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The map label for this gene is tctD [H]

Identifier: 17548109

GI number: 17548109

Start: 3657231

End: 3657905

Strand: Direct

Name: tctD [H]

Synonym: RSc3392

Alternate gene names: 17548109

Gene position: 3657231-3657905 (Clockwise)

Preceding gene: 17548107

Following gene: 17548115

Centisome position: 98.41

GC content: 65.93

Gene sequence:

>675_bases
ATGAAGCTGCTCCTGATCGAGGACAACGCACCCCTGGCGCAGTGGTTGTCCGAAGCCCTGCGCCGTGCGCAGTTTACGGT
CGATCATGCCAGTGATGGCGAATCGGCCGATACCCTGTTGCTGACGCAGCACTACGACGTCGTGCTGCTTGACCTGCAGT
TGCCGTCGCTGTCCGGCCGCGCCGTGCTGCAGCGTCTGCGCGATCGACGCAACGCCGTGCCGGTGATGATCCTGACCGCC
GCCGGCGGCATCGATGACAAGGTTGCCTGTCTGGGCGCCGGCGCGGACGACTATCTCGTCAAGCCGTTCGAGATCCGCGA
ACTGATCGCCCGCATCCAGGTACTGGTGCGCCGCAACACGCCGGCCAACGCGGTCGAGCTGCAGTGCGGTGACCTGTCCT
ATCACACCGGCAGCCGCACGTTTGCGCTGTCCGGCCGGCCGCTGGTGCTGCCGGCGCGCGAACACACCGTGCTGGAGATC
CTGATGCTCAAGCTCGGGCGCACGGTGTCCAAGCCGGCGCTGGTCAACGGCGTGTTCGGGCTGGAGGACGACGCCAGCCC
CGAGGCGATCGAGATCTACATCCATCGGCTGCGCAAGAAGCTCGAACATTCCGCTGCCACCATCGTTACCCTGCGCGGGC
TCGGCTATCTGTTGCGCGATGCGTCGACCCAGTAG

Upstream 100 bases:

>100_bases
CGTGTGATGCATCCGGCGCGCGCGGGCAGCCGCCTTTCATTCTAGGGGCACCGGCCCACGAACCGCTTTCGAAATCAACA
GGCCTGAGCGTCGCGTTCGC

Downstream 100 bases:

>100_bases
TCCGGCAGCGCCGGCGCCGCGCGCGCGCAGCCTGCGCCTGCGGCTGGCCCTGTGGCTGGCACTGCCGCTGGCCGTGTACG
TGGGCGCGGACGGCTGGCTC

Product: response regulator transcription regulator protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 224; Mature: 224

Protein sequence:

>224_residues
MKLLLIEDNAPLAQWLSEALRRAQFTVDHASDGESADTLLLTQHYDVVLLDLQLPSLSGRAVLQRLRDRRNAVPVMILTA
AGGIDDKVACLGAGADDYLVKPFEIRELIARIQVLVRRNTPANAVELQCGDLSYHTGSRTFALSGRPLVLPAREHTVLEI
LMLKLGRTVSKPALVNGVFGLEDDASPEAIEIYIHRLRKKLEHSAATIVTLRGLGYLLRDASTQ

Sequences:

>Translated_224_residues
MKLLLIEDNAPLAQWLSEALRRAQFTVDHASDGESADTLLLTQHYDVVLLDLQLPSLSGRAVLQRLRDRRNAVPVMILTA
AGGIDDKVACLGAGADDYLVKPFEIRELIARIQVLVRRNTPANAVELQCGDLSYHTGSRTFALSGRPLVLPAREHTVLEI
LMLKLGRTVSKPALVNGVFGLEDDASPEAIEIYIHRLRKKLEHSAATIVTLRGLGYLLRDASTQ
>Mature_224_residues
MKLLLIEDNAPLAQWLSEALRRAQFTVDHASDGESADTLLLTQHYDVVLLDLQLPSLSGRAVLQRLRDRRNAVPVMILTA
AGGIDDKVACLGAGADDYLVKPFEIRELIARIQVLVRRNTPANAVELQCGDLSYHTGSRTFALSGRPLVLPAREHTVLEI
LMLKLGRTVSKPALVNGVFGLEDDASPEAIEIYIHRLRKKLEHSAATIVTLRGLGYLLRDASTQ

Specific function: Transcriptional activator of the tctI tricarboxylate transport system operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790552, Length=218, Percent_Identity=39.4495412844037, Blast_Score=154, Evalue=4e-39,
Organism=Escherichia coli, GI1789402, Length=218, Percent_Identity=35.7798165137615, Blast_Score=147, Evalue=8e-37,
Organism=Escherichia coli, GI1786784, Length=221, Percent_Identity=35.2941176470588, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI87082012, Length=218, Percent_Identity=33.0275229357798, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1787375, Length=220, Percent_Identity=34.0909090909091, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1789809, Length=227, Percent_Identity=32.15859030837, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1786599, Length=220, Percent_Identity=33.1818181818182, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI2367329, Length=232, Percent_Identity=35.7758620689655, Blast_Score=100, Evalue=7e-23,
Organism=Escherichia coli, GI1786911, Length=220, Percent_Identity=31.8181818181818, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1790860, Length=224, Percent_Identity=31.25, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1788394, Length=220, Percent_Identity=29.0909090909091, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1787229, Length=228, Percent_Identity=28.0701754385965, Blast_Score=81, Evalue=4e-17,
Organism=Escherichia coli, GI1790863, Length=226, Percent_Identity=27.4336283185841, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788550, Length=107, Percent_Identity=32.7102803738318, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI145693140, Length=231, Percent_Identity=26.4069264069264, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1790299, Length=111, Percent_Identity=31.5315315315315, Blast_Score=64, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6322000, Length=130, Percent_Identity=33.8461538461538, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 24635; Mature: 24635

Theoretical pI: Translated: 7.15; Mature: 7.15

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLLLIEDNAPLAQWLSEALRRAQFTVDHASDGESADTLLLTQHYDVVLLDLQLPSLSGR
CEEEEEECCCCHHHHHHHHHHHHEEEEECCCCCCCCCEEEEEECCCEEEEEEECCCCCHH
AVLQRLRDRRNAVPVMILTAAGGIDDKVACLGAGADDYLVKPFEIRELIARIQVLVRRNT
HHHHHHHHHCCCCCEEEEEECCCCCCCEEEEECCCCCCEECCHHHHHHHHHHHHHHHCCC
PANAVELQCGDLSYHTGSRTFALSGRPLVLPAREHTVLEILMLKLGRTVSKPALVNGVFG
CCCEEEEEECCEEEECCCEEEEECCCEEEEECCCHHHHHHHHHHHCCCCCCCHHHCCEEC
LEDDASPEAIEIYIHRLRKKLEHSAATIVTLRGLGYLLRDASTQ
CCCCCCCHHHHHHHHHHHHHHHHHHHEEEEHHHHHHHHHCCCCC
>Mature Secondary Structure
MKLLLIEDNAPLAQWLSEALRRAQFTVDHASDGESADTLLLTQHYDVVLLDLQLPSLSGR
CEEEEEECCCCHHHHHHHHHHHHEEEEECCCCCCCCCEEEEEECCCEEEEEEECCCCCHH
AVLQRLRDRRNAVPVMILTAAGGIDDKVACLGAGADDYLVKPFEIRELIARIQVLVRRNT
HHHHHHHHHCCCCCEEEEEECCCCCCCEEEEECCCCCCEECCHHHHHHHHHHHHHHHCCC
PANAVELQCGDLSYHTGSRTFALSGRPLVLPAREHTVLEILMLKLGRTVSKPALVNGVFG
CCCEEEEEECCEEEECCCEEEEECCCEEEEECCCHHHHHHHHHHHCCCCCCCHHHCCEEC
LEDDASPEAIEIYIHRLRKKLEHSAATIVTLRGLGYLLRDASTQ
CCCCCCCHHHHHHHHHHHHHHHHHHHEEEEHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2666399; 11083839; 11677609 [H]