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The map label for this gene is degP [H]

Identifier: 17547651

GI number: 17547651

Start: 3161952

End: 3163163

Strand: Direct

Name: degP [H]

Synonym: RSc2932

Alternate gene names: 17547651

Gene position: 3161952-3163163 (Clockwise)

Preceding gene: 17547649

Following gene: 17547654

Centisome position: 85.08

GC content: 64.52

Gene sequence:

>1212_bases
ATGTTGCGCCGCTTCTGGCTGTTTTTCGCACAGGCTGTGACTGTCGTTCTCGCGGTATGGTTTGTGATCGCCACCCTCAA
ACCCGAGTGGTTGCAGCGCGGCAAGGTGGCTGTGCAATCCGGCTCGCCCATCGTCGCGCTCAAGGAAGTCGCGCCACTGG
GCCATAGCGGCACCACCAGCAATTCCTACGCGGAAGCCGCCAAGGTGGCGATGCCCGCGGTGGTCAACATCTTCAGCAGC
AAGAACGCCCCCAAGCGCAACAACCCGCAGGCCAATGCGGACCCGTGGTTCCGCTTCTTCTTCGGGGACCGCCTGCCCGA
GCAGCGCCAGGAACCGACGGCCAGCCTGGGCTCCGGCGTCATCGTCAGCCCGGAAGGCTACATTCTAACGAACCATCATG
TAGTGGACGGCGCCGACGAGATCGAAGTCGCGCTGACAGACGGCCGCAAGGCCAATGCCAAAGTGGTCGGCACGGATCCG
GAAACCGACCTCGCCGTGCTCAAGATCAGCCTGACCAATCTCCCCGCCATCACGCTCGGGCGCCTGGAGAACGTACGCGT
CGGCGATGTGGTGCTGGCCATCGGCAACCCGTTCGGCGTCGGCCAGACCGTGACGATGGGGATCGTGTCGGCGCTGGGCC
GCAGCCACCTCGGCATCAACACCTTCGAGAACTTCATCCAGACCGACGCAGCCATCAACCCCGGCAACTCGGGCGGTGCC
CTGGTCGACGCCGAAGGCAACCTGCTCGGCATTAACACGGCCATCTACTCGCGCTCGGGAGGATCGCTCGGCATCGGCTT
CGCAATTCCCGTGTCGCTGGCCAAGCAGGTGATGGAATCGATCATCTCGACCGGCAGCGTGGTGCGCGGCTGGATCGGCG
TCGAGCCGCAGGACGTGACACCGGAGATCGCCGAATCGTTTGGCCTGTCGCGCAAGGATGGTGCCCTGATTGCCGCGGTC
GTCCAGGGTGGCCCCGCCGATCGAGCCGGCCTGCGCCCGGGCGACATCCTCATCAACGTCAACGGCGAATCGATCCAGGA
CACCACGGCCTTGCTGAACAGCATTGCCCAGCTCAAGCCAAGCACGGAAGCCAAGGTGACCGTGTCACGCAAAGGCAAGC
CCGTTGAACTGACCATCATGGTCGGGAAACGCCCGCCTCCGGTCCGTCGCAATGTGCCGATGCCCTCGCCCGAAGACGAG
CAGCCGCAGTAG

Upstream 100 bases:

>100_bases
CAGGCCATTGGGGCAATAGTCCCGAAAGCGGGCCGCCTGCAACAGGTCGTTCAAGTACAATTCAAGTTCTTTTCGATCCA
TTTCGACTGAAATTCACCCT

Downstream 100 bases:

>100_bases
GCGCCCCTGATCCTCAACGCAGAAAAATGGCGGCTGACATGCCGCCATTTTCTTTGCGTGTGTACTGGGCAAGCAGCAAG
TGGCCCCACCCGCTCCTCCC

Product: HTRA-like serine protease signal peptide protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 403; Mature: 403

Protein sequence:

>403_residues
MLRRFWLFFAQAVTVVLAVWFVIATLKPEWLQRGKVAVQSGSPIVALKEVAPLGHSGTTSNSYAEAAKVAMPAVVNIFSS
KNAPKRNNPQANADPWFRFFFGDRLPEQRQEPTASLGSGVIVSPEGYILTNHHVVDGADEIEVALTDGRKANAKVVGTDP
ETDLAVLKISLTNLPAITLGRLENVRVGDVVLAIGNPFGVGQTVTMGIVSALGRSHLGINTFENFIQTDAAINPGNSGGA
LVDAEGNLLGINTAIYSRSGGSLGIGFAIPVSLAKQVMESIISTGSVVRGWIGVEPQDVTPEIAESFGLSRKDGALIAAV
VQGGPADRAGLRPGDILINVNGESIQDTTALLNSIAQLKPSTEAKVTVSRKGKPVELTIMVGKRPPPVRRNVPMPSPEDE
QPQ

Sequences:

>Translated_403_residues
MLRRFWLFFAQAVTVVLAVWFVIATLKPEWLQRGKVAVQSGSPIVALKEVAPLGHSGTTSNSYAEAAKVAMPAVVNIFSS
KNAPKRNNPQANADPWFRFFFGDRLPEQRQEPTASLGSGVIVSPEGYILTNHHVVDGADEIEVALTDGRKANAKVVGTDP
ETDLAVLKISLTNLPAITLGRLENVRVGDVVLAIGNPFGVGQTVTMGIVSALGRSHLGINTFENFIQTDAAINPGNSGGA
LVDAEGNLLGINTAIYSRSGGSLGIGFAIPVSLAKQVMESIISTGSVVRGWIGVEPQDVTPEIAESFGLSRKDGALIAAV
VQGGPADRAGLRPGDILINVNGESIQDTTALLNSIAQLKPSTEAKVTVSRKGKPVELTIMVGKRPPPVRRNVPMPSPEDE
QPQ
>Mature_403_residues
MLRRFWLFFAQAVTVVLAVWFVIATLKPEWLQRGKVAVQSGSPIVALKEVAPLGHSGTTSNSYAEAAKVAMPAVVNIFSS
KNAPKRNNPQANADPWFRFFFGDRLPEQRQEPTASLGSGVIVSPEGYILTNHHVVDGADEIEVALTDGRKANAKVVGTDP
ETDLAVLKISLTNLPAITLGRLENVRVGDVVLAIGNPFGVGQTVTMGIVSALGRSHLGINTFENFIQTDAAINPGNSGGA
LVDAEGNLLGINTAIYSRSGGSLGIGFAIPVSLAKQVMESIISTGSVVRGWIGVEPQDVTPEIAESFGLSRKDGALIAAV
VQGGPADRAGLRPGDILINVNGESIQDTTALLNSIAQLKPSTEAKVTVSRKGKPVELTIMVGKRPPPVRRNVPMPSPEDE
QPQ

Specific function: Protease With A Shared Specificity With Degp. [C]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI24308541, Length=275, Percent_Identity=35.2727272727273, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI4506141, Length=257, Percent_Identity=36.9649805447471, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI22129776, Length=347, Percent_Identity=31.700288184438, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI7019477, Length=296, Percent_Identity=35.8108108108108, Blast_Score=137, Evalue=2e-32,
Organism=Escherichia coli, GI1789629, Length=323, Percent_Identity=42.4148606811146, Blast_Score=260, Evalue=1e-70,
Organism=Escherichia coli, GI1786356, Length=348, Percent_Identity=40.5172413793103, Blast_Score=232, Evalue=3e-62,
Organism=Escherichia coli, GI1789630, Length=331, Percent_Identity=39.8791540785499, Blast_Score=218, Evalue=4e-58,
Organism=Drosophila melanogaster, GI24646839, Length=304, Percent_Identity=33.5526315789474, Blast_Score=148, Evalue=5e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 42541; Mature: 42541

Theoretical pI: Translated: 6.98; Mature: 6.98

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRRFWLFFAQAVTVVLAVWFVIATLKPEWLQRGKVAVQSGSPIVALKEVAPLGHSGTTS
CCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCEEEECCCCEEEEECCCCCCCCCCCC
NSYAEAAKVAMPAVVNIFSSKNAPKRNNPQANADPWFRFFFGDRLPEQRQEPTASLGSGV
CHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCCHHHCCCCHHHCCCE
IVSPEGYILTNHHVVDGADEIEVALTDGRKANAKVVGTDPETDLAVLKISLTNLPAITLG
EECCCCEEEECCEEECCCCCEEEEEECCCCCCCEEECCCCCCCEEEEEEEECCCCEEEEC
RLENVRVGDVVLAIGNPFGVGQTVTMGIVSALGRSHLGINTFENFIQTDAAINPGNSGGA
CCCCCEECEEEEEECCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCE
LVDAEGNLLGINTAIYSRSGGSLGIGFAIPVSLAKQVMESIISTGSVVRGWIGVEPQDVT
EEECCCCEEEEEEEEEECCCCCEEEHHHHHHHHHHHHHHHHHCCCCCEEHEECCCCCCCC
PEIAESFGLSRKDGALIAAVVQGGPADRAGLRPGDILINVNGESIQDTTALLNSIAQLKP
HHHHHHCCCCCCCCCEEEEEECCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCC
STEAKVTVSRKGKPVELTIMVGKRPPPVRRNVPMPSPEDEQPQ
CCCEEEEEECCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLRRFWLFFAQAVTVVLAVWFVIATLKPEWLQRGKVAVQSGSPIVALKEVAPLGHSGTTS
CCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCEEEECCCCEEEEECCCCCCCCCCCC
NSYAEAAKVAMPAVVNIFSSKNAPKRNNPQANADPWFRFFFGDRLPEQRQEPTASLGSGV
CHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCCHHHCCCCHHHCCCE
IVSPEGYILTNHHVVDGADEIEVALTDGRKANAKVVGTDPETDLAVLKISLTNLPAITLG
EECCCCEEEECCEEECCCCCEEEEEECCCCCCCEEECCCCCCCEEEEEEEECCCCEEEEC
RLENVRVGDVVLAIGNPFGVGQTVTMGIVSALGRSHLGINTFENFIQTDAAINPGNSGGA
CCCCCEECEEEEEECCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCE
LVDAEGNLLGINTAIYSRSGGSLGIGFAIPVSLAKQVMESIISTGSVVRGWIGVEPQDVT
EEECCCCEEEEEEEEEECCCCCEEEHHHHHHHHHHHHHHHHHCCCCCEEHEECCCCCCCC
PEIAESFGLSRKDGALIAAVVQGGPADRAGLRPGDILINVNGESIQDTTALLNSIAQLKP
HHHHHHCCCCCCCCCEEEEEECCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCC
STEAKVTVSRKGKPVELTIMVGKRPPPVRRNVPMPSPEDEQPQ
CCCEEEEEECCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10684935 [H]