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The map label for this gene is pehR [H]

Identifier: 17547526

GI number: 17547526

Start: 3019472

End: 3021184

Strand: Reverse

Name: pehR [H]

Synonym: RSc2807

Alternate gene names: 17547526

Gene position: 3021184-3019472 (Counterclockwise)

Preceding gene: 17547527

Following gene: 17547525

Centisome position: 81.29

GC content: 71.98

Gene sequence:

>1713_bases
ATGAGCCGCCAGCCGTTTTTCCGTCCCCCCATGTCCAAAGCTGCCGTCGTTCGCGAACCCATCCTCGTCGTCGATGACGA
GGCCGATCTGCGTGAGCTGCTGGAGATCTCCCTGCGGCGCATGGGGCACGATGTGGTGCTGGCCGGCGGCCTGGCCGAGG
CGCGCGAGGCGCTGACGCGGCAACGCTTTGCGCTGGTGCTGACCGACATGCGCCTGGGCGACGGCCTGGGCATCGACCTG
GTGCGCCAGCTCTCGGCCACCGCCGATCGCACGCCGGTGGCCGTCATCACCGCCTACGGCAGCGCCGAGAACGCGGTGGA
GGCGCTCAAGGCGGGCGCGTTCGACTACATCGCCAAGCCGCTGTCGCTCGACCAGCTGCGCAGCCTGGTGCTCAACGCGC
TGGGCCGCCAGCAGCGCGATCCCGATCCCGGCAGCGCCGATCTCGCCGAACGCACCAGTGCGCTGCTGCCCGGCCATTCG
GCCGCCATGCAGGAGGTGCGCCGCTCGCTGCTGCGGCTGGCGCGCAGCATGGCGCCGGTGGTGATCAGCGGCGAATCGGG
CAGCGGCAAGGAGCGCGCGGCGCGCGCCATCCACGCGCTGTCGTCGCGCTCGGCGCGGCCGTTCGTGGCCGTCAACTGCG
GCGCGATTCCCGAGAACCTGATGGAAGCCGAGTTCTTCGGCTACGTGAAGGGTGCCTTCACGGGTGCCGACAGCGACCGC
CAGGGCTTCTTCCAGGCGGCCCACGGCGGCACGCTCATGCTCGACGAGGTGGCCGACCTGCCGCTGACCATGCAGGTCAA
GCTGCTGCGCGCGCTGCAGGAGCGCCGCGTGCGCAAGATCGGCGAGAGCCGCGAAGACCCGGTCGACGTGCGCGTGGTAT
GCGCGAGCCACCAGAACCTCGCGCGCCTGGTCGCCGCCGGGCGTTTCCGCGAAGATTTGTTCTACCGGCTCAACGTGCTG
GAGCTGCGCATGCCGACGCTGCGCGAGCGCGCCGAGGACGTGCCGGTCCTGGCGGGCGTGCTGCTGGAGCAGCTGGCCGC
GCGCTATGGCGATCTGCGGCCGAAGCGGCTTACGCGCCAGGCGCTACAGCAGCTGTGCGCCTATCCGTTCCCCGGCAACG
TGCGCGAGCTGGATAACCTGCTGGAGCGCGCCTACGCCTTTGCCGAGGGCGAGTCGATCGACGTGGACCATCTCGGCGCG
CTGGGCACCGACATCGAGCGCTCGCCGCTGTTCCATCGCGCGCGCGAGGCGCATGGCGGCCATCCCGTGCACCCGGCGCA
CCTGCCGCCGGTGCCGGCGCCCGGCCATCCCGCCCATCCGGGGCATCCCGGCCATGTCGCGCATCCGCTCGGCGTGCCGC
AGCCGGTGGGCGGCTGGCCCGATGCGGCCTACATTCCCGTGCCGGTGCCGATGGGCCTGATGCCGCATCCCGTCGTCGTG
CCCGTGCCGGTCGAGCCCGCGCCGGTGATCGAGCCGGCCGCGCCGGCCATGCCCGCGGTGTCCTTGCCGGTGGACTTGCC
GGCCTACCTCGAATCGGTGGAGCGCGGCGTGATCCTGGCCGCGCTGGCGCAGACCGGCTTCAACCGGACGGCGGCCTCCA
AGCTGCTCGGCCTGAGCTTCCGGCAGCTGCGCTACCGGATGCAGCAGCTGGACATCCGCGATCCGCGCGACATCGAAGCC
GCGGCGGGCAACGGCGGGGTGGGTGATGCCTGA

Upstream 100 bases:

>100_bases
TCGATCGCACCGGAGTGATGACCATGGAGGTGCGCGAGGGCCTGCCGCGCCGCGCTTTCGTCATCACCCTGATGTTCGAC
CCACCCGCTGTGCCGGCGGA

Downstream 100 bases:

>100_bases
GGTGGCCGGGCCGGTGCGCATCGGCGCGGACGGCTGGGCGGACGGGGTGTGCCGGCATCCTTCGCCCAATGTCGATGCGC
GCCCCGAGGGCCTGCCGATC

Product: response regulator transcription regulator protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 570; Mature: 569

Protein sequence:

>570_residues
MSRQPFFRPPMSKAAVVREPILVVDDEADLRELLEISLRRMGHDVVLAGGLAEAREALTRQRFALVLTDMRLGDGLGIDL
VRQLSATADRTPVAVITAYGSAENAVEALKAGAFDYIAKPLSLDQLRSLVLNALGRQQRDPDPGSADLAERTSALLPGHS
AAMQEVRRSLLRLARSMAPVVISGESGSGKERAARAIHALSSRSARPFVAVNCGAIPENLMEAEFFGYVKGAFTGADSDR
QGFFQAAHGGTLMLDEVADLPLTMQVKLLRALQERRVRKIGESREDPVDVRVVCASHQNLARLVAAGRFREDLFYRLNVL
ELRMPTLRERAEDVPVLAGVLLEQLAARYGDLRPKRLTRQALQQLCAYPFPGNVRELDNLLERAYAFAEGESIDVDHLGA
LGTDIERSPLFHRAREAHGGHPVHPAHLPPVPAPGHPAHPGHPGHVAHPLGVPQPVGGWPDAAYIPVPVPMGLMPHPVVV
PVPVEPAPVIEPAAPAMPAVSLPVDLPAYLESVERGVILAALAQTGFNRTAASKLLGLSFRQLRYRMQQLDIRDPRDIEA
AAGNGGVGDA

Sequences:

>Translated_570_residues
MSRQPFFRPPMSKAAVVREPILVVDDEADLRELLEISLRRMGHDVVLAGGLAEAREALTRQRFALVLTDMRLGDGLGIDL
VRQLSATADRTPVAVITAYGSAENAVEALKAGAFDYIAKPLSLDQLRSLVLNALGRQQRDPDPGSADLAERTSALLPGHS
AAMQEVRRSLLRLARSMAPVVISGESGSGKERAARAIHALSSRSARPFVAVNCGAIPENLMEAEFFGYVKGAFTGADSDR
QGFFQAAHGGTLMLDEVADLPLTMQVKLLRALQERRVRKIGESREDPVDVRVVCASHQNLARLVAAGRFREDLFYRLNVL
ELRMPTLRERAEDVPVLAGVLLEQLAARYGDLRPKRLTRQALQQLCAYPFPGNVRELDNLLERAYAFAEGESIDVDHLGA
LGTDIERSPLFHRAREAHGGHPVHPAHLPPVPAPGHPAHPGHPGHVAHPLGVPQPVGGWPDAAYIPVPVPMGLMPHPVVV
PVPVEPAPVIEPAAPAMPAVSLPVDLPAYLESVERGVILAALAQTGFNRTAASKLLGLSFRQLRYRMQQLDIRDPRDIEA
AAGNGGVGDA
>Mature_569_residues
SRQPFFRPPMSKAAVVREPILVVDDEADLRELLEISLRRMGHDVVLAGGLAEAREALTRQRFALVLTDMRLGDGLGIDLV
RQLSATADRTPVAVITAYGSAENAVEALKAGAFDYIAKPLSLDQLRSLVLNALGRQQRDPDPGSADLAERTSALLPGHSA
AMQEVRRSLLRLARSMAPVVISGESGSGKERAARAIHALSSRSARPFVAVNCGAIPENLMEAEFFGYVKGAFTGADSDRQ
GFFQAAHGGTLMLDEVADLPLTMQVKLLRALQERRVRKIGESREDPVDVRVVCASHQNLARLVAAGRFREDLFYRLNVLE
LRMPTLRERAEDVPVLAGVLLEQLAARYGDLRPKRLTRQALQQLCAYPFPGNVRELDNLLERAYAFAEGESIDVDHLGAL
GTDIERSPLFHRAREAHGGHPVHPAHLPPVPAPGHPAHPGHPGHVAHPLGVPQPVGGWPDAAYIPVPVPMGLMPHPVVVP
VPVEPAPVIEPAAPAMPAVSLPVDLPAYLESVERGVILAALAQTGFNRTAASKLLGLSFRQLRYRMQQLDIRDPRDIEAA
AGNGGVGDA

Specific function: Member of the two-component regulatory system pilS/pilR that regulates the expression of type 4 fimbriae. When activated by pilS it acts in conjunction with sigma-54 as a transcriptional activator [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=373, Percent_Identity=46.112600536193, Blast_Score=308, Evalue=5e-85,
Organism=Escherichia coli, GI1788550, Length=378, Percent_Identity=42.3280423280423, Blast_Score=288, Evalue=5e-79,
Organism=Escherichia coli, GI1788905, Length=368, Percent_Identity=41.5760869565217, Blast_Score=276, Evalue=2e-75,
Organism=Escherichia coli, GI1790299, Length=381, Percent_Identity=40.9448818897638, Blast_Score=268, Evalue=5e-73,
Organism=Escherichia coli, GI87082117, Length=349, Percent_Identity=39.8280802292264, Blast_Score=226, Evalue=2e-60,
Organism=Escherichia coli, GI1789233, Length=241, Percent_Identity=48.1327800829876, Blast_Score=226, Evalue=3e-60,
Organism=Escherichia coli, GI1786524, Length=244, Percent_Identity=48.7704918032787, Blast_Score=211, Evalue=9e-56,
Organism=Escherichia coli, GI87082152, Length=231, Percent_Identity=48.0519480519481, Blast_Score=201, Evalue=8e-53,
Organism=Escherichia coli, GI1789087, Length=238, Percent_Identity=43.2773109243698, Blast_Score=198, Evalue=7e-52,
Organism=Escherichia coli, GI1787583, Length=231, Percent_Identity=41.5584415584416, Blast_Score=178, Evalue=8e-46,
Organism=Escherichia coli, GI87081872, Length=237, Percent_Identity=40.5063291139241, Blast_Score=165, Evalue=6e-42,
Organism=Escherichia coli, GI1789828, Length=231, Percent_Identity=35.4978354978355, Blast_Score=132, Evalue=7e-32,
Organism=Escherichia coli, GI87081858, Length=209, Percent_Identity=33.9712918660287, Blast_Score=118, Evalue=1e-27,
Organism=Escherichia coli, GI1789809, Length=117, Percent_Identity=34.1880341880342, Blast_Score=64, Evalue=4e-11,
Organism=Escherichia coli, GI1786838, Length=108, Percent_Identity=35.1851851851852, Blast_Score=63, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 61595; Mature: 61463

Theoretical pI: Translated: 7.00; Mature: 7.00

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRQPFFRPPMSKAAVVREPILVVDDEADLRELLEISLRRMGHDVVLAGGLAEAREALTR
CCCCCCCCCCCHHHHHHHCCEEEECCCHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHH
QRFALVLTDMRLGDGLGIDLVRQLSATADRTPVAVITAYGSAENAVEALKAGAFDYIAKP
HHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHCCHHHHHCC
LSLDQLRSLVLNALGRQQRDPDPGSADLAERTSALLPGHSAAMQEVRRSLLRLARSMAPV
CCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCE
VISGESGSGKERAARAIHALSSRSARPFVAVNCGAIPENLMEAEFFGYVKGAFTGADSDR
EEECCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCH
QGFFQAAHGGTLMLDEVADLPLTMQVKLLRALQERRVRKIGESREDPVDVRVVCASHQNL
HHHHHHCCCCEEEEHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCHHH
ARLVAAGRFREDLFYRLNVLELRMPTLRERAEDVPVLAGVLLEQLAARYGDLRPKRLTRQ
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHH
ALQQLCAYPFPGNVRELDNLLERAYAFAEGESIDVDHLGALGTDIERSPLFHRAREAHGG
HHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCHHHHHHHHHCCC
HPVHPAHLPPVPAPGHPAHPGHPGHVAHPLGVPQPVGGWPDAAYIPVPVPMGLMPHPVVV
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCEEE
PVPVEPAPVIEPAAPAMPAVSLPVDLPAYLESVERGVILAALAQTGFNRTAASKLLGLSF
ECCCCCCCCCCCCCCCCCCEECCCCCHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHH
RQLRYRMQQLDIRDPRDIEAAAGNGGVGDA
HHHHHHHHHCCCCCCCCCHHCCCCCCCCCC
>Mature Secondary Structure 
SRQPFFRPPMSKAAVVREPILVVDDEADLRELLEISLRRMGHDVVLAGGLAEAREALTR
CCCCCCCCCCHHHHHHHCCEEEECCCHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHH
QRFALVLTDMRLGDGLGIDLVRQLSATADRTPVAVITAYGSAENAVEALKAGAFDYIAKP
HHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHCCHHHHHCC
LSLDQLRSLVLNALGRQQRDPDPGSADLAERTSALLPGHSAAMQEVRRSLLRLARSMAPV
CCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCE
VISGESGSGKERAARAIHALSSRSARPFVAVNCGAIPENLMEAEFFGYVKGAFTGADSDR
EEECCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCH
QGFFQAAHGGTLMLDEVADLPLTMQVKLLRALQERRVRKIGESREDPVDVRVVCASHQNL
HHHHHHCCCCEEEEHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCHHH
ARLVAAGRFREDLFYRLNVLELRMPTLRERAEDVPVLAGVLLEQLAARYGDLRPKRLTRQ
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHH
ALQQLCAYPFPGNVRELDNLLERAYAFAEGESIDVDHLGALGTDIERSPLFHRAREAHGG
HHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCHHHHHHHHHCCC
HPVHPAHLPPVPAPGHPAHPGHPGHVAHPLGVPQPVGGWPDAAYIPVPVPMGLMPHPVVV
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCEEE
PVPVEPAPVIEPAAPAMPAVSLPVDLPAYLESVERGVILAALAQTGFNRTAASKLLGLSF
ECCCCCCCCCCCCCCCCCCEECCCCCHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHH
RQLRYRMQQLDIRDPRDIEAAAGNGGVGDA
HHHHHHHHHCCCCCCCCCHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1317379; 8097014; 7911557; 10984043 [H]