Click here to switch to the map view.

The map label for this gene is spoVE [H]

Identifier: 18311118

GI number: 18311118

Start: 2446824

End: 2447948

Strand: Reverse

Name: spoVE [H]

Synonym: CPE2136

Alternate gene names: 18311118

Gene position: 2447948-2446824 (Counterclockwise)

Preceding gene: 18311119

Following gene: 18311117

Centisome position: 80.75

GC content: 31.73

Gene sequence:

>1125_bases
ATGCTTAGTAGACTAAAACTAGATAGTAAACTAAGAAGAGAAATTGATTATAAGCTTTTAGTATCTATGATATTAATAGT
ACTGTTTGGAATATTAAACATATACTTAGGGACAAAGTCTCAAAGAGGATTTTTTTTCGCTAAGAAACAGTTAATATGGT
TTATAATATCAATGGCTGCATTGTACATAATATTACTTTGGAATTATAACATAATTTATAATTATGTTGAGATATTCTAT
TGGGGATCCATAGTTCTACTTATAATAACCAGATTTGCAGGAAGTGTAATAAATGGTGCTAGAGGATGGATTGTATTAGG
TCCTGTAAGTATTCAGCCCTCGGAACTGGCCAAAACGGCCATGATACTTATGCTGGCCAAGAAGATGGAACAAGTTGATT
TAAGAATAAATGACTTTAGAAATTTTATTAAGGTTGCCATGTATGCAATAATACCAATGATATTTATAGTTGTACAACCT
GACATGGGTATGACTATGGTTTCATTTTTTATAGCACTTGGTATATTCTTTGCAGCTGGATTAGATATGAAAGTAATAGG
TGCAGGGCTTTTATCAATAATAGTGGCAATAGCCTTAGTTTGGAATTCAGGGCTTATAAAAGACTATCAAAAGGATAGAC
TTGTTGGATTCTTAAATCCTGATGGAGATGAGTTAGGTATAAACCTTCAATTAACTCAATCAAAAATAGGGATTGGATCT
GGAGGATTCTTTGGAACTGGGTTAGATTTAAATGGAGAAGTTGGTGGTTATTCCTCAGAATTCGTACCAGAAAGGCAAAC
AGACTTTATATTCGCTGTAATAGGTGAACATTGGGGAACAGTAGGAGGAATAGTATTACTATTATTATACGCAATAATGA
TATATAGAATAATAATGACGGCTAAAACCTCTAAGGATATATTTGGCTCCATAATATGTGTTGGATTTGCCTCTTATTTT
ATATTTGCTATATTACAGAATATAGGAATGACAATAGGTATAATGCCTATAACAGGAATAACATTACCATTAGTAAGCTA
TGGAGGAAGTTCATTGCTTACAACTATAGTGAGTATAGCCTTGGTTTTAAATATATCTATGAGAAAGAAAAAGTTAAAAT
TCTAA

Upstream 100 bases:

>100_bases
GTCTTTTAAAAAGTTCAGAATTTTGTAATTGAAAATAGGTAAAAATAAAGTATTATATAAATAGTTATGTTAAATAAATA
AAATTTATGGAGGTACTATA

Downstream 100 bases:

>100_bases
TAAAAATAAAAGTATTAAGATCAATAATGATTTTAATACTTTTATTTTTTTATATCTATTATATTTCACTTTGTAATAAA
AGTTCTATAAGATGCATAAA

Product: cell cycle protein, FtsW/RodA/SpoVE family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 374; Mature: 374

Protein sequence:

>374_residues
MLSRLKLDSKLRREIDYKLLVSMILIVLFGILNIYLGTKSQRGFFFAKKQLIWFIISMAALYIILLWNYNIIYNYVEIFY
WGSIVLLIITRFAGSVINGARGWIVLGPVSIQPSELAKTAMILMLAKKMEQVDLRINDFRNFIKVAMYAIIPMIFIVVQP
DMGMTMVSFFIALGIFFAAGLDMKVIGAGLLSIIVAIALVWNSGLIKDYQKDRLVGFLNPDGDELGINLQLTQSKIGIGS
GGFFGTGLDLNGEVGGYSSEFVPERQTDFIFAVIGEHWGTVGGIVLLLLYAIMIYRIIMTAKTSKDIFGSIICVGFASYF
IFAILQNIGMTIGIMPITGITLPLVSYGGSSLLTTIVSIALVLNISMRKKKLKF

Sequences:

>Translated_374_residues
MLSRLKLDSKLRREIDYKLLVSMILIVLFGILNIYLGTKSQRGFFFAKKQLIWFIISMAALYIILLWNYNIIYNYVEIFY
WGSIVLLIITRFAGSVINGARGWIVLGPVSIQPSELAKTAMILMLAKKMEQVDLRINDFRNFIKVAMYAIIPMIFIVVQP
DMGMTMVSFFIALGIFFAAGLDMKVIGAGLLSIIVAIALVWNSGLIKDYQKDRLVGFLNPDGDELGINLQLTQSKIGIGS
GGFFGTGLDLNGEVGGYSSEFVPERQTDFIFAVIGEHWGTVGGIVLLLLYAIMIYRIIMTAKTSKDIFGSIICVGFASYF
IFAILQNIGMTIGIMPITGITLPLVSYGGSSLLTTIVSIALVLNISMRKKKLKF
>Mature_374_residues
MLSRLKLDSKLRREIDYKLLVSMILIVLFGILNIYLGTKSQRGFFFAKKQLIWFIISMAALYIILLWNYNIIYNYVEIFY
WGSIVLLIITRFAGSVINGARGWIVLGPVSIQPSELAKTAMILMLAKKMEQVDLRINDFRNFIKVAMYAIIPMIFIVVQP
DMGMTMVSFFIALGIFFAAGLDMKVIGAGLLSIIVAIALVWNSGLIKDYQKDRLVGFLNPDGDELGINLQLTQSKIGIGS
GGFFGTGLDLNGEVGGYSSEFVPERQTDFIFAVIGEHWGTVGGIVLLLLYAIMIYRIIMTAKTSKDIFGSIICVGFASYF
IFAILQNIGMTIGIMPITGITLPLVSYGGSSLLTTIVSIALVLNISMRKKKLKF

Specific function: This is one of the proteins responsible for the rod shape of the cell. It is required for the expression of the enzymatic activity of PBP2, which is thought to synthesize peptidoglycan in the step of initiation of cell elongation [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=335, Percent_Identity=32.8358208955224, Blast_Score=162, Evalue=4e-41,
Organism=Escherichia coli, GI1786853, Length=291, Percent_Identity=36.426116838488, Blast_Score=161, Evalue=7e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR011923 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 41510; Mature: 41510

Theoretical pI: Translated: 9.93; Mature: 9.93

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSRLKLDSKLRREIDYKLLVSMILIVLFGILNIYLGTKSQRGFFFAKKQLIWFIISMAA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
LYIILLWNYNIIYNYVEIFYWGSIVLLIITRFAGSVINGARGWIVLGPVSIQPSELAKTA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHH
MILMLAKKMEQVDLRINDFRNFIKVAMYAIIPMIFIVVQPDMGMTMVSFFIALGIFFAAG
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCC
LDMKVIGAGLLSIIVAIALVWNSGLIKDYQKDRLVGFLNPDGDELGINLQLTQSKIGIGS
CCHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCEEEEECCCCCCEEEEEEEECCCCCCCC
GGFFGTGLDLNGEVGGYSSEFVPERQTDFIFAVIGEHWGTVGGIVLLLLYAIMIYRIIMT
CCCEECCCCCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
AKTSKDIFGSIICVGFASYFIFAILQNIGMTIGIMPITGITLPLVSYGGSSLLTTIVSIA
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHCCCHHHHHHHHHHH
LVLNISMRKKKLKF
HHHHHHHHHHHCCC
>Mature Secondary Structure
MLSRLKLDSKLRREIDYKLLVSMILIVLFGILNIYLGTKSQRGFFFAKKQLIWFIISMAA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
LYIILLWNYNIIYNYVEIFYWGSIVLLIITRFAGSVINGARGWIVLGPVSIQPSELAKTA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHH
MILMLAKKMEQVDLRINDFRNFIKVAMYAIIPMIFIVVQPDMGMTMVSFFIALGIFFAAG
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCC
LDMKVIGAGLLSIIVAIALVWNSGLIKDYQKDRLVGFLNPDGDELGINLQLTQSKIGIGS
CCHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCEEEEECCCCCCEEEEEEEECCCCCCCC
GGFFGTGLDLNGEVGGYSSEFVPERQTDFIFAVIGEHWGTVGGIVLLLLYAIMIYRIIMT
CCCEECCCCCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
AKTSKDIFGSIICVGFASYFIFAILQNIGMTIGIMPITGITLPLVSYGGSSLLTTIVSIA
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHCCCHHHHHHHHHHH
LVLNISMRKKKLKF
HHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]