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The map label for this gene is ntpI [H]

Identifier: 18310625

GI number: 18310625

Start: 1914734

End: 1916680

Strand: Reverse

Name: ntpI [H]

Synonym: CPE1643

Alternate gene names: 18310625

Gene position: 1916680-1914734 (Counterclockwise)

Preceding gene: 18310626

Following gene: 18310624

Centisome position: 63.23

GC content: 32.2

Gene sequence:

>1947_bases
ATGGCAATAGTTAAGATGAATAAATTCACCTTACTTGCCTTTGAATCAGAGAAAGAAAAGCTTCTTAAAAAAATTCAAAG
TTCTTCAGAAGTTGAGTTCATAAACTTACAAGATGAAGAAAAAGTGGAAGGCAATGAAGTCTTTGAATCTCTTAGCAAAG
ATGATTTAGATGCTGAAACAACTCTTATAGAAGAAAATGTTTCAAAAACAAGATCAGCTTTAGACTTCTTAAAAGAGTTT
GTTGCTGAAGTTGGAGGACTTAAGGCTTTAAAAGCTGGTAAAGAAAGCTTAACTTTGGATGAGCTAGAAGTAAAGGTTGA
AAATAGCAACTGGGAAGTCGTTTATTCAGAGGTTAAGAAAATGGAGAGAGAGCTTGCTACTCTAGAAAACGAAAAGACAA
AACTTTTAGGTGAAATAGAAATCTTAGAGCCATGGCAAAGTTTCGATGCTCCACTAGGTGAATTAAATAATTTTGAAAAA
GTAGTTGCGTTCTTAGGTGTGATTTCAAGTCAAAATCTTGAAAATATGAAGAACGAAATTGAAAGCGAATTCAAGGAAAG
TTATATAGAAGTTATTTCTAACACTGACCAAGATTCATATGTCTTTGTAATGACAATGAAAGAAAGAGCAGAAGAAATGG
ACGAAGTTTTAAAGAACTTTGGTTTTTCAGCGTTCCAAACTAAGTACAAAGAAAAAGCTTCAGTTCTTGTTGAAGAGTTT
AAATTAAAGATACAAGAAATCGAAGCTCAAAAATCAGACTTAAAAGGAGTACTTTCAAATTACAGAGAAGAAAAGAGAAC
TTTAGAACTAGCTTATGAATATTACAGCAACATACTTCTTAGAAAAGAAGCAAGTGAAAACTTCTTAAAAACAGATAGAG
TAGTTGTTATTCAAGGGTGGGTTCCTAAAAATGATAATTCTTCTTTAGAAGGAATCATACAAAGTTCAGTAGGAGATATG
TATTATCTTGAGTTTGAAGAAGTTAAGGAAGAAGAGGTTGCAGAAGTTCCAGTTAAATTACACAATAAGGGACCAGCAGC
AGCTTTCGATTCAATAACAGAAATGTATAGCTTACCAAGATATGATGAAATAGACCCTACACCACTTTTAACACCTTTCT
ACCTAGTATTCTTCGGCATGATGGTTGCAGATTTAGGATACGGACTAGTATTATTTGTAGGATCACTATTAGCTATGAAA
TTACTTAATTTAGATGAGGCACAAGAAAAGTTTGCTAAATTCTTTATGTATTTAAGTATAGCTACAACTATTGCAGGTGC
AATATTTGGTACTGCCTTTGGATTTGAATTGAAATTTGGACTTATAAATCCAAGTAAAGATACCAACTTGTTACTAATTT
TATCAGTTGGATTTGGGGTTATTCAAATATTCTTTGGATTATTTATAAAAGCGTACATGTTAATCAGAGATAAGCAATAT
TTATATGCTTTATTTGATGTAGGATCATGGATTATGCTTTTAATAGGTCTTCCAATGATATTCTTTGATGGTCCTATAAG
CTTAGTAGGTAAAGTATTAGCAATAGTAGGTTCAATATTAATAATCTTAACACAAGGTAGAGATGAAGAAACAAAAGGTG
CTCAAATAGGTCAAGGTTTATATGCCTTATACGGTATAACAGGATACGTAGGAGACTTAGTATCATATACAAGACTTATG
GCTTTAGGTATTGCAGGTGGATCAATAGCCGCTGCACTTAACCTAATAATAGGTATGTTCCCAGGAATAGCAGTTATAAT
TGTAGGACCTCTATTCTTTATAGCAGCTCATACATTTAACATGCTTTTATCATTACTTGGAGCATATGTTCATACAGCGA
GATTACAGTACGTTGAGTACTTCTCAAAATTCTATGAAGGTGGCGGAAAAGCATTCACACCATTTAGAACAATAAATAAA
TTCATAACAATAAAAAGAAATAAATAA

Upstream 100 bases:

>100_bases
CTTTCAGAAGGTGAAAAACAATGTGCTGAGGTATCAAGTCTTAAAGGTTCTAAGATTGATTCAGCAGTAAATTTAGTTAT
TGAGAGGATTGTGAAAACTA

Downstream 100 bases:

>100_bases
ATTATAGTTAAAATTAAATTAAAATAACATTATATTTTCAGGAGGAATTAAATTATGGAAAACTGGATTTCATATTTTAT
GGCAAATTACGGAGGATTAA

Product: V-type ATP synthase subunit I

Products: ADP; phosphate; H+

Alternate protein names: Na(+)-translocating ATPase subunit I; V-type sodium pump subunit I [H]

Number of amino acids: Translated: 648; Mature: 647

Protein sequence:

>648_residues
MAIVKMNKFTLLAFESEKEKLLKKIQSSSEVEFINLQDEEKVEGNEVFESLSKDDLDAETTLIEENVSKTRSALDFLKEF
VAEVGGLKALKAGKESLTLDELEVKVENSNWEVVYSEVKKMERELATLENEKTKLLGEIEILEPWQSFDAPLGELNNFEK
VVAFLGVISSQNLENMKNEIESEFKESYIEVISNTDQDSYVFVMTMKERAEEMDEVLKNFGFSAFQTKYKEKASVLVEEF
KLKIQEIEAQKSDLKGVLSNYREEKRTLELAYEYYSNILLRKEASENFLKTDRVVVIQGWVPKNDNSSLEGIIQSSVGDM
YYLEFEEVKEEEVAEVPVKLHNKGPAAAFDSITEMYSLPRYDEIDPTPLLTPFYLVFFGMMVADLGYGLVLFVGSLLAMK
LLNLDEAQEKFAKFFMYLSIATTIAGAIFGTAFGFELKFGLINPSKDTNLLLILSVGFGVIQIFFGLFIKAYMLIRDKQY
LYALFDVGSWIMLLIGLPMIFFDGPISLVGKVLAIVGSILIILTQGRDEETKGAQIGQGLYALYGITGYVGDLVSYTRLM
ALGIAGGSIAAALNLIIGMFPGIAVIIVGPLFFIAAHTFNMLLSLLGAYVHTARLQYVEYFSKFYEGGGKAFTPFRTINK
FITIKRNK

Sequences:

>Translated_648_residues
MAIVKMNKFTLLAFESEKEKLLKKIQSSSEVEFINLQDEEKVEGNEVFESLSKDDLDAETTLIEENVSKTRSALDFLKEF
VAEVGGLKALKAGKESLTLDELEVKVENSNWEVVYSEVKKMERELATLENEKTKLLGEIEILEPWQSFDAPLGELNNFEK
VVAFLGVISSQNLENMKNEIESEFKESYIEVISNTDQDSYVFVMTMKERAEEMDEVLKNFGFSAFQTKYKEKASVLVEEF
KLKIQEIEAQKSDLKGVLSNYREEKRTLELAYEYYSNILLRKEASENFLKTDRVVVIQGWVPKNDNSSLEGIIQSSVGDM
YYLEFEEVKEEEVAEVPVKLHNKGPAAAFDSITEMYSLPRYDEIDPTPLLTPFYLVFFGMMVADLGYGLVLFVGSLLAMK
LLNLDEAQEKFAKFFMYLSIATTIAGAIFGTAFGFELKFGLINPSKDTNLLLILSVGFGVIQIFFGLFIKAYMLIRDKQY
LYALFDVGSWIMLLIGLPMIFFDGPISLVGKVLAIVGSILIILTQGRDEETKGAQIGQGLYALYGITGYVGDLVSYTRLM
ALGIAGGSIAAALNLIIGMFPGIAVIIVGPLFFIAAHTFNMLLSLLGAYVHTARLQYVEYFSKFYEGGGKAFTPFRTINK
FITIKRNK
>Mature_647_residues
AIVKMNKFTLLAFESEKEKLLKKIQSSSEVEFINLQDEEKVEGNEVFESLSKDDLDAETTLIEENVSKTRSALDFLKEFV
AEVGGLKALKAGKESLTLDELEVKVENSNWEVVYSEVKKMERELATLENEKTKLLGEIEILEPWQSFDAPLGELNNFEKV
VAFLGVISSQNLENMKNEIESEFKESYIEVISNTDQDSYVFVMTMKERAEEMDEVLKNFGFSAFQTKYKEKASVLVEEFK
LKIQEIEAQKSDLKGVLSNYREEKRTLELAYEYYSNILLRKEASENFLKTDRVVVIQGWVPKNDNSSLEGIIQSSVGDMY
YLEFEEVKEEEVAEVPVKLHNKGPAAAFDSITEMYSLPRYDEIDPTPLLTPFYLVFFGMMVADLGYGLVLFVGSLLAMKL
LNLDEAQEKFAKFFMYLSIATTIAGAIFGTAFGFELKFGLINPSKDTNLLLILSVGFGVIQIFFGLFIKAYMLIRDKQYL
YALFDVGSWIMLLIGLPMIFFDGPISLVGKVLAIVGSILIILTQGRDEETKGAQIGQGLYALYGITGYVGDLVSYTRLMA
LGIAGGSIAAALNLIIGMFPGIAVIIVGPLFFIAAHTFNMLLSLLGAYVHTARLQYVEYFSKFYEGGGKAFTPFRTINKF
ITIKRNK

Specific function: Involved in ATP-driven sodium extrusion [H]

COG id: COG1269

COG function: function code C; Archaeal/vacuolar-type H+-ATPase subunit I

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the V-ATPase 116 kDa subunit family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002490 [H]

Pfam domain/function: PF01496 V_ATPase_I [H]

EC number: 3.6.3.14

Molecular weight: Translated: 72926; Mature: 72795

Theoretical pI: Translated: 4.49; Mature: 4.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIVKMNKFTLLAFESEKEKLLKKIQSSSEVEFINLQDEEKVEGNEVFESLSKDDLDAET
CCEEEECCEEEEEECCHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHCCCCCCHHH
TLIEENVSKTRSALDFLKEFVAEVGGLKALKAGKESLTLDELEVKVENSNWEVVYSEVKK
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCHHHEEEEEECCCHHHHHHHHHH
MERELATLENEKTKLLGEIEILEPWQSFDAPLGELNNFEKVVAFLGVISSQNLENMKNEI
HHHHHHHHHCCHHHHHHHEHEECCHHHCCCCHHHHCCHHHHHHHHHHHCCCCHHHHHHHH
ESEFKESYIEVISNTDQDSYVFVMTMKERAEEMDEVLKNFGFSAFQTKYKEKASVLVEEF
HHHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
KLKIQEIEAQKSDLKGVLSNYREEKRTLELAYEYYSNILLRKEASENFLKTDRVVVIQGW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECC
VPKNDNSSLEGIIQSSVGDMYYLEFEEVKEEEVAEVPVKLHNKGPAAAFDSITEMYSLPR
CCCCCCCHHHHHHHHCCCCEEEEEHHHHCHHHHHHCCHHCCCCCCCHHHHHHHHHHCCCC
YDEIDPTPLLTPFYLVFFGMMVADLGYGLVLFVGSLLAMKLLNLDEAQEKFAKFFMYLSI
CCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
ATTIAGAIFGTAFGFELKFGLINPSKDTNLLLILSVGFGVIQIFFGLFIKAYMLIRDKQY
HHHHHHHHHHHHHCCEEEEEECCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCHHH
LYALFDVGSWIMLLIGLPMIFFDGPISLVGKVLAIVGSILIILTQGRDEETKGAQIGQGL
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHEEEECCCCCCCCCHHHHHHH
YALYGITGYVGDLVSYTRLMALGIAGGSIAAALNLIIGMFPGIAVIIVGPLFFIAAHTFN
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MLLSLLGAYVHTARLQYVEYFSKFYEGGGKAFTPFRTINKFITIKRNK
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHEEEECCC
>Mature Secondary Structure 
AIVKMNKFTLLAFESEKEKLLKKIQSSSEVEFINLQDEEKVEGNEVFESLSKDDLDAET
CEEEECCEEEEEECCHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHCCCCCCHHH
TLIEENVSKTRSALDFLKEFVAEVGGLKALKAGKESLTLDELEVKVENSNWEVVYSEVKK
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCHHHEEEEEECCCHHHHHHHHHH
MERELATLENEKTKLLGEIEILEPWQSFDAPLGELNNFEKVVAFLGVISSQNLENMKNEI
HHHHHHHHHCCHHHHHHHEHEECCHHHCCCCHHHHCCHHHHHHHHHHHCCCCHHHHHHHH
ESEFKESYIEVISNTDQDSYVFVMTMKERAEEMDEVLKNFGFSAFQTKYKEKASVLVEEF
HHHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
KLKIQEIEAQKSDLKGVLSNYREEKRTLELAYEYYSNILLRKEASENFLKTDRVVVIQGW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECC
VPKNDNSSLEGIIQSSVGDMYYLEFEEVKEEEVAEVPVKLHNKGPAAAFDSITEMYSLPR
CCCCCCCHHHHHHHHCCCCEEEEEHHHHCHHHHHHCCHHCCCCCCCHHHHHHHHHHCCCC
YDEIDPTPLLTPFYLVFFGMMVADLGYGLVLFVGSLLAMKLLNLDEAQEKFAKFFMYLSI
CCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
ATTIAGAIFGTAFGFELKFGLINPSKDTNLLLILSVGFGVIQIFFGLFIKAYMLIRDKQY
HHHHHHHHHHHHHCCEEEEEECCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCHHH
LYALFDVGSWIMLLIGLPMIFFDGPISLVGKVLAIVGSILIILTQGRDEETKGAQIGQGL
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHEEEECCCCCCCCCHHHHHHH
YALYGITGYVGDLVSYTRLMALGIAGGSIAAALNLIIGMFPGIAVIIVGPLFFIAAHTFN
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MLLSLLGAYVHTARLQYVEYFSKFYEGGGKAFTPFRTINKFITIKRNK
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8157629; 8144530 [H]