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The map label for this gene is 18310979

Identifier: 18310979

GI number: 18310979

Start: 2287837

End: 2289072

Strand: Direct

Name: 18310979

Synonym: CPE1997

Alternate gene names: NA

Gene position: 2287837-2289072 (Clockwise)

Preceding gene: 18310978

Following gene: 18310992

Centisome position: 75.47

GC content: 31.07

Gene sequence:

>1236_bases
ATGAACAAATTTGAAAGCATGTTAGAAAATTATGCAAAGTTAGCTACTCATATAGGAGTAAATGTTCAAGAGGGTCAAAC
CCTTGTTATATCTTCTCCTGTAGAATGTGCAGAATTTACAAGAATGCTTGTTAAATCTGCTTATGAAAAAGGAGCAAAGG
ATGTTGTTGTTCAATGGAATGATGAAATATGCGGCAAAATTAAATATGAACACTCTCCATTAGAAGTTTTTGAAAACTTC
CCAGATTGGATGAAAGAATCAAGATTAAGCTATGCTAAAGAAGGAGCTTGCTTCTTAAGTATTTCTGCCTCTGATCCTGA
ACTTCTAAAAAATATAGACCCTGCAAAAATAGCAGCCTTTAGAAAATCATCAAGTACAGCTTTAAAAGAATTTAGTGAAA
TGTTAATGAGCAATAAAAATGCATGGTCAATAGTTTCTATTCCAACTAAAGCTTGGGCTAAAAAAGTTTTTTCTGATTTA
CCTGAAGAAGAAGCAGTAGATAAATTATGGAATGAAATCTTTAAAATAGTTAGAGTTGATACAGAGAACCCTGTTGAAGC
TTGGAATAAACATAAAGAAACTTTAAAATACCATATGGATTACTTAAATGAAAAGAATCTAAAATCACTTCATTTTGAAA
ATTCACTTGGAACTGATTTAACTATAGAATTACCAGAAAATCATCTTTGGGCTGGTGGAGCTGAATATACTCAAGGTGGG
GTTGAATTCATAGCTAATATGCCTACTGAGGAAGTATTCTCTATGCCTTCTAAATTTGGAGTTAATGGAACAGTATTTAG
TTCTAAACCTTTAAACTACGGTGGAAATTTAATAGATAATTTCTCAGTTACTTTTAAAGATGGAAAAGTTGTTGATTTCT
CAGCTGAAAAAGGATACGATACTTTAAAACATCTTTTAGATACTGATGAAGGTGCTAAATATTTAGGAGAAGTTGCTCTT
GTTCCTTATAATTCTCCTATATCAAACTCAGGAATAATTTTCTTCAACACTCTATATGATGAAAATGCTTCTTGTCATTT
AGCTTTTGGTAAAGCATATTCTCTATGCATAAAAAATGGTGAAAATATGACTAATGAAGAGCTTGAAAAAGCTGGAGCTA
ATGATTCATTAACTCATGTAGATTTCATGATAGGAACTAAAGATTTAAAAATCACAGGTTTAACTCATGATAATGTTGAA
ATTCCAGTATTTAAAGATGGTAACTGGGCATTTTAA

Upstream 100 bases:

>100_bases
ACAAATGGACTTTTATAAAATAATCTTTATTAATTAATTGTTTTATAAATTTTACTGCATTATAATAATGGTAAGAATTT
GTAAAGAAAGGACTGATATT

Downstream 100 bases:

>100_bases
TATCTAAAAATATATTTTAAATATATGATTAGATTAAACCTTCAAAAAATAAACACATGTTTTAAATCCATATTTATTTT
TAAATATAATTTTAAAAACA

Product: aminopeptidase

Products: NA

Alternate protein names: Aminopeptidase II; AP-II [H]

Number of amino acids: Translated: 411; Mature: 411

Protein sequence:

>411_residues
MNKFESMLENYAKLATHIGVNVQEGQTLVISSPVECAEFTRMLVKSAYEKGAKDVVVQWNDEICGKIKYEHSPLEVFENF
PDWMKESRLSYAKEGACFLSISASDPELLKNIDPAKIAAFRKSSSTALKEFSEMLMSNKNAWSIVSIPTKAWAKKVFSDL
PEEEAVDKLWNEIFKIVRVDTENPVEAWNKHKETLKYHMDYLNEKNLKSLHFENSLGTDLTIELPENHLWAGGAEYTQGG
VEFIANMPTEEVFSMPSKFGVNGTVFSSKPLNYGGNLIDNFSVTFKDGKVVDFSAEKGYDTLKHLLDTDEGAKYLGEVAL
VPYNSPISNSGIIFFNTLYDENASCHLAFGKAYSLCIKNGENMTNEELEKAGANDSLTHVDFMIGTKDLKITGLTHDNVE
IPVFKDGNWAF

Sequences:

>Translated_411_residues
MNKFESMLENYAKLATHIGVNVQEGQTLVISSPVECAEFTRMLVKSAYEKGAKDVVVQWNDEICGKIKYEHSPLEVFENF
PDWMKESRLSYAKEGACFLSISASDPELLKNIDPAKIAAFRKSSSTALKEFSEMLMSNKNAWSIVSIPTKAWAKKVFSDL
PEEEAVDKLWNEIFKIVRVDTENPVEAWNKHKETLKYHMDYLNEKNLKSLHFENSLGTDLTIELPENHLWAGGAEYTQGG
VEFIANMPTEEVFSMPSKFGVNGTVFSSKPLNYGGNLIDNFSVTFKDGKVVDFSAEKGYDTLKHLLDTDEGAKYLGEVAL
VPYNSPISNSGIIFFNTLYDENASCHLAFGKAYSLCIKNGENMTNEELEKAGANDSLTHVDFMIGTKDLKITGLTHDNVE
IPVFKDGNWAF
>Mature_411_residues
MNKFESMLENYAKLATHIGVNVQEGQTLVISSPVECAEFTRMLVKSAYEKGAKDVVVQWNDEICGKIKYEHSPLEVFENF
PDWMKESRLSYAKEGACFLSISASDPELLKNIDPAKIAAFRKSSSTALKEFSEMLMSNKNAWSIVSIPTKAWAKKVFSDL
PEEEAVDKLWNEIFKIVRVDTENPVEAWNKHKETLKYHMDYLNEKNLKSLHFENSLGTDLTIELPENHLWAGGAEYTQGG
VEFIANMPTEEVFSMPSKFGVNGTVFSSKPLNYGGNLIDNFSVTFKDGKVVDFSAEKGYDTLKHLLDTDEGAKYLGEVAL
VPYNSPISNSGIIFFNTLYDENASCHLAFGKAYSLCIKNGENMTNEELEKAGANDSLTHVDFMIGTKDLKITGLTHDNVE
IPVFKDGNWAF

Specific function: Broad specificity metal-dependent exopeptidase, releasing all N-terminal amino acids [H]

COG id: COG2309

COG function: function code E; Leucyl aminopeptidase (aminopeptidase T)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M29 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000787 [H]

Pfam domain/function: PF02073 Peptidase_M29 [H]

EC number: NA

Molecular weight: Translated: 46082; Mature: 46082

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKFESMLENYAKLATHIGVNVQEGQTLVISSPVECAEFTRMLVKSAYEKGAKDVVVQWN
CCHHHHHHHHHHHHHHHCCCEECCCCEEEEECCCHHHHHHHHHHHHHHHCCCCEEEEEEC
DEICGKIKYEHSPLEVFENFPDWMKESRLSYAKEGACFLSISASDPELLKNIDPAKIAAF
CCCCCEEEECCCHHHHHHCCHHHHHHHHHHHHCCCCEEEEEECCCHHHHHCCCHHHHHHH
RKSSSTALKEFSEMLMSNKNAWSIVSIPTKAWAKKVFSDLPEEEAVDKLWNEIFKIVRVD
HCCCHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHCCHHHHHHHHHHHHHHHEECC
TENPVEAWNKHKETLKYHMDYLNEKNLKSLHFENSLGTDLTIELPENHLWAGGAEYTQGG
CCCHHHHHHHHHHHHHHHHHHCCCCCCHHEEECCCCCCCEEEECCCCCEECCCCHHHHHH
VEFIANMPTEEVFSMPSKFGVNGTVFSSKPLNYGGNLIDNFSVTFKDGKVVDFSAEKGYD
HHHHHCCCHHHHHCCCHHCCCCEEEECCCCCCCCCCEEECCEEEEECCEEEEECCCCCHH
TLKHLLDTDEGAKYLGEVALVPYNSPISNSGIIFFNTLYDENASCHLAFGKAYSLCIKNG
HHHHHHCCCCCHHHHCCEEEEECCCCCCCCCEEEEEEEECCCCEEEEEECCEEEEEECCC
ENMTNEELEKAGANDSLTHVDFMIGTKDLKITGLTHDNVEIPVFKDGNWAF
CCCCHHHHHHCCCCCCCEEEEEEEECCCEEEEEECCCCEEEEEEECCCCCC
>Mature Secondary Structure
MNKFESMLENYAKLATHIGVNVQEGQTLVISSPVECAEFTRMLVKSAYEKGAKDVVVQWN
CCHHHHHHHHHHHHHHHCCCEECCCCEEEEECCCHHHHHHHHHHHHHHHCCCCEEEEEEC
DEICGKIKYEHSPLEVFENFPDWMKESRLSYAKEGACFLSISASDPELLKNIDPAKIAAF
CCCCCEEEECCCHHHHHHCCHHHHHHHHHHHHCCCCEEEEEECCCHHHHHCCCHHHHHHH
RKSSSTALKEFSEMLMSNKNAWSIVSIPTKAWAKKVFSDLPEEEAVDKLWNEIFKIVRVD
HCCCHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHCCHHHHHHHHHHHHHHHEECC
TENPVEAWNKHKETLKYHMDYLNEKNLKSLHFENSLGTDLTIELPENHLWAGGAEYTQGG
CCCHHHHHHHHHHHHHHHHHHCCCCCCHHEEECCCCCCCEEEECCCCCEECCCCHHHHHH
VEFIANMPTEEVFSMPSKFGVNGTVFSSKPLNYGGNLIDNFSVTFKDGKVVDFSAEKGYD
HHHHHCCCHHHHHCCCHHCCCCEEEECCCCCCCCCCEEECCEEEEECCEEEEECCCCCHH
TLKHLLDTDEGAKYLGEVALVPYNSPISNSGIIFFNTLYDENASCHLAFGKAYSLCIKNG
HHHHHHCCCCCHHHHCCEEEEECCCCCCCCCEEEEEEEECCCCEEEEEECCEEEEEECCC
ENMTNEELEKAGANDSLTHVDFMIGTKDLKITGLTHDNVEIPVFKDGNWAF
CCCCHHHHHHCCCCCCCEEEEEEEECCCEEEEEECCCCEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9362117; 938681 [H]