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The map label for this gene is tctD [H]

Identifier: 17546455

GI number: 17546455

Start: 1858354

End: 1859046

Strand: Reverse

Name: tctD [H]

Synonym: RSc1736

Alternate gene names: 17546455

Gene position: 1859046-1858354 (Counterclockwise)

Preceding gene: 17546457

Following gene: 17546454

Centisome position: 50.02

GC content: 71.14

Gene sequence:

>693_bases
ATGCGCATCCTGTTGGTGGAAGACAACCCGAAGCTGGCCGGCACGCTGGAGGAAGCCCTGGGCCAGGCCGGCTTCACGGT
CGACTGCGTGCACGACGGCCACGCCGCCGACCTGCTGCTGACCACGCAGGACTACGCCCTGCTGCTGCTCGACCTCGGCC
TGCCCCGGCTCGACGGGCTCGAAGTGCTGCGCCGCCTGCGCCTGCGCCGCAATCCGCTGCCGGTGATGATCCTGACCGCG
CACGGCGCCGTGGAAGAGCGCGTGCGCGGCCTGAACCTCGGCGCCGACGATTACCTGACCAAACCGTTCGACCTGACCGA
GGTGGAGGCGCGCGCCCGCGCGCTGATCCGCCGCAGCCACGGCCACGAGCGCACGCAGCTGCAATGCGGCCCCCTGCACT
ACGACGGCACCAGCGGCGCCTTCACCCTGCGCGGCGAGGCGCTGGCGCTGACCGGCCGCGAGCGCGCGGTGCTGGAAGTC
CTGATGCTGCGCGATGGCCGCGCCGTCAACAAGGCCGCCATCTCGGAGAAGATCTTCGGCATCAACGAATCGGTCAACGC
CGACGCCATCGAGATCTACGTGCACCGGCTGCGCAAGAAGCTCGACGGCAGCGGCGTGGCCATCGTCATGCTGCGCGGGC
TGGGCTACCTGCTCGAGGCCGTGCCGCAGGCGCCGGCCGCCGTCGGCCGATGA

Upstream 100 bases:

>100_bases
CCCGTGGCGCGCAGGCGCCAGGGGGTTTCCCTAGCATCAAAAGCCGCGCGGATGCGGTATTCCTCTGCGCCTTGGTCGAA
GACGTTGGAAGCAGCAAGCG

Downstream 100 bases:

>100_bases
GCGCCCCCAGCCTGCGCCGGCAACTGCTGCTGTGGCTGCTGCTGCCGTTGCTGGGCCTGCTGGCGCTCGATGCCTGGCTG
ACCTACGGCCGCGCCATGGC

Product: two-component response regulator transcription regulator protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 230; Mature: 230

Protein sequence:

>230_residues
MRILLVEDNPKLAGTLEEALGQAGFTVDCVHDGHAADLLLTTQDYALLLLDLGLPRLDGLEVLRRLRLRRNPLPVMILTA
HGAVEERVRGLNLGADDYLTKPFDLTEVEARARALIRRSHGHERTQLQCGPLHYDGTSGAFTLRGEALALTGRERAVLEV
LMLRDGRAVNKAAISEKIFGINESVNADAIEIYVHRLRKKLDGSGVAIVMLRGLGYLLEAVPQAPAAVGR

Sequences:

>Translated_230_residues
MRILLVEDNPKLAGTLEEALGQAGFTVDCVHDGHAADLLLTTQDYALLLLDLGLPRLDGLEVLRRLRLRRNPLPVMILTA
HGAVEERVRGLNLGADDYLTKPFDLTEVEARARALIRRSHGHERTQLQCGPLHYDGTSGAFTLRGEALALTGRERAVLEV
LMLRDGRAVNKAAISEKIFGINESVNADAIEIYVHRLRKKLDGSGVAIVMLRGLGYLLEAVPQAPAAVGR
>Mature_230_residues
MRILLVEDNPKLAGTLEEALGQAGFTVDCVHDGHAADLLLTTQDYALLLLDLGLPRLDGLEVLRRLRLRRNPLPVMILTA
HGAVEERVRGLNLGADDYLTKPFDLTEVEARARALIRRSHGHERTQLQCGPLHYDGTSGAFTLRGEALALTGRERAVLEV
LMLRDGRAVNKAAISEKIFGINESVNADAIEIYVHRLRKKLDGSGVAIVMLRGLGYLLEAVPQAPAAVGR

Specific function: Transcriptional activator of the tctI tricarboxylate transport system operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789402, Length=218, Percent_Identity=42.2018348623853, Blast_Score=160, Evalue=7e-41,
Organism=Escherichia coli, GI87082012, Length=225, Percent_Identity=36.8888888888889, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1786784, Length=225, Percent_Identity=38.2222222222222, Blast_Score=147, Evalue=5e-37,
Organism=Escherichia coli, GI1790552, Length=220, Percent_Identity=38.1818181818182, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1787375, Length=221, Percent_Identity=35.2941176470588, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI1789809, Length=228, Percent_Identity=33.7719298245614, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI2367329, Length=229, Percent_Identity=37.117903930131, Blast_Score=110, Evalue=9e-26,
Organism=Escherichia coli, GI1788394, Length=224, Percent_Identity=32.1428571428571, Blast_Score=98, Evalue=4e-22,
Organism=Escherichia coli, GI1786599, Length=223, Percent_Identity=33.1838565022422, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI1790860, Length=221, Percent_Identity=30.7692307692308, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1786911, Length=222, Percent_Identity=29.7297297297297, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1787229, Length=227, Percent_Identity=29.9559471365639, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1790299, Length=148, Percent_Identity=33.7837837837838, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1788550, Length=138, Percent_Identity=34.0579710144928, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1790863, Length=228, Percent_Identity=27.1929824561404, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI1788713, Length=120, Percent_Identity=33.3333333333333, Blast_Score=67, Evalue=7e-13,
Organism=Escherichia coli, GI1790437, Length=119, Percent_Identity=30.2521008403361, Blast_Score=64, Evalue=9e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25136; Mature: 25136

Theoretical pI: Translated: 7.22; Mature: 7.22

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILLVEDNPKLAGTLEEALGQAGFTVDCVHDGHAADLLLTTQDYALLLLDLGLPRLDGL
CEEEEEECCCCHHHHHHHHHCCCCCEEEEEECCCCEEEEEECCCCEEEEEECCCCCCCHH
EVLRRLRLRRNPLPVMILTAHGAVEERVRGLNLGADDYLTKPFDLTEVEARARALIRRSH
HHHHHHHHCCCCCCEEEEECCCCHHHHHHCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHC
GHERTQLQCGPLHYDGTSGAFTLRGEALALTGRERAVLEVLMLRDGRAVNKAAISEKIFG
CCCCCEEEECCEEECCCCCEEEEECCEEEECCCHHHHHHHHHHCCCCCHHHHHHHHHHCC
INESVNADAIEIYVHRLRKKLDGSGVAIVMLRGLGYLLEAVPQAPAAVGR
CCCCCCCHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MRILLVEDNPKLAGTLEEALGQAGFTVDCVHDGHAADLLLTTQDYALLLLDLGLPRLDGL
CEEEEEECCCCHHHHHHHHHCCCCCEEEEEECCCCEEEEEECCCCEEEEEECCCCCCCHH
EVLRRLRLRRNPLPVMILTAHGAVEERVRGLNLGADDYLTKPFDLTEVEARARALIRRSH
HHHHHHHHCCCCCCEEEEECCCCHHHHHHCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHC
GHERTQLQCGPLHYDGTSGAFTLRGEALALTGRERAVLEVLMLRDGRAVNKAAISEKIFG
CCCCCEEEECCEEECCCCCEEEEECCEEEECCCHHHHHHHHHHCCCCCHHHHHHHHHHCC
INESVNADAIEIYVHRLRKKLDGSGVAIVMLRGLGYLLEAVPQAPAAVGR
CCCCCCCHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2666399; 11083839; 11677609 [H]