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The map label for this gene is pmrF [H]

Identifier: 17546040

GI number: 17546040

Start: 1406145

End: 1407143

Strand: Reverse

Name: pmrF [H]

Synonym: RSc1321

Alternate gene names: 17546040

Gene position: 1407143-1406145 (Counterclockwise)

Preceding gene: 17546041

Following gene: 17546039

Centisome position: 37.86

GC content: 66.77

Gene sequence:

>999_bases
ATGAAGACACCCGCTCTCTCGGTCGTCATTCCCGTCTACAACGAGGAAGAGGGGCTCGCCGCCCTGTTCGCGCGCCTGTA
TCCCGCCCTCGATGCACTCGGCATCTCGTACGAGGTCGTGTTCATCAACGACGGCAGCCGGGACCGCTCCGCCGCCATGC
TCGCCGAGCAGTTCCGCGCGCGGCCCGACACCACCCGCGTGGTGCTGTTCAACGGCAACTACGGCCAGCACATGGCCATC
CTGGCCGGCTTCGAGCACGCCCGCGGCGAGCGCGTCATCACGCTGGACGCCGACCTGCAGAACCCGCCCGAAGAGATCGG
CCGCCTGGTCGCCAAGCTCGACGAAGGCTACGACTACGTCGGCACCATCCGCCGCAACCGGCAGGACACCTGGTTCCGCC
GCACCGCGTCGCGCGCCATGAACTCGCTGCGCGAGCGCATCACGCACATCAAGATGACCGACCAGGGCTGCATGCTGCGC
GCCTACAGCCGCCCCATCGTCGACACCATCAACCGCTGCCGCGAAGTCAACACCTTCATCCCGGCGCTGGGCTACACCTT
CGCCAAGAACCCGACCGAGATCGAAGTCGACCACGAAGAGCGCTTCGCGGGCGAATCCAAGTACTCGCTCTACAAGCTGA
TCCGCCTGAACTTCGACCTGGTGACGGGCTTCTCGGTGGTGCCGCTGCAGTGGTTCTCGGCGATCGGCATGCTGCTGTCG
CTCGCCTCGGCGGTGCTGTTCGTCCTGCTGGTCGTGCGCCGCTTCGTCCTTGGCGCGGAAGTCCAGGGCGTGTTCACGCT
GTTTGCCATCACGTTCTTCCTGATGGGGGTGCTGCTGTTCGGCATCGGGCTGCTGGGCGAGTACATCGGCCGGATCTACC
AGCAGGTGCGCGAGCGTCCGCGCTACCTGGTGCAGGGCGTGCTGGAAGACGCGCCCAACCTGCACGAGGCCGGCGCCGCC
GACCTGAACGTGTCCAAGGCGCAGCGGGGCGCGGCATGA

Upstream 100 bases:

>100_bases
GGCGCGCCATCGTGACGCTGCCGATGTTCGCCGCCATGGAAGATTCCGACGTGGACCGCGTAGTCAATGCGGTCCGCCAA
CTCTGCATCCAACACCAATA

Downstream 100 bases:

>100_bases
CGCGGCGCGCGGTCGTCTTTGCGTACCACAACGTCGGCGTGCGCTGCCTGCGCGTGCTGGCCGCGCGCGGCATCCAGATC
GAGCTGGTGGTCACGCACGA

Product: polymixin resistance glycosyltransferase transmembrane protein

Products: NA

Alternate protein names: Undecaprenyl-phosphate Ara4FN transferase; Ara4FN transferase [H]

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MKTPALSVVIPVYNEEEGLAALFARLYPALDALGISYEVVFINDGSRDRSAAMLAEQFRARPDTTRVVLFNGNYGQHMAI
LAGFEHARGERVITLDADLQNPPEEIGRLVAKLDEGYDYVGTIRRNRQDTWFRRTASRAMNSLRERITHIKMTDQGCMLR
AYSRPIVDTINRCREVNTFIPALGYTFAKNPTEIEVDHEERFAGESKYSLYKLIRLNFDLVTGFSVVPLQWFSAIGMLLS
LASAVLFVLLVVRRFVLGAEVQGVFTLFAITFFLMGVLLFGIGLLGEYIGRIYQQVRERPRYLVQGVLEDAPNLHEAGAA
DLNVSKAQRGAA

Sequences:

>Translated_332_residues
MKTPALSVVIPVYNEEEGLAALFARLYPALDALGISYEVVFINDGSRDRSAAMLAEQFRARPDTTRVVLFNGNYGQHMAI
LAGFEHARGERVITLDADLQNPPEEIGRLVAKLDEGYDYVGTIRRNRQDTWFRRTASRAMNSLRERITHIKMTDQGCMLR
AYSRPIVDTINRCREVNTFIPALGYTFAKNPTEIEVDHEERFAGESKYSLYKLIRLNFDLVTGFSVVPLQWFSAIGMLLS
LASAVLFVLLVVRRFVLGAEVQGVFTLFAITFFLMGVLLFGIGLLGEYIGRIYQQVRERPRYLVQGVLEDAPNLHEAGAA
DLNVSKAQRGAA
>Mature_332_residues
MKTPALSVVIPVYNEEEGLAALFARLYPALDALGISYEVVFINDGSRDRSAAMLAEQFRARPDTTRVVLFNGNYGQHMAI
LAGFEHARGERVITLDADLQNPPEEIGRLVAKLDEGYDYVGTIRRNRQDTWFRRTASRAMNSLRERITHIKMTDQGCMLR
AYSRPIVDTINRCREVNTFIPALGYTFAKNPTEIEVDHEERFAGESKYSLYKLIRLNFDLVTGFSVVPLQWFSAIGMLLS
LASAVLFVLLVVRRFVLGAEVQGVFTLFAITFFLMGVLLFGIGLLGEYIGRIYQQVRERPRYLVQGVLEDAPNLHEAGAA
DLNVSKAQRGAA

Specific function: Catalyzes the transfer of 4-deoxy-4-formamido-L- arabinose from UDP to undecaprenyl phosphate. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides [H]

COG id: COG0463

COG function: function code M; Glycosyltransferases involved in cell wall biogenesis

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 2 family [H]

Homologues:

Organism=Homo sapiens, GI4503363, Length=238, Percent_Identity=27.3109243697479, Blast_Score=72, Evalue=6e-13,
Organism=Escherichia coli, GI1788588, Length=313, Percent_Identity=53.0351437699681, Blast_Score=327, Evalue=5e-91,
Organism=Escherichia coli, GI1788692, Length=303, Percent_Identity=30.6930693069307, Blast_Score=166, Evalue=3e-42,
Organism=Saccharomyces cerevisiae, GI6325441, Length=117, Percent_Identity=29.0598290598291, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24585265, Length=236, Percent_Identity=25.8474576271186, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022857
- InterPro:   IPR001173 [H]

Pfam domain/function: PF00535 Glycos_transf_2 [H]

EC number: =2.7.8.30 [H]

Molecular weight: Translated: 37293; Mature: 37293

Theoretical pI: Translated: 7.61; Mature: 7.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTPALSVVIPVYNEEEGLAALFARLYPALDALGISYEVVFINDGSRDRSAAMLAEQFRA
CCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCHHHHHHHHHHHC
RPDTTRVVLFNGNYGQHMAILAGFEHARGERVITLDADLQNPPEEIGRLVAKLDEGYDYV
CCCCEEEEEEECCCCCHHHHEECHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCHH
GTIRRNRQDTWFRRTASRAMNSLRERITHIKMTDQGCMLRAYSRPIVDTINRCREVNTFI
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHCCCHHHHHHHHHHHHHHH
PALGYTFAKNPTEIEVDHEERFAGESKYSLYKLIRLNFDLVTGFSVVPLQWFSAIGMLLS
HHHCHHHCCCCCEEEECHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
LASAVLFVLLVVRRFVLGAEVQGVFTLFAITFFLMGVLLFGIGLLGEYIGRIYQQVRERP
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RYLVQGVLEDAPNLHEAGAADLNVSKAQRGAA
HHHHHHHHHCCCCCHHCCCCCCCHHHHHCCCC
>Mature Secondary Structure
MKTPALSVVIPVYNEEEGLAALFARLYPALDALGISYEVVFINDGSRDRSAAMLAEQFRA
CCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCHHHHHHHHHHHC
RPDTTRVVLFNGNYGQHMAILAGFEHARGERVITLDADLQNPPEEIGRLVAKLDEGYDYV
CCCCEEEEEEECCCCCHHHHEECHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCHH
GTIRRNRQDTWFRRTASRAMNSLRERITHIKMTDQGCMLRAYSRPIVDTINRCREVNTFI
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHCCCHHHHHHHHHHHHHHH
PALGYTFAKNPTEIEVDHEERFAGESKYSLYKLIRLNFDLVTGFSVVPLQWFSAIGMLLS
HHHCHHHCCCCCEEEECHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
LASAVLFVLLVVRRFVLGAEVQGVFTLFAITFFLMGVLLFGIGLLGEYIGRIYQQVRERP
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RYLVQGVLEDAPNLHEAGAADLNVSKAQRGAA
HHHHHHHHHCCCCCHHCCCCCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA