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The map label for this gene is kdsB [H]

Identifier: 17547251

GI number: 17547251

Start: 2739468

End: 2740274

Strand: Direct

Name: kdsB [H]

Synonym: RSc2532

Alternate gene names: 17547251

Gene position: 2739468-2740274 (Clockwise)

Preceding gene: 17547250

Following gene: 17547252

Centisome position: 73.71

GC content: 72.49

Gene sequence:

>807_bases
ATGTCGCACGCGCCGTTCATTGCCGTCATCCCCGCGCGGCTCGCCTCCACGCGGCTGCCCAACAAGCCGCTGGCCGACAT
CGGCGGCAAGCCGATGGTGGTGCGCGTGGCCGAACGCGCGCACCAGTCGTCGGCGGCGCGCGTGGTGGTCGCCACCGATG
CCGTCTCGGTGGCCGATGCCTGCATGCAGCACCATATCGAGGCGGTGCTGACCCGTGCCGACCACGCGTCGGGCACGGAC
CGGCTGGCGGAGGTCGCCACCGTGCTGGCGCTGCCCGATGACGCCATCGTCGTCAACGTGCAGGGCGACGAACCGCTGAT
CGCCCCGACGCTGATCGACAACGTGGCCGCGCACCTGCGCGACCACGCCGATTGCGCCATCGCCACCGCCGCCCATCCCA
TCCGCGCCGCCGCCGACATCTTCAACCCGAACGTGGTCAAGGTCGTGCTGGACGCCGCCGAGCGCGCGCTGCTGTTCTCG
CGCGCCCCGCTGCCCTGGGCGCGCGATGCCTGGACGCCCGCCGCGCTGGACCAGCCCGCCGCCGAACGCCCGCTGCCCGC
CATGCCGGTGCTGCGCCATATCGGCATCTACGCCTACCGTGCCGCCTTCCTGCGACGCTTCCCGCAGCTGGCCGCCGCGC
CGCTGGAGCAGACCGAGCAGCTCGAGCAACTGCGCGCCATGTGGCACGGCGAACGCATCGCCGTGCTGACCACCGACGAT
GCACCGGCCGCCGGCGTCGATACGGCGGAAGACCTCGCCCGCGTGCGCGCGGCATGGAGCGATTTATTGTCGCAGGACGG
GCCCTAG

Upstream 100 bases:

>100_bases
TCCGATCCGCGATGGCATCCCCGTGATGCTGGCCGACGAGGCGCGCCAGACCGTCGAAGGCACGCCGGTCGATCCGGCCT
GACGCGGACGACGCCCCGCC

Downstream 100 bases:

>100_bases
CGGGAACTTTGCCCCGCCGCGCGGCAATCCCCCCGCGCCGCCATGGCATAATCGCGAGGATGACAAGTCGCATGCCGCCG
CCCACGACAGGCGCGGCAGC

Product: 3-deoxy-manno-octulosonate cytidylyltransferase

Products: NA

Alternate protein names: CMP-2-keto-3-deoxyoctulosonic acid synthase; CKS; CMP-KDO synthase [H]

Number of amino acids: Translated: 268; Mature: 267

Protein sequence:

>268_residues
MSHAPFIAVIPARLASTRLPNKPLADIGGKPMVVRVAERAHQSSAARVVVATDAVSVADACMQHHIEAVLTRADHASGTD
RLAEVATVLALPDDAIVVNVQGDEPLIAPTLIDNVAAHLRDHADCAIATAAHPIRAAADIFNPNVVKVVLDAAERALLFS
RAPLPWARDAWTPAALDQPAAERPLPAMPVLRHIGIYAYRAAFLRRFPQLAAAPLEQTEQLEQLRAMWHGERIAVLTTDD
APAAGVDTAEDLARVRAAWSDLLSQDGP

Sequences:

>Translated_268_residues
MSHAPFIAVIPARLASTRLPNKPLADIGGKPMVVRVAERAHQSSAARVVVATDAVSVADACMQHHIEAVLTRADHASGTD
RLAEVATVLALPDDAIVVNVQGDEPLIAPTLIDNVAAHLRDHADCAIATAAHPIRAAADIFNPNVVKVVLDAAERALLFS
RAPLPWARDAWTPAALDQPAAERPLPAMPVLRHIGIYAYRAAFLRRFPQLAAAPLEQTEQLEQLRAMWHGERIAVLTTDD
APAAGVDTAEDLARVRAAWSDLLSQDGP
>Mature_267_residues
SHAPFIAVIPARLASTRLPNKPLADIGGKPMVVRVAERAHQSSAARVVVATDAVSVADACMQHHIEAVLTRADHASGTDR
LAEVATVLALPDDAIVVNVQGDEPLIAPTLIDNVAAHLRDHADCAIATAAHPIRAAADIFNPNVVKVVLDAAERALLFSR
APLPWARDAWTPAALDQPAAERPLPAMPVLRHIGIYAYRAAFLRRFPQLAAAPLEQTEQLEQLRAMWHGERIAVLTTDDA
PAAGVDTAEDLARVRAAWSDLLSQDGP

Specific function: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria [H]

COG id: COG1212

COG function: function code M; CMP-2-keto-3-deoxyoctulosonic acid synthetase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsB family [H]

Homologues:

Organism=Escherichia coli, GI1787147, Length=252, Percent_Identity=52.3809523809524, Blast_Score=244, Evalue=4e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003329
- InterPro:   IPR004528 [H]

Pfam domain/function: PF02348 CTP_transf_3 [H]

EC number: =2.7.7.38 [H]

Molecular weight: Translated: 28621; Mature: 28490

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHAPFIAVIPARLASTRLPNKPLADIGGKPMVVRVAERAHQSSAARVVVATDAVSVADA
CCCCCEEEEHHHHHHHCCCCCCCHHHCCCCCEEEHHHHHHHHHCCCEEEEEECHHHHHHH
CMQHHIEAVLTRADHASGTDRLAEVATVLALPDDAIVVNVQGDEPLIAPTLIDNVAAHLR
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCEEHHHHHHHHHHHHH
DHADCAIATAAHPIRAAADIFNPNVVKVVLDAAERALLFSRAPLPWARDAWTPAALDQPA
HCCCHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHCCCCC
AERPLPAMPVLRHIGIYAYRAAFLRRFPQLAAAPLEQTEQLEQLRAMWHGERIAVLTTDD
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEEEEECCC
APAAGVDTAEDLARVRAAWSDLLSQDGP
CCCCCCCCHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SHAPFIAVIPARLASTRLPNKPLADIGGKPMVVRVAERAHQSSAARVVVATDAVSVADA
CCCCEEEEHHHHHHHCCCCCCCHHHCCCCCEEEHHHHHHHHHCCCEEEEEECHHHHHHH
CMQHHIEAVLTRADHASGTDRLAEVATVLALPDDAIVVNVQGDEPLIAPTLIDNVAAHLR
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCEEHHHHHHHHHHHHH
DHADCAIATAAHPIRAAADIFNPNVVKVVLDAAERALLFSRAPLPWARDAWTPAALDQPA
HCCCHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHCCCCC
AERPLPAMPVLRHIGIYAYRAAFLRRFPQLAAAPLEQTEQLEQLRAMWHGERIAVLTTDD
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEEEEECCC
APAAGVDTAEDLARVRAAWSDLLSQDGP
CCCCCCCCHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA