCCCEEEEEECCHHEEEEEECCCCEEEEHHHHHHHHHHCCCE
VDFVQNFTDIDDKMIKKANEEGTTVKKIGDTYIKEYYQDADALNIERATVNPRATEFIGE
EEHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHH
IIKFVKGLVDKGYAYEVDGDVYFSTKKFEGYGKLSGQNIEDLQSGARISVDERKKDPMDF
HHHHHHHHHCCCCEEEECCCEEEEECCCCCCCCCCCCCHHHHHCCCEEEEHHCCCCCCCE
AIWKAQKPGEPAWNSPWGMGRPGWHIECSCMAKKLLGETIDIHAGGSDLKFPHHENEIAQ
EEEECCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHCCCCEEEECCCCCCCCCCCHHHHHH
SEALTGEPFARYWLHSAFVNVNNEKMSKSLNNFFTAREILERYDADVIRFLMLSAHYRQQ
HHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LNFSEDLLESAKASVERIYNAIGNLENLIDEVSREEMNEEEKAYLESLNKYKEKYIEKMD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHC
DDFNTADAITAIFDLIKDTNTNITIDSSKELAQKALELIRELGAPLGMFQKSTKGNLEEE
CCCCHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHHCCCHHHHHCCCCCCHHHH
IEALIAKRQQARKDRDFALADKIRDELKDRGIVLEDTPQGVRWKMI
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCEEEECCCCCCEEECC
>Mature Secondary Structure
MIKVYNTLNKKKEEFIPLTPGEVKMYVCGPTVYNFFHIGNGRTFIVFDTIRRYFEYRGFK
CEEECCHHCHHHHHCCCCCCCCEEEEEECCHHEEEEEECCCCEEEEHHHHHHHHHHCCCE
VDFVQNFTDIDDKMIKKANEEGTTVKKIGDTYIKEYYQDADALNIERATVNPRATEFIGE
EEHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHH
IIKFVKGLVDKGYAYEVDGDVYFSTKKFEGYGKLSGQNIEDLQSGARISVDERKKDPMDF
HHHHHHHHHCCCCEEEECCCEEEEECCCCCCCCCCCCCHHHHHCCCEEEEHHCCCCCCCE
AIWKAQKPGEPAWNSPWGMGRPGWHIECSCMAKKLLGETIDIHAGGSDLKFPHHENEIAQ
EEEECCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHCCCCEEEECCCCCCCCCCCHHHHHH
SEALTGEPFARYWLHSAFVNVNNEKMSKSLNNFFTAREILERYDADVIRFLMLSAHYRQQ
HHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LNFSEDLLESAKASVERIYNAIGNLENLIDEVSREEMNEEEKAYLESLNKYKEKYIEKMD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHC
DDFNTADAITAIFDLIKDTNTNITIDSSKELAQKALELIRELGAPLGMFQKSTKGNLEEE
CCCCHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHHCCCHHHHHCCCCCCHHHH
IEALIAKRQQARKDRDFALADKIRDELKDRGIVLEDTPQGVRWKMI
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCEEEECCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA