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The map label for this gene is fabD [H]

Identifier: 18310051

GI number: 18310051

Start: 1275429

End: 1276373

Strand: Direct

Name: fabD [H]

Synonym: CPE1069

Alternate gene names: 18310051

Gene position: 1275429-1276373 (Clockwise)

Preceding gene: 18310050

Following gene: 18310052

Centisome position: 42.07

GC content: 30.37

Gene sequence:

>945_bases
ATGGCTAAACTAGGATTTTTATTTGCAGGGCAAGGAGCCCAATATGTAGGAATGGGCAAAGAATTCTTTGATAACTTTGA
AGAAAGTAAAGAGGTATTTAAAAGAAGTAGTGAAGCCTTAGGCATAGATATGGAAGAACTTTGTTTTAGTGATCCTGAGG
GATTATTAAATAAAACTGAATTTACTCAGCCTGCAATAATAACCACAAACATGGCTATACTTACAGCACTAGATAAATTA
GGAGTTAAATCTCATATAAGTTGTGGATTAAGCTTAGGAGAATATTCTGCACTTATTCATAGTGGTGCCATTAATTTTGA
AGATGGAGTTAAACTAGTTAAAAAAAGAGGTAAATTCATGCAAGAAGCTGTGGCAGAAGGTATTGGTGGAATGGTTGCAG
TTTTAAGAATGACTCCAGAACAAGTTGATGAAATAATAGAAAAAAGTTCTCCATATGGAATAGTTGAGGGTGCAAATTAT
AATTCACCTGGCCAAATTGTTATTTCTGGAGAATTAGTAGCTTTAGAAAAAGCTATGGAATTTATAAAAGAAGTTGGTGG
AAGAGCTATAAAATTACCTGTATCAGCTCCATTTCACTGTTCAATGTTACAACCAGCAGCTGAGAAATTAGAAGATGAAT
TAAATAAAATTTCAATAAATAAATTAAATGGAATTGTTATGTCTAATGTTAAGGGAGAAGCCTATTTAGAAGATGATAAT
ATAATAGAACTTTTAACTTCTCAAGTTAAAAAGCCTGTTTTATTTATAAATGATATAGAAAAAATGATTGAAAGTGGTGT
AGATACTTTTATTGAAATAGGTCCTGGTAAAGCTTTAAGTGGATTTGTTAAAAAAATAAATAAAAATGTTACAGTGCTTA
ATGTAGAGGATTTAAAATCTTTAGAAAAAACATTATCAAAATTAAGAGAGATGGAGGTACTTTAA

Upstream 100 bases:

>100_bases
ATAATTCTTGAAAAAACAAAAATCTAGAAAATAATACTAAATGAGAATATAATTATAGATATATTTATTTTTAATCCGTT
AAATTTTGGGAGGTATTTTA

Downstream 100 bases:

>100_bases
CCTATGTTAAAAGATAAAGTAGCAATAGTAACTGGTGGAACAAGAGGAATTGGAAGAGCAATCGCTTTAAAATTAGCAGA
TCAAGGAGCTAATATTGTTA

Product: malonyl CoA-acyl carrier protein transacylase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 314; Mature: 313

Protein sequence:

>314_residues
MAKLGFLFAGQGAQYVGMGKEFFDNFEESKEVFKRSSEALGIDMEELCFSDPEGLLNKTEFTQPAIITTNMAILTALDKL
GVKSHISCGLSLGEYSALIHSGAINFEDGVKLVKKRGKFMQEAVAEGIGGMVAVLRMTPEQVDEIIEKSSPYGIVEGANY
NSPGQIVISGELVALEKAMEFIKEVGGRAIKLPVSAPFHCSMLQPAAEKLEDELNKISINKLNGIVMSNVKGEAYLEDDN
IIELLTSQVKKPVLFINDIEKMIESGVDTFIEIGPGKALSGFVKKINKNVTVLNVEDLKSLEKTLSKLREMEVL

Sequences:

>Translated_314_residues
MAKLGFLFAGQGAQYVGMGKEFFDNFEESKEVFKRSSEALGIDMEELCFSDPEGLLNKTEFTQPAIITTNMAILTALDKL
GVKSHISCGLSLGEYSALIHSGAINFEDGVKLVKKRGKFMQEAVAEGIGGMVAVLRMTPEQVDEIIEKSSPYGIVEGANY
NSPGQIVISGELVALEKAMEFIKEVGGRAIKLPVSAPFHCSMLQPAAEKLEDELNKISINKLNGIVMSNVKGEAYLEDDN
IIELLTSQVKKPVLFINDIEKMIESGVDTFIEIGPGKALSGFVKKINKNVTVLNVEDLKSLEKTLSKLREMEVL
>Mature_313_residues
AKLGFLFAGQGAQYVGMGKEFFDNFEESKEVFKRSSEALGIDMEELCFSDPEGLLNKTEFTQPAIITTNMAILTALDKLG
VKSHISCGLSLGEYSALIHSGAINFEDGVKLVKKRGKFMQEAVAEGIGGMVAVLRMTPEQVDEIIEKSSPYGIVEGANYN
SPGQIVISGELVALEKAMEFIKEVGGRAIKLPVSAPFHCSMLQPAAEKLEDELNKISINKLNGIVMSNVKGEAYLEDDNI
IELLTSQVKKPVLFINDIEKMIESGVDTFIEIGPGKALSGFVKKINKNVTVLNVEDLKSLEKTLSKLREMEVL

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=323, Percent_Identity=31.5789473684211, Blast_Score=138, Evalue=6e-33,
Organism=Homo sapiens, GI27477045, Length=108, Percent_Identity=35.1851851851852, Blast_Score=72, Evalue=7e-13,
Organism=Escherichia coli, GI1787334, Length=307, Percent_Identity=38.1107491856677, Blast_Score=207, Evalue=7e-55,
Organism=Caenorhabditis elegans, GI71984332, Length=291, Percent_Identity=28.5223367697594, Blast_Score=112, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17550940, Length=295, Percent_Identity=29.4915254237288, Blast_Score=109, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI212642053, Length=301, Percent_Identity=26.578073089701, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24665753, Length=300, Percent_Identity=32, Blast_Score=140, Evalue=8e-34,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 34273; Mature: 34142

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKLGFLFAGQGAQYVGMGKEFFDNFEESKEVFKRSSEALGIDMEELCFSDPEGLLNKTE
CCCEEEEEECCCCCEECCCHHHHHHHHHHHHHHHHCCHHCCCCHHHHHCCCCHHHCCCCC
FTQPAIITTNMAILTALDKLGVKSHISCGLSLGEYSALIHSGAINFEDGVKLVKKRGKFM
CCCCEEEEHHHHHHHHHHHHCCHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
QEAVAEGIGGMVAVLRMTPEQVDEIIEKSSPYGIVEGANYNSPGQIVISGELVALEKAME
HHHHHHCHHHHHHHHHCCHHHHHHHHHCCCCCEEEECCCCCCCCEEEEECHHHHHHHHHH
FIKEVGGRAIKLPVSAPFHCSMLQPAAEKLEDELNKISINKLNGIVMSNVKGEAYLEDDN
HHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHEEHHHHCCEEEECCCCCEEECCCH
IIELLTSQVKKPVLFINDIEKMIESGVDTFIEIGPGKALSGFVKKINKNVTVLNVEDLKS
HHHHHHHHHHCCEEHHHHHHHHHHCCCHHEEECCCCHHHHHHHHHHCCCEEEEEHHHHHH
LEKTLSKLREMEVL
HHHHHHHHHHHCCC
>Mature Secondary Structure 
AKLGFLFAGQGAQYVGMGKEFFDNFEESKEVFKRSSEALGIDMEELCFSDPEGLLNKTE
CCEEEEEECCCCCEECCCHHHHHHHHHHHHHHHHCCHHCCCCHHHHHCCCCHHHCCCCC
FTQPAIITTNMAILTALDKLGVKSHISCGLSLGEYSALIHSGAINFEDGVKLVKKRGKFM
CCCCEEEEHHHHHHHHHHHHCCHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
QEAVAEGIGGMVAVLRMTPEQVDEIIEKSSPYGIVEGANYNSPGQIVISGELVALEKAME
HHHHHHCHHHHHHHHHCCHHHHHHHHHCCCCCEEEECCCCCCCCEEEEECHHHHHHHHHH
FIKEVGGRAIKLPVSAPFHCSMLQPAAEKLEDELNKISINKLNGIVMSNVKGEAYLEDDN
HHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHEEHHHHCCEEEECCCCCEEECCCH
IIELLTSQVKKPVLFINDIEKMIESGVDTFIEIGPGKALSGFVKKINKNVTVLNVEDLKS
HHHHHHHHHHCCEEHHHHHHHHHHCCCHHEEECCCCHHHHHHHHHHCCCEEEEEHHHHHH
LEKTLSKLREMEVL
HHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8759840; 9534248; 9384377 [H]