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The map label for this gene is dgkA [H]

Identifier: 18310999

GI number: 18310999

Start: 2309820

End: 2310518

Strand: Reverse

Name: dgkA [H]

Synonym: CPE2017

Alternate gene names: 18310999

Gene position: 2310518-2309820 (Counterclockwise)

Preceding gene: 18311000

Following gene: 18310998

Centisome position: 76.22

GC content: 31.04

Gene sequence:

>699_bases
ATGAAGGTAAGAAAACTTATTGATAGCTTTAATTATGCAATAGATGGTATAATATATGCCTTAAGAACTCAAAGAAACAT
GAGAATACATTTTATAGTAGCTTTAATTATATTATCAGCTTGTTTTGTTTATGATATAAGCAAAATAGAGTTTATAATAC
TAGCCATAACAATAACCATGGTAATAGCAGCAGAATTAGTTAATACTGCTATAGAAAGCGCTATAGATCTAAGTACAAAT
TACTATCATCCTTTAGCTAAAATAGCTAAAAATACAGCAGCTGGGGCAGTACTTATAACTGCAATAAATTCTGTCTTAGT
GGGGTATATTATATTTTGGGATGAGCTTACCAATATAACTTTTAGAATTATGGATAGAGTAAAAGAAACAGAGCCTTATA
TTATATTTATTGTATTAGCCATAGTATGCATAGTTGTGGTTGCTGCAAAGGCTTATTTTGGAGAAGGAACCCCATTAAAG
GGTGGAATGCCTTCAGGACACAGTGCTATAGCCTTTTCTATAGCTACGGCTATATCACTTATAAGTAATTCTCATATTAT
AATTATACTTAGTTATTTAATGGCTTTAATAACGGCCCAGAGCAGAGTGGATTCAGAAGTCCATAGCGTATGGGAAGTTA
TTGCAGGAGCAATATTAGGAACGCTTATAACAATTTTAATTTTTAAAATATTTAGTTGA

Upstream 100 bases:

>100_bases
GGAAGAAAAAGCTAGAATGAGAGGAAGAGAAGAGGAGTTACTTGGTAAGTTAAATATAACAAGGGAAAGCTAAGGTATGA
GAATGGTTTAGGAGAATATT

Downstream 100 bases:

>100_bases
TAAATTTTTAGTATTTAAATTTTAGGATGGAGGATGAGTTATTATGAAAAAAGAACTTATAAAAAAAGCTTTAGAGGCAA
GAGAATTGGCATATTGTCCA

Product: diacylglycerol kinase/PAP2 family protein

Products: NA

Alternate protein names: UdpK [H]

Number of amino acids: Translated: 232; Mature: 232

Protein sequence:

>232_residues
MKVRKLIDSFNYAIDGIIYALRTQRNMRIHFIVALIILSACFVYDISKIEFIILAITITMVIAAELVNTAIESAIDLSTN
YYHPLAKIAKNTAAGAVLITAINSVLVGYIIFWDELTNITFRIMDRVKETEPYIIFIVLAIVCIVVVAAKAYFGEGTPLK
GGMPSGHSAIAFSIATAISLISNSHIIIILSYLMALITAQSRVDSEVHSVWEVIAGAILGTLITILIFKIFS

Sequences:

>Translated_232_residues
MKVRKLIDSFNYAIDGIIYALRTQRNMRIHFIVALIILSACFVYDISKIEFIILAITITMVIAAELVNTAIESAIDLSTN
YYHPLAKIAKNTAAGAVLITAINSVLVGYIIFWDELTNITFRIMDRVKETEPYIIFIVLAIVCIVVVAAKAYFGEGTPLK
GGMPSGHSAIAFSIATAISLISNSHIIIILSYLMALITAQSRVDSEVHSVWEVIAGAILGTLITILIFKIFS
>Mature_232_residues
MKVRKLIDSFNYAIDGIIYALRTQRNMRIHFIVALIILSACFVYDISKIEFIILAITITMVIAAELVNTAIESAIDLSTN
YYHPLAKIAKNTAAGAVLITAINSVLVGYIIFWDELTNITFRIMDRVKETEPYIIFIVLAIVCIVVVAAKAYFGEGTPLK
GGMPSGHSAIAFSIATAISLISNSHIIIILSYLMALITAQSRVDSEVHSVWEVIAGAILGTLITILIFKIFS

Specific function: Catalyzes the phosphorylation of undecaprenol, which is probably the primary physiological substrate. Is also able to phosphorylate diacylglycerol, albeit with very low efficiency. May play a role in adaptability to environmental stress conditions such as

COG id: COG0818

COG function: function code M; Diacylglycerol kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial diacylglycerol kinase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000829 [H]

Pfam domain/function: PF01219 DAGK_prokar [H]

EC number: =2.7.1.66 [H]

Molecular weight: Translated: 25443; Mature: 25443

Theoretical pI: Translated: 7.62; Mature: 7.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVRKLIDSFNYAIDGIIYALRTQRNMRIHFIVALIILSACFVYDISKIEFIILAITITM
CCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VIAAELVNTAIESAIDLSTNYYHPLAKIAKNTAAGAVLITAINSVLVGYIIFWDELTNIT
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
FRIMDRVKETEPYIIFIVLAIVCIVVVAAKAYFGEGTPLKGGMPSGHSAIAFSIATAISL
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHH
ISNSHIIIILSYLMALITAQSRVDSEVHSVWEVIAGAILGTLITILIFKIFS
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKVRKLIDSFNYAIDGIIYALRTQRNMRIHFIVALIILSACFVYDISKIEFIILAITITM
CCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VIAAELVNTAIESAIDLSTNYYHPLAKIAKNTAAGAVLITAINSVLVGYIIFWDELTNIT
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
FRIMDRVKETEPYIIFIVLAIVCIVVVAAKAYFGEGTPLKGGMPSGHSAIAFSIATAISL
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHH
ISNSHIIIILSYLMALITAQSRVDSEVHSVWEVIAGAILGTLITILIFKIFS
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8407794; 9422608; 12397186 [H]