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The map label for this gene is dapD

Identifier: 17546112

GI number: 17546112

Start: 1484398

End: 1485225

Strand: Reverse

Name: dapD

Synonym: RSc1393

Alternate gene names: 17546112

Gene position: 1485225-1484398 (Counterclockwise)

Preceding gene: 17546113

Following gene: 17546111

Centisome position: 39.96

GC content: 66.3

Gene sequence:

>828_bases
ATGTCGCAACAACTGCAATCGCTGATCGAACAAGCGTGGGAAGACCGCGCCAACCTGTCGCCCAAGGCCGCGCCGAACGA
TGTCCGCGCAGCCGTCGCCAACGTGATCGACCAGCTCGACCAGGGCGCGCTGCGCGTGGCCGAGAAGAAGGACGGCCAGT
GGATCGTCAACCAGTGGGTGAAGAAGGCCGTGCTGCTGTCGTTCCGCCTGGAAGACAACGCCCCGATGACGGCCGGCGGC
TTCACGCACTTCTATGACAAGGTGCCCAGCAAGTTCGCCAGCTACACGGCCGACGACTTCGCGCGCGGCGGCTTCCGCGT
GGTGCCGCCGGCCGTGGCGCGCCGCGGTTCGTTCATCGGCAAGAACGCCGTGCTGATGCCCTCGTACGTGAACATCGGCG
CCTACGTGGACGAAGGCACGATGGTCGACACCTGGGCCACGGTCGGCTCGTGCGCGCAGATCGGCAAGAACGTGCACCTG
TCGGGCGGCGTGGGCATCGGCGGCGTGCTGGAGCCGCTGCAGGCCAACCCGGTCATCATCGAGGACAACTGCTTCATCGG
CGCGCGCTCGGAAGTGGTGGAAGGCGTGATCGTCGAAGAGAACTCGGTGATCTCGATGGGCGTGTACCTGGGCCAGAGCA
CCAAGATCTACGACCGCGAAACCGGCGAGGTGCACTACGGCCGCGTGCCGGCCGGCTCGGTGGTGGTGCCGGGCAACCTG
CCGTCCAAGGACGGCACGTACAGCCTGTACTGCGCCGTGATCGTCAAGAAGGTCGACGCGCAGACGCGCGCCAAGACCAG
CCTCAACGAACTGCTGCGCGGCGATTGA

Upstream 100 bases:

>100_bases
GGTGGCCGGCGTGGACGAGTGCCTGGACGGCGCGCGCCGCATCGTCGAGTTCTGCCAGCAACGCTGATTTCCCTCTTTCT
CTCCAAGAGCCAACAAGACC

Downstream 100 bases:

>100_bases
GGGCAACGGCGGGCCTGTCCGGCAGTCCGGCGCACAGGCCCGCCCGAGCGCAGCGATGTCCGAACCGAACGCCACGGGCT
CACGCTGGGGCAAGCTGCGA

Product: 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase

Products: NA

Alternate protein names: Tetrahydrodipicolinate N-succinyltransferase; THDP succinyltransferase; THP succinyltransferase; Tetrahydropicolinate succinylase

Number of amino acids: Translated: 275; Mature: 274

Protein sequence:

>275_residues
MSQQLQSLIEQAWEDRANLSPKAAPNDVRAAVANVIDQLDQGALRVAEKKDGQWIVNQWVKKAVLLSFRLEDNAPMTAGG
FTHFYDKVPSKFASYTADDFARGGFRVVPPAVARRGSFIGKNAVLMPSYVNIGAYVDEGTMVDTWATVGSCAQIGKNVHL
SGGVGIGGVLEPLQANPVIIEDNCFIGARSEVVEGVIVEENSVISMGVYLGQSTKIYDRETGEVHYGRVPAGSVVVPGNL
PSKDGTYSLYCAVIVKKVDAQTRAKTSLNELLRGD

Sequences:

>Translated_275_residues
MSQQLQSLIEQAWEDRANLSPKAAPNDVRAAVANVIDQLDQGALRVAEKKDGQWIVNQWVKKAVLLSFRLEDNAPMTAGG
FTHFYDKVPSKFASYTADDFARGGFRVVPPAVARRGSFIGKNAVLMPSYVNIGAYVDEGTMVDTWATVGSCAQIGKNVHL
SGGVGIGGVLEPLQANPVIIEDNCFIGARSEVVEGVIVEENSVISMGVYLGQSTKIYDRETGEVHYGRVPAGSVVVPGNL
PSKDGTYSLYCAVIVKKVDAQTRAKTSLNELLRGD
>Mature_274_residues
SQQLQSLIEQAWEDRANLSPKAAPNDVRAAVANVIDQLDQGALRVAEKKDGQWIVNQWVKKAVLLSFRLEDNAPMTAGGF
THFYDKVPSKFASYTADDFARGGFRVVPPAVARRGSFIGKNAVLMPSYVNIGAYVDEGTMVDTWATVGSCAQIGKNVHLS
GGVGIGGVLEPLQANPVIIEDNCFIGARSEVVEGVIVEENSVISMGVYLGQSTKIYDRETGEVHYGRVPAGSVVVPGNLP
SKDGTYSLYCAVIVKKVDAQTRAKTSLNELLRGD

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; fourth step. [C]

COG id: COG2171

COG function: function code E; Tetrahydrodipicolinate N-succinyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family

Homologues:

Organism=Escherichia coli, GI1786362, Length=271, Percent_Identity=75.6457564575646, Blast_Score=399, Evalue=1e-112,

Paralogues:

None

Copy number: 420 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): DAPD_RALSO (Q8XZK2)

Other databases:

- EMBL:   AL646052
- RefSeq:   NP_519514.1
- ProteinModelPortal:   Q8XZK2
- SMR:   Q8XZK2
- GeneID:   1220217
- GenomeReviews:   AL646052_GR
- KEGG:   rso:RSc1393
- NMPDR:   fig|267608.1.peg.1393
- HOGENOM:   HBG704071
- OMA:   QWAKKAV
- ProtClustDB:   PRK11830
- BioCyc:   RSOL267608:RSC1393-MONOMER
- BRENDA:   2.3.1.117
- GO:   GO:0005737
- HAMAP:   MF_00811
- InterPro:   IPR005664
- InterPro:   IPR018357
- InterPro:   IPR023180
- InterPro:   IPR011004
- Gene3D:   G3DSA:1.10.166.10
- TIGRFAMs:   TIGR00965

Pfam domain/function: SSF51161 Trimer_LpxA_like

EC number: =2.3.1.117

Molecular weight: Translated: 29577; Mature: 29446

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: PS00101 HEXAPEP_TRANSFERASES

Important sites: BINDING 106-106 BINDING 143-143

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQQLQSLIEQAWEDRANLSPKAAPNDVRAAVANVIDQLDQGALRVAEKKDGQWIVNQWV
CCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
KKAVLLSFRLEDNAPMTAGGFTHFYDKVPSKFASYTADDFARGGFRVVPPAVARRGSFIG
HHHHHHEEEECCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHCCCCEECCHHHHHCCCCCC
KNAVLMPSYVNIGAYVDEGTMVDTWATVGSCAQIGKNVHLSGGVGIGGVLEPLQANPVII
CCEEECCCEEECCEEECCCCEEEHHHHHHHHHHHCCCEEECCCCCCCHHCCCCCCCCEEE
EDNCFIGARSEVVEGVIVEENSVISMGVYLGQSTKIYDRETGEVHYGRVPAGSVVVPGNL
ECCCEECCHHHHHCEEEECCCCEEEEEEEECCCCEEEECCCCCEEECCCCCCCEEECCCC
PSKDGTYSLYCAVIVKKVDAQTRAKTSLNELLRGD
CCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SQQLQSLIEQAWEDRANLSPKAAPNDVRAAVANVIDQLDQGALRVAEKKDGQWIVNQWV
CHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
KKAVLLSFRLEDNAPMTAGGFTHFYDKVPSKFASYTADDFARGGFRVVPPAVARRGSFIG
HHHHHHEEEECCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHCCCCEECCHHHHHCCCCCC
KNAVLMPSYVNIGAYVDEGTMVDTWATVGSCAQIGKNVHLSGGVGIGGVLEPLQANPVII
CCEEECCCEEECCEEECCCCEEEHHHHHHHHHHHCCCEEECCCCCCCHHCCCCCCCCEEE
EDNCFIGARSEVVEGVIVEENSVISMGVYLGQSTKIYDRETGEVHYGRVPAGSVVVPGNL
ECCCEECCHHHHHCEEEECCCCEEEEEEEECCCCEEEECCCCCEEECCCCCCCEEECCCC
PSKDGTYSLYCAVIVKKVDAQTRAKTSLNELLRGD
CCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852