Click here to switch to the map view.

The map label for this gene is deoD [H]

Identifier: 18310380

GI number: 18310380

Start: 1649585

End: 1650292

Strand: Direct

Name: deoD [H]

Synonym: CPE1398

Alternate gene names: 18310380

Gene position: 1649585-1650292 (Clockwise)

Preceding gene: 18310378

Following gene: 18310386

Centisome position: 54.42

GC content: 33.47

Gene sequence:

>708_bases
ATGAGTATTCATATAGGTGCAAAAGAAGGTCAAATAGCCGAAACAATTTTATTACCAGGAGATCCTTTAAGAGCTAAATT
TATAGCTGAAACTTTTTTAGAAAATCCAGTTTGTTACAATGAAGTTAGAGGAATGTTAGGATATACAGGAACATATAAAG
GAAAAAGAATATCAGTTCAAGGTACTGGTATGGGGGTTCCTTCAATTTCTATTTACGTTAATGAACTTATAAGAGATTAT
GGAGTTAAAAATTTAATAAGAGTAGGTACTGCTGGCGGTATGCAAGAAGATATAAAAGTTAGAGATTTAGTTTTAGCAAT
GTCATCTCATACTGATTCTGCAATAAATAAAGTTAGATTTAACGGTTTAGATTTTGCTCCAACAGCATCATTTAAACTTT
TAAAGGCTGCTTACGATACTGCCGTTGAAAAAGGATATTCTCCTAAGGTTGGTAGCGTATTCACAGCTGATAGCTTCTAT
AATGATAATCCTGAAGCATGGAAACAATGGGCTAAATTTGGTACTTTAGCTGTTGAAATGGAAACTGCAGCTTTATATAC
CTTAGCAGCTAAGTATGGTGTTAATGCCTTAACAATACTTACTATAAGTGATCATTTAATTACTGCTGAGGAAACTACTA
GTGAGGAGCGTCAAACTACCTTCACAAAGATGATGGAAGTTGCTCTTGATGCTGCTATAACTTTATAA

Upstream 100 bases:

>100_bases
CTACTTAAATTAAAATTTTAATTTTTATAATTTTTAGCATTTTTTCATTATTTATGATAAAATTTATTTATAAAACATTT
ACATTATGAGGAGGTACATT

Downstream 100 bases:

>100_bases
AATAAAAGAGCTTTATCAAAATAACTTTTGATAAAGCTCCTTTTTATTTATTAATTACTCTTCTCTTCTTCTAATCCTGG
TAATGAAAAGTCTTGTACAT

Product: purine nucleoside phosphorylase

Products: NA

Alternate protein names: PNP [H]

Number of amino acids: Translated: 235; Mature: 234

Protein sequence:

>235_residues
MSIHIGAKEGQIAETILLPGDPLRAKFIAETFLENPVCYNEVRGMLGYTGTYKGKRISVQGTGMGVPSISIYVNELIRDY
GVKNLIRVGTAGGMQEDIKVRDLVLAMSSHTDSAINKVRFNGLDFAPTASFKLLKAAYDTAVEKGYSPKVGSVFTADSFY
NDNPEAWKQWAKFGTLAVEMETAALYTLAAKYGVNALTILTISDHLITAEETTSEERQTTFTKMMEVALDAAITL

Sequences:

>Translated_235_residues
MSIHIGAKEGQIAETILLPGDPLRAKFIAETFLENPVCYNEVRGMLGYTGTYKGKRISVQGTGMGVPSISIYVNELIRDY
GVKNLIRVGTAGGMQEDIKVRDLVLAMSSHTDSAINKVRFNGLDFAPTASFKLLKAAYDTAVEKGYSPKVGSVFTADSFY
NDNPEAWKQWAKFGTLAVEMETAALYTLAAKYGVNALTILTISDHLITAEETTSEERQTTFTKMMEVALDAAITL
>Mature_234_residues
SIHIGAKEGQIAETILLPGDPLRAKFIAETFLENPVCYNEVRGMLGYTGTYKGKRISVQGTGMGVPSISIYVNELIRDYG
VKNLIRVGTAGGMQEDIKVRDLVLAMSSHTDSAINKVRFNGLDFAPTASFKLLKAAYDTAVEKGYSPKVGSVFTADSFYN
DNPEAWKQWAKFGTLAVEMETAALYTLAAKYGVNALTILTISDHLITAEETTSEERQTTFTKMMEVALDAAITL

Specific function: Cleavage Of Guanosine Or Inosine To Respective Bases And Sugar-1-Phosphate Molecules. [C]

COG id: COG0813

COG function: function code F; Purine-nucleoside phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family [H]

Homologues:

Organism=Escherichia coli, GI1790844, Length=230, Percent_Identity=51.7391304347826, Blast_Score=257, Evalue=4e-70,
Organism=Escherichia coli, GI1790265, Length=249, Percent_Identity=28.5140562248996, Blast_Score=88, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004402
- InterPro:   IPR018017
- InterPro:   IPR018016
- InterPro:   IPR000845 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: =2.4.2.1 [H]

Molecular weight: Translated: 25640; Mature: 25508

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: PS01232 PNP_UDP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIHIGAKEGQIAETILLPGDPLRAKFIAETFLENPVCYNEVRGMLGYTGTYKGKRISVQ
CEEECCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCEEEEE
GTGMGVPSISIYVNELIRDYGVKNLIRVGTAGGMQEDIKVRDLVLAMSSHTDSAINKVRF
ECCCCCCHHHHHHHHHHHHHCHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCHHHHHHEEE
NGLDFAPTASFKLLKAAYDTAVEKGYSPKVGSVFTADSFYNDNPEAWKQWAKFGTLAVEM
CCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCHHHHHHHHHHCCEEEEE
ETAALYTLAAKYGVNALTILTISDHLITAEETTSEERQTTFTKMMEVALDAAITL
HHHHHHHHHHHHCCCEEEEEEECCCEEECCCCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SIHIGAKEGQIAETILLPGDPLRAKFIAETFLENPVCYNEVRGMLGYTGTYKGKRISVQ
EEECCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCEEEEE
GTGMGVPSISIYVNELIRDYGVKNLIRVGTAGGMQEDIKVRDLVLAMSSHTDSAINKVRF
ECCCCCCHHHHHHHHHHHHHCHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCHHHHHHEEE
NGLDFAPTASFKLLKAAYDTAVEKGYSPKVGSVFTADSFYNDNPEAWKQWAKFGTLAVEM
CCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCHHHHHHHHHHCCEEEEE
ETAALYTLAAKYGVNALTILTISDHLITAEETTSEERQTTFTKMMEVALDAAITL
HHHHHHHHHHHHCCCEEEEEEECCCEEECCCCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA