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The map label for this gene is hisB [H]

Identifier: 18309954

GI number: 18309954

Start: 1171854

End: 1172639

Strand: Direct

Name: hisB [H]

Synonym: CPE0972

Alternate gene names: 18309954

Gene position: 1171854-1172639 (Clockwise)

Preceding gene: 18309951

Following gene: 18309957

Centisome position: 38.66

GC content: 29.52

Gene sequence:

>786_bases
ATGAGAAGCAATTATCATACACATACATATAGATGTAATCATGCCACAGGAACTATTGAAGATTATGTTAAAGAAGCTAT
AAAAGCTAATATAGATGAAATTGGAATTTCTGATCACTTACCACATCCAGGTAAGAATATAGATAATTATCACAGAATGG
CTTATGAAGATTTAGAGGATTACTTTGGAAAGATAGAAGAAGCTATAGAAAAGTATGGAGATAAAATATCAATAAAAAGA
TCCATAGAATGCGAGTATTTCCCAGACTTCGGATGGCTTTATGAAGAGCTAAAGGATAAATATAAGGCAGATTATTTAGC
TTTAGGAGTACATTTCTTCCCTTATAAAGGAGAATGGGTATATGTTGGAACAATAGAATTAACGCCAGAAATCCTAATGA
TTTATGCTGATTTTGTAGTGGAAGCAATTAAGAGTGGATATTTTTCATATTTAGCACATCCAGATTTATTTGGAATGACA
TATAAAAATTGGGATGAACGTGCAGAAGAGGCCTCAAAGAGAATTTTAAAAGCTGCTGAAGAAATGAATATGCCTATAGA
GATAAATGTAAATGGAATGAGAAAAAATAAAATTTCTTATAATAATGGAGAAAGATATCAATATCCAATAAAAGAGTTTT
GGGAATTATCTAAGGAATATAATGTTAAAAGAATAGTTGGAATTGATGCTCATAATCCAGAAGAAATGCATGATTTAGAT
ATGGGGTTAAACTTTGCTAAAGAACATGATTTAACTATTATAGATAGATTAGAAGTTAATAAATAA

Upstream 100 bases:

>100_bases
AAGAGATAATAGATTTATAGAATGGAAATCTAATGTTGGTCAAATTTTTATAATTAGATACAATAGTAAATGAATGTTTA
AATACATAGGAGGAGTTTTA

Downstream 100 bases:

>100_bases
AAAATAGGAGCTTAGTTAAGCTCCTATTTTTTATTTATATGTTGTTTTACTTGATGGCTCATTGGATTCATATGGAGTAT
TTTCATTAGCTTTATTTTTA

Product: histidinol phosphatase

Products: NA

Alternate protein names: HolPase [H]

Number of amino acids: Translated: 261; Mature: 261

Protein sequence:

>261_residues
MRSNYHTHTYRCNHATGTIEDYVKEAIKANIDEIGISDHLPHPGKNIDNYHRMAYEDLEDYFGKIEEAIEKYGDKISIKR
SIECEYFPDFGWLYEELKDKYKADYLALGVHFFPYKGEWVYVGTIELTPEILMIYADFVVEAIKSGYFSYLAHPDLFGMT
YKNWDERAEEASKRILKAAEEMNMPIEINVNGMRKNKISYNNGERYQYPIKEFWELSKEYNVKRIVGIDAHNPEEMHDLD
MGLNFAKEHDLTIIDRLEVNK

Sequences:

>Translated_261_residues
MRSNYHTHTYRCNHATGTIEDYVKEAIKANIDEIGISDHLPHPGKNIDNYHRMAYEDLEDYFGKIEEAIEKYGDKISIKR
SIECEYFPDFGWLYEELKDKYKADYLALGVHFFPYKGEWVYVGTIELTPEILMIYADFVVEAIKSGYFSYLAHPDLFGMT
YKNWDERAEEASKRILKAAEEMNMPIEINVNGMRKNKISYNNGERYQYPIKEFWELSKEYNVKRIVGIDAHNPEEMHDLD
MGLNFAKEHDLTIIDRLEVNK
>Mature_261_residues
MRSNYHTHTYRCNHATGTIEDYVKEAIKANIDEIGISDHLPHPGKNIDNYHRMAYEDLEDYFGKIEEAIEKYGDKISIKR
SIECEYFPDFGWLYEELKDKYKADYLALGVHFFPYKGEWVYVGTIELTPEILMIYADFVVEAIKSGYFSYLAHPDLFGMT
YKNWDERAEEASKRILKAAEEMNMPIEINVNGMRKNKISYNNGERYQYPIKEFWELSKEYNVKRIVGIDAHNPEEMHDLD
MGLNFAKEHDLTIIDRLEVNK

Specific function: Unknown

COG id: COG1387

COG function: function code ER; Histidinol phosphatase and related hydrolases of the PHP family

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PHP hydrolase family. HisK subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010140
- InterPro:   IPR004013
- InterPro:   IPR016195 [H]

Pfam domain/function: PF02811 PHP [H]

EC number: =3.1.3.15 [H]

Molecular weight: Translated: 30815; Mature: 30815

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSNYHTHTYRCNHATGTIEDYVKEAIKANIDEIGISDHLPHPGKNIDNYHRMAYEDLED
CCCCCCCCEEEECCCCCCHHHHHHHHHHCCHHHCCCCCCCCCCCCCCHHHHHHHHHHHHH
YFGKIEEAIEKYGDKISIKRSIECEYFPDFGWLYEELKDKYKADYLALGVHFFPYKGEWV
HHHHHHHHHHHCCCEEEEEEEECEEECCCHHHHHHHHHHHHCCCEEEEEEEEECCCCCEE
YVGTIELTPEILMIYADFVVEAIKSGYFSYLAHPDLFGMTYKNWDERAEEASKRILKAAE
EEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
EMNMPIEINVNGMRKNKISYNNGERYQYPIKEFWELSKEYNVKRIVGIDAHNPEEMHDLD
HCCCCEEEEECCEECCCCCCCCCCEEECCHHHHHHHHHHCCCEEEEEECCCCHHHHHHHH
MGLNFAKEHDLTIIDRLEVNK
HCCCCCCCCCCEEEEEEECCC
>Mature Secondary Structure
MRSNYHTHTYRCNHATGTIEDYVKEAIKANIDEIGISDHLPHPGKNIDNYHRMAYEDLED
CCCCCCCCEEEECCCCCCHHHHHHHHHHCCHHHCCCCCCCCCCCCCCHHHHHHHHHHHHH
YFGKIEEAIEKYGDKISIKRSIECEYFPDFGWLYEELKDKYKADYLALGVHFFPYKGEWV
HHHHHHHHHHHCCCEEEEEEEECEEECCCHHHHHHHHHHHHCCCEEEEEEEEECCCCCEE
YVGTIELTPEILMIYADFVVEAIKSGYFSYLAHPDLFGMTYKNWDERAEEASKRILKAAE
EEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
EMNMPIEINVNGMRKNKISYNNGERYQYPIKEFWELSKEYNVKRIVGIDAHNPEEMHDLD
HCCCCEEEEECCEECCCCCCCCCCEEECCHHHHHHHHHHCCCEEEEEECCCCHHHHHHHH
MGLNFAKEHDLTIIDRLEVNK
HCCCCCCCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10567266 [H]