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The map label for this gene is ruvA [H]

Identifier: 18310930

GI number: 18310930

Start: 2231145

End: 2231750

Strand: Reverse

Name: ruvA [H]

Synonym: CPE1948

Alternate gene names: 18310930

Gene position: 2231750-2231145 (Counterclockwise)

Preceding gene: 18310931

Following gene: 18310929

Centisome position: 73.62

GC content: 29.7

Gene sequence:

>606_bases
ATGTACGAATATATAAGAGGCCAATTTCAAGGGATAAGTAAGGATTATGTTGTAATAGAATTAAATAATATAGGATATAA
AATTTTCACATCTGGAAATACAATGTCTAATATGCCAAAAGTGGGAGATGAAGTTCTTCTATATCTAGAGCAGATCGTTA
GAGAAGATTTCATAGGTCTATATGGATTTACAACAAGAGAAGAATTAGAAATGTTTAAGCTTTTATTATCCATAAATGGA
GTAGGAGCAAAAGCTGCTTTATCACTTTTATCCATTAGTACTGTTAATAATTTAAAGTACGCAATAATGATGGGAGATGA
AAAGCATATAACAAGAGCACCTGGAATAGGAAAGAAAACGGCTCAAAGAATTATTCTAGAGCTTAAGGATAAGTTAAAAC
CAGATGAACTTACTTCTGAAGAGGGACAATTAATAGAAGGAATTAATGATAATTCTGATTATAGTTTCAATATAAATGAA
ACATTAAGTGCCTTAATGGCATTAGGATATACAGAGAAGGAAGCTCAAAAAGCTTTAGAAAAAGTTGATAAGACATTATC
TATAGAAAATATGATAAAGGAGTCTTTAAAACTTTTAATGCGTTAG

Upstream 100 bases:

>100_bases
AATGAATAGTAAATTTTGTGTAATTCATTGATAATATTCCCTCTTCATGTTAAAGTATTATATAGATTTAAAGAACTTAT
TATACATAGGAGCATTAAAT

Downstream 100 bases:

>100_bases
GAGGTGTAATTAAATGAGTGAAAGATTAGTTACCTCTAATGAGATTGGAATAGATTCAACTAATGAATACAGTTTGAGAC
CAGAGAAAATAAATGAATAT

Product: Holliday junction DNA helicase RuvA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 201; Mature: 201

Protein sequence:

>201_residues
MYEYIRGQFQGISKDYVVIELNNIGYKIFTSGNTMSNMPKVGDEVLLYLEQIVREDFIGLYGFTTREELEMFKLLLSING
VGAKAALSLLSISTVNNLKYAIMMGDEKHITRAPGIGKKTAQRIILELKDKLKPDELTSEEGQLIEGINDNSDYSFNINE
TLSALMALGYTEKEAQKALEKVDKTLSIENMIKESLKLLMR

Sequences:

>Translated_201_residues
MYEYIRGQFQGISKDYVVIELNNIGYKIFTSGNTMSNMPKVGDEVLLYLEQIVREDFIGLYGFTTREELEMFKLLLSING
VGAKAALSLLSISTVNNLKYAIMMGDEKHITRAPGIGKKTAQRIILELKDKLKPDELTSEEGQLIEGINDNSDYSFNINE
TLSALMALGYTEKEAQKALEKVDKTLSIENMIKESLKLLMR
>Mature_201_residues
MYEYIRGQFQGISKDYVVIELNNIGYKIFTSGNTMSNMPKVGDEVLLYLEQIVREDFIGLYGFTTREELEMFKLLLSING
VGAKAALSLLSISTVNNLKYAIMMGDEKHITRAPGIGKKTAQRIILELKDKLKPDELTSEEGQLIEGINDNSDYSFNINE
TLSALMALGYTEKEAQKALEKVDKTLSIENMIKESLKLLMR

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family [H]

Homologues:

Organism=Escherichia coli, GI1788168, Length=198, Percent_Identity=32.3232323232323, Blast_Score=108, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011114
- InterPro:   IPR013849
- InterPro:   IPR003583
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994 [H]

Pfam domain/function: PF07499 RuvA_C; PF01330 RuvA_N [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 22676; Mature: 22676

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYEYIRGQFQGISKDYVVIELNNIGYKIFTSGNTMSNMPKVGDEVLLYLEQIVREDFIGL
CCCHHHHHHCCCCCCEEEEEECCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
YGFTTREELEMFKLLLSINGVGAKAALSLLSISTVNNLKYAIMMGDEKHITRAPGIGKKT
CCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCCHHH
AQRIILELKDKLKPDELTSEEGQLIEGINDNSDYSFNINETLSALMALGYTEKEAQKALE
HHHHHHHHHHCCCCCCCCCCCCCEECCCCCCCCEEEEHHHHHHHHHHHCCCHHHHHHHHH
KVDKTLSIENMIKESLKLLMR
HHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MYEYIRGQFQGISKDYVVIELNNIGYKIFTSGNTMSNMPKVGDEVLLYLEQIVREDFIGL
CCCHHHHHHCCCCCCEEEEEECCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
YGFTTREELEMFKLLLSINGVGAKAALSLLSISTVNNLKYAIMMGDEKHITRAPGIGKKT
CCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCCHHH
AQRIILELKDKLKPDELTSEEGQLIEGINDNSDYSFNINETLSALMALGYTEKEAQKALE
HHHHHHHHHHCCCCCCCCCCCCCEECCCCCCCCEEEEHHHHHHHHHHHCCCHHHHHHHHH
KVDKTLSIENMIKESLKLLMR
HHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA