Click here to switch to the map view.

The map label for this gene is ruvB [H]

Identifier: 18310929

GI number: 18310929

Start: 2230091

End: 2231131

Strand: Reverse

Name: ruvB [H]

Synonym: CPE1947

Alternate gene names: 18310929

Gene position: 2231131-2230091 (Counterclockwise)

Preceding gene: 18310930

Following gene: 18310928

Centisome position: 73.6

GC content: 32.95

Gene sequence:

>1041_bases
ATGAGTGAAAGATTAGTTACCTCTAATGAGATTGGAATAGATTCAACTAATGAATACAGTTTGAGACCAGAGAAAATAAA
TGAATATATAGGGCAAGACAAAGTTAAAGAAAGATTAAACATATTCATAAAAGCTGCTCAAAGAAGAGAGGAAGCCTTAG
ACCATGTAATTTTATATGGACCACCAGGTCTTGGAAAGACAACATTAGCTAATATAATAGCAAATGAAATGGGTGGAAAT
CTTAAAATAACATCAGGGCCTGCTATTGAAAGAGCAGGAGACTTAGCGGCAATATTAACAACCTTAAACACTAATGATGT
TCTGTTTATTGATGAGATACATAGATTAAATAGAAGTGTAGAGGAAATACTATATCCTGCCATGGAAGATTATGTTTTAG
ACATAATTATTGGTAAGGGAGCTGCTAGTAAATCCATAAGACTCGATTTACCTAAATTTACTCTAATAGGTGCCACAACT
AGAATTGGTATGCTTAGTTCACCTTTAAGAGATAGATTGGGGGTTTTATGTTCTATGGAATATTATACTGATGAGCAATT
AAAGGAAATAATAATTAGAAGTGCTGAAATTTTAGGATGCCATATAACTGAAGAGGGGGCCTTTGAAATTGCTAAAAGGT
CAAGGGGTACTCCTAGAATAGCAAATAGACTTTTAAAGAGAGTGAGAGATTTTGCAGAAGTTTTATATGATAATGAAATT
ACAGAAGAGGCTGCAAAAAAATCCTTAGAGATTTTAGAAGTTGATGGAGAAGGCTTTGATAGAATTGACAATAAAATTCT
AGAAGCCATAATAGATAACTTCAATGGAGGACCAGTAGGGATAGAAACCTTAGCTTACTTCGTTGGAGAGGAATTAGATA
CTATAGAAGATGTTTATGAGCCATATCTTCTACAAAAAGGGTTTATAGTTAGAACTCCAAGGGGAAGAATGGCAACAGAT
AAAGCATATAAACACTTAGGAAGAGTTAGATTTAATGAATCTAAGATAGATTCTAAACAGTGTACGTTATTTGAAAAATA
A

Upstream 100 bases:

>100_bases
GAAGCTCAAAAAGCTTTAGAAAAAGTTGATAAGACATTATCTATAGAAAATATGATAAAGGAGTCTTTAAAACTTTTAAT
GCGTTAGGAGGTGTAATTAA

Downstream 100 bases:

>100_bases
AATAGAGAAGGTGTAATTAAAATGAAAGTAAGTGATTTTTATTTTGAGCTACCAGAAGAACTTATAGCTCAATATCCACT
TGAAAAGAGAGATTCTTCAA

Product: Holliday junction DNA helicase RuvB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 346; Mature: 345

Protein sequence:

>346_residues
MSERLVTSNEIGIDSTNEYSLRPEKINEYIGQDKVKERLNIFIKAAQRREEALDHVILYGPPGLGKTTLANIIANEMGGN
LKITSGPAIERAGDLAAILTTLNTNDVLFIDEIHRLNRSVEEILYPAMEDYVLDIIIGKGAASKSIRLDLPKFTLIGATT
RIGMLSSPLRDRLGVLCSMEYYTDEQLKEIIIRSAEILGCHITEEGAFEIAKRSRGTPRIANRLLKRVRDFAEVLYDNEI
TEEAAKKSLEILEVDGEGFDRIDNKILEAIIDNFNGGPVGIETLAYFVGEELDTIEDVYEPYLLQKGFIVRTPRGRMATD
KAYKHLGRVRFNESKIDSKQCTLFEK

Sequences:

>Translated_346_residues
MSERLVTSNEIGIDSTNEYSLRPEKINEYIGQDKVKERLNIFIKAAQRREEALDHVILYGPPGLGKTTLANIIANEMGGN
LKITSGPAIERAGDLAAILTTLNTNDVLFIDEIHRLNRSVEEILYPAMEDYVLDIIIGKGAASKSIRLDLPKFTLIGATT
RIGMLSSPLRDRLGVLCSMEYYTDEQLKEIIIRSAEILGCHITEEGAFEIAKRSRGTPRIANRLLKRVRDFAEVLYDNEI
TEEAAKKSLEILEVDGEGFDRIDNKILEAIIDNFNGGPVGIETLAYFVGEELDTIEDVYEPYLLQKGFIVRTPRGRMATD
KAYKHLGRVRFNESKIDSKQCTLFEK
>Mature_345_residues
SERLVTSNEIGIDSTNEYSLRPEKINEYIGQDKVKERLNIFIKAAQRREEALDHVILYGPPGLGKTTLANIIANEMGGNL
KITSGPAIERAGDLAAILTTLNTNDVLFIDEIHRLNRSVEEILYPAMEDYVLDIIIGKGAASKSIRLDLPKFTLIGATTR
IGMLSSPLRDRLGVLCSMEYYTDEQLKEIIIRSAEILGCHITEEGAFEIAKRSRGTPRIANRLLKRVRDFAEVLYDNEIT
EEAAKKSLEILEVDGEGFDRIDNKILEAIIDNFNGGPVGIETLAYFVGEELDTIEDVYEPYLLQKGFIVRTPRGRMATDK
AYKHLGRVRFNESKIDSKQCTLFEK

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG2255

COG function: function code L; Holliday junction resolvasome, helicase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvB family [H]

Homologues:

Organism=Escherichia coli, GI1788167, Length=326, Percent_Identity=58.2822085889571, Blast_Score=412, Evalue=1e-116,
Organism=Escherichia coli, GI1787119, Length=270, Percent_Identity=31.1111111111111, Blast_Score=73, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR004605
- InterPro:   IPR008823
- InterPro:   IPR008824
- InterPro:   IPR011991
- ProDom:   PD005323 [H]

Pfam domain/function: PF05491 RuvB_C; PF05496 RuvB_N [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 38902; Mature: 38771

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSERLVTSNEIGIDSTNEYSLRPEKINEYIGQDKVKERLNIFIKAAQRREEALDHVILYG
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCEEEEEC
PPGLGKTTLANIIANEMGGNLKITSGPAIERAGDLAAILTTLNTNDVLFIDEIHRLNRSV
CCCCCHHHHHHHHHHHCCCCEEECCCCCHHHHCCHHHHHHCCCCCCEEEHHHHHHHHHHH
EEILYPAMEDYVLDIIIGKGAASKSIRLDLPKFTLIGATTRIGMLSSPLRDRLGVLCSME
HHHHHHHHHHHEEEEEEECCCCCCCEEEECCCEEEEECHHHHHHHHHHHHHHHHHEEEEH
YYTDEQLKEIIIRSAEILGCHITEEGAFEIAKRSRGTPRIANRLLKRVRDFAEVLYDNEI
HHCHHHHHHHHHHHHHHEEEEECCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHH
TEEAAKKSLEILEVDGEGFDRIDNKILEAIIDNFNGGPVGIETLAYFVGEELDTIEDVYE
HHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHHHHH
PYLLQKGFIVRTPRGRMATDKAYKHLGRVRFNESKIDSKQCTLFEK
HHHHCCCCEEECCCCCCHHHHHHHHHHHCCCCHHHCCCCCCCCCCC
>Mature Secondary Structure 
SERLVTSNEIGIDSTNEYSLRPEKINEYIGQDKVKERLNIFIKAAQRREEALDHVILYG
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCEEEEEC
PPGLGKTTLANIIANEMGGNLKITSGPAIERAGDLAAILTTLNTNDVLFIDEIHRLNRSV
CCCCCHHHHHHHHHHHCCCCEEECCCCCHHHHCCHHHHHHCCCCCCEEEHHHHHHHHHHH
EEILYPAMEDYVLDIIIGKGAASKSIRLDLPKFTLIGATTRIGMLSSPLRDRLGVLCSME
HHHHHHHHHHHEEEEEEECCCCCCCEEEECCCEEEEECHHHHHHHHHHHHHHHHHEEEEH
YYTDEQLKEIIIRSAEILGCHITEEGAFEIAKRSRGTPRIANRLLKRVRDFAEVLYDNEI
HHCHHHHHHHHHHHHHHEEEEECCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHH
TEEAAKKSLEILEVDGEGFDRIDNKILEAIIDNFNGGPVGIETLAYFVGEELDTIEDVYE
HHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHHHHH
PYLLQKGFIVRTPRGRMATDKAYKHLGRVRFNESKIDSKQCTLFEK
HHHHCCCCEEECCCCCCHHHHHHHHHHHCCCCHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA