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The map label for this gene is ycbM [H]

Identifier: 18309933

GI number: 18309933

Start: 1149399

End: 1150304

Strand: Direct

Name: ycbM [H]

Synonym: CPE0951

Alternate gene names: 18309933

Gene position: 1149399-1150304 (Clockwise)

Preceding gene: 18309932

Following gene: 18309935

Centisome position: 37.92

GC content: 26.16

Gene sequence:

>906_bases
TTGGAAGGATTTATAATAGGATTGTCTTTGACAATCCTTATTGTGCTTTTAATAATATTTATTTTAAAAACTAAAGAAAT
AAATAGATTAACCTTGGAGTTAAAAAAGTTAAATAGTGAGGGGAAAATAGAAAAATTAAGATTATCACTTCCAAATAAAA
ATATTGAAAATTTAATAGTAGAGATAAATACATTAATAGATGATAAAAGAAAAATGGAGAATATTTATAAGGAAAAGGAC
ATGGAGTTAAGAGAAGCCATTGCAAATATGTCTCATGATTTAAGAACTCCTTTAACTTCTATAATGGGATATGTTTATTT
ATTAAATGATGATAAATTAGATAAAGAGGAAAGAAAAGAATATTTAAAAATAATAGAAAAAAGATCTTTAGTTTTAAATG
ATTTAATAACTAATTTTTATGGACTGTCTAGAATACAAGCAGATCAGTATGAAATTAAATTTGAACCTGTTAATTTAGAA
GTGGTATTGGGTGAAATTATTGCAGCTTTTTATGAAACCTTAGATTATAAGTTTGGAGAACCAGAAATTAATATTGAAGA
GGGATTGGGACCTGTATTAGGTGATAAACAGGCTTTAAATAGAATATTTACTAATTTAATTGAAAACATCATAAAGCATG
GTGAAGGGGAAGTAAAAATATCCTTAAAGAAGAAAAATAAATACATAGTAATGGAATTTGCTAATAAAGCAGAAGAATTA
GAACCTAAGGATATAAATAGAATCTTTGAGAAGTTCTTTACTAAGGATAGAATGAGAACAGGGCAAAATACTGGCTTAGG
GCTAGCCATAGTTAAACTATTAGTAGAAAAGCAAGGACAAAAGATAGAGGCTAAAAAGGTTGGAAATAGGCTTGTTATAA
ATATAATATGGAGTTTAGAAAGTTAA

Upstream 100 bases:

>100_bases
GGAACTAATATTATAGTAGGAATAATAAATACAGTAGTATTTTTAATTTTAGGAATTTTAATAATAAGAAAACAAGAAGT
TAAATAAAGGAGGAGGTATA

Downstream 100 bases:

>100_bases
AAGTATTTAGACTTTTGAAAGAATAGAAAAATTAATTTTTAAAAGTATAAAATAAGCAATTTGAAATTAAATTGCTTATT
TTTTTTAATAAATATAATTC

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MEGFIIGLSLTILIVLLIIFILKTKEINRLTLELKKLNSEGKIEKLRLSLPNKNIENLIVEINTLIDDKRKMENIYKEKD
MELREAIANMSHDLRTPLTSIMGYVYLLNDDKLDKEERKEYLKIIEKRSLVLNDLITNFYGLSRIQADQYEIKFEPVNLE
VVLGEIIAAFYETLDYKFGEPEINIEEGLGPVLGDKQALNRIFTNLIENIIKHGEGEVKISLKKKNKYIVMEFANKAEEL
EPKDINRIFEKFFTKDRMRTGQNTGLGLAIVKLLVEKQGQKIEAKKVGNRLVINIIWSLES

Sequences:

>Translated_301_residues
MEGFIIGLSLTILIVLLIIFILKTKEINRLTLELKKLNSEGKIEKLRLSLPNKNIENLIVEINTLIDDKRKMENIYKEKD
MELREAIANMSHDLRTPLTSIMGYVYLLNDDKLDKEERKEYLKIIEKRSLVLNDLITNFYGLSRIQADQYEIKFEPVNLE
VVLGEIIAAFYETLDYKFGEPEINIEEGLGPVLGDKQALNRIFTNLIENIIKHGEGEVKISLKKKNKYIVMEFANKAEEL
EPKDINRIFEKFFTKDRMRTGQNTGLGLAIVKLLVEKQGQKIEAKKVGNRLVINIIWSLES
>Mature_301_residues
MEGFIIGLSLTILIVLLIIFILKTKEINRLTLELKKLNSEGKIEKLRLSLPNKNIENLIVEINTLIDDKRKMENIYKEKD
MELREAIANMSHDLRTPLTSIMGYVYLLNDDKLDKEERKEYLKIIEKRSLVLNDLITNFYGLSRIQADQYEIKFEPVNLE
VVLGEIIAAFYETLDYKFGEPEINIEEGLGPVLGDKQALNRIFTNLIENIIKHGEGEVKISLKKKNKYIVMEFANKAEEL
EPKDINRIFEKFFTKDRMRTGQNTGLGLAIVKLLVEKQGQKIEAKKVGNRLVINIIWSLES

Specific function: Member of the two-component regulatory system ycbM/ycbL. Probably activates ycbL by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1786600, Length=203, Percent_Identity=28.5714285714286, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1786912, Length=203, Percent_Identity=29.064039408867, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788393, Length=228, Percent_Identity=25, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1789149, Length=262, Percent_Identity=27.4809160305344, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI145693157, Length=248, Percent_Identity=26.6129032258064, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1788713, Length=231, Percent_Identity=25.974025974026, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1790346, Length=222, Percent_Identity=26.1261261261261, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1789808, Length=200, Percent_Identity=29.5, Blast_Score=66, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 34842; Mature: 34842

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEGFIIGLSLTILIVLLIIFILKTKEINRLTLELKKLNSEGKIEKLRLSLPNKNIENLIV
CCCEEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHH
EINTLIDDKRKMENIYKEKDMELREAIANMSHDLRTPLTSIMGYVYLLNDDKLDKEERKE
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHH
YLKIIEKRSLVLNDLITNFYGLSRIQADQYEIKFEPVNLEVVLGEIIAAFYETLDYKFGE
HHHHHHHHHHHHHHHHHHHHHHHHEECCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCCC
PEINIEEGLGPVLGDKQALNRIFTNLIENIIKHGEGEVKISLKKKNKYIVMEFANKAEEL
CCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCEEEEEECCHHHCC
EPKDINRIFEKFFTKDRMRTGQNTGLGLAIVKLLVEKQGQKIEAKKVGNRLVINIIWSLE
CHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCEEHHHHCCCEEEEEEEEECC
S
C
>Mature Secondary Structure
MEGFIIGLSLTILIVLLIIFILKTKEINRLTLELKKLNSEGKIEKLRLSLPNKNIENLIV
CCCEEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHH
EINTLIDDKRKMENIYKEKDMELREAIANMSHDLRTPLTSIMGYVYLLNDDKLDKEERKE
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHH
YLKIIEKRSLVLNDLITNFYGLSRIQADQYEIKFEPVNLEVVLGEIIAAFYETLDYKFGE
HHHHHHHHHHHHHHHHHHHHHHHHEECCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCCC
PEINIEEGLGPVLGDKQALNRIFTNLIENIIKHGEGEVKISLKKKNKYIVMEFANKAEEL
CCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCEEEEEECCHHHCC
EPKDINRIFEKFFTKDRMRTGQNTGLGLAIVKLLVEKQGQKIEAKKVGNRLVINIIWSLE
CHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCEEHHHHCCCEEEEEEEEECC
S
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7704254; 9384377 [H]