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The map label for this gene is nrdD [C]

Identifier: 18309899

GI number: 18309899

Start: 1117404

End: 1119164

Strand: Direct

Name: nrdD [C]

Synonym: CPE0917

Alternate gene names: 18309899

Gene position: 1117404-1119164 (Clockwise)

Preceding gene: 18309898

Following gene: 18309900

Centisome position: 36.86

GC content: 29.3

Gene sequence:

>1761_bases
ATGTTATCTAGTAAGAAAATAGTAGATGATTATATTAAAAAAATAGATTGGAGAGTCAATGAAAATTCCAATTCACCATA
TAGTTTTGGGAGTCTCAATAAACATATAATAGCTGAGGTTTCTAAAGATTACTGGCTTAATGAAGTTTATAAAGATAAAA
GAATAATAGATGCTTATAAAAATGGAGATATGCATATTCATGACCTAGGAGGATTAACACTTTATTGTTGTGGATATTCC
TTAAGAAACATAATTTTAATGGGAGTACAGGGAATTCCTAATATTCCAACTAGTAGTCCTGCAAAACATTTTGATGCTAT
ATTAAATCAAATAGCTAATTTGGTTACAATATATCAAAATGAGATTATGGGAGCCGTTGCTTTTAATTCATTTGATACAT
TATTAGCACCTTATATAAAGAAGGATAATTTAACATATGAAGAGGTTAAACAAAATTTACAAAACTTTATATTTAGTATA
AATAGTAATAGTAGGGCAGGAGCTGAACCAGCTTTCACTAATATTACCTTTGATCTTTTTCCACCAAAAGACTTAGAGAA
TGACCCTGCTTTAATTGGAGATAAAATTCAAGAGTTCACATATAAGGAATGTCAAAAAGAAATGGACATGTTAAATAAGG
CATTTTATGAACTTATGAATGAGGGAGATTATAATGGAAGACCATTTTCTTATCCAATACCAACTTATAATATAAACAGT
AATTTTGATTTTGATAACCCTAATAATGATATGTTATTTGAGATGACAGGAAAGTTTGGGTATCCTTACTTTGCAAACTT
TGTTAATTCAGATATGGATCAAAGTGATGTAAGATCAATGTGTTGTAGATTAAATCTTGATTTAAGAGAGCTTAGAAAGA
GAAATGGTGGTCTTTTTGGAAGTGGAGATAGTACAGGAAGTATAGGTGTTGTTACAATAAATTTACCAAGATTGGCATAT
AAGTATAAAAATAACGAAAAAGAGTTTTTTAATGCTTTAAAAGAAATATTGATTATAGCAAAAGATAGCTTAGAAAAGAA
GAGAAAATGGTTAAATGACAATATTATAAATAAAGATATGTTGCCGGCATTTTCAACTTATGTAGGGACTTTGAAAAATC
ATTTTAGTACTATAGGAATAGTTGGATTAAATGAGATGTGTGAAAACTTTAATGGAAATAATATATTAACTGAAGAAGGA
ATGGAGTTTTCAATAAAGGTTTGTAATTTCATAAGAGAAGAATTAATAAACTTTCAAGAAGAAACAGGAAATCTTTATAA
TTTTGAGGCTACTCCAGCTGAATCAACTTGTTATAGACTAGCTAAAAAGGATGTAGAGGACTTTGAGGATATTATAGTTA
GAGGGGGAAGAGAATATCCATACTATACAAACTCATGTCATATGCCACCTAATGAAGTTAAAAACTTAAAGCAATTATTT
GATCACCAAGATAAGCTTCAAGTGTTATTCACAGGAGGAACTGTGGTGCATATTTATTGTGATGGAGCTATAAGTGGAGA
AAAGGCAAAACACATAGTAAAGACAGTTTGTAAGAAATATAGAACACCTTATGTAAGTATTTCTCCTTTAAATAGATACT
GTGAAGAGCATGGATATGTAAAGGAAAGGGTAGAAGAGTGTCCTATATGTGGCAAAAAGCTAGATTTATATCAAAGAATA
ACAGGCTACTTAAGAAAAGTTGAATTCTTTAATGATGGTAAAAAATCAGAGTTTAAGGATAGAAATCAGTTAAGCCTATG
A

Upstream 100 bases:

>100_bases
GATTATAAACATATAGGTATATGAGTATTTATTATAATACTTTGAACTGATGTATAATGTCAGTATAAATAAAAGGGATG
TAAAAAAGGATGTGAAAAAT

Downstream 100 bases:

>100_bases
TTATAAAAACAAAGGGCATTGTTCATGAGAGAGTAGAGGATGCGCCTTTTATGGGAGCATTAATAAGTGCAGTAGATTTT
AACTTAAACTGCAAAGGATG

Product: anaerobic ribonucleoside triphosphate reductase

Products: ribonucleoside triphosphate; thioredoxin

Alternate protein names: NA

Number of amino acids: Translated: 586; Mature: 586

Protein sequence:

>586_residues
MLSSKKIVDDYIKKIDWRVNENSNSPYSFGSLNKHIIAEVSKDYWLNEVYKDKRIIDAYKNGDMHIHDLGGLTLYCCGYS
LRNIILMGVQGIPNIPTSSPAKHFDAILNQIANLVTIYQNEIMGAVAFNSFDTLLAPYIKKDNLTYEEVKQNLQNFIFSI
NSNSRAGAEPAFTNITFDLFPPKDLENDPALIGDKIQEFTYKECQKEMDMLNKAFYELMNEGDYNGRPFSYPIPTYNINS
NFDFDNPNNDMLFEMTGKFGYPYFANFVNSDMDQSDVRSMCCRLNLDLRELRKRNGGLFGSGDSTGSIGVVTINLPRLAY
KYKNNEKEFFNALKEILIIAKDSLEKKRKWLNDNIINKDMLPAFSTYVGTLKNHFSTIGIVGLNEMCENFNGNNILTEEG
MEFSIKVCNFIREELINFQEETGNLYNFEATPAESTCYRLAKKDVEDFEDIIVRGGREYPYYTNSCHMPPNEVKNLKQLF
DHQDKLQVLFTGGTVVHIYCDGAISGEKAKHIVKTVCKKYRTPYVSISPLNRYCEEHGYVKERVEECPICGKKLDLYQRI
TGYLRKVEFFNDGKKSEFKDRNQLSL

Sequences:

>Translated_586_residues
MLSSKKIVDDYIKKIDWRVNENSNSPYSFGSLNKHIIAEVSKDYWLNEVYKDKRIIDAYKNGDMHIHDLGGLTLYCCGYS
LRNIILMGVQGIPNIPTSSPAKHFDAILNQIANLVTIYQNEIMGAVAFNSFDTLLAPYIKKDNLTYEEVKQNLQNFIFSI
NSNSRAGAEPAFTNITFDLFPPKDLENDPALIGDKIQEFTYKECQKEMDMLNKAFYELMNEGDYNGRPFSYPIPTYNINS
NFDFDNPNNDMLFEMTGKFGYPYFANFVNSDMDQSDVRSMCCRLNLDLRELRKRNGGLFGSGDSTGSIGVVTINLPRLAY
KYKNNEKEFFNALKEILIIAKDSLEKKRKWLNDNIINKDMLPAFSTYVGTLKNHFSTIGIVGLNEMCENFNGNNILTEEG
MEFSIKVCNFIREELINFQEETGNLYNFEATPAESTCYRLAKKDVEDFEDIIVRGGREYPYYTNSCHMPPNEVKNLKQLF
DHQDKLQVLFTGGTVVHIYCDGAISGEKAKHIVKTVCKKYRTPYVSISPLNRYCEEHGYVKERVEECPICGKKLDLYQRI
TGYLRKVEFFNDGKKSEFKDRNQLSL
>Mature_586_residues
MLSSKKIVDDYIKKIDWRVNENSNSPYSFGSLNKHIIAEVSKDYWLNEVYKDKRIIDAYKNGDMHIHDLGGLTLYCCGYS
LRNIILMGVQGIPNIPTSSPAKHFDAILNQIANLVTIYQNEIMGAVAFNSFDTLLAPYIKKDNLTYEEVKQNLQNFIFSI
NSNSRAGAEPAFTNITFDLFPPKDLENDPALIGDKIQEFTYKECQKEMDMLNKAFYELMNEGDYNGRPFSYPIPTYNINS
NFDFDNPNNDMLFEMTGKFGYPYFANFVNSDMDQSDVRSMCCRLNLDLRELRKRNGGLFGSGDSTGSIGVVTINLPRLAY
KYKNNEKEFFNALKEILIIAKDSLEKKRKWLNDNIINKDMLPAFSTYVGTLKNHFSTIGIVGLNEMCENFNGNNILTEEG
MEFSIKVCNFIREELINFQEETGNLYNFEATPAESTCYRLAKKDVEDFEDIIVRGGREYPYYTNSCHMPPNEVKNLKQLF
DHQDKLQVLFTGGTVVHIYCDGAISGEKAKHIVKTVCKKYRTPYVSISPLNRYCEEHGYVKERVEECPICGKKLDLYQRI
TGYLRKVEFFNDGKKSEFKDRNQLSL

Specific function: Unknown

COG id: COG1328

COG function: function code F; Oxygen-sensitive ribonucleoside-triphosphate reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 DOD-type homing endonuclease domains [H]

Homologues:

Organism=Escherichia coli, GI1790686, Length=624, Percent_Identity=21.6346153846154, Blast_Score=100, Evalue=4e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005144
- InterPro:   IPR003586
- InterPro:   IPR003587
- InterPro:   IPR007869
- InterPro:   IPR006142
- InterPro:   IPR004042
- InterPro:   IPR006141
- InterPro:   IPR012833 [H]

Pfam domain/function: PF03477 ATP-cone; PF05204 Hom_end [H]

EC number: 1.17.4.2

Molecular weight: Translated: 67449; Mature: 67449

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSSKKIVDDYIKKIDWRVNENSNSPYSFGSLNKHIIAEVSKDYWLNEVYKDKRIIDAYK
CCCCCHHHHHHHHHHCCEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
NGDMHIHDLGGLTLYCCGYSLRNIILMGVQGIPNIPTSSPAKHFDAILNQIANLVTIYQN
CCCEEEEECCCEEEEEHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
EIMGAVAFNSFDTLLAPYIKKDNLTYEEVKQNLQNFIFSINSNSRAGAEPAFTNITFDLF
HHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHEEECCCCCCCCCCCCCCEEEEECC
PPKDLENDPALIGDKIQEFTYKECQKEMDMLNKAFYELMNEGDYNGRPFSYPIPTYNINS
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCEEECCC
NFDFDNPNNDMLFEMTGKFGYPYFANFVNSDMDQSDVRSMCCRLNLDLRELRKRNGGLFG
CCCCCCCCCCEEEEECCCCCCHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHCCCEEC
SGDSTGSIGVVTINLPRLAYKYKNNEKEFFNALKEILIIAKDSLEKKRKWLNDNIINKDM
CCCCCCCEEEEEEECCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
LPAFSTYVGTLKNHFSTIGIVGLNEMCENFNGNNILTEEGMEFSIKVCNFIREELINFQE
HHHHHHHHHHHHHHHHHEEEEEHHHHHHCCCCCEEEECCCCEEHHHHHHHHHHHHHHHHH
ETGNLYNFEATPAESTCYRLAKKDVEDFEDIIVRGGREYPYYTNSCHMPPNEVKNLKQLF
HCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHH
DHQDKLQVLFTGGTVVHIYCDGAISGEKAKHIVKTVCKKYRTPYVSISPLNRYCEEHGYV
CCCCCEEEEEECCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEECHHHHHHHHCCHH
KERVEECPICGKKLDLYQRITGYLRKVEFFNDGKKSEFKDRNQLSL
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLSSKKIVDDYIKKIDWRVNENSNSPYSFGSLNKHIIAEVSKDYWLNEVYKDKRIIDAYK
CCCCCHHHHHHHHHHCCEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
NGDMHIHDLGGLTLYCCGYSLRNIILMGVQGIPNIPTSSPAKHFDAILNQIANLVTIYQN
CCCEEEEECCCEEEEEHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
EIMGAVAFNSFDTLLAPYIKKDNLTYEEVKQNLQNFIFSINSNSRAGAEPAFTNITFDLF
HHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHEEECCCCCCCCCCCCCCEEEEECC
PPKDLENDPALIGDKIQEFTYKECQKEMDMLNKAFYELMNEGDYNGRPFSYPIPTYNINS
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCEEECCC
NFDFDNPNNDMLFEMTGKFGYPYFANFVNSDMDQSDVRSMCCRLNLDLRELRKRNGGLFG
CCCCCCCCCCEEEEECCCCCCHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHCCCEEC
SGDSTGSIGVVTINLPRLAYKYKNNEKEFFNALKEILIIAKDSLEKKRKWLNDNIINKDM
CCCCCCCEEEEEEECCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
LPAFSTYVGTLKNHFSTIGIVGLNEMCENFNGNNILTEEGMEFSIKVCNFIREELINFQE
HHHHHHHHHHHHHHHHHEEEEEHHHHHHCCCCCEEEECCCCEEHHHHHHHHHHHHHHHHH
ETGNLYNFEATPAESTCYRLAKKDVEDFEDIIVRGGREYPYYTNSCHMPPNEVKNLKQLF
HCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHH
DHQDKLQVLFTGGTVVHIYCDGAISGEKAKHIVKTVCKKYRTPYVSISPLNRYCEEHGYV
CCCCCEEEEEECCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEECHHHHHHHHCCHH
KERVEECPICGKKLDLYQRITGYLRKVEFFNDGKKSEFKDRNQLSL
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Ca2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2'-deoxyribonucleoside triphosphate; thioredoxin disulfide; H2O

Specific reaction: 2'-deoxyribonucleoside triphosphate + thioredoxin disulfide + H2O = ribonucleoside triphosphate + thioredoxin

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]