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The map label for this gene is ygfU [H]

Identifier: 17546837

GI number: 17546837

Start: 2294273

End: 2295679

Strand: Direct

Name: ygfU [H]

Synonym: RSc2118

Alternate gene names: 17546837

Gene position: 2294273-2295679 (Clockwise)

Preceding gene: 17546836

Following gene: 17546838

Centisome position: 61.73

GC content: 69.44

Gene sequence:

>1407_bases
ATGGCAAGCACCCTCGCCGCCCCGCCGGCGGACCTGACCAACGAGCGCGTCGCCTATGCCCGCCTGTTCGCCCTCGGCCT
GCAACATGTCCTGGTGATGTATGCAGGCACCGTGGCGGTGCCGCTGATCGTGGGCAGCGCACTGCATCTGCCCAAGGAGC
AGCTCGCCTTCCTGATCAACGCCGACCTGTTCGCCGCCGGCGTGGCGACGCTGATCCAGTCCCTGGGCGTGTGGAAGTTC
GGCATCCGCATGCCGGTGATGATGGGCGTGACGTTCGCCTCGGTGGGCCCGATGATCGCCATCGGCGGCGACCCGGGCAT
CGGCCTGCTGGGCATCTACGGCGCGGTCATCGCGGCGGGGCTGTTCGGCATCGTAATCGCGCCGCTGATGGGGCGCGTGC
TGGGGCTGTTCCCGCCGGTGGTGACCGGCACCGTCATCACGCTGATCGGCGTGTCGCTGATGGGCGTGGGCATCAACTGG
GCCGCGGGCGGCCAGCCCACCCTCCAGGCCATGGTGGACGGCGTGCTCAGGACCGTGCCCAACCCGGCCTACGGCGACCC
GGGCGGCCTGGCGATCGCGCTGTCGGTACTGGTCATCATCCTGCTGCTGACCAAGTACGGACGCGGCCTGATCGGCAACA
TCGCAGTGCTGCTGGGCGTCGCCTGCGGCACCCTGATCGCCATGGCGGCCGGCAAGGTCAGTTTCGCGGGCGTGGCCGAC
GCCGACTGGATGGCCGTCATCACGCCGCTGCACTTCGGCATGCCGACCTTCCACGCCGGCGCCGTCGCCTCGATGTGCGT
GGTGATGCTGATCACGCTGGTGGAATCGACCGGCATGTTCCTGGCGCTGGCCGAGATCACCGGCAAGACGCTCACGCATG
ACGACCTGACCCGCGGCCTGCGCGCCGACGGCCTGGGCTCGGTGATCGGCGGCCTGTTCAACACCTTTCCCTACACCTCG
TTCTCGCAGAACGTCGGGCTGGTGACCGTCACCGGCGTGCGCTCGCGCTTCGTGGCGGCGGCCGGCGGCGTGATCCTGAT
CGCGCTGGGGCTGTTCCCGAAGATGGCGCACGTGGTGGCCTCGGTGCCCGCCTTCGTGCTGGGCGGCGCGGGCATCGTGA
TGTTCGGCATGGTGGCCGCCACGGGCGTGCGCATCCTCGGCTCGATCGACTTCAACCGGCATCGCCACAACCTGTTCATC
GTGGCCATCGCGATCGGCTTCGGCATGATCCCGACGCTGGCGCCGGCCTTCTTCCAGTACCTGCCGCGCTGGCTGGAGCC
GGTCACGCACAGCGGCATCGTGCTGGGCACGCTGGTGGCGGTGATCCTGAACCTGTACTACAACGGCATGCAGCCGGCCG
AGCACGCCATGCGCGCGGCCGCGGCCACCACGCACAGCGCGGAGTGA

Upstream 100 bases:

>100_bases
CCCTCTAGCCACCCGGTTTTGCCGACCCGGCGAGCCGGCCCGACAGAGGCTGGCCGCCACCGGCCGGATGCCATCCGGCC
CACCGCCACAAGGAGACCCC

Downstream 100 bases:

>100_bases
GCGCATGACCACCCACCGCACCAGCTCCGACCCGCTCCTGATCGCCCGCCACGCCGACGTGCTGGTCACCATGGACGCGC
AGCGCCGCGAGATCGCCGAC

Product: xanthine permease transmembrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 468; Mature: 467

Protein sequence:

>468_residues
MASTLAAPPADLTNERVAYARLFALGLQHVLVMYAGTVAVPLIVGSALHLPKEQLAFLINADLFAAGVATLIQSLGVWKF
GIRMPVMMGVTFASVGPMIAIGGDPGIGLLGIYGAVIAAGLFGIVIAPLMGRVLGLFPPVVTGTVITLIGVSLMGVGINW
AAGGQPTLQAMVDGVLRTVPNPAYGDPGGLAIALSVLVIILLLTKYGRGLIGNIAVLLGVACGTLIAMAAGKVSFAGVAD
ADWMAVITPLHFGMPTFHAGAVASMCVVMLITLVESTGMFLALAEITGKTLTHDDLTRGLRADGLGSVIGGLFNTFPYTS
FSQNVGLVTVTGVRSRFVAAAGGVILIALGLFPKMAHVVASVPAFVLGGAGIVMFGMVAATGVRILGSIDFNRHRHNLFI
VAIAIGFGMIPTLAPAFFQYLPRWLEPVTHSGIVLGTLVAVILNLYYNGMQPAEHAMRAAAATTHSAE

Sequences:

>Translated_468_residues
MASTLAAPPADLTNERVAYARLFALGLQHVLVMYAGTVAVPLIVGSALHLPKEQLAFLINADLFAAGVATLIQSLGVWKF
GIRMPVMMGVTFASVGPMIAIGGDPGIGLLGIYGAVIAAGLFGIVIAPLMGRVLGLFPPVVTGTVITLIGVSLMGVGINW
AAGGQPTLQAMVDGVLRTVPNPAYGDPGGLAIALSVLVIILLLTKYGRGLIGNIAVLLGVACGTLIAMAAGKVSFAGVAD
ADWMAVITPLHFGMPTFHAGAVASMCVVMLITLVESTGMFLALAEITGKTLTHDDLTRGLRADGLGSVIGGLFNTFPYTS
FSQNVGLVTVTGVRSRFVAAAGGVILIALGLFPKMAHVVASVPAFVLGGAGIVMFGMVAATGVRILGSIDFNRHRHNLFI
VAIAIGFGMIPTLAPAFFQYLPRWLEPVTHSGIVLGTLVAVILNLYYNGMQPAEHAMRAAAATTHSAE
>Mature_467_residues
ASTLAAPPADLTNERVAYARLFALGLQHVLVMYAGTVAVPLIVGSALHLPKEQLAFLINADLFAAGVATLIQSLGVWKFG
IRMPVMMGVTFASVGPMIAIGGDPGIGLLGIYGAVIAAGLFGIVIAPLMGRVLGLFPPVVTGTVITLIGVSLMGVGINWA
AGGQPTLQAMVDGVLRTVPNPAYGDPGGLAIALSVLVIILLLTKYGRGLIGNIAVLLGVACGTLIAMAAGKVSFAGVADA
DWMAVITPLHFGMPTFHAGAVASMCVVMLITLVESTGMFLALAEITGKTLTHDDLTRGLRADGLGSVIGGLFNTFPYTSF
SQNVGLVTVTGVRSRFVAAAGGVILIALGLFPKMAHVVASVPAFVLGGAGIVMFGMVAATGVRILGSIDFNRHRHNLFIV
AIAIGFGMIPTLAPAFFQYLPRWLEPVTHSGIVLGTLVAVILNLYYNGMQPAEHAMRAAAATTHSAE

Specific function: Unknown

COG id: COG2233

COG function: function code F; Xanthine/uracil permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) subfamily [H]

Homologues:

Organism=Homo sapiens, GI44680148, Length=230, Percent_Identity=31.304347826087, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI40316845, Length=230, Percent_Identity=31.304347826087, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI44680145, Length=191, Percent_Identity=33.5078534031414, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI44680143, Length=191, Percent_Identity=33.5078534031414, Blast_Score=88, Evalue=2e-17,
Organism=Escherichia coli, GI87082181, Length=455, Percent_Identity=52.7472527472528, Blast_Score=472, Evalue=1e-134,
Organism=Escherichia coli, GI1790087, Length=468, Percent_Identity=30.3418803418803, Blast_Score=176, Evalue=2e-45,
Organism=Escherichia coli, GI87082178, Length=464, Percent_Identity=28.6637931034483, Blast_Score=135, Evalue=6e-33,
Organism=Escherichia coli, GI87081818, Length=415, Percent_Identity=28.6746987951807, Blast_Score=115, Evalue=6e-27,
Organism=Escherichia coli, GI1788843, Length=393, Percent_Identity=28.2442748091603, Blast_Score=115, Evalue=7e-27,
Organism=Caenorhabditis elegans, GI17558856, Length=244, Percent_Identity=28.2786885245902, Blast_Score=86, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI71993493, Length=440, Percent_Identity=23.4090909090909, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17542260, Length=187, Percent_Identity=29.4117647058824, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17541904, Length=426, Percent_Identity=21.1267605633803, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21356175, Length=459, Percent_Identity=25.0544662309368, Blast_Score=99, Evalue=5e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017588
- InterPro:   IPR006042
- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 48144; Mature: 48013

Theoretical pI: Translated: 9.01; Mature: 9.01

Prosite motif: PS01116 XANTH_URACIL_PERMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
ASTLAAPPADLTNERVAYARLFALGLQHVLVMYAGTVAVPLIVGSALHLPKEQLAFLIN
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH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HHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]