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The map label for this gene is mgtC [H]

Identifier: 17546180

GI number: 17546180

Start: 1563766

End: 1564488

Strand: Reverse

Name: mgtC [H]

Synonym: RSc1461

Alternate gene names: 17546180

Gene position: 1564488-1563766 (Counterclockwise)

Preceding gene: 17546181

Following gene: 17546177

Centisome position: 42.1

GC content: 69.29

Gene sequence:

>723_bases
ATGACGCTGCAAGCCGTCGCCCAATTCAACGCCGCCACCCTGCTGGATTCTTTTATCAGCCTGGCGGCCGCCTTCGGGCT
CGGCTCGCTGATCGGCTTTGAGCGGCAGGTGCGCCAGCGCACGGCCGGCCTGCGCACCAACGCGCTGGTGGCGGTGTCGG
CATCGGCCTTCGTCGACATGGCCGCGCAGATCGGCTCGCCCGCCGATACCACCCGCGTGATCGCCTACGTGGTCTCGGGC
GTGGGCTTTCTGGGCGCCGGCACGATCATGAAGGAAGGGCTGAACGTGCGCGGCCTGAACACCGCCGCCACGCTGTGGGG
CTCGGCCGCCGTGGGCGCGGCGGCGGGCTCGGACCTGCTCGGCCAGGCCCTGATGATCTCGCTGTTCGTGCTGGCCTCGA
ACATCCTGCTGCGGCCCGTGGTCGACCGCATCAACCGCACGCCGCTGGACAACCAGGCCAGCGAAGTCACCTACACCGTG
CACGCCATCTCCACGCGCGAGCGCCAGAAAGACGCGCTCGCCGACCTGGAGCGCCTGCTGGAAGAGGCCAGCTACCCGAT
CAGCGATCTCTCGGTCGCGCCGTTCGGCGAGGACCACGTGGAGCTGGAGGCCATGCTGATGTCGACCGCCGTCAATGCCG
GCGAGCTGGACCGGATCGTCGGCGCGCTGGCCGCGCAGCCGCATATCGCGCAGGCGTACTGGAACCCCAGCACCACCGAG
TAA

Upstream 100 bases:

>100_bases
CCACCGGGCACCCGCTACCCGCACGGCCTGACGCGGCGCCGTGCTATAACCGTCGGCGCTTTCCCGAAGACCCCGCCTTT
CGTTACGAAGGAGCCCGCCG

Downstream 100 bases:

>100_bases
GCCCGCGCGGCCAGCCGGGCCCGGCGCGCGTCAGGCCAGCCGGAAGGCCGCGATCGCCTCGTTCAGCGCCTGCGCCTGCT
CTTCCAGCGATTCGGCCGCG

Product: transporter transmembrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 240; Mature: 239

Protein sequence:

>240_residues
MTLQAVAQFNAATLLDSFISLAAAFGLGSLIGFERQVRQRTAGLRTNALVAVSASAFVDMAAQIGSPADTTRVIAYVVSG
VGFLGAGTIMKEGLNVRGLNTAATLWGSAAVGAAAGSDLLGQALMISLFVLASNILLRPVVDRINRTPLDNQASEVTYTV
HAISTRERQKDALADLERLLEEASYPISDLSVAPFGEDHVELEAMLMSTAVNAGELDRIVGALAAQPHIAQAYWNPSTTE

Sequences:

>Translated_240_residues
MTLQAVAQFNAATLLDSFISLAAAFGLGSLIGFERQVRQRTAGLRTNALVAVSASAFVDMAAQIGSPADTTRVIAYVVSG
VGFLGAGTIMKEGLNVRGLNTAATLWGSAAVGAAAGSDLLGQALMISLFVLASNILLRPVVDRINRTPLDNQASEVTYTV
HAISTRERQKDALADLERLLEEASYPISDLSVAPFGEDHVELEAMLMSTAVNAGELDRIVGALAAQPHIAQAYWNPSTTE
>Mature_239_residues
TLQAVAQFNAATLLDSFISLAAAFGLGSLIGFERQVRQRTAGLRTNALVAVSASAFVDMAAQIGSPADTTRVIAYVVSGV
GFLGAGTIMKEGLNVRGLNTAATLWGSAAVGAAAGSDLLGQALMISLFVLASNILLRPVVDRINRTPLDNQASEVTYTVH
AISTRERQKDALADLERLLEEASYPISDLSVAPFGEDHVELEAMLMSTAVNAGELDRIVGALAAQPHIAQAYWNPSTTE

Specific function: Virulence factor required for growth in low Mg(2+) medium and for intramacrophage survival. May be involved in regulating membrane potential by activating Na(+)/K(+)-ATPase [H]

COG id: COG1285

COG function: function code S; Uncharacterized membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MgtC/SapB family [H]

Homologues:

Organism=Escherichia coli, GI1789924, Length=97, Percent_Identity=42.2680412371134, Blast_Score=73, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003416 [H]

Pfam domain/function: PF02308 MgtC [H]

EC number: NA

Molecular weight: Translated: 25187; Mature: 25056

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLQAVAQFNAATLLDSFISLAAAFGLGSLIGFERQVRQRTAGLRTNALVAVSASAFVDM
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHH
AAQIGSPADTTRVIAYVVSGVGFLGAGTIMKEGLNVRGLNTAATLWGSAAVGAAAGSDLL
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCHHHH
GQALMISLFVLASNILLRPVVDRINRTPLDNQASEVTYTVHAISTRERQKDALADLERLL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHH
EEASYPISDLSVAPFGEDHVELEAMLMSTAVNAGELDRIVGALAAQPHIAQAYWNPSTTE
HHHCCCCCCCEECCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHCCCCCCCC
>Mature Secondary Structure 
TLQAVAQFNAATLLDSFISLAAAFGLGSLIGFERQVRQRTAGLRTNALVAVSASAFVDM
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHH
AAQIGSPADTTRVIAYVVSGVGFLGAGTIMKEGLNVRGLNTAATLWGSAAVGAAAGSDLL
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCHHHH
GQALMISLFVLASNILLRPVVDRINRTPLDNQASEVTYTVHAISTRERQKDALADLERLL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHH
EEASYPISDLSVAPFGEDHVELEAMLMSTAVNAGELDRIVGALAAQPHIAQAYWNPSTTE
HHHCCCCCCCEECCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA