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The map label for this gene is nirC [H]

Identifier: 18310424

GI number: 18310424

Start: 1700121

End: 1700918

Strand: Reverse

Name: nirC [H]

Synonym: CPE1442

Alternate gene names: 18310424

Gene position: 1700918-1700121 (Counterclockwise)

Preceding gene: 18310425

Following gene: 18310423

Centisome position: 56.11

GC content: 31.2

Gene sequence:

>798_bases
ATGTTTAGGGAAGAATTTAGTAATGTTATTAGTGCAGGTAGAGGTAAGATTGACTTGCTAAATAATAGTAAGGGCCGTTA
TTTAGTATATGCTATGCTTGCTGGACTTTATATAAGTTTTGGTATAATGCTAGCATTTACCATAGGAGGAATATTAGATA
GTGCTAATTCTCCAAGCACTAAAATAATAATGGGAGCATCTTTTGGTGTAGCCTTAAGTTTAGTGGTTTTTGCAGGATCA
GAACTTTTTACAGGAAATAATTTTGTAATGACTATAGGAATTCTAAACAAAGAGGTAACATTTAAAGAATGCGGAAAAGT
ATGGGGACTAGCTTACGCTGGTAATTTTTTAGGATCTATAATAGCCGCTTTAGGTTTTATAGGGGCAGGATTAACTACAG
GTAGTGTAAGTGATTTTATGATTAAAACTGCGGAAATAAAAATAAGCTTGCCACCAGAGCAATTATTTATAAGAGGAATA
TTCTGTAATATATTAGTATGCTTAGCTGTATGGTGTACCTTTAGATTAAAAACAGAAACATCAAAGTTAATAATGATATT
CTGGTGTCTTTTTGCCTTTGTAACATCTGGTTTTGAACACAGCATTGCAAATATGAGCTTATTAGTAATAGGAGTTATAT
TAACAAAGGGAGCTACTATAACAGTAGCAGGAAGTTTATATAATCTATTTTTTGTTACATTAGGAAATATACTAGGTGGT
GTTCTTTTAGGGGTAACCTACCATTATATAGCTAATAAAAAAGTAGAAAATAAAAAACTAGTTCATATTCAAAAATAG

Upstream 100 bases:

>100_bases
ATAAAAAGTTAAAAATAAATTTTTTCTTCTTTTATTATAGTGATTAAGGCTTTTTTATTTTAGAATTTAAGGGAAGACTT
TTAAGTGGGGAGGCTTTAAC

Downstream 100 bases:

>100_bases
CTTTTTATAAAACTTACAAAGATTATGAAGAGGATTCTATTAATTCTCAGAATAAGTTTGTAAGTTTTTTTATTATATTT
TCATAAAATCCTATTTTATA

Product: nitrite transporter

Products: Proton [Cytoplasm]; nitrite [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 265; Mature: 265

Protein sequence:

>265_residues
MFREEFSNVISAGRGKIDLLNNSKGRYLVYAMLAGLYISFGIMLAFTIGGILDSANSPSTKIIMGASFGVALSLVVFAGS
ELFTGNNFVMTIGILNKEVTFKECGKVWGLAYAGNFLGSIIAALGFIGAGLTTGSVSDFMIKTAEIKISLPPEQLFIRGI
FCNILVCLAVWCTFRLKTETSKLIMIFWCLFAFVTSGFEHSIANMSLLVIGVILTKGATITVAGSLYNLFFVTLGNILGG
VLLGVTYHYIANKKVENKKLVHIQK

Sequences:

>Translated_265_residues
MFREEFSNVISAGRGKIDLLNNSKGRYLVYAMLAGLYISFGIMLAFTIGGILDSANSPSTKIIMGASFGVALSLVVFAGS
ELFTGNNFVMTIGILNKEVTFKECGKVWGLAYAGNFLGSIIAALGFIGAGLTTGSVSDFMIKTAEIKISLPPEQLFIRGI
FCNILVCLAVWCTFRLKTETSKLIMIFWCLFAFVTSGFEHSIANMSLLVIGVILTKGATITVAGSLYNLFFVTLGNILGG
VLLGVTYHYIANKKVENKKLVHIQK
>Mature_265_residues
MFREEFSNVISAGRGKIDLLNNSKGRYLVYAMLAGLYISFGIMLAFTIGGILDSANSPSTKIIMGASFGVALSLVVFAGS
ELFTGNNFVMTIGILNKEVTFKECGKVWGLAYAGNFLGSIIAALGFIGAGLTTGSVSDFMIKTAEIKISLPPEQLFIRGI
FCNILVCLAVWCTFRLKTETSKLIMIFWCLFAFVTSGFEHSIANMSLLVIGVILTKGATITVAGSLYNLFFVTLGNILGG
VLLGVTYHYIANKKVENKKLVHIQK

Specific function: May act as a nitrite transporter [H]

COG id: COG2116

COG function: function code P; Formate/nitrite family of transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FNT transporter (TC 2.A.44) family [H]

Homologues:

Organism=Escherichia coli, GI87082249, Length=266, Percent_Identity=38.7218045112782, Blast_Score=160, Evalue=6e-41,
Organism=Escherichia coli, GI1787132, Length=251, Percent_Identity=29.0836653386454, Blast_Score=81, Evalue=7e-17,
Organism=Saccharomyces cerevisiae, GI6321779, Length=186, Percent_Identity=30.6451612903226, Blast_Score=77, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000292 [H]

Pfam domain/function: PF01226 Form_Nir_trans [H]

EC number: NA

Molecular weight: Translated: 28621; Mature: 28621

Theoretical pI: Translated: 9.57; Mature: 9.57

Prosite motif: PS01006 FORMATE_NITRITE_TP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFREEFSNVISAGRGKIDLLNNSKGRYLVYAMLAGLYISFGIMLAFTIGGILDSANSPST
CCHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
KIIMGASFGVALSLVVFAGSELFTGNNFVMTIGILNKEVTFKECGKVWGLAYAGNFLGSI
EEEEECCHHHHHHHHHHCCCEEEECCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHH
IAALGFIGAGLTTGSVSDFMIKTAEIKISLPPEQLFIRGIFCNILVCLAVWCTFRLKTET
HHHHHHHHCCCCCCCCHHHEEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHEEEECCC
SKLIMIFWCLFAFVTSGFEHSIANMSLLVIGVILTKGATITVAGSLYNLFFVTLGNILGG
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHH
VLLGVTYHYIANKKVENKKLVHIQK
HHHHHHHHHHHCCCCCCCEEEEEEC
>Mature Secondary Structure
MFREEFSNVISAGRGKIDLLNNSKGRYLVYAMLAGLYISFGIMLAFTIGGILDSANSPST
CCHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
KIIMGASFGVALSLVVFAGSELFTGNNFVMTIGILNKEVTFKECGKVWGLAYAGNFLGSI
EEEEECCHHHHHHHHHHCCCEEEECCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHH
IAALGFIGAGLTTGSVSDFMIKTAEIKISLPPEQLFIRGIFCNILVCLAVWCTFRLKTET
HHHHHHHHCCCCCCCCHHHEEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHEEEECCC
SKLIMIFWCLFAFVTSGFEHSIANMSLLVIGVILTKGATITVAGSLYNLFFVTLGNILGG
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHH
VLLGVTYHYIANKKVENKKLVHIQK
HHHHHHHHHHHCCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; nitrite [Periplasm] [C]

Specific reaction: Proton [Periplasm] + nitrite [Periplasm] = Proton [Cytoplasm] + nitrite [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1987123; 11677609 [H]