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The map label for this gene is qseC [H]

Identifier: 17546454

GI number: 17546454

Start: 1856942

End: 1858357

Strand: Reverse

Name: qseC [H]

Synonym: RSc1735

Alternate gene names: 17546454

Gene position: 1858357-1856942 (Counterclockwise)

Preceding gene: 17546455

Following gene: 17546453

Centisome position: 50.0

GC content: 73.8

Gene sequence:

>1416_bases
ATGAGCGCCCCCAGCCTGCGCCGGCAACTGCTGCTGTGGCTGCTGCTGCCGTTGCTGGGCCTGCTGGCGCTCGATGCCTG
GCTGACCTACGGCCGCGCCATGGCCGCCGCCCACCACGCCTTCGACCGCACGCTGCAGGGCTCGCTCAAGGCCATGCGCG
AAGGCATCCGGCTGCGCGACGGGCAGTTCGCCATCAACCTGCCCTACCTGGCCCTGGAGATCTTCGAATCGGAGGCGGGC
AGCAGCATCTTCTACCGCATCCTCGACGCGCGCGGCACCACCCTGACCGGCTACGACGAACTGCCCCTGCCGCCCACCCG
GCCGCCCGAGCCCTACCGCACGGCGTTCTACGATGCCGTGCTGCGCGACATGCGGGTCCGGGTGGCGGCACAGCGGCTGC
CGGTGCGCGACGCCGCCTCCGCGCAGATTCAGGTGGTGTGGGTGCTGGTGGGCGAGTCGGTCGAGCCGCGCGAAGCCCTG
GCGCACGACATGCTGACGGGCTCGCTGCTGCAGGAGGGGCTGCTGGTGCTGCTGGCGCTCGGCATCGTCTGGCTGGGCGT
GCGGCGAGGCCTGCGGCCGCTGCGCCAGCTCAGCGCCAGCGTGGCCGCGCGCCATGCCGACGAGCTCGCCCCGCTGCCGC
AGCACGGCCTGCCGGCCGAGGTGACCCCGCTGGTGGCCGCCATCAACCAGTATGTGGCGCGGCTGCTGCGCATGCTCGAC
GCCCGCAAGCGTTTCTTCGCCGATGCGGCGCATCAGCTCAAGACGCCGCTGGCCGTGATCCAGGCCCAATCGGAGCTGGC
GCTGCGCGAGCCCGACGGCAACCGCATCCGCCGCCACCTCGCGCCGCTGCACGACACGGTGCGGCAGGCGGCCAAGGGCG
TGCAGCAGCTGCTGTCGCTGTCGCGGCTGGAGCCGGACAGCGGCTATGCCCCGTCGCTGCAGCCGCTGCGGCTCGACACG
CTGGCCGGCGAGGTGGCGCTGGAGCTGGCGCCGGTGGCGCACCGCGCCGGCATCGACCTCGGCTTCGAGGGCGAGCCCGT
GACAGTCGCGGCCGAACCGCAATGGCTGCAGGAACTGGTGGGCAATCTGCTCGACAACGCGATCCGCTATGCCGGCCCCG
ACGCGCGCGTGACGCTGCGGGTCGCGCGGCAGGCGGCGCCCGGCCAGGACACCGGCGCGCTGCTGCAGGTGGAAGACAAC
GGCCCCGGCATCGCCGAGGCGGAGCGCGCCGCCGTCTTCGGCCGCTTCTACCGTGGCAGCACCGCCCAGGCCCAGGAAGG
CAGCGGGCTGGGCCTGGCCATCGTGCGCGAAATCGCCCGCGTGCACGGCGCCACCGTCGCGCTGTCGGACACCGCGGGCG
GCGGCCTGACCGTCAGCGTGCGCTTCACCCAGGCCGACCGCGCGCCAGCCGGCTGA

Upstream 100 bases:

>100_bases
TGCGCAAGAAGCTCGACGGCAGCGGCGTGGCCATCGTCATGCTGCGCGGGCTGGGCTACCTGCTCGAGGCCGTGCCGCAG
GCGCCGGCCGCCGTCGGCCG

Downstream 100 bases:

>100_bases
AGCAACCGCCCCGCACGTCTTCAGGTTGCTGCGGGACAACAAGACACGCGAGCCATGCCGAGGCCCGGCCGGCGACGCGC
CATCGCGGCGCACCGTCTTC

Product: two-component transmembrane sensor kinase transcription regulator protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 471; Mature: 470

Protein sequence:

>471_residues
MSAPSLRRQLLLWLLLPLLGLLALDAWLTYGRAMAAAHHAFDRTLQGSLKAMREGIRLRDGQFAINLPYLALEIFESEAG
SSIFYRILDARGTTLTGYDELPLPPTRPPEPYRTAFYDAVLRDMRVRVAAQRLPVRDAASAQIQVVWVLVGESVEPREAL
AHDMLTGSLLQEGLLVLLALGIVWLGVRRGLRPLRQLSASVAARHADELAPLPQHGLPAEVTPLVAAINQYVARLLRMLD
ARKRFFADAAHQLKTPLAVIQAQSELALREPDGNRIRRHLAPLHDTVRQAAKGVQQLLSLSRLEPDSGYAPSLQPLRLDT
LAGEVALELAPVAHRAGIDLGFEGEPVTVAAEPQWLQELVGNLLDNAIRYAGPDARVTLRVARQAAPGQDTGALLQVEDN
GPGIAEAERAAVFGRFYRGSTAQAQEGSGLGLAIVREIARVHGATVALSDTAGGGLTVSVRFTQADRAPAG

Sequences:

>Translated_471_residues
MSAPSLRRQLLLWLLLPLLGLLALDAWLTYGRAMAAAHHAFDRTLQGSLKAMREGIRLRDGQFAINLPYLALEIFESEAG
SSIFYRILDARGTTLTGYDELPLPPTRPPEPYRTAFYDAVLRDMRVRVAAQRLPVRDAASAQIQVVWVLVGESVEPREAL
AHDMLTGSLLQEGLLVLLALGIVWLGVRRGLRPLRQLSASVAARHADELAPLPQHGLPAEVTPLVAAINQYVARLLRMLD
ARKRFFADAAHQLKTPLAVIQAQSELALREPDGNRIRRHLAPLHDTVRQAAKGVQQLLSLSRLEPDSGYAPSLQPLRLDT
LAGEVALELAPVAHRAGIDLGFEGEPVTVAAEPQWLQELVGNLLDNAIRYAGPDARVTLRVARQAAPGQDTGALLQVEDN
GPGIAEAERAAVFGRFYRGSTAQAQEGSGLGLAIVREIARVHGATVALSDTAGGGLTVSVRFTQADRAPAG
>Mature_470_residues
SAPSLRRQLLLWLLLPLLGLLALDAWLTYGRAMAAAHHAFDRTLQGSLKAMREGIRLRDGQFAINLPYLALEIFESEAGS
SIFYRILDARGTTLTGYDELPLPPTRPPEPYRTAFYDAVLRDMRVRVAAQRLPVRDAASAQIQVVWVLVGESVEPREALA
HDMLTGSLLQEGLLVLLALGIVWLGVRRGLRPLRQLSASVAARHADELAPLPQHGLPAEVTPLVAAINQYVARLLRMLDA
RKRFFADAAHQLKTPLAVIQAQSELALREPDGNRIRRHLAPLHDTVRQAAKGVQQLLSLSRLEPDSGYAPSLQPLRLDTL
AGEVALELAPVAHRAGIDLGFEGEPVTVAAEPQWLQELVGNLLDNAIRYAGPDARVTLRVARQAAPGQDTGALLQVEDNG
PGIAEAERAAVFGRFYRGSTAQAQEGSGLGLAIVREIARVHGATVALSDTAGGGLTVSVRFTQADRAPAG

Specific function: Member of a two-component regulatory system qseB/qseC. May activate qseB by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789403, Length=322, Percent_Identity=34.472049689441, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1786783, Length=299, Percent_Identity=28.7625418060201, Blast_Score=115, Evalue=8e-27,
Organism=Escherichia coli, GI1790551, Length=298, Percent_Identity=31.5436241610738, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1788279, Length=298, Percent_Identity=26.1744966442953, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1789808, Length=286, Percent_Identity=29.3706293706294, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI1786600, Length=236, Percent_Identity=29.6610169491525, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1790346, Length=279, Percent_Identity=29.0322580645161, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1786912, Length=226, Percent_Identity=29.646017699115, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1787374, Length=311, Percent_Identity=27.9742765273312, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1790861, Length=299, Percent_Identity=28.4280936454849, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1788393, Length=249, Percent_Identity=30.9236947791165, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1789149, Length=279, Percent_Identity=24.0143369175627, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI87082128, Length=250, Percent_Identity=26.8, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1788713, Length=250, Percent_Identity=24.4, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1787894, Length=254, Percent_Identity=26.3779527559055, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1790436, Length=227, Percent_Identity=27.7533039647577, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI48994928, Length=237, Percent_Identity=23.6286919831224, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1788549, Length=217, Percent_Identity=27.1889400921659, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 50929; Mature: 50798

Theoretical pI: Translated: 8.02; Mature: 8.02

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAPSLRRQLLLWLLLPLLGLLALDAWLTYGRAMAAAHHAFDRTLQGSLKAMREGIRLRD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
GQFAINLPYLALEIFESEAGSSIFYRILDARGTTLTGYDELPLPPTRPPEPYRTAFYDAV
CCEEEECCHHHHHHHHCCCCCHHHHHHHHCCCCEECCCCCCCCCCCCCCCHHHHHHHHHH
LRDMRVRVAAQRLPVRDAASAQIQVVWVLVGESVEPREALAHDMLTGSLLQEGLLVLLAL
HHHHHHHHHHHHCCCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
GIVWLGVRRGLRPLRQLSASVAARHADELAPLPQHGLPAEVTPLVAAINQYVARLLRMLD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
ARKRFFADAAHQLKTPLAVIQAQSELALREPDGNRIRRHLAPLHDTVRQAAKGVQQLLSL
HHHHHHHHHHHHHHCCHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SRLEPDSGYAPSLQPLRLDTLAGEVALELAPVAHRAGIDLGFEGEPVTVAAEPQWLQELV
HHCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCHHHHHHHH
GNLLDNAIRYAGPDARVTLRVARQAAPGQDTGALLQVEDNGPGIAEAERAAVFGRFYRGS
HHHHHHHHHHCCCCCEEEEEEHHHCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCC
TAQAQEGSGLGLAIVREIARVHGATVALSDTAGGGLTVSVRFTQADRAPAG
CCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCEEEEEEEEECCCCCCC
>Mature Secondary Structure 
SAPSLRRQLLLWLLLPLLGLLALDAWLTYGRAMAAAHHAFDRTLQGSLKAMREGIRLRD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
GQFAINLPYLALEIFESEAGSSIFYRILDARGTTLTGYDELPLPPTRPPEPYRTAFYDAV
CCEEEECCHHHHHHHHCCCCCHHHHHHHHCCCCEECCCCCCCCCCCCCCCHHHHHHHHHH
LRDMRVRVAAQRLPVRDAASAQIQVVWVLVGESVEPREALAHDMLTGSLLQEGLLVLLAL
HHHHHHHHHHHHCCCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
GIVWLGVRRGLRPLRQLSASVAARHADELAPLPQHGLPAEVTPLVAAINQYVARLLRMLD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
ARKRFFADAAHQLKTPLAVIQAQSELALREPDGNRIRRHLAPLHDTVRQAAKGVQQLLSL
HHHHHHHHHHHHHHCCHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SRLEPDSGYAPSLQPLRLDTLAGEVALELAPVAHRAGIDLGFEGEPVTVAAEPQWLQELV
HHCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCHHHHHHHH
GNLLDNAIRYAGPDARVTLRVARQAAPGQDTGALLQVEDNGPGIAEAERAAVFGRFYRGS
HHHHHHHHHHCCCCCEEEEEEHHHCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCC
TAQAQEGSGLGLAIVREIARVHGATVALSDTAGGGLTVSVRFTQADRAPAG
CCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCEEEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800; 10675023 [H]