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The map label for this gene is dapC [H]

Identifier: 17546113

GI number: 17546113

Start: 1485259

End: 1486512

Strand: Reverse

Name: dapC [H]

Synonym: RSc1394

Alternate gene names: 17546113

Gene position: 1486512-1485259 (Counterclockwise)

Preceding gene: 17546120

Following gene: 17546112

Centisome position: 40.0

GC content: 68.74

Gene sequence:

>1254_bases
ATGCTTGCTCAGCCCCCCGGCCCACTCCGACCCATCCGGTCCATGCCCAACACCGTGAATCCGCGCCTGTCCAGCCTCCA
GCCGTATCCGTTCGAGAAACTGAAAGCGCTCGTCAAGGACGTGACGCCCAGCCCCGCGCATGCGCCGATCAGCTTCGGCA
TCGGCGAGCCCAAGCATCCGACGCCGGCGCTGGTGAAAGACGCGCTGACGGCCTCGCTGGCCGGACTGGCGAATTATCCC
ACGACGGCCGGCTCCGACGCGCTGCGCCAGTGCATCGCCGCCTGGCTGGAGCGCCGCTACGGCCTGCCCAAGGTCGATGC
CGCCACCGAGGTACTGCCGGTCAACGGCTCGCGCGAAGCGCTGTTCGCCTTTGCGCAGACCGTGATCGACGGCAGCAAGC
CCGGCGCGCGCGTGCTGTGCCCGAACCCGTTCTACCAGATCTACGAAGGCTCGGCCCTGCTGGCCGGCGCGCAGCCGCTG
TTCGCCAACAGCAACCCGGCGCGCAACTACGCGCCCGACTTCGACGCCATCACGCCGGAAGAATGGCGCAACGTGCAGCT
CGTCTTCGTGTGCAGCCCCGGCAACCCGACCGGCGCCGTGCTCACGCTGGAGGACTGGAAGCAGCTGTTCGCGCTGTCCG
ACCGGTACGGCTTCGTCATCGCGTCGGACGAGTGCTATTCCGAGATCTACTTCGACGAGGCCAACCCGCCGCTGGGTGCG
CTGCAGGCCGCGCACCAGCTCGGCCGCGGCTTCGAGCGGCTGGTGATGTTCTCGAGCCTGTCCAAGCGCTCCAACGTGCC
GGGCATGCGCTCGGGCTTCGTGGCGGGTGACGCCAAGCTGATCAAGGCCTACCTGCTGTATCGCACGTATCACGGCAGCG
CGATGAACCCGGCGGTGCAATCCGCCAGCATCGCGGCCTGGAACGACGAGACCCACGTGCGCGAGAACCGCGCGCAGTAC
GTCAGGAAGTTCCAGTCGGTCACGCCGATGCTGGCCGAGGTGCTGGACGTGGCCCTGCCCGATGCGGCCTTCTATCTGTG
GGCCAACGTCAAGCGCACCGGCCTGTCGGACACCGCGTTCGCGCGCGAGCTGCTGGCCGCCAAGAACGTCGCTGTGCTGC
CGGGCAGCTACCTCGCCCGCGAGGCGCACGGCGTCAACCCGGGCCAGGACTACGTCCGCATCGCGCTGGTGGCCGGCGTG
GACGAGTGCCTGGACGGCGCGCGCCGCATCGTCGAGTTCTGCCAGCAACGCTGA

Upstream 100 bases:

>100_bases
TAAAAAAACGGCGGAAAACCGCCGCTTCCAGCAACGAGCAATGTCTTGGGGCGACTGACGCACGTTGGCCGTATAATTTC
GGGCTTCGTCCGCAAGCGCC

Downstream 100 bases:

>100_bases
TTTCCCTCTTTCTCTCCAAGAGCCAACAAGACCATGTCGCAACAACTGCAATCGCTGATCGAACAAGCGTGGGAAGACCG
CGCCAACCTGTCGCCCAAGG

Product: succinyldiaminopimelate transaminase

Products: NA

Alternate protein names: DAP-AT; DAP-aminotransferase; LL-DAP-aminotransferase [H]

Number of amino acids: Translated: 417; Mature: 417

Protein sequence:

>417_residues
MLAQPPGPLRPIRSMPNTVNPRLSSLQPYPFEKLKALVKDVTPSPAHAPISFGIGEPKHPTPALVKDALTASLAGLANYP
TTAGSDALRQCIAAWLERRYGLPKVDAATEVLPVNGSREALFAFAQTVIDGSKPGARVLCPNPFYQIYEGSALLAGAQPL
FANSNPARNYAPDFDAITPEEWRNVQLVFVCSPGNPTGAVLTLEDWKQLFALSDRYGFVIASDECYSEIYFDEANPPLGA
LQAAHQLGRGFERLVMFSSLSKRSNVPGMRSGFVAGDAKLIKAYLLYRTYHGSAMNPAVQSASIAAWNDETHVRENRAQY
VRKFQSVTPMLAEVLDVALPDAAFYLWANVKRTGLSDTAFARELLAAKNVAVLPGSYLAREAHGVNPGQDYVRIALVAGV
DECLDGARRIVEFCQQR

Sequences:

>Translated_417_residues
MLAQPPGPLRPIRSMPNTVNPRLSSLQPYPFEKLKALVKDVTPSPAHAPISFGIGEPKHPTPALVKDALTASLAGLANYP
TTAGSDALRQCIAAWLERRYGLPKVDAATEVLPVNGSREALFAFAQTVIDGSKPGARVLCPNPFYQIYEGSALLAGAQPL
FANSNPARNYAPDFDAITPEEWRNVQLVFVCSPGNPTGAVLTLEDWKQLFALSDRYGFVIASDECYSEIYFDEANPPLGA
LQAAHQLGRGFERLVMFSSLSKRSNVPGMRSGFVAGDAKLIKAYLLYRTYHGSAMNPAVQSASIAAWNDETHVRENRAQY
VRKFQSVTPMLAEVLDVALPDAAFYLWANVKRTGLSDTAFARELLAAKNVAVLPGSYLAREAHGVNPGQDYVRIALVAGV
DECLDGARRIVEFCQQR
>Mature_417_residues
MLAQPPGPLRPIRSMPNTVNPRLSSLQPYPFEKLKALVKDVTPSPAHAPISFGIGEPKHPTPALVKDALTASLAGLANYP
TTAGSDALRQCIAAWLERRYGLPKVDAATEVLPVNGSREALFAFAQTVIDGSKPGARVLCPNPFYQIYEGSALLAGAQPL
FANSNPARNYAPDFDAITPEEWRNVQLVFVCSPGNPTGAVLTLEDWKQLFALSDRYGFVIASDECYSEIYFDEANPPLGA
LQAAHQLGRGFERLVMFSSLSKRSNVPGMRSGFVAGDAKLIKAYLLYRTYHGSAMNPAVQSASIAAWNDETHVRENRAQY
VRKFQSVTPMLAEVLDVALPDAAFYLWANVKRTGLSDTAFARELLAAKNVAVLPGSYLAREAHGVNPGQDYVRIALVAGV
DECLDGARRIVEFCQQR

Specific function: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily [H]

Homologues:

Organism=Homo sapiens, GI56713256, Length=401, Percent_Identity=23.4413965087282, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI56713254, Length=401, Percent_Identity=23.4413965087282, Blast_Score=76, Evalue=7e-14,
Organism=Homo sapiens, GI95147551, Length=403, Percent_Identity=20.8436724565757, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI169881279, Length=403, Percent_Identity=20.8436724565757, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI7705897, Length=338, Percent_Identity=25.1479289940828, Blast_Score=69, Evalue=9e-12,
Organism=Homo sapiens, GI33469970, Length=338, Percent_Identity=25.1479289940828, Blast_Score=69, Evalue=9e-12,
Organism=Escherichia coli, GI1788722, Length=395, Percent_Identity=28.1012658227848, Blast_Score=136, Evalue=3e-33,
Organism=Escherichia coli, GI1786816, Length=275, Percent_Identity=26.9090909090909, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1788627, Length=239, Percent_Identity=23.8493723849372, Blast_Score=65, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR019881
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.83 [H]

Molecular weight: Translated: 45352; Mature: 45352

Theoretical pI: Translated: 7.82; Mature: 7.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAQPPGPLRPIRSMPNTVNPRLSSLQPYPFEKLKALVKDVTPSPAHAPISFGIGEPKHP
CCCCCCCCCHHHHCCCCCCCCHHHCCCCCCHHHHHHHHHHCCCCCCCCCEEECCCCCCCC
TPALVKDALTASLAGLANYPTTAGSDALRQCIAAWLERRYGLPKVDAATEVLPVNGSREA
CHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCHHH
LFAFAQTVIDGSKPGARVLCPNPFYQIYEGSALLAGAQPLFANSNPARNYAPDFDAITPE
HHHHHHHHHCCCCCCCEEECCCCCHHHHCCCEEEECCCCCCCCCCCCCCCCCCCCCCCHH
EWRNVQLVFVCSPGNPTGAVLTLEDWKQLFALSDRYGFVIASDECYSEIYFDEANPPLGA
HHCCEEEEEEECCCCCCCEEEEHHHHHHHHHHCCCCCEEEECCHHHHHHEECCCCCCHHH
LQAAHQLGRGFERLVMFSSLSKRSNVPGMRSGFVAGDAKLIKAYLLYRTYHGSAMNPAVQ
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHC
SASIAAWNDETHVRENRAQYVRKFQSVTPMLAEVLDVALPDAAFYLWANVKRTGLSDTAF
CCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEHHHCCHHCCCCHHHH
ARELLAAKNVAVLPGSYLAREAHGVNPGQDYVRIALVAGVDECLDGARRIVEFCQQR
HHHHHHHCCEEECCCHHHHHHHCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLAQPPGPLRPIRSMPNTVNPRLSSLQPYPFEKLKALVKDVTPSPAHAPISFGIGEPKHP
CCCCCCCCCHHHHCCCCCCCCHHHCCCCCCHHHHHHHHHHCCCCCCCCCEEECCCCCCCC
TPALVKDALTASLAGLANYPTTAGSDALRQCIAAWLERRYGLPKVDAATEVLPVNGSREA
CHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCHHH
LFAFAQTVIDGSKPGARVLCPNPFYQIYEGSALLAGAQPLFANSNPARNYAPDFDAITPE
HHHHHHHHHCCCCCCCEEECCCCCHHHHCCCEEEECCCCCCCCCCCCCCCCCCCCCCCHH
EWRNVQLVFVCSPGNPTGAVLTLEDWKQLFALSDRYGFVIASDECYSEIYFDEANPPLGA
HHCCEEEEEEECCCCCCCEEEEHHHHHHHHHHCCCCCEEEECCHHHHHHEECCCCCCHHH
LQAAHQLGRGFERLVMFSSLSKRSNVPGMRSGFVAGDAKLIKAYLLYRTYHGSAMNPAVQ
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHC
SASIAAWNDETHVRENRAQYVRKFQSVTPMLAEVLDVALPDAAFYLWANVKRTGLSDTAF
CCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEHHHCCHHCCCCHHHH
ARELLAAKNVAVLPGSYLAREAHGVNPGQDYVRIALVAGVDECLDGARRIVEFCQQR
HHHHHHHCCEEECCCHHHHHHHCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA