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The map label for this gene is yhcS [C]

Identifier: 17547217

GI number: 17547217

Start: 2704180

End: 2705106

Strand: Reverse

Name: yhcS [C]

Synonym: RSc2498

Alternate gene names: 17547217

Gene position: 2705106-2704180 (Counterclockwise)

Preceding gene: 17547219

Following gene: 17547216

Centisome position: 72.79

GC content: 73.46

Gene sequence:

>927_bases
ATGCGAACAATGGAGTGGAACGACTGGGAGACCTTCTGCCGCGTGGTGGAGGCGGGGAGCTTCACCGCCGCCGCCGAGGC
GCTGGGCATCCCCAAATCCAGCGCCAGCGCCGCCGTCTCGCGGCTGGAGGCGTCGCTGGGCGTGCGCCTGCTCACGCGCA
CCACGCGCCAACTGCGGCTGACCGAAGCCGGCTCGCACTTCTACGACGACATCGCGCCGCTGTTCGAGCGCCTGCGCGAA
GTCCACGCTGACACGACCGCCGCCAGCGAGACCGTCTCCGGCACGCTGCGCATCGCCGCGCCGTACGAGGTCGGCGCGCA
GCACCTGACCGAGCCGGTCTGCCAGACGCTGGCGCGCTTCCCCAACCTGCAGATCCAGGTGCACATCTCGTGGGAGCAGC
CCGACCTGCTCGCCAGCGGCTACGACATCGTGTTCGTGATGGTGGACCAGACCCTGGCCGATTCGTCGCTGGTGGCGCGC
CGCGTGGTGATGATCCCGCGCGCGCTGTATGCGGCGCCGTCCCTGCTGGCCGGGCGCGCGCCGCTCGCCGCACCCGCCGA
CCTGTCCGGCTGGCCGTGCCTGTCCGGCCCGGACGATGCCAGCTGGGTGTTCCGGCCGGCCGGGGCGCCCGCCGCCGAGC
CCTTCGAAGTGCCGATCCAGCCCCGCCTGCAGACGCTCAACGCCGAGATGCGCGCTCGCGCCGCGGTGCGCGGCCTGGGC
GTGGCCCGCATGGCGCGCTCGGTGGGCGACGCGGAAGTCGAGACCGGACGCCTGGTGCGCGTGCTGTCCGACTACGAGCC
GACACCGCTGCGGGTCTACGCGCTGATGCCCGCGCGCAAGCTGGTGCCGCGCAAGGTGCGGGTCTTCCTCGACGCGCTGG
AGGCGCAGGGGACGGCGGCCACGCCGATGCCCGGCGCCCAGGCCTAG

Upstream 100 bases:

>100_bases
CGCATCGACGCGGGCGGCAGGATTTGCAGCGACATGGGAGCCGAGCATAAACTTGGCCGCCCGCCGGATAAACGCTCAAC
TCTGGGAACACTGTCCAGTC

Downstream 100 bases:

>100_bases
GCGAGGGCTTGCACCGGATGCCACAATCAACGTTTCCGGATGGTTGACCGAGGACCGCGCCGCCATGCGCCTGCGCCAGA
TCGAAGTGTTCCGCGCCGTG

Product: transcription regulator protein

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MRTMEWNDWETFCRVVEAGSFTAAAEALGIPKSSASAAVSRLEASLGVRLLTRTTRQLRLTEAGSHFYDDIAPLFERLRE
VHADTTAASETVSGTLRIAAPYEVGAQHLTEPVCQTLARFPNLQIQVHISWEQPDLLASGYDIVFVMVDQTLADSSLVAR
RVVMIPRALYAAPSLLAGRAPLAAPADLSGWPCLSGPDDASWVFRPAGAPAAEPFEVPIQPRLQTLNAEMRARAAVRGLG
VARMARSVGDAEVETGRLVRVLSDYEPTPLRVYALMPARKLVPRKVRVFLDALEAQGTAATPMPGAQA

Sequences:

>Translated_308_residues
MRTMEWNDWETFCRVVEAGSFTAAAEALGIPKSSASAAVSRLEASLGVRLLTRTTRQLRLTEAGSHFYDDIAPLFERLRE
VHADTTAASETVSGTLRIAAPYEVGAQHLTEPVCQTLARFPNLQIQVHISWEQPDLLASGYDIVFVMVDQTLADSSLVAR
RVVMIPRALYAAPSLLAGRAPLAAPADLSGWPCLSGPDDASWVFRPAGAPAAEPFEVPIQPRLQTLNAEMRARAAVRGLG
VARMARSVGDAEVETGRLVRVLSDYEPTPLRVYALMPARKLVPRKVRVFLDALEAQGTAATPMPGAQA
>Mature_308_residues
MRTMEWNDWETFCRVVEAGSFTAAAEALGIPKSSASAAVSRLEASLGVRLLTRTTRQLRLTEAGSHFYDDIAPLFERLRE
VHADTTAASETVSGTLRIAAPYEVGAQHLTEPVCQTLARFPNLQIQVHISWEQPDLLASGYDIVFVMVDQTLADSSLVAR
RVVMIPRALYAAPSLLAGRAPLAAPADLSGWPCLSGPDDASWVFRPAGAPAAEPFEVPIQPRLQTLNAEMRARAAVRGLG
VARMARSVGDAEVETGRLVRVLSDYEPTPLRVYALMPARKLVPRKVRVFLDALEAQGTAATPMPGAQA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789639, Length=285, Percent_Identity=34.0350877192982, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1786401, Length=284, Percent_Identity=29.9295774647887, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI87081978, Length=294, Percent_Identity=25.8503401360544, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI145693193, Length=294, Percent_Identity=26.8707482993197, Blast_Score=91, Evalue=8e-20,
Organism=Escherichia coli, GI1787128, Length=304, Percent_Identity=25.3289473684211, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI1787589, Length=307, Percent_Identity=25.7328990228013, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1789440, Length=306, Percent_Identity=25.4901960784314, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI1789173, Length=250, Percent_Identity=26.8, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788748, Length=119, Percent_Identity=32.7731092436975, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788481, Length=294, Percent_Identity=23.469387755102, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33313; Mature: 33313

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTMEWNDWETFCRVVEAGSFTAAAEALGIPKSSASAAVSRLEASLGVRLLTRTTRQLRL
CCCCCCCCHHHHHHHHHCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEE
TEAGSHFYDDIAPLFERLREVHADTTAASETVSGTLRIAAPYEVGAQHLTEPVCQTLARF
ECCCCHHHHHHHHHHHHHHHHHCCHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHC
PNLQIQVHISWEQPDLLASGYDIVFVMVDQTLADSSLVARRVVMIPRALYAAPSLLAGRA
CCCEEEEEEECCCCCHHHCCCCEEEEEECCHHCHHHHHHHHHHHHHHHHHHCCHHHCCCC
PLAAPADLSGWPCLSGPDDASWVFRPAGAPAAEPFEVPIQPRLQTLNAEMRARAAVRGLG
CCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
VARMARSVGDAEVETGRLVRVLSDYEPTPLRVYALMPARKLVPRKVRVFLDALEAQGTAA
HHHHHHHCCCCCCCHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHCCCCCC
TPMPGAQA
CCCCCCCC
>Mature Secondary Structure
MRTMEWNDWETFCRVVEAGSFTAAAEALGIPKSSASAAVSRLEASLGVRLLTRTTRQLRL
CCCCCCCCHHHHHHHHHCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEE
TEAGSHFYDDIAPLFERLREVHADTTAASETVSGTLRIAAPYEVGAQHLTEPVCQTLARF
ECCCCHHHHHHHHHHHHHHHHHCCHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHC
PNLQIQVHISWEQPDLLASGYDIVFVMVDQTLADSSLVARRVVMIPRALYAAPSLLAGRA
CCCEEEEEEECCCCCHHHCCCCEEEEEECCHHCHHHHHHHHHHHHHHHHHHCCHHHCCCC
PLAAPADLSGWPCLSGPDDASWVFRPAGAPAAEPFEVPIQPRLQTLNAEMRARAAVRGLG
CCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
VARMARSVGDAEVETGRLVRVLSDYEPTPLRVYALMPARKLVPRKVRVFLDALEAQGTAA
HHHHHHHCCCCCCCHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHCCCCCC
TPMPGAQA
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8635745; 7542800 [H]