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The map label for this gene is scrA [H]

Identifier: 18310516

GI number: 18310516

Start: 1796505

End: 1797857

Strand: Reverse

Name: scrA [H]

Synonym: CPE1534

Alternate gene names: 18310516

Gene position: 1797857-1796505 (Counterclockwise)

Preceding gene: 18310517

Following gene: 18310515

Centisome position: 59.31

GC content: 31.71

Gene sequence:

>1353_bases
ATGAGTAAAGAACAAATAGTTGCTCAAGAAATATTAAAAAATATTGGTGGAAAAGAAAATATAAAATCAATGGAACACTG
TGCAACTAGATTAAGACTTATAGTTAAAGATAAAAGTCTAATAAATGAAAAGGCAATTGAGAATATTGATGGGGTAAGAG
GACAATTTTTTGCTGCTGCTCAATATCAAATAATTTTAGGAACTGGGTTTGTAAATAAAGTCTTTGCAGCTATGAATGGT
GAAGGAGTAGAAAATGGGAATATAAAAGAAGATGCATATAGTGATATGACTTTACCACAAAAAATATCTCGTACTTTAGG
AGATATTTTCGTTCCTATAATTCCAGTATTAGTTGCAACAGGTTTATTTATGGGATTAAGAGGACTTTTAACTAATTTAG
GAGTTGAATTTAGTCCAACTTTTAATACTTTATCAGAGGTTTTAACAGATACAGCATTTATATTCTTACCAGCCTTAGTA
GCTTGGTCAACAATGAAAAAATTTGGTGGAACACCTGTGGTTGGTATAGTATTAGGGCTTATGCTTGTAGCCCCTCAGCT
TCCAAATGCTTGGCAGGTAGCAGGAGGAGCAGATCCAATATATATTTCTTTATTAGGAATAAGTATCCCTATAGTAGGGT
ATCAAGGATCAGTACTTCCAGCTTTAGTATTAGGTATTATAGCAGCTAAATTAGAAAAATTTATTAGAAAGTTTATGCCA
GATGTACTAGATTTAATATTTACTCCATTTTTAACTTTATTAGTATCAATGATTCTTGGACTTTTAGTAGTAGGTCCTAT
AATGCATACAAGTGAAGTCTACATATTAGATTTATTTAAAATGTTTTTAAGCTTACCATTTGGAATAGGTGGAGCAATAA
TTGGAGGAGTTCACCAAGTTATAGTTGTAACTGGAGTTCATCATATATTTAATGCTTTAGAAGTTGAATTAATTTCAAGT
ACAGGATTAAATCCATTTAATGCAGTAATAACTGGGGCTATAGTAGCTCAAGGAGCAGCAGCTCTTGCAGTTGGATTTAA
GACAAAAGATAAGAAAAAACGTTCCTTATATATTTCTTCAGCAATACCAGCCTTTTTAGGAATTACAGAAGCGGCCATAT
TTGGAGTAAACTTAAGATTTATTAAACCATTTATATTTGCATGTATAGGTGGAGCTGCATCAGGAATGTTTGCATCAATG
ATGAAATTGGCTGGAACTGGTATGGGAATAACAGCTATACCGGGAACACTGCTTTATATTAATACAGGATTAATTCAGTA
CTTCATAACAATTGCTATTGGATTTGCTATTTCATTTGCATTAACATATATATTCTTTAAACCACAAGAATAA

Upstream 100 bases:

>100_bases
AATATAAAGTTTAAAGCTTGACAGAAACTATATGGAACTGATACCATATATTCAAGAAGTAAAGGATATCAAAAGAGGAT
AGGTTTTAGGAGGTTTTAAA

Downstream 100 bases:

>100_bases
TTTTTAGGCTCTGTGATTTTACAGAGCCTGCTTTTAAATATTTCAAAATAGTCTTATATGGTTAAAAACTTCTAGATAAT
GATATAATTTATAATATAAG

Product: PTS system, sucrose-specific IIBC component

Products: NA

Alternate protein names: EIIBC-Scr; EII-Scr; Sucrose-specific phosphotransferase enzyme IIB component; PTS system sucrose-specific EIIB component; Sucrose permease IIC component; PTS system sucrose-specific EIIC component [H]

Number of amino acids: Translated: 450; Mature: 449

Protein sequence:

>450_residues
MSKEQIVAQEILKNIGGKENIKSMEHCATRLRLIVKDKSLINEKAIENIDGVRGQFFAAAQYQIILGTGFVNKVFAAMNG
EGVENGNIKEDAYSDMTLPQKISRTLGDIFVPIIPVLVATGLFMGLRGLLTNLGVEFSPTFNTLSEVLTDTAFIFLPALV
AWSTMKKFGGTPVVGIVLGLMLVAPQLPNAWQVAGGADPIYISLLGISIPIVGYQGSVLPALVLGIIAAKLEKFIRKFMP
DVLDLIFTPFLTLLVSMILGLLVVGPIMHTSEVYILDLFKMFLSLPFGIGGAIIGGVHQVIVVTGVHHIFNALEVELISS
TGLNPFNAVITGAIVAQGAAALAVGFKTKDKKKRSLYISSAIPAFLGITEAAIFGVNLRFIKPFIFACIGGAASGMFASM
MKLAGTGMGITAIPGTLLYINTGLIQYFITIAIGFAISFALTYIFFKPQE

Sequences:

>Translated_450_residues
MSKEQIVAQEILKNIGGKENIKSMEHCATRLRLIVKDKSLINEKAIENIDGVRGQFFAAAQYQIILGTGFVNKVFAAMNG
EGVENGNIKEDAYSDMTLPQKISRTLGDIFVPIIPVLVATGLFMGLRGLLTNLGVEFSPTFNTLSEVLTDTAFIFLPALV
AWSTMKKFGGTPVVGIVLGLMLVAPQLPNAWQVAGGADPIYISLLGISIPIVGYQGSVLPALVLGIIAAKLEKFIRKFMP
DVLDLIFTPFLTLLVSMILGLLVVGPIMHTSEVYILDLFKMFLSLPFGIGGAIIGGVHQVIVVTGVHHIFNALEVELISS
TGLNPFNAVITGAIVAQGAAALAVGFKTKDKKKRSLYISSAIPAFLGITEAAIFGVNLRFIKPFIFACIGGAASGMFASM
MKLAGTGMGITAIPGTLLYINTGLIQYFITIAIGFAISFALTYIFFKPQE
>Mature_449_residues
SKEQIVAQEILKNIGGKENIKSMEHCATRLRLIVKDKSLINEKAIENIDGVRGQFFAAAQYQIILGTGFVNKVFAAMNGE
GVENGNIKEDAYSDMTLPQKISRTLGDIFVPIIPVLVATGLFMGLRGLLTNLGVEFSPTFNTLSEVLTDTAFIFLPALVA
WSTMKKFGGTPVVGIVLGLMLVAPQLPNAWQVAGGADPIYISLLGISIPIVGYQGSVLPALVLGIIAAKLEKFIRKFMPD
VLDLIFTPFLTLLVSMILGLLVVGPIMHTSEVYILDLFKMFLSLPFGIGGAIIGGVHQVIVVTGVHHIFNALEVELISST
GLNPFNAVITGAIVAQGAAALAVGFKTKDKKKRSLYISSAIPAFLGITEAAIFGVNLRFIKPFIFACIGGAASGMFASMM
KLAGTGMGITAIPGTLLYINTGLIQYFITIAIGFAISFALTYIFFKPQE

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1263

COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI2367362, Length=432, Percent_Identity=30.3240740740741, Blast_Score=223, Evalue=2e-59,
Organism=Escherichia coli, GI1790159, Length=391, Percent_Identity=31.2020460358056, Blast_Score=176, Evalue=2e-45,
Organism=Escherichia coli, GI1788769, Length=431, Percent_Identity=30.1624129930394, Blast_Score=155, Evalue=7e-39,
Organism=Escherichia coli, GI48994906, Length=462, Percent_Identity=27.4891774891775, Blast_Score=143, Evalue=3e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018113
- InterPro:   IPR004719
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013
- InterPro:   IPR011535
- InterPro:   IPR010973 [H]

Pfam domain/function: PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 48099; Mature: 47968

Theoretical pI: Translated: 9.19; Mature: 9.19

Prosite motif: PS01035 PTS_EIIB_TYPE_1_CYS ; PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKEQIVAQEILKNIGGKENIKSMEHCATRLRLIVKDKSLINEKAIENIDGVRGQFFAAA
CCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEE
QYQIILGTGFVNKVFAAMNGEGVENGNIKEDAYSDMTLPQKISRTLGDIFVPIIPVLVAT
EEEEEEECCHHHHHHHHHCCCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
GLFMGLRGLLTNLGVEFSPTFNTLSEVLTDTAFIFLPALVAWSTMKKFGGTPVVGIVLGL
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
MLVAPQLPNAWQVAGGADPIYISLLGISIPIVGYQGSVLPALVLGIIAAKLEKFIRKFMP
HHHCCCCCCCEECCCCCCCEEEEEEEHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHH
DVLDLIFTPFLTLLVSMILGLLVVGPIMHTSEVYILDLFKMFLSLPFGIGGAIIGGVHQV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
IVVTGVHHIFNALEVELISSTGLNPFNAVITGAIVAQGAAALAVGFKTKDKKKRSLYISS
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHEECCCCCCCHHHHEEHHH
AIPAFLGITEAAIFGVNLRFIKPFIFACIGGAASGMFASMMKLAGTGMGITAIPGTLLYI
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEE
NTGLIQYFITIAIGFAISFALTYIFFKPQE
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SKEQIVAQEILKNIGGKENIKSMEHCATRLRLIVKDKSLINEKAIENIDGVRGQFFAAA
CHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEE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HHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8628219 [H]