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The map label for this gene is hlyE [C]

Identifier: 18310897

GI number: 18310897

Start: 2193942

End: 2194583

Strand: Reverse

Name: hlyE [C]

Synonym: CPE1915

Alternate gene names: 18310897

Gene position: 2194583-2193942 (Counterclockwise)

Preceding gene: 18310899

Following gene: 18310893

Centisome position: 72.39

GC content: 28.19

Gene sequence:

>642_bases
GTGAGTGAAGAATTAAATTTTTATACTAGAGAAGAGGAATTTGCTAATGCCATAACCCACGGAATTGGAGTGGTATTAGC
CATAGTGGGAGCTGTTTTACTTATAGTTTTCTCATCTTTAAGTAGAGATGTTTATAAGATAATAAGCTTCACTATATTTG
GAATAACTTTATTTTTACTTTATTTAGGATCAACATTATATCATAGTATTCCTAATAAAAAAGTAAAGAGGTTTTTAAGG
ATAATTGACCATTCATCTATTTATCTTTTAATAGCAGGAACTTATACACCTTATGTATTAGTATGTTTAAGAGATAATAA
AAAAGCTATGGCAATATTTATTATGATTTGGGTAATTACCATATTAGGAATAGTATTTAAATTTATCTGTATAAATAAGT
TTGAGAATCTATCAACCTTATTATATATTTTTATGGGGTGGTCAGTTATCTTTGTAGTTAAGGATGTATGGCAAAGAGTA
CCTCATATGGCCGTCTTTTGGCTTCTTATAGGTGGATTGTTTTATACCTTAGGATGTATATTTTTTGTTTTAGATAGAAT
GCCATACAATCATGCTATCTGGCATTTATTTGTAATGGGAGGAAGCATAAGTCACTTTTTCTCTGTAATATTATATTTAT
AA

Upstream 100 bases:

>100_bases
TTTCTAAACATGTTTAATCATAAATCATAAATAGTATAATTACAAATATAAATTTAAAATATGCATATAATAACATGAGA
AAGGAAGGGGGACGGTAATT

Downstream 100 bases:

>100_bases
TAACAAAGAAGAAGCTATATAGAATCTAATTTATTAGTTCTATATAGCTCTTTATTAATTTCCTTCAGTATTATTTTGAT
TATTACTATTTTCAGAAGAA

Product: hemolysin III

Products: NA

Alternate protein names: Hemolysin III; Hly-III [H]

Number of amino acids: Translated: 213; Mature: 212

Protein sequence:

>213_residues
MSEELNFYTREEEFANAITHGIGVVLAIVGAVLLIVFSSLSRDVYKIISFTIFGITLFLLYLGSTLYHSIPNKKVKRFLR
IIDHSSIYLLIAGTYTPYVLVCLRDNKKAMAIFIMIWVITILGIVFKFICINKFENLSTLLYIFMGWSVIFVVKDVWQRV
PHMAVFWLLIGGLFYTLGCIFFVLDRMPYNHAIWHLFVMGGSISHFFSVILYL

Sequences:

>Translated_213_residues
MSEELNFYTREEEFANAITHGIGVVLAIVGAVLLIVFSSLSRDVYKIISFTIFGITLFLLYLGSTLYHSIPNKKVKRFLR
IIDHSSIYLLIAGTYTPYVLVCLRDNKKAMAIFIMIWVITILGIVFKFICINKFENLSTLLYIFMGWSVIFVVKDVWQRV
PHMAVFWLLIGGLFYTLGCIFFVLDRMPYNHAIWHLFVMGGSISHFFSVILYL
>Mature_212_residues
SEELNFYTREEEFANAITHGIGVVLAIVGAVLLIVFSSLSRDVYKIISFTIFGITLFLLYLGSTLYHSIPNKKVKRFLRI
IDHSSIYLLIAGTYTPYVLVCLRDNKKAMAIFIMIWVITILGIVFKFICINKFENLSTLLYIFMGWSVIFVVKDVWQRVP
HMAVFWLLIGGLFYTLGCIFFVLDRMPYNHAIWHLFVMGGSISHFFSVILYL

Specific function: Unknown

COG id: COG1272

COG function: function code R; Predicted membrane protein, hemolysin III homolog

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0073 (Hly-III) family [H]

Homologues:

Organism=Homo sapiens, GI154759275, Length=213, Percent_Identity=32.8638497652582, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI52630445, Length=209, Percent_Identity=33.0143540669856, Blast_Score=91, Evalue=8e-19,
Organism=Homo sapiens, GI154759277, Length=237, Percent_Identity=29.957805907173, Blast_Score=89, Evalue=3e-18,
Organism=Escherichia coli, GI1789266, Length=207, Percent_Identity=45.8937198067633, Blast_Score=190, Evalue=7e-50,
Organism=Caenorhabditis elegans, GI71996356, Length=221, Percent_Identity=33.4841628959276, Blast_Score=101, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24640324, Length=230, Percent_Identity=30.4347826086957, Blast_Score=84, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004254
- InterPro:   IPR005744 [H]

Pfam domain/function: PF03006 HlyIII [H]

EC number: NA

Molecular weight: Translated: 24606; Mature: 24475

Theoretical pI: Translated: 9.26; Mature: 9.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEELNFYTREEEFANAITHGIGVVLAIVGAVLLIVFSSLSRDVYKIISFTIFGITLFLL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YLGSTLYHSIPNKKVKRFLRIIDHSSIYLLIAGTYTPYVLVCLRDNKKAMAIFIMIWVIT
HHHHHHHHHCCCHHHHHHHHHHCCCCEEEEEEECCCCEEEEEEECCCHHHHHHHHHHHHH
ILGIVFKFICINKFENLSTLLYIFMGWSVIFVVKDVWQRVPHMAVFWLLIGGLFYTLGCI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FFVLDRMPYNHAIWHLFVMGGSISHFFSVILYL
HHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHCC
>Mature Secondary Structure 
SEELNFYTREEEFANAITHGIGVVLAIVGAVLLIVFSSLSRDVYKIISFTIFGITLFLL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YLGSTLYHSIPNKKVKRFLRIIDHSSIYLLIAGTYTPYVLVCLRDNKKAMAIFIMIWVIT
HHHHHHHHHCCCHHHHHHHHHHCCCCEEEEEEECCCCEEEEEEECCCHHHHHHHHHHHHH
ILGIVFKFICINKFENLSTLLYIFMGWSVIFVVKDVWQRVPHMAVFWLLIGGLFYTLGCI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FFVLDRMPYNHAIWHLFVMGGSISHFFSVILYL
HHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7495855 [H]