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The map label for this gene is 18310048

Identifier: 18310048

GI number: 18310048

Start: 1273220

End: 1273720

Strand: Direct

Name: 18310048

Synonym: CPE1066

Alternate gene names: NA

Gene position: 1273220-1273720 (Clockwise)

Preceding gene: 18310047

Following gene: 18310049

Centisome position: 42.0

GC content: 30.14

Gene sequence:

>501_bases
ATGATTAGCAAAAGAGAAGATTATATTTCGTGGGATGAGTATTTTATGGGAGTGGCATTAATTAGTGCCAAAAGAAGCAA
AGACCCAAATACCCAAGTTGGAGCTTGCATAGTTGATAATGATAATAAAATAGTAGGTATTGGATACAATGGCTTTCCTA
AGGGATGTTCAGATGATGATTTACCTTGGGGAAATAAGGGAGATTTTTTAGAAACAAAATATCCATATGCATGTCATGCT
GAACTTAATGCTATTTTAAATAGTACAGGTAAGAATGTTAAAAACTGCAGAGTATATGCAACTTTATTTCCTTGTAATGA
ATGTGCTAAAGCAATAATTCAAGCTGGGATAACTGAAGTAATATACCTTTCAGATAAATATAAAGATACTGATATTGTTA
AGGCATCTAAATTTATGTTTGATAAAGCAAATGTAAAATATAGATATTTAGGAAGCGATAGAGATAATTTATTAATATCA
TTTAAGCCAGAAGATGTTTAA

Upstream 100 bases:

>100_bases
TAAATTTAAGAAAGAAATAACAATGAATTTTTTTAAAACACTTGAAAAAAAATAAAAAAACTTTAAAATTAGTGTTAAGT
TTCTATTTAGGAGGGTTAAT

Downstream 100 bases:

>100_bases
AATAAATAAACCCCATAGTATTATCTATGGGGTTTATTTTAAGAGAAAGTTTATAATAGTTGACAATTTTTATTTAGTAT
AGTATATTTTGAATATCAAA

Product: cytidine/deoxycytidylate deaminase family protein

Products: dUMP; NH3

Alternate protein names: NA

Number of amino acids: Translated: 166; Mature: 166

Protein sequence:

>166_residues
MISKREDYISWDEYFMGVALISAKRSKDPNTQVGACIVDNDNKIVGIGYNGFPKGCSDDDLPWGNKGDFLETKYPYACHA
ELNAILNSTGKNVKNCRVYATLFPCNECAKAIIQAGITEVIYLSDKYKDTDIVKASKFMFDKANVKYRYLGSDRDNLLIS
FKPEDV

Sequences:

>Translated_166_residues
MISKREDYISWDEYFMGVALISAKRSKDPNTQVGACIVDNDNKIVGIGYNGFPKGCSDDDLPWGNKGDFLETKYPYACHA
ELNAILNSTGKNVKNCRVYATLFPCNECAKAIIQAGITEVIYLSDKYKDTDIVKASKFMFDKANVKYRYLGSDRDNLLIS
FKPEDV
>Mature_166_residues
MISKREDYISWDEYFMGVALISAKRSKDPNTQVGACIVDNDNKIVGIGYNGFPKGCSDDDLPWGNKGDFLETKYPYACHA
ELNAILNSTGKNVKNCRVYATLFPCNECAKAIIQAGITEVIYLSDKYKDTDIVKASKFMFDKANVKYRYLGSDRDNLLIS
FKPEDV

Specific function: Unknown

COG id: COG2131

COG function: function code F; Deoxycytidylate deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI61742819, Length=159, Percent_Identity=59.748427672956, Blast_Score=206, Evalue=6e-54,
Organism=Homo sapiens, GI61742821, Length=159, Percent_Identity=59.748427672956, Blast_Score=206, Evalue=8e-54,
Organism=Caenorhabditis elegans, GI17557019, Length=149, Percent_Identity=42.9530201342282, Blast_Score=127, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6321938, Length=132, Percent_Identity=34.0909090909091, Blast_Score=78, Evalue=7e-16,
Organism=Drosophila melanogaster, GI24667298, Length=164, Percent_Identity=56.7073170731707, Blast_Score=191, Evalue=2e-49,
Organism=Drosophila melanogaster, GI24667302, Length=164, Percent_Identity=56.7073170731707, Blast_Score=191, Evalue=2e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR015517
- InterPro:   IPR016193
- InterPro:   IPR016473 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: 3.5.4.12

Molecular weight: Translated: 18667; Mature: 18667

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
3.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISKREDYISWDEYFMGVALISAKRSKDPNTQVGACIVDNDNKIVGIGYNGFPKGCSDDD
CCCCCCCCCCHHHHHHHHHEEECCCCCCCCCCEEEEEECCCCEEEEECCCCCCCCCCCCC
LPWGNKGDFLETKYPYACHAELNAILNSTGKNVKNCRVYATLFPCNECAKAIIQAGITEV
CCCCCCCCEECCCCCEEEHHHHHHHHHCCCCCCCCEEEEEEEECHHHHHHHHHHCCCEEE
IYLSDKYKDTDIVKASKFMFDKANVKYRYLGSDRDNLLISFKPEDV
EEECCCCCCCCCEEHHHHEEECCCEEEEEECCCCCCEEEEECCCCC
>Mature Secondary Structure
MISKREDYISWDEYFMGVALISAKRSKDPNTQVGACIVDNDNKIVGIGYNGFPKGCSDDD
CCCCCCCCCCHHHHHHHHHEEECCCCCCCCCCEEEEEECCCCEEEEECCCCCCCCCCCCC
LPWGNKGDFLETKYPYACHAELNAILNSTGKNVKNCRVYATLFPCNECAKAIIQAGITEV
CCCCCCCCEECCCCCEEEHHHHHHHHHCCCCCCCCEEEEEEEECHHHHHHHHHHCCCEEE
IYLSDKYKDTDIVKASKFMFDKANVKYRYLGSDRDNLLISFKPEDV
EEECCCCCCCCCEEHHHHEEECCCEEEEEECCCCCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: dCMP; H2O

Specific reaction: dCMP + H2O = dUMP + NH3

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8329441 [H]