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The map label for this gene is arnA [H]

Identifier: 17546039

GI number: 17546039

Start: 1405213

End: 1406148

Strand: Reverse

Name: arnA [H]

Synonym: RSc1320

Alternate gene names: 17546039

Gene position: 1406148-1405213 (Counterclockwise)

Preceding gene: 17546040

Following gene: 17546038

Centisome position: 37.84

GC content: 68.16

Gene sequence:

>936_bases
ATGACGCGGCGCGCGGTCGTCTTTGCGTACCACAACGTCGGCGTGCGCTGCCTGCGCGTGCTGGCCGCGCGCGGCATCCA
GATCGAGCTGGTGGTCACGCACGAGGACAGCGCCACCGAGAACATCTGGTTCGGCAGCGTGCGCGCCACCGCGCAGGAGC
TCGGCATCCCCTTCGTCACGCCGGAAGACGCGCGCGGCGAAGACCTGTTCGCCCGCATCGCCGCCATCGCGCCGGATTTC
ATTTTCTCGTTCTACTACCGGCACATGATCCCGGTGCGCCTGCTCGGCCTGGCCAGGCACGGCGCGTTCAACATGCACGG
CTCGCTGCTGCCGAAGTACCGTGGCCGCGTGCCGACCAACTGGGCCGTCCTGCACGGCGAGACCGAAAGCGGCGCCACCC
TGCACGAAATGGTCGAAAAGCCGGATGCCGGCTATATCGTCGACCAGACCATCGTGCCGATCCTGCCGGACGACACGGCC
CATGAAGTCTTCGAAAAGACGACCGTGGCGGCCGAACAGACGCTCTGGCGCGTGCTGCCGGACATGATCGCCGGCCGGAT
TCCGCAGCGCCCCAACCGGCTCGAAGACGGCAGCTACTTCGGCGGCCGCAAGCCCGAAGACGGCCGCATCGACTGGTCCC
GGCCCGCCCAGCAGGTCTACAACCTCGTGCGCGCCGTGGCGCCGCCCTATCCGGGCGCCTTCACGGACGCCGGCGGTGAA
CGCTACATCGTCGCGCGGGCCCGCCTGGCGCGACAGTCCTTCTCGAATTTGCCCCCAGGGTTGCACGTCGTGGATAATGC
GATGTTTGGCGTGTGCGGCGATGGGGGAGCCATCGCCATCCACGAGCTCTGGCGCGTCGAGCCCCAGGCGCCGTCCACGA
CCACGGTCGTGACTGCGCAACAGCTCGCCAACCGGCTCGCCCTCTCCTGTTCTTGA

Upstream 100 bases:

>100_bases
GTCCGCGCTACCTGGTGCAGGGCGTGCTGGAAGACGCGCCCAACCTGCACGAGGCCGGCGCCGCCGACCTGAACGTGTCC
AAGGCGCAGCGGGGCGCGGC

Downstream 100 bases:

>100_bases
GTTTGCCTTCATGAAGAAAGTACTGATCCTCGGCGTCAACGGCTTTATCGGCCACCACCTGTCCAAGCGCATCCTGGAGA
GCACGGACCCGGAAATCTCC

Product: formyltransferase

Products: NA

Alternate protein names: UDP-4-amino-4-deoxy-L-arabinose formyltransferase; ArnAFT; UDP-L-Ara4N formyltransferase; UDP-glucuronic acid oxidase, UDP-4-keto-hexauronic acid decarboxylating; ArnADH; UDP-GlcUA decarboxylase; UDP-glucuronic acid dehydrogenase [H]

Number of amino acids: Translated: 311; Mature: 310

Protein sequence:

>311_residues
MTRRAVVFAYHNVGVRCLRVLAARGIQIELVVTHEDSATENIWFGSVRATAQELGIPFVTPEDARGEDLFARIAAIAPDF
IFSFYYRHMIPVRLLGLARHGAFNMHGSLLPKYRGRVPTNWAVLHGETESGATLHEMVEKPDAGYIVDQTIVPILPDDTA
HEVFEKTTVAAEQTLWRVLPDMIAGRIPQRPNRLEDGSYFGGRKPEDGRIDWSRPAQQVYNLVRAVAPPYPGAFTDAGGE
RYIVARARLARQSFSNLPPGLHVVDNAMFGVCGDGGAIAIHELWRVEPQAPSTTTVVTAQQLANRLALSCS

Sequences:

>Translated_311_residues
MTRRAVVFAYHNVGVRCLRVLAARGIQIELVVTHEDSATENIWFGSVRATAQELGIPFVTPEDARGEDLFARIAAIAPDF
IFSFYYRHMIPVRLLGLARHGAFNMHGSLLPKYRGRVPTNWAVLHGETESGATLHEMVEKPDAGYIVDQTIVPILPDDTA
HEVFEKTTVAAEQTLWRVLPDMIAGRIPQRPNRLEDGSYFGGRKPEDGRIDWSRPAQQVYNLVRAVAPPYPGAFTDAGGE
RYIVARARLARQSFSNLPPGLHVVDNAMFGVCGDGGAIAIHELWRVEPQAPSTTTVVTAQQLANRLALSCS
>Mature_310_residues
TRRAVVFAYHNVGVRCLRVLAARGIQIELVVTHEDSATENIWFGSVRATAQELGIPFVTPEDARGEDLFARIAAIAPDFI
FSFYYRHMIPVRLLGLARHGAFNMHGSLLPKYRGRVPTNWAVLHGETESGATLHEMVEKPDAGYIVDQTIVPILPDDTAH
EVFEKTTVAAEQTLWRVLPDMIAGRIPQRPNRLEDGSYFGGRKPEDGRIDWSRPAQQVYNLVRAVAPPYPGAFTDAGGER
YIVARARLARQSFSNLPPGLHVVDNAMFGVCGDGGAIAIHELWRVEPQAPSTTTVVTAQQLANRLALSCS

Specific function: Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabin

COG id: COG0223

COG function: function code J; Methionyl-tRNA formyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the sugar epimerase family. UDP-glucuronic acid decarboxylase subfamily [H]

Homologues:

Organism=Homo sapiens, GI21614513, Length=183, Percent_Identity=26.2295081967213, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI238814322, Length=214, Percent_Identity=25.2336448598131, Blast_Score=73, Evalue=4e-13,
Organism=Escherichia coli, GI1788589, Length=305, Percent_Identity=42.2950819672131, Blast_Score=229, Evalue=2e-61,
Organism=Escherichia coli, GI1789683, Length=305, Percent_Identity=25.9016393442623, Blast_Score=92, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR021168
- InterPro:   IPR001509
- InterPro:   IPR005793
- InterPro:   IPR002376
- InterPro:   IPR011034
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase; PF02911 Formyl_trans_C; PF00551 Formyl_trans_N [H]

EC number: =2.1.2.13; =1.1.1.305 [H]

Molecular weight: Translated: 34321; Mature: 34189

Theoretical pI: Translated: 7.07; Mature: 7.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRRAVVFAYHNVGVRCLRVLAARGIQIELVVTHEDSATENIWFGSVRATAQELGIPFVT
CCCCEEEEEEHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCEEECHHHHHHHHCCCCCCC
PEDARGEDLFARIAAIAPDFIFSFYYRHMIPVRLLGLARHGAFNMHGSLLPKYRGRVPTN
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCCC
WAVLHGETESGATLHEMVEKPDAGYIVDQTIVPILPDDTAHEVFEKTTVAAEQTLWRVLP
EEEEECCCCCCCHHHHHHCCCCCCEEECCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHH
DMIAGRIPQRPNRLEDGSYFGGRKPEDGRIDWSRPAQQVYNLVRAVAPPYPGAFTDAGGE
HHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCC
RYIVARARLARQSFSNLPPGLHVVDNAMFGVCGDGGAIAIHELWRVEPQAPSTTTVVTAQ
EEEHHHHHHHHHHHHCCCCCCEECCCCEEEEECCCCEEEEEHHHCCCCCCCCCCCEEEHH
QLANRLALSCS
HHHHHHHCCCC
>Mature Secondary Structure 
TRRAVVFAYHNVGVRCLRVLAARGIQIELVVTHEDSATENIWFGSVRATAQELGIPFVT
CCCEEEEEEHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCEEECHHHHHHHHCCCCCCC
PEDARGEDLFARIAAIAPDFIFSFYYRHMIPVRLLGLARHGAFNMHGSLLPKYRGRVPTN
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCCC
WAVLHGETESGATLHEMVEKPDAGYIVDQTIVPILPDDTAHEVFEKTTVAAEQTLWRVLP
EEEEECCCCCCCHHHHHHCCCCCCEEECCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHH
DMIAGRIPQRPNRLEDGSYFGGRKPEDGRIDWSRPAQQVYNLVRAVAPPYPGAFTDAGGE
HHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCC
RYIVARARLARQSFSNLPPGLHVVDNAMFGVCGDGGAIAIHELWRVEPQAPSTTTVVTAQ
EEEHHHHHHHHHHHHCCCCCCEECCCCEEEEECCCCEEEEEHHHCCCCCCCCCCCEEEHH
QLANRLALSCS
HHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA