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The map label for this gene is fabH [H]

Identifier: 18310050

GI number: 18310050

Start: 1274358

End: 1275332

Strand: Direct

Name: fabH [H]

Synonym: CPE1068

Alternate gene names: 18310050

Gene position: 1274358-1275332 (Clockwise)

Preceding gene: 18310049

Following gene: 18310051

Centisome position: 42.04

GC content: 32.1

Gene sequence:

>975_bases
ATGAAAAATGCTAAAATGATAGGCTTTGGCTTATATACACCTAAAAATTTAGTGGAAAATGAAAGATTACAAGAATTTTT
AGAGACTAGCGATGAGTGGATTAGAACTAGAACCGGAATAGAAAGAAGATATATTTCATTAGATGAAAATACTTCAGATT
TGGCAGTAGAAGCTAGTAAAAAAGCCTTAAGTCAAGCAAGATTAAGTGCTGAAGAAATAGATTTAATAATAGTAGCTACT
GTAACTCCAGATAATTTTACTCCATCTACAGCTTGTATTGTTCAAGATAAGTTAGGAGCTAAAAATGCATGGGCCTTTGA
TATAAATGCAGCTTGTACTGGATTTATATATGCACTTAAATTAGGAAGATCTTTAATAAGATCAGGTGAAGCTAATAATG
CCTTAATAATAGGTGCAGAAACTTTATCAAAAGCACTTAACTGGGAAGATAGAGGAAGTTGTGTTCTTTTTGGAGATGGT
GCAGGTGCTACTGTTCTTACAAGCACAGAAGAAGATTGTGGAATAAAATGTGTAAATGTAAAATCTGATGGTTCTAAGGG
AGATTCCCTTGTTATTCAGGGGTTACCTCTAAATAGTCCATTTAAAGATGGAAGAGAAGTTTCTGAAAATTACATAAACA
TGAATGGAAGAGAGATATTTAAGTTTGCAACAAAAGTAATGGAAGAAAGTATAGTAGAGATTTTAGAAAAAGAAAACATA
AAAATAGAAGATATAGCTGCTATAATTCCTCATCAAGCAAATTTAAGAATTATAGATTACGTAGTTAAAAGATTAGGAAT
ACCAAGAGAAAAGTTTATAACAAATTTACAGAATTATGGAAACACATCAGGGGCAAGCATTCCAATAGCCCTTTGTGAAT
CAATTGATGAAGGAAATTTGAAAAAAGGAGACAACATAATAATGGTTGGCTTTGGTGGAGGCCTTACTTGGGGAGCCGCT
TTAATTAAGTTATAA

Upstream 100 bases:

>100_bases
CTAGGTGTTGGTGAAGAGGAGGTTTTAATAAGTTCTCTAGATAAGTTAGATAAGTTCTTTCAAAAGAAATTAGAACTTAT
GAAATCAAAGGAGAGTTAAT

Downstream 100 bases:

>100_bases
TTCTTGAAAAAACAAAAATCTAGAAAATAATACTAAATGAGAATATAATTATAGATATATTTATTTTTAATCCGTTAAAT
TTTGGGAGGTATTTTAATGG

Product: 3-oxoacyl-(acyl carrier protein) synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MKNAKMIGFGLYTPKNLVENERLQEFLETSDEWIRTRTGIERRYISLDENTSDLAVEASKKALSQARLSAEEIDLIIVAT
VTPDNFTPSTACIVQDKLGAKNAWAFDINAACTGFIYALKLGRSLIRSGEANNALIIGAETLSKALNWEDRGSCVLFGDG
AGATVLTSTEEDCGIKCVNVKSDGSKGDSLVIQGLPLNSPFKDGREVSENYINMNGREIFKFATKVMEESIVEILEKENI
KIEDIAAIIPHQANLRIIDYVVKRLGIPREKFITNLQNYGNTSGASIPIALCESIDEGNLKKGDNIIMVGFGGGLTWGAA
LIKL

Sequences:

>Translated_324_residues
MKNAKMIGFGLYTPKNLVENERLQEFLETSDEWIRTRTGIERRYISLDENTSDLAVEASKKALSQARLSAEEIDLIIVAT
VTPDNFTPSTACIVQDKLGAKNAWAFDINAACTGFIYALKLGRSLIRSGEANNALIIGAETLSKALNWEDRGSCVLFGDG
AGATVLTSTEEDCGIKCVNVKSDGSKGDSLVIQGLPLNSPFKDGREVSENYINMNGREIFKFATKVMEESIVEILEKENI
KIEDIAAIIPHQANLRIIDYVVKRLGIPREKFITNLQNYGNTSGASIPIALCESIDEGNLKKGDNIIMVGFGGGLTWGAA
LIKL
>Mature_324_residues
MKNAKMIGFGLYTPKNLVENERLQEFLETSDEWIRTRTGIERRYISLDENTSDLAVEASKKALSQARLSAEEIDLIIVAT
VTPDNFTPSTACIVQDKLGAKNAWAFDINAACTGFIYALKLGRSLIRSGEANNALIIGAETLSKALNWEDRGSCVLFGDG
AGATVLTSTEEDCGIKCVNVKSDGSKGDSLVIQGLPLNSPFKDGREVSENYINMNGREIFKFATKVMEESIVEILEKENI
KIEDIAAIIPHQANLRIIDYVVKRLGIPREKFITNLQNYGNTSGASIPIALCESIDEGNLKKGDNIIMVGFGGGLTWGAA
LIKL

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=323, Percent_Identity=39.6284829721362, Blast_Score=247, Evalue=9e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.41 [H]

Molecular weight: Translated: 35343; Mature: 35343

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNAKMIGFGLYTPKNLVENERLQEFLETSDEWIRTRTGIERRYISLDENTSDLAVEASK
CCCCEEEEEECCCCHHHHHHHHHHHHHHCHHHHHHHHCCCCCEEEEECCCCCHHHHHHHH
KALSQARLSAEEIDLIIVATVTPDNFTPSTACIVQDKLGAKNAWAFDINAACTGFIYALK
HHHHHHHCCHHHEEEEEEEEECCCCCCCCEEEEEECCCCCCCCEEEECCHHHHHHHHHHH
LGRSLIRSGEANNALIIGAETLSKALNWEDRGSCVLFGDGAGATVLTSTEEDCGIKCVNV
HHHHHHHCCCCCCEEEEEHHHHHHHCCCCCCCCEEEEECCCCCEEEECCCCCCCEEEEEE
KSDGSKGDSLVIQGLPLNSPFKDGREVSENYINMNGREIFKFATKVMEESIVEILEKENI
CCCCCCCCEEEEEECCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
KIEDIAAIIPHQANLRIIDYVVKRLGIPREKFITNLQNYGNTSGASIPIALCESIDEGNL
CHHHHHHCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCEEHHHHHCCCCCCCC
KKGDNIIMVGFGGGLTWGAALIKL
CCCCCEEEEEECCCHHHHHHHHCC
>Mature Secondary Structure
MKNAKMIGFGLYTPKNLVENERLQEFLETSDEWIRTRTGIERRYISLDENTSDLAVEASK
CCCCEEEEEECCCCHHHHHHHHHHHHHHCHHHHHHHHCCCCCEEEEECCCCCHHHHHHHH
KALSQARLSAEEIDLIIVATVTPDNFTPSTACIVQDKLGAKNAWAFDINAACTGFIYALK
HHHHHHHCCHHHEEEEEEEEECCCCCCCCEEEEEECCCCCCCCEEEECCHHHHHHHHHHH
LGRSLIRSGEANNALIIGAETLSKALNWEDRGSCVLFGDGAGATVLTSTEEDCGIKCVNV
HHHHHHHCCCCCCEEEEEHHHHHHHCCCCCCCCEEEEECCCCCEEEECCCCCCCEEEEEE
KSDGSKGDSLVIQGLPLNSPFKDGREVSENYINMNGREIFKFATKVMEESIVEILEKENI
CCCCCCCCEEEEEECCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
KIEDIAAIIPHQANLRIIDYVVKRLGIPREKFITNLQNYGNTSGASIPIALCESIDEGNL
CHHHHHHCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCEEHHHHHCCCCCCCC
KKGDNIIMVGFGGGLTWGAALIKL
CCCCCEEEEEECCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA