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The map label for this gene is cdd [H]

Identifier: 18310998

GI number: 18310998

Start: 2309378

End: 2309776

Strand: Reverse

Name: cdd [H]

Synonym: CPE2016

Alternate gene names: 18310998

Gene position: 2309776-2309378 (Counterclockwise)

Preceding gene: 18310999

Following gene: 18310997

Centisome position: 76.19

GC content: 31.08

Gene sequence:

>399_bases
ATGAAAAAAGAACTTATAAAAAAAGCTTTAGAGGCAAGAGAATTGGCATATTGTCCATATTCAAATTTTAAGGTAGGTGC
AGCTGCTTTATTTGAGGATGGTAAAATATATACAGGATGCAATATTGAAAATGCATCATTTGGAGCAACAAACTGTGCTG
AGAGAACTGCTATATTTAAAGGGGTTTCAGAAGGAGCAAGAGTCTTAAAGGCTATGGCTTTAGTAGGAGATTTAAATTCA
TACACATATCCATGTGGTATATGCAGACAAGTAATAGTAGAGTTTGCAGAAGATAAAGATATAAAAATATTCATAGTAAA
AAGTGAAGATGATTATATAGAGACAACATTAGATGAAATTTTACCTGGATCTTTTACTAAAAAGGATCTAGAAAAATAG

Upstream 100 bases:

>100_bases
GCAGGAGCAATATTAGGAACGCTTATAACAATTTTAATTTTTAAAATATTTAGTTGATAAATTTTTAGTATTTAAATTTT
AGGATGGAGGATGAGTTATT

Downstream 100 bases:

>100_bases
GAGGAAATATGTTTAAATCAGGATTTATAACAATTGTTGGTAGACCAAATGTAGGTAAGTCAACATTAACAAACTTATTA
ATGGGAGAAAAACTTTCAAT

Product: cytidine deaminase

Products: NA

Alternate protein names: CDA; Cytidine aminohydrolase [H]

Number of amino acids: Translated: 132; Mature: 132

Protein sequence:

>132_residues
MKKELIKKALEARELAYCPYSNFKVGAAALFEDGKIYTGCNIENASFGATNCAERTAIFKGVSEGARVLKAMALVGDLNS
YTYPCGICRQVIVEFAEDKDIKIFIVKSEDDYIETTLDEILPGSFTKKDLEK

Sequences:

>Translated_132_residues
MKKELIKKALEARELAYCPYSNFKVGAAALFEDGKIYTGCNIENASFGATNCAERTAIFKGVSEGARVLKAMALVGDLNS
YTYPCGICRQVIVEFAEDKDIKIFIVKSEDDYIETTLDEILPGSFTKKDLEK
>Mature_132_residues
MKKELIKKALEARELAYCPYSNFKVGAAALFEDGKIYTGCNIENASFGATNCAERTAIFKGVSEGARVLKAMALVGDLNS
YTYPCGICRQVIVEFAEDKDIKIFIVKSEDDYIETTLDEILPGSFTKKDLEK

Specific function: This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis [H]

COG id: COG0295

COG function: function code F; Cytidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI11386157, Length=137, Percent_Identity=45.2554744525547, Blast_Score=123, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI17551074, Length=132, Percent_Identity=47.7272727272727, Blast_Score=120, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17540514, Length=129, Percent_Identity=44.9612403100775, Blast_Score=113, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6323274, Length=130, Percent_Identity=40, Blast_Score=89, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24582741, Length=128, Percent_Identity=46.875, Blast_Score=118, Evalue=9e-28,
Organism=Drosophila melanogaster, GI19920920, Length=139, Percent_Identity=46.0431654676259, Blast_Score=113, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24582744, Length=139, Percent_Identity=45.3237410071942, Blast_Score=112, Evalue=7e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002125
- InterPro:   IPR006262
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: =3.5.4.5 [H]

Molecular weight: Translated: 14623; Mature: 14623

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
3.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKELIKKALEARELAYCPYSNFKVGAAALFEDGKIYTGCNIENASFGATNCAERTAIFK
CCHHHHHHHHHHHHHCCCCCCCCCCCHHEEECCCCEEECCCCCCCCCCCCCHHHHHHHHH
GVSEGARVLKAMALVGDLNSYTYPCGICRQVIVEFAEDKDIKIFIVKSEDDYIETTLDEI
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHH
LPGSFTKKDLEK
CCCCCCHHHCCC
>Mature Secondary Structure
MKKELIKKALEARELAYCPYSNFKVGAAALFEDGKIYTGCNIENASFGATNCAERTAIFK
CCHHHHHHHHHHHHHCCCCCCCCCCCHHEEECCCCEEECCCCCCCCCCCCCHHHHHHHHH
GVSEGARVLKAMALVGDLNSYTYPCGICRQVIVEFAEDKDIKIFIVKSEDDYIETTLDEI
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHH
LPGSFTKKDLEK
CCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11739901 [H]