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The map label for this gene is tctD [H]

Identifier: 17547654

GI number: 17547654

Start: 3166348

End: 3167055

Strand: Direct

Name: tctD [H]

Synonym: RSc2935

Alternate gene names: 17547654

Gene position: 3166348-3167055 (Clockwise)

Preceding gene: 17547651

Following gene: 17547655

Centisome position: 85.2

GC content: 71.19

Gene sequence:

>708_bases
ATGCGGATCTTGCTGGTGGAGGATGAAGGGGAACTGGCGGCGTGGCTCGCGCGCGCGCTGGCGCAGAGCGGCTTCGTGGT
GGAGCGCGCGGCGGACGGGCTGGCGGCGGAAGCGTTCCTGGCCTCGGGCGAATTCGACGCCGTCGTGCTGGACCTGCGCC
TGCCGCGCAAGGACGGCTTTGCCGTGCTGGCCGACATGCGCGCGCGCGACGATCGCACGCCGGTGCTGATCCTGACGGCC
CAGGGCGCACTGGACGAGCGCGTGCGCGGCCTGAACGCCGGCGCCGACGACTTCCTCACCAAACCGTTTGCGCTGACGGA
GCTCGAAGCGCGGCTGATGGCGCTGATCCGCCGCAGCCGGGGCCGGGCGTTCCCGCGCCTGCGCTGCGGACCGCTGGAAT
TCGACACCGGCCGCAAGGCCTTCCTGCTGGCGGGCGAGCCGCTGTCGCTGACGCCGCGCGAGCACGCCGCGCTGTCCGCG
CTGCTGCACAAGACCGGGCAACCGATCAGCAAGGTCCATCTGTTCGACAAGGTGTTCAACCTGGACAGCGATTCCAGCCC
GGACGCCGTGGAAGTGGTCGTGCATCGCCTGCGCAAGAAGCTGGCGGGGTCCGGTGTGCAGATCGTCACGGTGCGCGGGC
TGGGCTACCTGCTCGAAGCCGAAGCGAGCGGCGTCCCGCAGGCGGCGGGCGACACATCCGCGCCATGA

Upstream 100 bases:

>100_bases
CGGCATGCGAATCGGCGCCGCGTCGAATTGGGTGAGGTCGTTGAACGGGCGCCAAGCATTATCATGAAAAAGCACTCAGA
ACGATATTGAGAGACACCCG

Downstream 100 bases:

>100_bases
CGCGACGCTTTGCCCTGCTGCCGCGCAGCCTCAAGCTGACGCTGCTGTGGCTCCTGCTGCCGGGGCTGGTCGGCGTGCTG
GCGATCGATACGCTGTCGGC

Product: response regulator transcription regulator protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 235; Mature: 235

Protein sequence:

>235_residues
MRILLVEDEGELAAWLARALAQSGFVVERAADGLAAEAFLASGEFDAVVLDLRLPRKDGFAVLADMRARDDRTPVLILTA
QGALDERVRGLNAGADDFLTKPFALTELEARLMALIRRSRGRAFPRLRCGPLEFDTGRKAFLLAGEPLSLTPREHAALSA
LLHKTGQPISKVHLFDKVFNLDSDSSPDAVEVVVHRLRKKLAGSGVQIVTVRGLGYLLEAEASGVPQAAGDTSAP

Sequences:

>Translated_235_residues
MRILLVEDEGELAAWLARALAQSGFVVERAADGLAAEAFLASGEFDAVVLDLRLPRKDGFAVLADMRARDDRTPVLILTA
QGALDERVRGLNAGADDFLTKPFALTELEARLMALIRRSRGRAFPRLRCGPLEFDTGRKAFLLAGEPLSLTPREHAALSA
LLHKTGQPISKVHLFDKVFNLDSDSSPDAVEVVVHRLRKKLAGSGVQIVTVRGLGYLLEAEASGVPQAAGDTSAP
>Mature_235_residues
MRILLVEDEGELAAWLARALAQSGFVVERAADGLAAEAFLASGEFDAVVLDLRLPRKDGFAVLADMRARDDRTPVLILTA
QGALDERVRGLNAGADDFLTKPFALTELEARLMALIRRSRGRAFPRLRCGPLEFDTGRKAFLLAGEPLSLTPREHAALSA
LLHKTGQPISKVHLFDKVFNLDSDSSPDAVEVVVHRLRKKLAGSGVQIVTVRGLGYLLEAEASGVPQAAGDTSAP

Specific function: Transcriptional activator of the tctI tricarboxylate transport system operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789402, Length=218, Percent_Identity=44.954128440367, Blast_Score=174, Evalue=5e-45,
Organism=Escherichia coli, GI1790552, Length=221, Percent_Identity=41.6289592760181, Blast_Score=170, Evalue=9e-44,
Organism=Escherichia coli, GI1786784, Length=223, Percent_Identity=34.5291479820628, Blast_Score=140, Evalue=6e-35,
Organism=Escherichia coli, GI1787375, Length=221, Percent_Identity=34.3891402714932, Blast_Score=130, Evalue=8e-32,
Organism=Escherichia coli, GI87082012, Length=218, Percent_Identity=31.651376146789, Blast_Score=124, Evalue=6e-30,
Organism=Escherichia coli, GI1789809, Length=237, Percent_Identity=31.6455696202532, Blast_Score=110, Evalue=7e-26,
Organism=Escherichia coli, GI1786599, Length=221, Percent_Identity=33.9366515837104, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI2367329, Length=228, Percent_Identity=34.2105263157895, Blast_Score=97, Evalue=6e-22,
Organism=Escherichia coli, GI1790860, Length=221, Percent_Identity=33.9366515837104, Blast_Score=96, Evalue=1e-21,
Organism=Escherichia coli, GI1788394, Length=229, Percent_Identity=29.6943231441048, Blast_Score=92, Evalue=2e-20,
Organism=Escherichia coli, GI1786911, Length=219, Percent_Identity=29.2237442922374, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1787229, Length=232, Percent_Identity=31.0344827586207, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1788550, Length=107, Percent_Identity=39.2523364485981, Blast_Score=81, Evalue=6e-17,
Organism=Escherichia coli, GI1790863, Length=226, Percent_Identity=26.1061946902655, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI145693140, Length=235, Percent_Identity=28.5106382978723, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI1790299, Length=124, Percent_Identity=33.0645161290323, Blast_Score=65, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6322000, Length=116, Percent_Identity=28.448275862069, Blast_Score=65, Evalue=9e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25274; Mature: 25274

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILLVEDEGELAAWLARALAQSGFVVERAADGLAAEAFLASGEFDAVVLDLRLPRKDGF
CEEEEEECCCHHHHHHHHHHHHCCEEEEHHCCCHHHHHHHCCCCCCEEEEEEECCCCCCC
AVLADMRARDDRTPVLILTAQGALDERVRGLNAGADDFLTKPFALTELEARLMALIRRSR
EEEEECCCCCCCCCEEEEECCCCHHHHHHCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHC
GRAFPRLRCGPLEFDTGRKAFLLAGEPLSLTPREHAALSALLHKTGQPISKVHLFDKVFN
CCCCCCCCCCCCEECCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHC
LDSDSSPDAVEVVVHRLRKKLAGSGVQIVTVRGLGYLLEAEASGVPQAAGDTSAP
CCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCEEEECCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRILLVEDEGELAAWLARALAQSGFVVERAADGLAAEAFLASGEFDAVVLDLRLPRKDGF
CEEEEEECCCHHHHHHHHHHHHCCEEEEHHCCCHHHHHHHCCCCCCEEEEEEECCCCCCC
AVLADMRARDDRTPVLILTAQGALDERVRGLNAGADDFLTKPFALTELEARLMALIRRSR
EEEEECCCCCCCCCEEEEECCCCHHHHHHCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHC
GRAFPRLRCGPLEFDTGRKAFLLAGEPLSLTPREHAALSALLHKTGQPISKVHLFDKVFN
CCCCCCCCCCCCEECCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHC
LDSDSSPDAVEVVVHRLRKKLAGSGVQIVTVRGLGYLLEAEASGVPQAAGDTSAP
CCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCEEEECCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2666399; 11083839; 11677609 [H]