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The map label for this gene is rnz [H]

Identifier: 17547214

GI number: 17547214

Start: 2701655

End: 2702617

Strand: Direct

Name: rnz [H]

Synonym: RSc2495

Alternate gene names: 17547214

Gene position: 2701655-2702617 (Clockwise)

Preceding gene: 17547213

Following gene: 17547218

Centisome position: 72.7

GC content: 69.78

Gene sequence:

>963_bases
ATGCAAGCTTTCGACAACAACCGTCGCCGCTGGATGCGGCAGGCCGGGGCGCTGGCCGCCGGCTCCGTCGCCGCGTCGTC
CGGGGTGTGGCCGCTGACCTCGCGGGCGGCGCAGCCCCAGGGCACGCGCCTGATCCTGCTCGGCACCGGCGGCGGGCCGA
CGCCCAAGAAGAACCGCTCGGCGCCGGCGCAGGTGATCGTCATCAACGGCGTGTCGTACGTGGTGGATTGCGGCAACGGC
GTCGCGCGCCAGTACGTGAGCGCTGGCCTCACGCTCAAGGCGATCCGCCACGTCTTCATCACGCACCAGCATTCCGACCA
CAACGCCGACTACGGCGCGCTGATGCTGCTGGCCTGGGGCACCGACCTGGCCGGCCCCGTCGATGCGTGGGGCCCGCCCC
CGCTGGCCGCGATGACGGCCAGGTTCCTGGAACTGTACGACTACGACATCCGCACCCGCATCGCCGACGAGGGCCGCCCA
CCGCTGGCGCCGATGCTCCATCCGCACGAACTGACCGAAGGCGGCCTGGTGATGCAGGACGCCAACGTGAAGGTGACCAG
CGCGCTGGTCAAGCACCCGCCGGTGTCGCCGGCCTTTGCCTACCGCTTCGATGCGGCGGACCGCTCCATCGTCATCTCGG
GCGATACCGCGCCCAGCGAGAACCTGGTGCGCCTGGCCCACGGCGCCGACGTGCTGGTGCACGAGGTGATGCACCTGCCA
TCGCTGGACAAACTGTTGTCCACCGAGCCGAATGCCAAGACGCTGCGCGAGCACCTGCTGGCAAGCCACACGTCCGCCGA
GGACGTCGGCCGCATCGCGACCGAGGCCAAGGTGAAGACGCTGGTGCTGTCGCACTTCGTGCCGGGCGGCTATCCGTATC
TGGACGATGCGGCGTGGCTCGACGCCGTGCGCCCGCACTTCAAGGGCGAGATCATCGTGGGGCGCGACCTGCTGGAGATC
TGA

Upstream 100 bases:

>100_bases
AAGGGCTGGTTCACCCGCAAGGGGATCAAGGTCGGCACCAAGGTCGGCTCGCTGCCCCGCTGACACGACAACCCATCCGA
CCGGACGAGGAAACCACCGC

Downstream 100 bases:

>100_bases
TCCGATGCGCCGGCGCGGCTAGCGCGCCTCGGCGCAATCGCGATAGACCGTGCTGCGGCTGGCGGGCAGGGTTTCGTCGG
TCAGGAAGCCGGTGGGGCCC

Product: hydrolase

Products: NA

Alternate protein names: RNase Z; tRNA 3 endonuclease; tRNase Z [H]

Number of amino acids: Translated: 320; Mature: 320

Protein sequence:

>320_residues
MQAFDNNRRRWMRQAGALAAGSVAASSGVWPLTSRAAQPQGTRLILLGTGGGPTPKKNRSAPAQVIVINGVSYVVDCGNG
VARQYVSAGLTLKAIRHVFITHQHSDHNADYGALMLLAWGTDLAGPVDAWGPPPLAAMTARFLELYDYDIRTRIADEGRP
PLAPMLHPHELTEGGLVMQDANVKVTSALVKHPPVSPAFAYRFDAADRSIVISGDTAPSENLVRLAHGADVLVHEVMHLP
SLDKLLSTEPNAKTLREHLLASHTSAEDVGRIATEAKVKTLVLSHFVPGGYPYLDDAAWLDAVRPHFKGEIIVGRDLLEI

Sequences:

>Translated_320_residues
MQAFDNNRRRWMRQAGALAAGSVAASSGVWPLTSRAAQPQGTRLILLGTGGGPTPKKNRSAPAQVIVINGVSYVVDCGNG
VARQYVSAGLTLKAIRHVFITHQHSDHNADYGALMLLAWGTDLAGPVDAWGPPPLAAMTARFLELYDYDIRTRIADEGRP
PLAPMLHPHELTEGGLVMQDANVKVTSALVKHPPVSPAFAYRFDAADRSIVISGDTAPSENLVRLAHGADVLVHEVMHLP
SLDKLLSTEPNAKTLREHLLASHTSAEDVGRIATEAKVKTLVLSHFVPGGYPYLDDAAWLDAVRPHFKGEIIVGRDLLEI
>Mature_320_residues
MQAFDNNRRRWMRQAGALAAGSVAASSGVWPLTSRAAQPQGTRLILLGTGGGPTPKKNRSAPAQVIVINGVSYVVDCGNG
VARQYVSAGLTLKAIRHVFITHQHSDHNADYGALMLLAWGTDLAGPVDAWGPPPLAAMTARFLELYDYDIRTRIADEGRP
PLAPMLHPHELTEGGLVMQDANVKVTSALVKHPPVSPAFAYRFDAADRSIVISGDTAPSENLVRLAHGADVLVHEVMHLP
SLDKLLSTEPNAKTLREHLLASHTSAEDVGRIATEAKVKTLVLSHFVPGGYPYLDDAAWLDAVRPHFKGEIIVGRDLLEI

Specific function: Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA [H]

COG id: COG1234

COG function: function code R; Metal-dependent hydrolases of the beta-lactamase superfamily III

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase Z family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279
- InterPro:   IPR013471 [H]

Pfam domain/function: PF00753 Lactamase_B [H]

EC number: =3.1.26.11 [H]

Molecular weight: Translated: 34464; Mature: 34464

Theoretical pI: Translated: 7.26; Mature: 7.26

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQAFDNNRRRWMRQAGALAAGSVAASSGVWPLTSRAAQPQGTRLILLGTGGGPTPKKNRS
CCCCCCHHHHHHHHHCCCCCCCHHCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCC
APAQVIVINGVSYVVDCGNGVARQYVSAGLTLKAIRHVFITHQHSDHNADYGALMLLAWG
CCEEEEEECCCEEEEECCCHHHHHHHHCCCHHHHHHHHHHEECCCCCCCCCCEEEEEEEC
TDLAGPVDAWGPPPLAAMTARFLELYDYDIRTRIADEGRPPLAPMLHPHELTEGGLVMQD
CCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCCCCCHHCCCCCEEEEC
ANVKVTSALVKHPPVSPAFAYRFDAADRSIVISGDTAPSENLVRLAHGADVLVHEVMHLP
CCCEEHHHHHHCCCCCCHHEEEECCCCCEEEEECCCCCCCHHEEHHCCHHHHHHHHHHCC
SLDKLLSTEPNAKTLREHLLASHTSAEDVGRIATEAKVKTLVLSHFVPGGYPYLDDAAWL
CHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHH
DAVRPHFKGEIIVGRDLLEI
HHHCCCCCCCEEECCHHHCC
>Mature Secondary Structure
MQAFDNNRRRWMRQAGALAAGSVAASSGVWPLTSRAAQPQGTRLILLGTGGGPTPKKNRS
CCCCCCHHHHHHHHHCCCCCCCHHCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCC
APAQVIVINGVSYVVDCGNGVARQYVSAGLTLKAIRHVFITHQHSDHNADYGALMLLAWG
CCEEEEEECCCEEEEECCCHHHHHHHHCCCHHHHHHHHHHEECCCCCCCCCCEEEEEEEC
TDLAGPVDAWGPPPLAAMTARFLELYDYDIRTRIADEGRPPLAPMLHPHELTEGGLVMQD
CCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCCCCCHHCCCCCEEEEC
ANVKVTSALVKHPPVSPAFAYRFDAADRSIVISGDTAPSENLVRLAHGADVLVHEVMHLP
CCCEEHHHHHHCCCCCCHHEEEECCCCCEEEEECCCCCCCHHEEHHCCHHHHHHHHHHCC
SLDKLLSTEPNAKTLREHLLASHTSAEDVGRIATEAKVKTLVLSHFVPGGYPYLDDAAWL
CHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHH
DAVRPHFKGEIIVGRDLLEI
HHHCCCCCCCEEECCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]