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The map label for this gene is fmhB [H]

Identifier: 18311072

GI number: 18311072

Start: 2398089

End: 2399426

Strand: Direct

Name: fmhB [H]

Synonym: CPE2090

Alternate gene names: 18311072

Gene position: 2398089-2399426 (Clockwise)

Preceding gene: 18311071

Following gene: 18311073

Centisome position: 79.11

GC content: 28.03

Gene sequence:

>1338_bases
TTGTATAAATTTGTAGAAATAAATTCATCAGAAATTGATAAATTTAATGAATCTGATAGAAAGGGTCACATATTCCAAAC
ATCTTATTGGGCTGAATTAAAAAAAGATTGGAAGAAGAAATTTATAGCAGGATATGATAATGATAATAATATGGTTATCA
CAGCTACTATACTTTTAAGAAAAGCACCATACATAAATAAATATATGGGATATATTCCAAGAAGTTTTACATGTGACTAC
AACAATAAAAAATTACTAATAGAATTTACTGAATATCTAAGAGAATTTGCTAAAAAGAATAATATAAGCTTTATAACAAT
AGATCCAGATATCCATTTAAAAGAAAATGAAGAAGCTCTTTCAGAAGGTACTGAAATAAAGAACTTCCTTAAGAGTTTAG
GTTACAAAAACACAGATAGTAAAAACTTTGAAGCTATACAACCAAACTTTGTATTTAGACTTCCACTTCCAACTGAAGGG
AATAAAATGGATATTAAGAAGGCTGTATTTAAAAAATTCTCTAGTAAAACTAGATATAACATAAAAGTTGCTGAGGAAAG
AGGATTATCAGTTGAGGTTTATGATAAAGAAACTTTAAATGAAGATGTATTAGACAGATTCCATGAAATCATGGTTACAA
CTGGTAAGAGAGATAACTTCTTAGTAAGACATAGAGAATATTTTAAGGACATGATAGATTACTTATATCCACATTGTAGA
TTATACATGGTTAAGTATAGCTACGAAAATGACTTCAACAGATTATCAGAAAAATTAAACAAGCAAGAAGAGGCTAAAAC
TAAGGCTATTAACAAAATAGAAGAACTTAAAGTAAAGCTTGATGTTGAAACTGATGAGGATAAGAAATCAAGAATTGAAA
AGAAATTAAATGACCAAGATAAGAGACTTAAAGAAGCTGAAAGACAAATAGAAGGCTTTAAAAAGAAAATATCTGATATA
GAACCTTTCAAAGGTCAAGAAATATATCTTTCAGGATCAATATACTTATACTACGGAAACAAAGCATGGTATCTTTACGG
AGCTTCAGAAAATATATTAAGAGATACAATGCCTAACTTTGCTATGCAATGGTCAATGATTTGTGACTCTATTGATCTAG
GTTGTGATGTATATGACTTTAGAGGTGTTTCTGGAGACTTAAATCCTGAAAATCCACTATATGGACTTTATAAATTCAAA
AAAGGATTTAACGGAAACTTCGTAGAATTTATAGGAGAGTTTGATATTGTTGTTGATAATGGAATATACACACTTTATAA
AAAAGCTTTCCCACAATTCAAAAAAATAAGAAATGCTATAATGAATAAGAAACAATAA

Upstream 100 bases:

>100_bases
GTTACACTTGAACAGAAAATTATTTCATATTACAATATACTTATTATGTCTTAATGTATATATATGTTTAGAACTGATGA
AGTTTAAGGAGGAAACTAAA

Downstream 100 bases:

>100_bases
AAAAAGAATGCATATGCATTCTTTTTTTATTTAAAAACTTTATATAAAAAATTTCTCTAAAAAAGCTTCTATACATACTT
AAAATTAAATAATTTTTATT

Product: FemAB family protein

Products: NA

Alternate protein names: Factor essential for expression of methicillin resistance X [H]

Number of amino acids: Translated: 445; Mature: 445

Protein sequence:

>445_residues
MYKFVEINSSEIDKFNESDRKGHIFQTSYWAELKKDWKKKFIAGYDNDNNMVITATILLRKAPYINKYMGYIPRSFTCDY
NNKKLLIEFTEYLREFAKKNNISFITIDPDIHLKENEEALSEGTEIKNFLKSLGYKNTDSKNFEAIQPNFVFRLPLPTEG
NKMDIKKAVFKKFSSKTRYNIKVAEERGLSVEVYDKETLNEDVLDRFHEIMVTTGKRDNFLVRHREYFKDMIDYLYPHCR
LYMVKYSYENDFNRLSEKLNKQEEAKTKAINKIEELKVKLDVETDEDKKSRIEKKLNDQDKRLKEAERQIEGFKKKISDI
EPFKGQEIYLSGSIYLYYGNKAWYLYGASENILRDTMPNFAMQWSMICDSIDLGCDVYDFRGVSGDLNPENPLYGLYKFK
KGFNGNFVEFIGEFDIVVDNGIYTLYKKAFPQFKKIRNAIMNKKQ

Sequences:

>Translated_445_residues
MYKFVEINSSEIDKFNESDRKGHIFQTSYWAELKKDWKKKFIAGYDNDNNMVITATILLRKAPYINKYMGYIPRSFTCDY
NNKKLLIEFTEYLREFAKKNNISFITIDPDIHLKENEEALSEGTEIKNFLKSLGYKNTDSKNFEAIQPNFVFRLPLPTEG
NKMDIKKAVFKKFSSKTRYNIKVAEERGLSVEVYDKETLNEDVLDRFHEIMVTTGKRDNFLVRHREYFKDMIDYLYPHCR
LYMVKYSYENDFNRLSEKLNKQEEAKTKAINKIEELKVKLDVETDEDKKSRIEKKLNDQDKRLKEAERQIEGFKKKISDI
EPFKGQEIYLSGSIYLYYGNKAWYLYGASENILRDTMPNFAMQWSMICDSIDLGCDVYDFRGVSGDLNPENPLYGLYKFK
KGFNGNFVEFIGEFDIVVDNGIYTLYKKAFPQFKKIRNAIMNKKQ
>Mature_445_residues
MYKFVEINSSEIDKFNESDRKGHIFQTSYWAELKKDWKKKFIAGYDNDNNMVITATILLRKAPYINKYMGYIPRSFTCDY
NNKKLLIEFTEYLREFAKKNNISFITIDPDIHLKENEEALSEGTEIKNFLKSLGYKNTDSKNFEAIQPNFVFRLPLPTEG
NKMDIKKAVFKKFSSKTRYNIKVAEERGLSVEVYDKETLNEDVLDRFHEIMVTTGKRDNFLVRHREYFKDMIDYLYPHCR
LYMVKYSYENDFNRLSEKLNKQEEAKTKAINKIEELKVKLDVETDEDKKSRIEKKLNDQDKRLKEAERQIEGFKKKISDI
EPFKGQEIYLSGSIYLYYGNKAWYLYGASENILRDTMPNFAMQWSMICDSIDLGCDVYDFRGVSGDLNPENPLYGLYKFK
KGFNGNFVEFIGEFDIVVDNGIYTLYKKAFPQFKKIRNAIMNKKQ

Specific function: Catalyzes the incorporation of the first glycine of the pentaglycine interpeptide bridge, which is characteristic of the S.aureus peptidoglycan. This glycine is added to the epsilon-amino group of the L-lysine of the membrane-bound lipid II intermediate (

COG id: COG2348

COG function: function code V; Uncharacterized protein involved in methicillin resistance

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the femABX family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016181
- InterPro:   IPR003447 [H]

Pfam domain/function: PF02388 FemAB [H]

EC number: NA

Molecular weight: Translated: 52737; Mature: 52737

Theoretical pI: Translated: 8.91; Mature: 8.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYKFVEINSSEIDKFNESDRKGHIFQTSYWAELKKDWKKKFIAGYDNDNNMVITATILLR
CCEEEECCCHHHHCCCCCCCCCCEEEHHHHHHHHHHHHHHHEECCCCCCCEEEEEEEEHH
KAPYINKYMGYIPRSFTCDYNNKKLLIEFTEYLREFAKKNNISFITIDPDIHLKENEEAL
CCCHHHHHHHCCCCCEEECCCCCEEEEHHHHHHHHHHHCCCCEEEEECCCEEECCCHHHH
SEGTEIKNFLKSLGYKNTDSKNFEAIQPNFVFRLPLPTEGNKMDIKKAVFKKFSSKTRYN
HCCHHHHHHHHHCCCCCCCCCCCEEECCCEEEEECCCCCCCCHHHHHHHHHHHCCCCEEE
IKVAEERGLSVEVYDKETLNEDVLDRFHEIMVTTGKRDNFLVRHREYFKDMIDYLYPHCR
EEEECCCCCEEEEECHHHCCHHHHHHHHHHHEECCCCCCEEHHHHHHHHHHHHHHCCCEE
LYMVKYSYENDFNRLSEKLNKQEEAKTKAINKIEELKVKLDVETDEDKKSRIEKKLNDQD
EEEEEECCCCHHHHHHHHHCHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHHCHHH
KRLKEAERQIEGFKKKISDIEPFKGQEIYLSGSIYLYYGNKAWYLYGASENILRDTMPNF
HHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEEEECCEEEEEEECCCHHHHHCCCHH
AMQWSMICDSIDLGCDVYDFRGVSGDLNPENPLYGLYKFKKGFNGNFVEFIGEFDIVVDN
HHHHHHHHCCCCCCCCEEECCCCCCCCCCCCCCCHHHHHHCCCCCCHHHHHCCEEEEEEC
GIYTLYKKAFPQFKKIRNAIMNKKQ
CHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MYKFVEINSSEIDKFNESDRKGHIFQTSYWAELKKDWKKKFIAGYDNDNNMVITATILLR
CCEEEECCCHHHHCCCCCCCCCCEEEHHHHHHHHHHHHHHHEECCCCCCCEEEEEEEEHH
KAPYINKYMGYIPRSFTCDYNNKKLLIEFTEYLREFAKKNNISFITIDPDIHLKENEEAL
CCCHHHHHHHCCCCCEEECCCCCEEEEHHHHHHHHHHHCCCCEEEEECCCEEECCCHHHH
SEGTEIKNFLKSLGYKNTDSKNFEAIQPNFVFRLPLPTEGNKMDIKKAVFKKFSSKTRYN
HCCHHHHHHHHHCCCCCCCCCCCEEECCCEEEEECCCCCCCCHHHHHHHHHHHCCCCEEE
IKVAEERGLSVEVYDKETLNEDVLDRFHEIMVTTGKRDNFLVRHREYFKDMIDYLYPHCR
EEEECCCCCEEEEECHHHCCHHHHHHHHHHHEECCCCCCEEHHHHHHHHHHHHHHCCCEE
LYMVKYSYENDFNRLSEKLNKQEEAKTKAINKIEELKVKLDVETDEDKKSRIEKKLNDQD
EEEEEECCCCHHHHHHHHHCHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHHCHHH
KRLKEAERQIEGFKKKISDIEPFKGQEIYLSGSIYLYYGNKAWYLYGASENILRDTMPNF
HHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEEEECCEEEEEEECCCHHHHHCCCHH
AMQWSMICDSIDLGCDVYDFRGVSGDLNPENPLYGLYKFKKGFNGNFVEFIGEFDIVVDN
HHHHHHHHCCCCCCCCEEECCCCCCCCCCCCCCCHHHHHHCCCCCCHHHHHCCEEEEEEC
GIYTLYKKAFPQFKKIRNAIMNKKQ
CHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA