Click here to switch to the map view.

The map label for this gene is nahR [H]

Identifier: 17546813

GI number: 17546813

Start: 2266198

End: 2267148

Strand: Reverse

Name: nahR [H]

Synonym: RSc2094

Alternate gene names: 17546813

Gene position: 2267148-2266198 (Counterclockwise)

Preceding gene: 17546827

Following gene: 17546811

Centisome position: 61.0

GC content: 67.61

Gene sequence:

>951_bases
ATGCAGATGCACGGCAAAGACCACCTCGATACCTACCTCCTGCGCGTCCTGTACACGCTGCTGACCGAGCAGAGCGTGAC
GCGCACGGCTGTCAAGCTCGGGCAATCGCAGCCGGCCATCAGCAACACGCTCAAGCGGCTGCGGGAGATCACCGGCGACG
CCATCCTCGTGCGCGGCAAGAACGGTATGGTGCCCACCGAGCGCGGCCATGAGCTGCTGGCGCTGGCGCAGCAGAGCCTG
GAGGCGATGGAGCGCATCGCCCGGCCGTCGCAGGCGTTCGACCCCGCCACCACCACGCGCACCTTCCACCTCGGCGCGCC
GGACTATCTCGACGCCTTCTTCCTGCCCAACATCATCGAGCGCCTGCGCAAGCACGCGCCGCAGGCCAGGCTGATCGTGC
ATCCGCTCAACGCGGGCGTCGATTACCTGGCCGCGCTGGAGCAGGGCGGCATGGACCTGGTGATCGGCAACTGGCTCTCG
CCGCCCGAGCACCTGCACATTTCGCCGCTGTTCGACGATGAGGTCGTCTGCATGCTGGGCGCCCAGCATCCGCTGGCGCG
CAAGGGCCTCTCGCTCAAGCACTACATCGAGATGCCGCACCTGGCCCCGGCACCGTACGCCGTCATGCAGCGCAGCATGA
TCGACCAGGCACTCGCCGAGCAGGGGCTGAAGCGGCGGATCCAGGTGTCGTTGCCGTATTTCGGGCTGGTGCCCTATGTG
CTGATGCGCACGGACCTGGTCTTCACGACCGGCCGGCAATTTGCGGCGCATTGCGCACAGTACCTGCCGGTCCGCATCCT
GCCGGCTCCGGTGGCCTTCCCCAAGATGCGCTTCTACCAGCTCTGGCACGAGCGCAGCCACGCCGCGCCGGATGTGATGT
GGCTGCGCAGGATGATCGGCGAGGTGGCGGCGGAGCTGCCGCAGCATCCTCAGCTGGAGACGGCGGCCTGA

Upstream 100 bases:

>100_bases
TACCCACCGGCCGCGATCTGGCGGCGCGCCCGGCAGGTGACTTACACTGAGTCGACTCCCCCGCGATGTTTCCGGTGGCG
CGCCACCGCCCGCGCGCCCG

Downstream 100 bases:

>100_bases
GCCGGCGGCGCCCCGGTACGGCTCGCCTGACGCCTACTTGCCGCCGGCAACCGCCTTCCCGTAGTTCGGAAAGAACACCT
GCTCCCCGTTCACCTTGAAC

Product: transcription regulator protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MQMHGKDHLDTYLLRVLYTLLTEQSVTRTAVKLGQSQPAISNTLKRLREITGDAILVRGKNGMVPTERGHELLALAQQSL
EAMERIARPSQAFDPATTTRTFHLGAPDYLDAFFLPNIIERLRKHAPQARLIVHPLNAGVDYLAALEQGGMDLVIGNWLS
PPEHLHISPLFDDEVVCMLGAQHPLARKGLSLKHYIEMPHLAPAPYAVMQRSMIDQALAEQGLKRRIQVSLPYFGLVPYV
LMRTDLVFTTGRQFAAHCAQYLPVRILPAPVAFPKMRFYQLWHERSHAAPDVMWLRRMIGEVAAELPQHPQLETAA

Sequences:

>Translated_316_residues
MQMHGKDHLDTYLLRVLYTLLTEQSVTRTAVKLGQSQPAISNTLKRLREITGDAILVRGKNGMVPTERGHELLALAQQSL
EAMERIARPSQAFDPATTTRTFHLGAPDYLDAFFLPNIIERLRKHAPQARLIVHPLNAGVDYLAALEQGGMDLVIGNWLS
PPEHLHISPLFDDEVVCMLGAQHPLARKGLSLKHYIEMPHLAPAPYAVMQRSMIDQALAEQGLKRRIQVSLPYFGLVPYV
LMRTDLVFTTGRQFAAHCAQYLPVRILPAPVAFPKMRFYQLWHERSHAAPDVMWLRRMIGEVAAELPQHPQLETAA
>Mature_316_residues
MQMHGKDHLDTYLLRVLYTLLTEQSVTRTAVKLGQSQPAISNTLKRLREITGDAILVRGKNGMVPTERGHELLALAQQSL
EAMERIARPSQAFDPATTTRTFHLGAPDYLDAFFLPNIIERLRKHAPQARLIVHPLNAGVDYLAALEQGGMDLVIGNWLS
PPEHLHISPLFDDEVVCMLGAQHPLARKGLSLKHYIEMPHLAPAPYAVMQRSMIDQALAEQGLKRRIQVSLPYFGLVPYV
LMRTDLVFTTGRQFAAHCAQYLPVRILPAPVAFPKMRFYQLWHERSHAAPDVMWLRRMIGEVAAELPQHPQLETAA

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=304, Percent_Identity=28.2894736842105, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI1790147, Length=306, Percent_Identity=25.4901960784314, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790262, Length=177, Percent_Identity=32.2033898305085, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI87081904, Length=253, Percent_Identity=26.4822134387352, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35589; Mature: 35589

Theoretical pI: Translated: 8.98; Mature: 8.98

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQMHGKDHLDTYLLRVLYTLLTEQSVTRTAVKLGQSQPAISNTLKRLREITGDAILVRGK
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCEEEEECC
NGMVPTERGHELLALAQQSLEAMERIARPSQAFDPATTTRTFHLGAPDYLDAFFLPNIIE
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHH
RLRKHAPQARLIVHPLNAGVDYLAALEQGGMDLVIGNWLSPPEHLHISPLFDDEVVCMLG
HHHHHCCCCEEEEEECCCCHHHHHHHHHCCCEEEECCCCCCCCCEEECCCCCCCHHEEEC
AQHPLARKGLSLKHYIEMPHLAPAPYAVMQRSMIDQALAEQGLKRRIQVSLPYFGLVPYV
CCCCHHHHCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHH
LMRTDLVFTTGRQFAAHCAQYLPVRILPAPVAFPKMRFYQLWHERSHAAPDVMWLRRMIG
HHHHHHHHCCCHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHH
EVAAELPQHPQLETAA
HHHHHCCCCCCCCCCC
>Mature Secondary Structure
MQMHGKDHLDTYLLRVLYTLLTEQSVTRTAVKLGQSQPAISNTLKRLREITGDAILVRGK
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCEEEEECC
NGMVPTERGHELLALAQQSLEAMERIARPSQAFDPATTTRTFHLGAPDYLDAFFLPNIIE
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHH
RLRKHAPQARLIVHPLNAGVDYLAALEQGGMDLVIGNWLSPPEHLHISPLFDDEVVCMLG
HHHHHCCCCEEEEEECCCCHHHHHHHHHCCCEEEECCCCCCCCCEEECCCCCCCHHEEEC
AQHPLARKGLSLKHYIEMPHLAPAPYAVMQRSMIDQALAEQGLKRRIQVSLPYFGLVPYV
CCCCHHHHCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHH
LMRTDLVFTTGRQFAAHCAQYLPVRILPAPVAFPKMRFYQLWHERSHAAPDVMWLRRMIG
HHHHHHHHCCCHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHH
EVAAELPQHPQLETAA
HHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]