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The map label for this gene is crp [C]

Identifier: 18310423

GI number: 18310423

Start: 1699211

End: 1699903

Strand: Reverse

Name: crp [C]

Synonym: CPE1441

Alternate gene names: 18310423

Gene position: 1699903-1699211 (Counterclockwise)

Preceding gene: 18310424

Following gene: 18310422

Centisome position: 56.08

GC content: 27.13

Gene sequence:

>693_bases
ATGAAAGCATTAAGTAGTGATAAATTAAAAGATATAAGTTTCTTTTCGGGACTTAATGATGAAACCTTAAAATATATAGA
GAAAAATTCTAAAGTTTTAAAAAAGAAAAAGGGAGAGCATATTTTTAGAGATAAAGATAAGGTTCAGGATATTTTTATTG
TTTTAAAAGGAAAAGTAACCCTATATAAGATGAATGAATATGGGCAAAAGAGAATAGTTTACATACTTGGAGAGGAAAGC
TTTTTAAATGAAGTAATAGTTGATGACCTTCCTGCCTCAATAAATGGAGAAGCTTTTGAAAACTCAATAATACTGAGTAT
AGATAAAAATAAATTATTAAATATAATGAGCCAAGATTTTGAGCTTACAAAGATTGTTTTAAATGAAATGAGCAAAAAGG
TAAGAAGATTATATAGACAAATGAAAAATGTAACTCCAATAAAATTAGAAAAAAGAGTAGCAGCAAAGCTTTGGAAGTTA
AGCAAGGATTATGGAAAAGAAGTGCCAGAGGGGACACTTATTGACTTAGATATAAGTATAACTTACTTAGCAGATATGTT
TGGTTCTCCAAGGGAAAGTGTATCTAGAGCTATTAAAACCTTAAGAGATGAAAATCTAATAATAAAAGAAAACAAAAAGA
TAATAGTACCTGATAGAGAAAAAATTGCTGCATATTTTAAATCATTAATATAA

Upstream 100 bases:

>100_bases
AAAAATATAATTATATAAGTTCTATTATTTAATGAAATTTTGTGTTAAATTAGATTATATTGTGTTTGAATAATAAGATT
TTTATAGAGTAGGAGAGATT

Downstream 100 bases:

>100_bases
ATAAGCTTTAGAAATTAAAAGCTATAAGGGGTTATTTATTTTTTTGTTTTGTAATTTAAGAATTTTTACAGTGTAACAAA
AATCACATACTCAATAAAAC

Product: Crp/Fnr family transcriptional regulator

Products: NA

Alternate protein names: Crp/FNR Family Transcriptional Regulator; Transcriptional Regulator; CRP/FNR Family Transcriptional Regulator; Crp Family Transcriptional Regulator; Crp/Fnr Family Transcriptional Regulator; Transcription Regulator; Cyclic AMP Receptor Protein; CRP Family Transcriptional Regulator; Crp-Family Transcriptional Regulator; Catabolite Gene Activator; FNR-Like Catabolite Gene Activator Protein

Number of amino acids: Translated: 230; Mature: 230

Protein sequence:

>230_residues
MKALSSDKLKDISFFSGLNDETLKYIEKNSKVLKKKKGEHIFRDKDKVQDIFIVLKGKVTLYKMNEYGQKRIVYILGEES
FLNEVIVDDLPASINGEAFENSIILSIDKNKLLNIMSQDFELTKIVLNEMSKKVRRLYRQMKNVTPIKLEKRVAAKLWKL
SKDYGKEVPEGTLIDLDISITYLADMFGSPRESVSRAIKTLRDENLIIKENKKIIVPDREKIAAYFKSLI

Sequences:

>Translated_230_residues
MKALSSDKLKDISFFSGLNDETLKYIEKNSKVLKKKKGEHIFRDKDKVQDIFIVLKGKVTLYKMNEYGQKRIVYILGEES
FLNEVIVDDLPASINGEAFENSIILSIDKNKLLNIMSQDFELTKIVLNEMSKKVRRLYRQMKNVTPIKLEKRVAAKLWKL
SKDYGKEVPEGTLIDLDISITYLADMFGSPRESVSRAIKTLRDENLIIKENKKIIVPDREKIAAYFKSLI
>Mature_230_residues
MKALSSDKLKDISFFSGLNDETLKYIEKNSKVLKKKKGEHIFRDKDKVQDIFIVLKGKVTLYKMNEYGQKRIVYILGEES
FLNEVIVDDLPASINGEAFENSIILSIDKNKLLNIMSQDFELTKIVLNEMSKKVRRLYRQMKNVTPIKLEKRVAAKLWKL
SKDYGKEVPEGTLIDLDISITYLADMFGSPRESVSRAIKTLRDENLIIKENKKIIVPDREKIAAYFKSLI

Specific function: This Protein Complexes With Cyclic AMP And Binds To Specific DNA Sites Near The Promoter To Regulate The Transcription Of Several Catabolite-Sensitive Operons. The Protein Induces A Severe Bend In The DNA. Acts As A Negative Regulator Of Its Own Synthesi

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 26599; Mature: 26599

Theoretical pI: Translated: 10.06; Mature: 10.06

Prosite motif: PS50042 CNMP_BINDING_3 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKALSSDKLKDISFFSGLNDETLKYIEKNSKVLKKKKGEHIFRDKDKVQDIFIVLKGKVT
CCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHCCHHHHHEEEEEEECCEE
LYKMNEYGQKRIVYILGEESFLNEVIVDDLPASINGEAFENSIILSIDKNKLLNIMSQDF
EEEECCCCCEEEEEEECCHHHHHHHHHHCCCCCCCCCCCCCCEEEEECHHHHHHHHHCCH
ELTKIVLNEMSKKVRRLYRQMKNVTPIKLEKRVAAKLWKLSKDYGKEVPEGTLIDLDISI
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEHH
TYLADMFGSPRESVSRAIKTLRDENLIIKENKKIIVPDREKIAAYFKSLI
HHHHHHHCCCHHHHHHHHHHHCCCCEEEECCCEEECCCHHHHHHHHHHHC
>Mature Secondary Structure
MKALSSDKLKDISFFSGLNDETLKYIEKNSKVLKKKKGEHIFRDKDKVQDIFIVLKGKVT
CCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHCCHHHHHEEEEEEECCEE
LYKMNEYGQKRIVYILGEESFLNEVIVDDLPASINGEAFENSIILSIDKNKLLNIMSQDF
EEEECCCCCEEEEEEECCHHHHHHHHHHCCCCCCCCCCCCCCEEEEECHHHHHHHHHCCH
ELTKIVLNEMSKKVRRLYRQMKNVTPIKLEKRVAAKLWKLSKDYGKEVPEGTLIDLDISI
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEHH
TYLADMFGSPRESVSRAIKTLRDENLIIKENKKIIVPDREKIAAYFKSLI
HHHHHHHCCCHHHHHHHHHHHCCCCEEEECCCEEECCCHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA