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The map label for this gene is rnz [H]

Identifier: 17546881

GI number: 17546881

Start: 2345371

End: 2346387

Strand: Reverse

Name: rnz [H]

Synonym: RSc2162

Alternate gene names: 17546881

Gene position: 2346387-2345371 (Counterclockwise)

Preceding gene: 17546884

Following gene: 17546875

Centisome position: 63.14

GC content: 64.31

Gene sequence:

>1017_bases
ATGCACGGCCTGTTCGACGCCCGGCTTGTCAACGATGCCTTCGGGGATCCGGGCCTCTATCTGGATTTCCATGACGAGCG
GCGCGCCTTGCTGTTTGATCTCGGCGATCTCTCCAGGCTTCTGCCCGGCCAGCTGCTGCGTCTGTCCCATGTTTTTGTGA
CCCATACGCACATGGATCATTTCGCCGGTTTCGATCGGTTGCTGCGCGTGTCGCTCGGGCGCAAGGACCGTATCGTGGTG
CTTGGTGGGCCGGGCTTCATCGCGCAAGTGGGGCACAAGCTGAGCGCCTACACCTGGAACATGGTGGAGCGCTACACGGA
GGCATTGGTGATCGAGGCACGCGAGATCGGACTGGACGGCTGGCAGCGGCGCGTGCTTTTCTCGAGCCGTCACCACTTCG
CGCCCGAAGCCGGCGCGCGTCTCGAGCGCACGGATGACGTGCTGCACGACGAAATGACGTTTCGTGTGCGGGGCCGCTTT
GTCGATCACGACATGCCTTGCCTCGCTTTCCTGATCGAGGAGAAGGCGCGCATCGGCGTGAACAAGGATGGGCTCATGGC
GCTGGGGATGACCGCCGGCGCCTGGCTGCGCGAGTTAAAGCATGCTGTACTCAGCGGCGCCGCCGCCGACACGCCGCTGC
TGGTGCAATGGCGCGACCGGCATGGCGATCACGCCAGCACTCGGCTGGTCGGGGAGTTGTGTCAGCTGGTGCTTGATGTC
GTGCCGGGCCAGCGCATTGGCTATGTCACCGACCTGCGCTACACCGAACAAAACGTGCAGACCCTTGTGCAGCTCATGCG
TGGCGTCGATCAGTTGTATATCGAGAGCGTGTTCCTCGACGAAGACAAGGCGCATGGCCTGCGCAAGAACCACTTGACTG
CCCGTCAGGCGGGGTTGATCGCACGGGCGCTCGGGGCTGGGGCTGTCGTGCCGTTCCATTTCTCGCCCCGCTACCAGGGG
CACGGCTCCGCGCTGACGGCTGAGGTGCGTGCGGCCTGGGCTGGCTTGGCCGGCTGA

Upstream 100 bases:

>100_bases
GCTTGGCGGCCTGTCATCGATGCGTCGCCGGGACCCTATGCGCATGTCGCCATGGCTACACTGACGCTGATGGTGCACAA
ACCGCGCACTGAGGATAGCC

Downstream 100 bases:

>100_bases
GTTGCGGCAGGGCGGATTTCGTTCAAGGTTCGCGGACAAACAAAAAGGGCTCCGGTTGCTCGGAGCCCTTTTTCAATCTG
GCGGGGCGAGAGTGACTCGA

Product: ribonuclease Z

Products: NA

Alternate protein names: RNase Z; tRNA 3 endonuclease; tRNase Z [H]

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MHGLFDARLVNDAFGDPGLYLDFHDERRALLFDLGDLSRLLPGQLLRLSHVFVTHTHMDHFAGFDRLLRVSLGRKDRIVV
LGGPGFIAQVGHKLSAYTWNMVERYTEALVIEAREIGLDGWQRRVLFSSRHHFAPEAGARLERTDDVLHDEMTFRVRGRF
VDHDMPCLAFLIEEKARIGVNKDGLMALGMTAGAWLRELKHAVLSGAAADTPLLVQWRDRHGDHASTRLVGELCQLVLDV
VPGQRIGYVTDLRYTEQNVQTLVQLMRGVDQLYIESVFLDEDKAHGLRKNHLTARQAGLIARALGAGAVVPFHFSPRYQG
HGSALTAEVRAAWAGLAG

Sequences:

>Translated_338_residues
MHGLFDARLVNDAFGDPGLYLDFHDERRALLFDLGDLSRLLPGQLLRLSHVFVTHTHMDHFAGFDRLLRVSLGRKDRIVV
LGGPGFIAQVGHKLSAYTWNMVERYTEALVIEAREIGLDGWQRRVLFSSRHHFAPEAGARLERTDDVLHDEMTFRVRGRF
VDHDMPCLAFLIEEKARIGVNKDGLMALGMTAGAWLRELKHAVLSGAAADTPLLVQWRDRHGDHASTRLVGELCQLVLDV
VPGQRIGYVTDLRYTEQNVQTLVQLMRGVDQLYIESVFLDEDKAHGLRKNHLTARQAGLIARALGAGAVVPFHFSPRYQG
HGSALTAEVRAAWAGLAG
>Mature_338_residues
MHGLFDARLVNDAFGDPGLYLDFHDERRALLFDLGDLSRLLPGQLLRLSHVFVTHTHMDHFAGFDRLLRVSLGRKDRIVV
LGGPGFIAQVGHKLSAYTWNMVERYTEALVIEAREIGLDGWQRRVLFSSRHHFAPEAGARLERTDDVLHDEMTFRVRGRF
VDHDMPCLAFLIEEKARIGVNKDGLMALGMTAGAWLRELKHAVLSGAAADTPLLVQWRDRHGDHASTRLVGELCQLVLDV
VPGQRIGYVTDLRYTEQNVQTLVQLMRGVDQLYIESVFLDEDKAHGLRKNHLTARQAGLIARALGAGAVVPFHFSPRYQG
HGSALTAEVRAAWAGLAG

Specific function: Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA [H]

COG id: COG1234

COG function: function code R; Metal-dependent hydrolases of the beta-lactamase superfamily III

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase Z family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: =3.1.26.11 [H]

Molecular weight: Translated: 37777; Mature: 37777

Theoretical pI: Translated: 7.36; Mature: 7.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHGLFDARLVNDAFGDPGLYLDFHDERRALLFDLGDLSRLLPGQLLRLSHVFVTHTHMDH
CCCCCHHHHHHHCCCCCCEEEEECCCCCEEEEEHHHHHHHCHHHHHHHHHHHEEECHHHH
FAGFDRLLRVSLGRKDRIVVLGGPGFIAQVGHKLSAYTWNMVERYTEALVIEAREIGLDG
HHHHHHHHHHHCCCCCEEEEEECCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCH
WQRRVLFSSRHHFAPEAGARLERTDDVLHDEMTFRVRGRFVDHDMPCLAFLIEEKARIGV
HHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCEEEEEECEECCCCCHHHHHHHHHHHHCCC
NKDGLMALGMTAGAWLRELKHAVLSGAAADTPLLVQWRDRHGDHASTRLVGELCQLVLDV
CCCCCEEECCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHH
VPGQRIGYVTDLRYTEQNVQTLVQLMRGVDQLYIESVFLDEDKAHGLRKNHLTARQAGLI
CCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHEECCHHHCCCHHHCCHHHHHHHH
ARALGAGAVVPFHFSPRYQGHGSALTAEVRAAWAGLAG
HHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHCCCC
>Mature Secondary Structure
MHGLFDARLVNDAFGDPGLYLDFHDERRALLFDLGDLSRLLPGQLLRLSHVFVTHTHMDH
CCCCCHHHHHHHCCCCCCEEEEECCCCCEEEEEHHHHHHHCHHHHHHHHHHHEEECHHHH
FAGFDRLLRVSLGRKDRIVVLGGPGFIAQVGHKLSAYTWNMVERYTEALVIEAREIGLDG
HHHHHHHHHHHCCCCCEEEEEECCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCH
WQRRVLFSSRHHFAPEAGARLERTDDVLHDEMTFRVRGRFVDHDMPCLAFLIEEKARIGV
HHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCEEEEEECEECCCCCHHHHHHHHHHHHCCC
NKDGLMALGMTAGAWLRELKHAVLSGAAADTPLLVQWRDRHGDHASTRLVGELCQLVLDV
CCCCCEEECCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHH
VPGQRIGYVTDLRYTEQNVQTLVQLMRGVDQLYIESVFLDEDKAHGLRKNHLTARQAGLI
CCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHEECCHHHCCCHHHCCHHHHHHHH
ARALGAGAVVPFHFSPRYQGHGSALTAEVRAAWAGLAG
HHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10567266 [H]