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The map label for this gene is ntpK [H]

Identifier: 18310624

GI number: 18310624

Start: 1914185

End: 1914679

Strand: Reverse

Name: ntpK [H]

Synonym: CPE1642

Alternate gene names: 18310624

Gene position: 1914679-1914185 (Counterclockwise)

Preceding gene: 18310625

Following gene: 18310623

Centisome position: 63.16

GC content: 35.35

Gene sequence:

>495_bases
ATGGAAAACTGGATTTCATATTTTATGGCAAATTACGGAGGATTAATATTTGGAGCTTTTGGAATAGCATTAGCTGTAGG
TATGTCAGGTATAGGATCAGCTAAAGGTGTTGGTATAGTTGGGGAAGCAGCAGCGGGATTAGTTACTGAAGAACCAGAAA
AGTTTGGTAAAGCATTAGTTCTTGAATTATTACCAGGTACACAAGGTCTTTATGGATTCGTTATAGGTTTCTTAGTATTT
AACCAAATCAGTAATGGTGATGCATCATTAGCTAAAGGATTATACTTATTATTTGCTTGTTTACCAATAGCTATCGCTGG
ATTATGGTCAGGTATATCTCAAGGTAAAGCAGCTGCAGCTGGTATCCAAATCTTAGCTAAAAGACCAGAGCACAATACTA
AAGGTATCATATTCGCAGCAATGGTTGAAACATATGCATTATTAGGATTCGTTATATCATTCTTATTAGTAAATGGTGCA
AGCGTAATACAATAA

Upstream 100 bases:

>100_bases
ATTTAGAACAATAAATAAATTCATAACAATAAAAAGAAATAAATAAATTATAGTTAAAATTAAATTAAAATAACATTATA
TTTTCAGGAGGAATTAAATT

Downstream 100 bases:

>100_bases
TAGTAAGCAAAGATTGGAGAAGTGAAGGGAATGTCAAATTTAAATAATTTAACTTCCAAGATTCTAAATGATGCTGAAGA
AAAGAAAAAGTATATATTAG

Product: V-type ATP synthase subunit K

Products: ADP; phosphate; H+

Alternate protein names: Na(+)-translocating ATPase subunit K; Sodium ATPase proteolipid component [H]

Number of amino acids: Translated: 164; Mature: 164

Protein sequence:

>164_residues
MENWISYFMANYGGLIFGAFGIALAVGMSGIGSAKGVGIVGEAAAGLVTEEPEKFGKALVLELLPGTQGLYGFVIGFLVF
NQISNGDASLAKGLYLLFACLPIAIAGLWSGISQGKAAAAGIQILAKRPEHNTKGIIFAAMVETYALLGFVISFLLVNGA
SVIQ

Sequences:

>Translated_164_residues
MENWISYFMANYGGLIFGAFGIALAVGMSGIGSAKGVGIVGEAAAGLVTEEPEKFGKALVLELLPGTQGLYGFVIGFLVF
NQISNGDASLAKGLYLLFACLPIAIAGLWSGISQGKAAAAGIQILAKRPEHNTKGIIFAAMVETYALLGFVISFLLVNGA
SVIQ
>Mature_164_residues
MENWISYFMANYGGLIFGAFGIALAVGMSGIGSAKGVGIVGEAAAGLVTEEPEKFGKALVLELLPGTQGLYGFVIGFLVF
NQISNGDASLAKGLYLLFACLPIAIAGLWSGISQGKAAAAGIQILAKRPEHNTKGIIFAAMVETYALLGFVISFLLVNGA
SVIQ

Specific function: Involved in ATP-driven sodium extrusion [H]

COG id: COG0636

COG function: function code C; F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the V-ATPase proteolipid subunit family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002379
- InterPro:   IPR000245 [H]

Pfam domain/function: PF00137 ATP-synt_C [H]

EC number: 3.6.3.14

Molecular weight: Translated: 16919; Mature: 16919

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENWISYFMANYGGLIFGAFGIALAVGMSGIGSAKGVGIVGEAAAGLVTEEPEKFGKALV
CHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCCCCEEHHHHHCCCCCCHHHHHHHHH
LELLPGTQGLYGFVIGFLVFNQISNGDASLAKGLYLLFACLPIAIAGLWSGISQGKAAAA
HHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
GIQILAKRPEHNTKGIIFAAMVETYALLGFVISFLLVNGASVIQ
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHCC
>Mature Secondary Structure
MENWISYFMANYGGLIFGAFGIALAVGMSGIGSAKGVGIVGEAAAGLVTEEPEKFGKALV
CHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCCCCEEHHHHHCCCCCCHHHHHHHHH
LELLPGTQGLYGFVIGFLVFNQISNGDASLAKGLYLLFACLPIAIAGLWSGISQGKAAAA
HHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
GIQILAKRPEHNTKGIIFAAMVETYALLGFVISFLLVNGASVIQ
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8373385; 8157629; 8144530 [H]