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The map label for this gene is rnhB

Identifier: 17546137

GI number: 17546137

Start: 1518122

End: 1518832

Strand: Direct

Name: rnhB

Synonym: RSc1418

Alternate gene names: 17546137

Gene position: 1518122-1518832 (Clockwise)

Preceding gene: 17546136

Following gene: 17546138

Centisome position: 40.85

GC content: 71.73

Gene sequence:

>711_bases
ATGACGGCCGATTCCACCGAGATTCCGCAACTCGCGCTCCCGCTGTCGCAGTCGCCGGCGGCGGGCAAGCGCGCGCGCCG
CATCCTGTGCGGCGTCGACGAGGCCGGGCGCGGGCCGCTGGCGGGGCCGGTGACGGCTGCCGCCGTGGTGCTCAATCCGC
GCAAGCCGATCCAGGGGCTGGCCGACTCCAAGGTGCTGACCGCCAAAAAGCGTGAGGCGCTGTACGACGAGATCGTCGAG
AAGGCGCTCGCGTGGCATGTGGCCGAAGCCACCGTCGAGGAGATCGATCGCATCAACATCCTGCATGCGACCATGCTGGC
GATGCAGCGCGCCGTGCAGGGCGTCGCCGCGCAAGGGGTGCTGCCCGACCTGGTGCAGGTGGACGGCAACCGTTGTCCGC
AGGTGGCGTTCGCGGTGGAGGCCATCGTCAAGGGCGATGCCCTGGTGCCGGCCATCTCGGCCGCATCGATCCTGGCCAAG
GTGACGCGCGACCGCCAACTGGCGGCCCTGCACATCGCATTTCCGCAGTACGGCTTCGACGTACACGCCGGCTACGGCAC
GCCGCAGCACCTGGCCGCCATCGAGCGGCACGGCGTGACGCCGCATCATCGCCGCTCGTTCGCCCCCGTGCGCCGCGCGC
TGGACGGTGCGCCGCCCCCGGCCGGCGACGCCGTGCCGCAGACCGACGCCAAGACGGCGTGGGCCGACTGA

Upstream 100 bases:

>100_bases
CACTTCACGCAGATGCACCTGACGCTCAAGCAGAACATGGCCGACATCGGCGCCCAGGTGGTGGTGGACCTGCTGCGCGG
CCGCGGCAAACTCTGAGACC

Downstream 100 bases:

>100_bases
CCTTCCGCTCCTCCGCCCCGTGAAGCACATCACCTCTCGCGACAACGCGGTATTCAAGCATTTGAAGGCGCTGTCGGGCT
CGACCCAGCAGCGTCGTCGC

Product: ribonuclease HII

Products: NA

Alternate protein names: RNase HII

Number of amino acids: Translated: 236; Mature: 235

Protein sequence:

>236_residues
MTADSTEIPQLALPLSQSPAAGKRARRILCGVDEAGRGPLAGPVTAAAVVLNPRKPIQGLADSKVLTAKKREALYDEIVE
KALAWHVAEATVEEIDRINILHATMLAMQRAVQGVAAQGVLPDLVQVDGNRCPQVAFAVEAIVKGDALVPAISAASILAK
VTRDRQLAALHIAFPQYGFDVHAGYGTPQHLAAIERHGVTPHHRRSFAPVRRALDGAPPPAGDAVPQTDAKTAWAD

Sequences:

>Translated_236_residues
MTADSTEIPQLALPLSQSPAAGKRARRILCGVDEAGRGPLAGPVTAAAVVLNPRKPIQGLADSKVLTAKKREALYDEIVE
KALAWHVAEATVEEIDRINILHATMLAMQRAVQGVAAQGVLPDLVQVDGNRCPQVAFAVEAIVKGDALVPAISAASILAK
VTRDRQLAALHIAFPQYGFDVHAGYGTPQHLAAIERHGVTPHHRRSFAPVRRALDGAPPPAGDAVPQTDAKTAWAD
>Mature_235_residues
TADSTEIPQLALPLSQSPAAGKRARRILCGVDEAGRGPLAGPVTAAAVVLNPRKPIQGLADSKVLTAKKREALYDEIVEK
ALAWHVAEATVEEIDRINILHATMLAMQRAVQGVAAQGVLPDLVQVDGNRCPQVAFAVEAIVKGDALVPAISAASILAKV
TRDRQLAALHIAFPQYGFDVHAGYGTPQHLAAIERHGVTPHHRRSFAPVRRALDGAPPPAGDAVPQTDAKTAWAD

Specific function: Endonuclease that specifically degrades the RNA of RNA- DNA hybrids

COG id: COG0164

COG function: function code L; Ribonuclease HII

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase HII family

Homologues:

Organism=Escherichia coli, GI1786380, Length=188, Percent_Identity=60.1063829787234, Blast_Score=225, Evalue=2e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RNH2_RALSO (Q8XZH7)

Other databases:

- EMBL:   AL646052
- RefSeq:   NP_519539.1
- ProteinModelPortal:   Q8XZH7
- SMR:   Q8XZH7
- GeneID:   1220242
- GenomeReviews:   AL646052_GR
- KEGG:   rso:RSc1418
- NMPDR:   fig|267608.1.peg.1418
- HOGENOM:   HBG584843
- OMA:   IICGVDE
- ProtClustDB:   PRK00015
- BioCyc:   RSOL267608:RSC1418-MONOMER
- BRENDA:   3.1.26.4
- GO:   GO:0005737
- HAMAP:   MF_00052_B
- InterPro:   IPR022898
- InterPro:   IPR001352
- InterPro:   IPR012337
- PANTHER:   PTHR10954

Pfam domain/function: PF01351 RNase_HII; SSF53098 RNaseH_fold

EC number: =3.1.26.4

Molecular weight: Translated: 24913; Mature: 24782

Theoretical pI: Translated: 8.27; Mature: 8.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTADSTEIPQLALPLSQSPAAGKRARRILCGVDEAGRGPLAGPVTAAAVVLNPRKPIQGL
CCCCCCCCCCEECCCCCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHEEEEECCCCCCCCC
ADSKVLTAKKREALYDEIVEKALAWHVAEATVEEIDRINILHATMLAMQRAVQGVAAQGV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
LPDLVQVDGNRCPQVAFAVEAIVKGDALVPAISAASILAKVTRDRQLAALHIAFPQYGFD
CHHHHHCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCE
VHAGYGTPQHLAAIERHGVTPHHRRSFAPVRRALDGAPPPAGDAVPQTDAKTAWAD
EECCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TADSTEIPQLALPLSQSPAAGKRARRILCGVDEAGRGPLAGPVTAAAVVLNPRKPIQGL
CCCCCCCCCEECCCCCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHEEEEECCCCCCCCC
ADSKVLTAKKREALYDEIVEKALAWHVAEATVEEIDRINILHATMLAMQRAVQGVAAQGV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
LPDLVQVDGNRCPQVAFAVEAIVKGDALVPAISAASILAKVTRDRQLAALHIAFPQYGFD
CHHHHHCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCE
VHAGYGTPQHLAAIERHGVTPHHRRSFAPVRRALDGAPPPAGDAVPQTDAKTAWAD
EECCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852